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The map label for this gene is hisC1 [H]

Identifier: 91787578

GI number: 91787578

Start: 1745833

End: 1746903

Strand: Direct

Name: hisC1 [H]

Synonym: Bpro_1696

Alternate gene names: 91787578

Gene position: 1745833-1746903 (Clockwise)

Preceding gene: 91787577

Following gene: 91787582

Centisome position: 33.57

GC content: 57.52

Gene sequence:

>1071_bases
ATGAATTCTTCACAGTCTTTCTGGAGCCCGGTGGTCAGAGACCTGGTGCCGTACACGCCGGGTGAGCAGCCCAACATTGC
GGGCTTGATCAAGCTCAACACCAATGAAAACCCGTATCCGCCTTCTCCGGCTGCAGTGCGGGCTATCGCTGCCACGGCAC
AAGATGGCTTGCAGCTTTATCCCGATCCGCAAGCCACTTCGCTGCGTCAGGCCATCGCGGCGTACCACGGCATTGACGCT
GCGCAGGTGTTTCCAGGCAATGGGTCAGACGAGGTGCTTGCACACGCTTTTTTTGCGTTTTTCCAGCAAGATCAACCCAT
CCTGATGCCCGATATCACCTACAGTTTTTACAAGGTGTACTGTGGACTGTATGGCATTGCTTTCGAGGTCGTTCCCCTGG
ATGCTGCGATGCGCATTCAGGTGGCTGATTACCAGCGCGCTTGCGGCGGTGTGGTGATTGCGAACCCCAATGCGCCTACG
GGCACGGGATTGCCGCTGGCGCAGATTGAAAAGTTGTTGCAACAGCACAGCCGGCGGACAGTGCTTGTGGACGAGGCCTA
TGTGGACTTTGGTGGTGAGAGTGCCATCGGCCTGATTGATCGTTATCCCAATCTGCTGGTGGTGCACACTTTGTCGAAGT
CGCGCTCGCTGGCCGGTTTGCGGGTGGGGTTCGCCGCAGGGCAACGCCATTTAATAGAAGCGCTCGAACGTGTCAAAGAC
AGCTTCAACTCCTACCCGCTGGACCGTCTGGCGATTGCCGGTGCGGTGGCGGCCTACGAAGACAGGGCTCACTTTGAGAA
AACACGGGCAGCCGTGATGCAGAGTCGGGAGCTTTTGAGCAGGCAATTGCAGGCATTGGGCTTTGAGGTGTTACCGTCAC
AAGCCAATTTTCTGATGGCCCGCCATGGGCAGTATGACGCTGCGGCGCTGGCAGCCCGCCTGCGTGAAAAAGGCATTTTG
GCACGCCATTTCAAGCTGCCGCGCATTGAGCAATACCTCCGTATCAGCGTAGGCACTCCGTTGCAATGTGAGGCACTGGT
AGGCGCTTTGCGTGTACTGCTTGCCGCCTGA

Upstream 100 bases:

>100_bases
CATTGTTGGCCTGGTGTGGCGCTCCGTGGTGCTGTGGATGGTGCTGCTTGCCTTGTTGACGTTGGCGCGCCTGCTGGGCT
GAGCCGCGGATTCGAGTCGA

Downstream 100 bases:

>100_bases
CGTCGGGTTTTCAGTATCGGGTCTGCGACAACTCCGCAAACAATTCGCCATACAAACGATAGCGGTTTGGGCTGATGCTG
CTGGGCTTATCTGCCGAATT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNSSQSFWSPVVRDLVPYTPGEQPNIAGLIKLNTNENPYPPSPAAVRAIAATAQDGLQLYPDPQATSLRQAIAAYHGIDA
AQVFPGNGSDEVLAHAFFAFFQQDQPILMPDITYSFYKVYCGLYGIAFEVVPLDAAMRIQVADYQRACGGVVIANPNAPT
GTGLPLAQIEKLLQQHSRRTVLVDEAYVDFGGESAIGLIDRYPNLLVVHTLSKSRSLAGLRVGFAAGQRHLIEALERVKD
SFNSYPLDRLAIAGAVAAYEDRAHFEKTRAAVMQSRELLSRQLQALGFEVLPSQANFLMARHGQYDAAALAARLREKGIL
ARHFKLPRIEQYLRISVGTPLQCEALVGALRVLLAA

