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The map label for this gene is fbp

Identifier: 91787471

GI number: 91787471

Start: 1635856

End: 1636863

Strand: Reverse

Name: fbp

Synonym: Bpro_1586

Alternate gene names: 91787471

Gene position: 1636863-1635856 (Counterclockwise)

Preceding gene: 91787472

Following gene: 91787470

Centisome position: 31.48

GC content: 60.81

Gene sequence:

>1008_bases
ATGTCTCAAAGAATTTCCCTCACCCGCTACCTGGTTGAGCAGCAACGCAGGGAAGGTCACATTCCTGCCCAGTTGCGGCT
GCTGCTTGAAGTGGTGGCCCGCGCCTGCAAAGGCATCAGCCAGTCCGTCAACAAAGGCGCACTGGGCGGCGTGCTCGGCA
CGGCCGGCAGTGAAAACGTGCAGGGCGAAGTCCAGAAAAAGCTCGACATCATCGCCAACGAAGTGCTGATCGAAGCCAAC
GAATGGGGTGGCCACCTGGCCGCCATGGCCTCGGAAGAAATGGACAGCATCTACCTGGTGCCCAACCGTTATCCGCAAGG
TGAATACCTGTTGCTGTTCGACCCGCTCGACGGCTCCAGCAACATCGACGTGAATGTCAGCATCGGCACCATCTTCAGCG
TGCTCAAAAAGCCCGACGACCATGCCGGCGTTGAAGAAAAAGACTTTTTGCAGCCGGGCAACAAACAGGTGGCCGCCGGC
TACTGCGTCTATGGCCCCCAAACCACGCTGGTGCTGACCGTGGGCGACGGCGTGGCCATGTTCACCCTCGACCGCGAGCA
GGGCTCCTTTGTGCTCATCGAGGAAAACGTGCGCATCCCCGAAGACACCAAGGAATTCGCCATCAACATGAGCAACATGC
GCCACTGGGATGCGCCGGTGAAGCGCTACATCGACGAATGCCTGCAGGGCACCGAAGGCCCGCGCGGCAAGGACTTCAAC
ATGCGTTGGGTTGCCTCCATGGTGGCCGACGTACACCGCATCCTGAGCCGCGGCGGCATCTTCATGTACCCCTGGGACAA
ACGCGAGCCCGAAAAGGCCGGCAAACTGCGCCTGATGTACGAAGCCAACCCCATGGGCTGGATCGTCGAGCAGGCCGGCG
GCTCCGCCACCAACGGCAAACAGCGCATTCTGGACATCCAGCCCGGCAAGCTGCACGAGCGGGTCAGCGTCATCCTCGGG
TCCAAAAATGAGGTAGAGCGGGTGACCGGCTACCACTCCGGGCTATAA

Upstream 100 bases:

>100_bases
CAAGACGGACCTGAGCAAGGACACGCTCGAAGTCGTCACGCGCGCACTGGCCGATTAACGGGACTAACGCGATTAACGTC
CCACACCACAGGAGTACACC

Downstream 100 bases:

>100_bases
TTGCGGGCTGTAATTCATACCACGCCGGTGTAGCTCAGTCGGTAGAGCAGCTCATTCGTAATGAGAAGGTCGGGTGTTCG
ATTCATCTCTCCGGCACCAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSQRISLTRYLVEQQRREGHIPAQLRLLLEVVARACKGISQSVNKGALGGVLGTAGSENVQGEVQKKLDIIANEVLIEAN
EWGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKPDDHAGVEEKDFLQPGNKQVAAG
YCVYGPQTTLVLTVGDGVAMFTLDREQGSFVLIEENVRIPEDTKEFAINMSNMRHWDAPVKRYIDECLQGTEGPRGKDFN
MRWVASMVADVHRILSRGGIFMYPWDKREPEKAGKLRLMYEANPMGWIVEQAGGSATNGKQRILDIQPGKLHERVSVILG
SKNEVERVTGYHSGL

Sequences:

>Translated_335_residues
MSQRISLTRYLVEQQRREGHIPAQLRLLLEVVARACKGISQSVNKGALGGVLGTAGSENVQGEVQKKLDIIANEVLIEAN
EWGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKPDDHAGVEEKDFLQPGNKQVAAG
YCVYGPQTTLVLTVGDGVAMFTLDREQGSFVLIEENVRIPEDTKEFAINMSNMRHWDAPVKRYIDECLQGTEGPRGKDFN
MRWVASMVADVHRILSRGGIFMYPWDKREPEKAGKLRLMYEANPMGWIVEQAGGSATNGKQRILDIQPGKLHERVSVILG
SKNEVERVTGYHSGL
>Mature_334_residues
SQRISLTRYLVEQQRREGHIPAQLRLLLEVVARACKGISQSVNKGALGGVLGTAGSENVQGEVQKKLDIIANEVLIEANE
WGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKPDDHAGVEEKDFLQPGNKQVAAGY
CVYGPQTTLVLTVGDGVAMFTLDREQGSFVLIEENVRIPEDTKEFAINMSNMRHWDAPVKRYIDECLQGTEGPRGKDFNM
RWVASMVADVHRILSRGGIFMYPWDKREPEKAGKLRLMYEANPMGWIVEQAGGSATNGKQRILDIQPGKLHERVSVILGS
KNEVERVTGYHSGL

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=323, Percent_Identity=42.1052631578947, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI189083692, Length=324, Percent_Identity=42.5925925925926, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI16579888, Length=324, Percent_Identity=42.5925925925926, Blast_Score=234, Evalue=1e-61,
Organism=Escherichia coli, GI1790679, Length=324, Percent_Identity=47.2222222222222, Blast_Score=281, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17508131, Length=330, Percent_Identity=43.6363636363636, Blast_Score=261, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6323409, Length=324, Percent_Identity=40.1234567901235, Blast_Score=255, Evalue=9e-69,
Organism=Drosophila melanogaster, GI45550998, Length=330, Percent_Identity=44.2424242424242, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI19921562, Length=330, Percent_Identity=44.2424242424242, Blast_Score=256, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_POLSJ (Q12D67)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_548423.1
- ProteinModelPortal:   Q12D67
- SMR:   Q12D67
- STRING:   Q12D67
- GeneID:   4015789
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1586
- NMPDR:   fig|296591.1.peg.179
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- PhylomeDB:   Q12D67
- ProtClustDB:   PRK09293
- BioCyc:   PSP296591:BPRO_1586-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 37141; Mature: 37010

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00124 FBPASE

Important sites: BINDING 209-209 BINDING 275-275

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRISLTRYLVEQQRREGHIPAQLRLLLEVVARACKGISQSVNKGALGGVLGTAGSENV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
QGEVQKKLDIIANEVLIEANEWGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSS
HHHHHHHHHHHHHHEEEEECCCCCEEEHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCC
NIDVNVSIGTIFSVLKKPDDHAGVEEKDFLQPGNKQVAAGYCVYGPQTTLVLTVGDGVAM
CEEEEEEHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCEEE
FTLDREQGSFVLIEENVRIPEDTKEFAINMSNMRHWDAPVKRYIDECLQGTEGPRGKDFN
EEEECCCCCEEEEECCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
MRWVASMVADVHRILSRGGIFMYPWDKREPEKAGKLRLMYEANPMGWIVEQAGGSATNGK
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCC
QRILDIQPGKLHERVSVILGSKNEVERVTGYHSGL
EEEEECCCCHHHHHHHEEECCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SQRISLTRYLVEQQRREGHIPAQLRLLLEVVARACKGISQSVNKGALGGVLGTAGSENV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
QGEVQKKLDIIANEVLIEANEWGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSS
HHHHHHHHHHHHHHEEEEECCCCCEEEHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCC
NIDVNVSIGTIFSVLKKPDDHAGVEEKDFLQPGNKQVAAGYCVYGPQTTLVLTVGDGVAM
CEEEEEEHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCEEE
FTLDREQGSFVLIEENVRIPEDTKEFAINMSNMRHWDAPVKRYIDECLQGTEGPRGKDFN
EEEECCCCCEEEEECCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
MRWVASMVADVHRILSRGGIFMYPWDKREPEKAGKLRLMYEANPMGWIVEQAGGSATNGK
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCC
QRILDIQPGKLHERVSVILGSKNEVERVTGYHSGL
EEEEECCCCHHHHHHHEEECCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA