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The map label for this gene is aphA [H]

Identifier: 91787623

GI number: 91787623

Start: 1799183

End: 1801756

Strand: Reverse

Name: aphA [H]

Synonym: Bpro_1741

Alternate gene names: 91787623

Gene position: 1801756-1799183 (Counterclockwise)

Preceding gene: 91787624

Following gene: 91787622

Centisome position: 34.65

GC content: 63.75

Gene sequence:

>2574_bases
ATGCCAAACACCTCTCTGCCTGAATCCGCCTACCTGCCGGCCAGAGATCTGCTGGAAAAGCGTTACATACGCGGACTGCG
GTCTGTACTGCTGATGCTGCTGCTGGGCCTGCCGCTGGTCCTGGGTCTGTCGGTGGTGCAACACAGCGCAGGCGCGCAGA
TCGCCATTGTGGCGGTGGCTCTCGTGCTGACCGGCCTGGCCTACTGGCTGCTGCACCGCGGCCACTACCCATTGGCCAGC
CAACTGGTGGTTTTCTCCCTGATCGCCTGCTCGGTGGCGGGCATTCTTGCCTACGGATCGGTACGCAATGCCCTGGTGCT
GGGTTTTGCCGGCGCCGTGGTGACAGCCGGCATGACGCTGGGTAAAAGAACACTGATCCTGTCCGTGGCACTCAGCGCGG
CAGCTCTTGCGGCACTGACATGGGCCGAGGCGTCCGGGTTGCTGGTCAAGCCCGATTTCGGGGTCGGCCTGCGGTTCTGG
CTGATCCTCGTGCTGCTATTGACAGGCATCGCCGTCAGTGTCTACACCAGCCGCCAGGTGGTGTTGCAGGCGCTGCGCGA
GCAGCATACCGAGCTGAAGCGGCGCGAACAGGCCGAATATGAACTGCTGCTGAGCGAAACCCGGTTCAGCCGGATATTCC
GCAGCAGCCCGGCTGCGATCGTCGTGCAGGCCATGAATGACATGACGGTGCTGGACGTCAACCCGGCCTTCGAACGCCTG
TATGGCTACTCCCGTGGCGAATTCATCGGCAGCACCGACGCCGCGCTCTGGGATGACCCCAAGGCACGCAAAGCCTTCCT
GCGCCAGATGGAAGCGACCGACCGCGTGATCAACCTCCCGCTGGATGGACGCAGAAAAGACGGCCAGCTGATCAACGTCC
TGCTGTCGTCCGAGATCGAGGGAAGGGGCCCGGAACGCATCGTGGTGTCCACCATCACCGACGCCACCGCCGAAACCCAG
GCCCGGCAGGCGGCGCGCCAGTCGGCGGAGCTGTTTTCCAAGGCCTTCGACTTCAGCCCCATCAACATGACCATCACCCG
GGTCTCCGACGGAAAATTTCTGGCCGTCAATTCCGCCGAAGACCTGGTGCAGGGTTTTACAGCCTCGGAGCTGATCGGGC
GCACCTCGGTGGACGCCGGCGTCTGGCGCGATGAAGAGGAGCGCAAGAAGTTCATGGAGGAACTGCGCGCGCAGGGGCAG
GTTCAAAGCCACGACCGGCAGATGCGCCACAAGGATGGCACCCTGATCGACTGCCGGATGTGGGCGGTGATTGTCGAGAT
CGCGGGCGAGCCCTGCGTACTCAGCTCGACCATCAACATCACCGAACAGAAGCGGCGCGAGGCTCTGCTGATTGATGTGG
CAAGAAGCCTGTCGACTGAAACCGGCGAAGCCTTCTTCCGCTCCGTGGTACAGCATGTAGCCAAGGCCATGGAGGCCGAC
CTGGTGATGGTGGGCGAAACGGCTGACGACCAGAGCGTTACCTCGCTGGCCATGGTCCAGGACGGCCTGCTGCAGCCCAA
CATACGTTATGAACTGGCCGGCACACCCTGCGACATGGTCATCGGACACAGCGATCTCTGTGTCTATGGCGACGGTGTGC
AACAGCTGTTTCCGCAAGACGGGTTCCTGGTAGACGGCGGCTACCGGGCCTATGCCGGCGTGGCGCTGCGTGATGCGGAC
GGCACCCCTATCGGCATCGTCAACGCCCTCTGGCGCAAGCCCCAGCCCCTGTCGCCGGATCGGGACGCACTGTTGCAGAT
TTTTGCCAGCCGCATCACGGCCGAGCTGATGCGGCTGCGCCGCGACCGCGAAATCGCCCGCCTCAATGAAACGCTGGAGC
AGCGTGTCAGCGAACGCACCGACCAGCTCAGGGCGACCAACGCCGAACTCGAGTCTTTCGGCTATTCGGTATCGCACGAC
CTGCAGTCGCCGCTGCGCAGCATTGAAGGCTTCAGCGTGCTGCTGGCGCGCCGGCTCAGGGGGCGGCTCAGCCATGAGGA
GCAGCGTCTGTTTGATCGGGTCAAGGCCAACGTCGTGCGCATGCACGAGCTGATCAACGACCTGCTGGCGCTCGCCCGGG
TCAGCAAAGGCAAGCTGCTGCTTGAGCAGGTCAACCTCAGTGCGCTGGCGCAGCAGGTCATCGCGCAGGAGCGGCAGCGC
GAGCCGCAGCGCCAGGTGCGGGTGACCGTCCAGCCCGGCATCAGCGCCCACTGCGACAGCAAGTTCGCCCGCATCATTCT
GGAAAACCTGATCGGCAATGCCTGGAAATACTCACGCGCACAAGCCGATGCGCAGATCGAATTTGGCGCCTTGCCGACCC
GCGAAGGCGGCCGCAAGATGCTGTTTGTGCGCGACAACGGCGCCGGCTTCAACATGGCCTACTCGGCCAGCCTGTTCAAG
CCCTTTCACCGGCTGCACCATGAGCACGAGTTCGAAGGCAGCGGCATCGGCCTGGCCACCGTGCACCGCATTCTTGAACG
GCACGGCGGCGTGATACGCGCCGAGTCGACCGAAGGTGCTGGCGCCTGCTTTTACTTCTCGTTCGATCCGCGCTTCGGGC
CGGGTGCCGGTTAA

Upstream 100 bases:

>100_bases
ACAGGGAGCCTGAGGGGGCCTGGAAGCGCCGGATGAGTATTTGAAATGTTCAGCCAACCGCGATCGCGGTGCTTTAGCAT
CGGGTTGAACCGAACATCGC

Downstream 100 bases:

>100_bases
ATCGACCTCAAGCCCAACAACAACGGACGCAAGCAGCTTCTATTGATGTTGACCCAACCCATGGCACCTTCCGTTTCGGG
CTCAGCTACCAGGCCAGGAC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 857; Mature: 856

Protein sequence:

>857_residues
MPNTSLPESAYLPARDLLEKRYIRGLRSVLLMLLLGLPLVLGLSVVQHSAGAQIAIVAVALVLTGLAYWLLHRGHYPLAS
QLVVFSLIACSVAGILAYGSVRNALVLGFAGAVVTAGMTLGKRTLILSVALSAAALAALTWAEASGLLVKPDFGVGLRFW
LILVLLLTGIAVSVYTSRQVVLQALREQHTELKRREQAEYELLLSETRFSRIFRSSPAAIVVQAMNDMTVLDVNPAFERL
YGYSRGEFIGSTDAALWDDPKARKAFLRQMEATDRVINLPLDGRRKDGQLINVLLSSEIEGRGPERIVVSTITDATAETQ
ARQAARQSAELFSKAFDFSPINMTITRVSDGKFLAVNSAEDLVQGFTASELIGRTSVDAGVWRDEEERKKFMEELRAQGQ
VQSHDRQMRHKDGTLIDCRMWAVIVEIAGEPCVLSSTINITEQKRREALLIDVARSLSTETGEAFFRSVVQHVAKAMEAD
LVMVGETADDQSVTSLAMVQDGLLQPNIRYELAGTPCDMVIGHSDLCVYGDGVQQLFPQDGFLVDGGYRAYAGVALRDAD
GTPIGIVNALWRKPQPLSPDRDALLQIFASRITAELMRLRRDREIARLNETLEQRVSERTDQLRATNAELESFGYSVSHD
LQSPLRSIEGFSVLLARRLRGRLSHEEQRLFDRVKANVVRMHELINDLLALARVSKGKLLLEQVNLSALAQQVIAQERQR
EPQRQVRVTVQPGISAHCDSKFARIILENLIGNAWKYSRAQADAQIEFGALPTREGGRKMLFVRDNGAGFNMAYSASLFK
PFHRLHHEHEFEGSGIGLATVHRILERHGGVIRAESTEGAGACFYFSFDPRFGPGAG

Sequences:

>Translated_857_residues
MPNTSLPESAYLPARDLLEKRYIRGLRSVLLMLLLGLPLVLGLSVVQHSAGAQIAIVAVALVLTGLAYWLLHRGHYPLAS
QLVVFSLIACSVAGILAYGSVRNALVLGFAGAVVTAGMTLGKRTLILSVALSAAALAALTWAEASGLLVKPDFGVGLRFW
LILVLLLTGIAVSVYTSRQVVLQALREQHTELKRREQAEYELLLSETRFSRIFRSSPAAIVVQAMNDMTVLDVNPAFERL
YGYSRGEFIGSTDAALWDDPKARKAFLRQMEATDRVINLPLDGRRKDGQLINVLLSSEIEGRGPERIVVSTITDATAETQ
ARQAARQSAELFSKAFDFSPINMTITRVSDGKFLAVNSAEDLVQGFTASELIGRTSVDAGVWRDEEERKKFMEELRAQGQ
VQSHDRQMRHKDGTLIDCRMWAVIVEIAGEPCVLSSTINITEQKRREALLIDVARSLSTETGEAFFRSVVQHVAKAMEAD
LVMVGETADDQSVTSLAMVQDGLLQPNIRYELAGTPCDMVIGHSDLCVYGDGVQQLFPQDGFLVDGGYRAYAGVALRDAD
GTPIGIVNALWRKPQPLSPDRDALLQIFASRITAELMRLRRDREIARLNETLEQRVSERTDQLRATNAELESFGYSVSHD
LQSPLRSIEGFSVLLARRLRGRLSHEEQRLFDRVKANVVRMHELINDLLALARVSKGKLLLEQVNLSALAQQVIAQERQR
EPQRQVRVTVQPGISAHCDSKFARIILENLIGNAWKYSRAQADAQIEFGALPTREGGRKMLFVRDNGAGFNMAYSASLFK
PFHRLHHEHEFEGSGIGLATVHRILERHGGVIRAESTEGAGACFYFSFDPRFGPGAG
>Mature_856_residues
PNTSLPESAYLPARDLLEKRYIRGLRSVLLMLLLGLPLVLGLSVVQHSAGAQIAIVAVALVLTGLAYWLLHRGHYPLASQ
LVVFSLIACSVAGILAYGSVRNALVLGFAGAVVTAGMTLGKRTLILSVALSAAALAALTWAEASGLLVKPDFGVGLRFWL
ILVLLLTGIAVSVYTSRQVVLQALREQHTELKRREQAEYELLLSETRFSRIFRSSPAAIVVQAMNDMTVLDVNPAFERLY
GYSRGEFIGSTDAALWDDPKARKAFLRQMEATDRVINLPLDGRRKDGQLINVLLSSEIEGRGPERIVVSTITDATAETQA
RQAARQSAELFSKAFDFSPINMTITRVSDGKFLAVNSAEDLVQGFTASELIGRTSVDAGVWRDEEERKKFMEELRAQGQV
QSHDRQMRHKDGTLIDCRMWAVIVEIAGEPCVLSSTINITEQKRREALLIDVARSLSTETGEAFFRSVVQHVAKAMEADL
VMVGETADDQSVTSLAMVQDGLLQPNIRYELAGTPCDMVIGHSDLCVYGDGVQQLFPQDGFLVDGGYRAYAGVALRDADG
TPIGIVNALWRKPQPLSPDRDALLQIFASRITAELMRLRRDREIARLNETLEQRVSERTDQLRATNAELESFGYSVSHDL
QSPLRSIEGFSVLLARRLRGRLSHEEQRLFDRVKANVVRMHELINDLLALARVSKGKLLLEQVNLSALAQQVIAQERQRE
PQRQVRVTVQPGISAHCDSKFARIILENLIGNAWKYSRAQADAQIEFGALPTREGGRKMLFVRDNGAGFNMAYSASLFKP
FHRLHHEHEFEGSGIGLATVHRILERHGGVIRAESTEGAGACFYFSFDPRFGPGAG

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=284, Percent_Identity=29.9295774647887, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=27.6422764227642, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=27.4881516587678, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI48994928, Length=256, Percent_Identity=25.390625, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 94608; Mature: 94477

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTSLPESAYLPARDLLEKRYIRGLRSVLLMLLLGLPLVLGLSVVQHSAGAQIAIVAVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LVLTGLAYWLLHRGHYPLASQLVVFSLIACSVAGILAYGSVRNALVLGFAGAVVTAGMTL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKRTLILSVALSAAALAALTWAEASGLLVKPDFGVGLRFWLILVLLLTGIAVSVYTSRQV
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLQALREQHTELKRREQAEYELLLSETRFSRIFRSSPAAIVVQAMNDMTVLDVNPAFERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCHHHHHH
YGYSRGEFIGSTDAALWDDPKARKAFLRQMEATDRVINLPLDGRRKDGQLINVLLSSEIE
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHCCCC
GRGPERIVVSTITDATAETQARQAARQSAELFSKAFDFSPINMTITRVSDGKFLAVNSAE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCHH
DLVQGFTASELIGRTSVDAGVWRDEEERKKFMEELRAQGQVQSHDRQMRHKDGTLIDCRM
HHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEHHHH
WAVIVEIAGEPCVLSSTINITEQKRREALLIDVARSLSTETGEAFFRSVVQHVAKAMEAD
HHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
LVMVGETADDQSVTSLAMVQDGLLQPNIRYELAGTPCDMVIGHSDLCVYGDGVQQLFPQD
EEEEECCCCCHHHHHHHHHHHCCCCCCCEEEECCCCHHEEECCCCEEEECCCHHHHCCCC
GFLVDGGYRAYAGVALRDADGTPIGIVNALWRKPQPLSPDRDALLQIFASRITAELMRLR
CEEECCCCEEEECEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RDREIARLNETLEQRVSERTDQLRATNAELESFGYSVSHDLQSPLRSIEGFSVLLARRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHH
GRLSHEEQRLFDRVKANVVRMHELINDLLALARVSKGKLLLEQVNLSALAQQVIAQERQR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
EPQRQVRVTVQPGISAHCDSKFARIILENLIGNAWKYSRAQADAQIEFGALPTREGGRKM
CCHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCCCEE
LFVRDNGAGFNMAYSASLFKPFHRLHHEHEFEGSGIGLATVHRILERHGGVIRAESTEGA
EEEECCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GACFYFSFDPRFGPGAG
CEEEEEEECCCCCCCCC
>Mature Secondary Structure 
PNTSLPESAYLPARDLLEKRYIRGLRSVLLMLLLGLPLVLGLSVVQHSAGAQIAIVAVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LVLTGLAYWLLHRGHYPLASQLVVFSLIACSVAGILAYGSVRNALVLGFAGAVVTAGMTL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKRTLILSVALSAAALAALTWAEASGLLVKPDFGVGLRFWLILVLLLTGIAVSVYTSRQV
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLQALREQHTELKRREQAEYELLLSETRFSRIFRSSPAAIVVQAMNDMTVLDVNPAFERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCHHHHHH
YGYSRGEFIGSTDAALWDDPKARKAFLRQMEATDRVINLPLDGRRKDGQLINVLLSSEIE
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHCCCC
GRGPERIVVSTITDATAETQARQAARQSAELFSKAFDFSPINMTITRVSDGKFLAVNSAE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCHH
DLVQGFTASELIGRTSVDAGVWRDEEERKKFMEELRAQGQVQSHDRQMRHKDGTLIDCRM
HHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEHHHH
WAVIVEIAGEPCVLSSTINITEQKRREALLIDVARSLSTETGEAFFRSVVQHVAKAMEAD
HHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
LVMVGETADDQSVTSLAMVQDGLLQPNIRYELAGTPCDMVIGHSDLCVYGDGVQQLFPQD
EEEEECCCCCHHHHHHHHHHHCCCCCCCEEEECCCCHHEEECCCCEEEECCCHHHHCCCC
GFLVDGGYRAYAGVALRDADGTPIGIVNALWRKPQPLSPDRDALLQIFASRITAELMRLR
CEEECCCCEEEECEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RDREIARLNETLEQRVSERTDQLRATNAELESFGYSVSHDLQSPLRSIEGFSVLLARRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHH
GRLSHEEQRLFDRVKANVVRMHELINDLLALARVSKGKLLLEQVNLSALAQQVIAQERQR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
EPQRQVRVTVQPGISAHCDSKFARIILENLIGNAWKYSRAQADAQIEFGALPTREGGRKM
CCHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCCCEE
LFVRDNGAGFNMAYSASLFKPFHRLHHEHEFEGSGIGLATVHRILERHGGVIRAESTEGA
EEEECCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GACFYFSFDPRFGPGAG
CEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]