Sequences:

>Translated_356_residues
MNSSQSFWSPVVRDLVPYTPGEQPNIAGLIKLNTNENPYPPSPAAVRAIAATAQDGLQLYPDPQATSLRQAIAAYHGIDA
AQVFPGNGSDEVLAHAFFAFFQQDQPILMPDITYSFYKVYCGLYGIAFEVVPLDAAMRIQVADYQRACGGVVIANPNAPT
GTGLPLAQIEKLLQQHSRRTVLVDEAYVDFGGESAIGLIDRYPNLLVVHTLSKSRSLAGLRVGFAAGQRHLIEALERVKD
SFNSYPLDRLAIAGAVAAYEDRAHFEKTRAAVMQSRELLSRQLQALGFEVLPSQANFLMARHGQYDAAALAARLREKGIL
ARHFKLPRIEQYLRISVGTPLQCEALVGALRVLLAA
>Mature_356_residues
MNSSQSFWSPVVRDLVPYTPGEQPNIAGLIKLNTNENPYPPSPAAVRAIAATAQDGLQLYPDPQATSLRQAIAAYHGIDA
AQVFPGNGSDEVLAHAFFAFFQQDQPILMPDITYSFYKVYCGLYGIAFEVVPLDAAMRIQVADYQRACGGVVIANPNAPT
GTGLPLAQIEKLLQQHSRRTVLVDEAYVDFGGESAIGLIDRYPNLLVVHTLSKSRSLAGLRVGFAAGQRHLIEALERVKD
SFNSYPLDRLAIAGAVAAYEDRAHFEKTRAAVMQSRELLSRQLQALGFEVLPSQANFLMARHGQYDAAALAARLREKGIL
ARHFKLPRIEQYLRISVGTPLQCEALVGALRVLLAA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=351, Percent_Identity=29.0598290598291, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322075, Length=366, Percent_Identity=28.6885245901639, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38858; Mature: 38858

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSQSFWSPVVRDLVPYTPGEQPNIAGLIKLNTNENPYPPSPAAVRAIAATAQDGLQLY
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEC
PDPQATSLRQAIAAYHGIDAAQVFPGNGSDEVLAHAFFAFFQQDQPILMPDITYSFYKVY
CCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHH
CGLYGIAFEVVPLDAAMRIQVADYQRACGGVVIANPNAPTGTGLPLAQIEKLLQQHSRRT
HHHHHHHHEEEECCCEEEEEEHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCE
VLVDEAYVDFGGESAIGLIDRYPNLLVVHTLSKSRSLAGLRVGFAAGQRHLIEALERVKD
EEEEHHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
SFNSYPLDRLAIAGAVAAYEDRAHFEKTRAAVMQSRELLSRQLQALGFEVLPSQANFLMA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEH
RHGQYDAAALAARLREKGILARHFKLPRIEQYLRISVGTPLQCEALVGALRVLLAA
CCCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSSQSFWSPVVRDLVPYTPGEQPNIAGLIKLNTNENPYPPSPAAVRAIAATAQDGLQLY
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEC
PDPQATSLRQAIAAYHGIDAAQVFPGNGSDEVLAHAFFAFFQQDQPILMPDITYSFYKVY
CCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHH
CGLYGIAFEVVPLDAAMRIQVADYQRACGGVVIANPNAPTGTGLPLAQIEKLLQQHSRRT
HHHHHHHHEEEECCCEEEEEEHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCE
VLVDEAYVDFGGESAIGLIDRYPNLLVVHTLSKSRSLAGLRVGFAAGQRHLIEALERVKD
EEEEHHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
SFNSYPLDRLAIAGAVAAYEDRAHFEKTRAAVMQSRELLSRQLQALGFEVLPSQANFLMA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEH
RHGQYDAAALAARLREKGILARHFKLPRIEQYLRISVGTPLQCEALVGALRVLLAA
CCCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA