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The map label for this gene is tcmN [H]

Identifier: 91787649

GI number: 91787649

Start: 1826706

End: 1827719

Strand: Direct

Name: tcmN [H]

Synonym: Bpro_1767

Alternate gene names: 91787649

Gene position: 1826706-1827719 (Clockwise)

Preceding gene: 91787648

Following gene: 91787653

Centisome position: 35.13

GC content: 67.06

Gene sequence:

>1014_bases
GTGGCACATGACGCTACCGATCCGGCGACCACGCTCCACCGCCTGGTGACCGGCTATCAGGTGTCGCAAGCGATTCACGT
CGCGGCAACGCTTGGCATCGCCGACCTGCTCGCCGATGCGAGCCACACCGGTGACGAGCTGGCTGCGCTCACCAACACCC
ATCCACCCACGCTGTACCGTCTGCTGCGCGCACTGGCGAGCGTCGAAGTCTTGCATGAGCTCGACGGTCGGCGCTTCGAG
CTGACACCGCTCGGTGAGCCACTGCGCTCGGGCGTTCCGGGCTCGATGGTCGACCTGGCCGCTTACATGGGCCGTCCCTA
CCGCCTGCAGGCATGGGGCGGGCTGCTGCACAGCGTTCGCACCGGCGAGAACGCCTTCCGGCATATATATGGCACCGACG
TGTGGACGTACCGCTCGACCCGTCCGGACGAAAGTGCCATCTTCGACCGCGCGATGACCTCGCTCTCGCGCGGCGCCACT
GCCGCGCTGCTCGCCGCGGTCGACTTCGGGGGATTTCGCACGGTCGTTGACGTCGGTGGCGGCAACGGCGCCCTGCTCGC
GGCAATCCTGGCCGCGCACTCCCATGTCCAGGGCGTGTTGTTTGACCAGCCGCACGTGGTGTCAGGCGCCACCACGTTGC
TCGAGCACGCCGGCGTTGCCGATCGCTGCCGGACGGTCGGCGGCAGCTTCTTCGAATCGGTCCCGGAGCATGCCGATGCC
TACGTGCTTCGCGCCGTCATCCACGATTGGGACGACGACGCGTCCATTCGCATTCTCACGGCGGTCAGGCACGCCTTGGC
GGACAACGGCCGGGTGCTGATCGTTGAGTACATGATCGCGCCTCCGAACGAAGGGCGCGAAGCTAAGTTCTCCGACCTGA
ACATGCTCGTCGGCCCGGGCGGCCGAGAGCGAACGCGCGAAGAGTTCGTCGCGCTTCTCGAAGCGTCTGGTCTGCGGTTG
GCGCGCGTGATTGCGGCCGGAAGCCAATCCGTTGCTGAAGCCGTGCGCGCGTGA

Upstream 100 bases:

>100_bases
CACACCGGCAGAGCTGGCGGCTCGCATCGCGGCGGAACGACGCTATTGGGAGCCGATCATCCGCGCCACCGGCATTCGGG
CCGAGTGATCTGGAGCGACC

Downstream 100 bases:

>100_bases
ACTGTTCAAGCGAGCTGTTCAGGCGCGCCCTCGCGTGAGCCGGCGAGTGAGAAGGCGCGAGCGATCACTGCTCAGTTCGT
CACGATTTCTCCGACGAAGA

Product: hydroxyneurosporene-O-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAHDATDPATTLHRLVTGYQVSQAIHVAATLGIADLLADASHTGDELAALTNTHPPTLYRLLRALASVEVLHELDGRRFE
LTPLGEPLRSGVPGSMVDLAAYMGRPYRLQAWGGLLHSVRTGENAFRHIYGTDVWTYRSTRPDESAIFDRAMTSLSRGAT
AALLAAVDFGGFRTVVDVGGGNGALLAAILAAHSHVQGVLFDQPHVVSGATTLLEHAGVADRCRTVGGSFFESVPEHADA
YVLRAVIHDWDDDASIRILTAVRHALADNGRVLIVEYMIAPPNEGREAKFSDLNMLVGPGGRERTREEFVALLEASGLRL
ARVIAAGSQSVAEAVRA

Sequences:

>Translated_337_residues
MAHDATDPATTLHRLVTGYQVSQAIHVAATLGIADLLADASHTGDELAALTNTHPPTLYRLLRALASVEVLHELDGRRFE
LTPLGEPLRSGVPGSMVDLAAYMGRPYRLQAWGGLLHSVRTGENAFRHIYGTDVWTYRSTRPDESAIFDRAMTSLSRGAT
AALLAAVDFGGFRTVVDVGGGNGALLAAILAAHSHVQGVLFDQPHVVSGATTLLEHAGVADRCRTVGGSFFESVPEHADA
YVLRAVIHDWDDDASIRILTAVRHALADNGRVLIVEYMIAPPNEGREAKFSDLNMLVGPGGRERTREEFVALLEASGLRL
ARVIAAGSQSVAEAVRA
>Mature_336_residues
AHDATDPATTLHRLVTGYQVSQAIHVAATLGIADLLADASHTGDELAALTNTHPPTLYRLLRALASVEVLHELDGRRFEL
TPLGEPLRSGVPGSMVDLAAYMGRPYRLQAWGGLLHSVRTGENAFRHIYGTDVWTYRSTRPDESAIFDRAMTSLSRGATA
ALLAAVDFGGFRTVVDVGGGNGALLAAILAAHSHVQGVLFDQPHVVSGATTLLEHAGVADRCRTVGGSFFESVPEHADAY
VLRAVIHDWDDDASIRILTAVRHALADNGRVLIVEYMIAPPNEGREAKFSDLNMLVGPGGRERTREEFVALLEASGLRLA
RVIAAGSQSVAEAVRA

Specific function: The N-terminal domain enhances the formation of an early, partially cyclized intermediate, while the C-terminal domain catalyzes the 3-O-methylation of one or more later intermediates in the biosynthetic pathway. Catalyzes the methylation of tetracenomyci

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI117553627, Length=333, Percent_Identity=25.5255255255255, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI291045181, Length=333, Percent_Identity=25.5255255255255, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI291045183, Length=333, Percent_Identity=25.5255255255255, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001077
- InterPro:   IPR005031
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00891 Methyltransf_2; PF03364 Polyketide_cyc [H]

EC number: NA

Molecular weight: Translated: 36022; Mature: 35891

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDATDPATTLHRLVTGYQVSQAIHVAATLGIADLLADASHTGDELAALTNTHPPTLYR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHH
LLRALASVEVLHELDGRRFELTPLGEPLRSGVPGSMVDLAAYMGRPYRLQAWGGLLHSVR
HHHHHHHHHHHHHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHH
TGENAFRHIYGTDVWTYRSTRPDESAIFDRAMTSLSRGATAALLAAVDFGGFRTVVDVGG
CCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECC
GNGALLAAILAAHSHVQGVLFDQPHVVSGATTLLEHAGVADRCRTVGGSFFESVPEHADA
CCHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
YVLRAVIHDWDDDASIRILTAVRHALADNGRVLIVEYMIAPPNEGREAKFSDLNMLVGPG
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCC
GRERTREEFVALLEASGLRLARVIAAGSQSVAEAVRA
CCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
AHDATDPATTLHRLVTGYQVSQAIHVAATLGIADLLADASHTGDELAALTNTHPPTLYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHH
LLRALASVEVLHELDGRRFELTPLGEPLRSGVPGSMVDLAAYMGRPYRLQAWGGLLHSVR
HHHHHHHHHHHHHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHH
TGENAFRHIYGTDVWTYRSTRPDESAIFDRAMTSLSRGATAALLAAVDFGGFRTVVDVGG
CCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECC
GNGALLAAILAAHSHVQGVLFDQPHVVSGATTLLEHAGVADRCRTVGGSFFESVPEHADA
CCHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
YVLRAVIHDWDDDASIRILTAVRHALADNGRVLIVEYMIAPPNEGREAKFSDLNMLVGPG
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCC
GRERTREEFVALLEASGLRLARVIAAGSQSVAEAVRA
CCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1548230; 2684656 [H]