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The map label for this gene is panD2

Identifier: 91787463

GI number: 91787463

Start: 1627201

End: 1627581

Strand: Direct

Name: panD2

Synonym: Bpro_1578

Alternate gene names: 91787463

Gene position: 1627201-1627581 (Clockwise)

Preceding gene: 91787462

Following gene: 91787464

Centisome position: 31.29

GC content: 59.58

Gene sequence:

>381_bases
ATGTTCCGAACCCTGCTCAAATCCAAGATCCACCGCGTCGCGGTAACCCACTGCGAGTTGCATTACGAAGGCTCCTGCGC
CATCGATGAAGACCTGCTCGACGCGGCCAACATCGCCGAGAACGAGCAAATCCATATCTGGAACATCAACAACGGCGAGC
GCTTTGTCACCTATGCGATCAAGGGGGAGCGCGGCTCCGGCATGATTTCGGTCAACGGCTCGGCCGCACGCCGCGCCGCT
GCCGGTGATCTGATCATCATCGCGGCCTTTGCCCAGGTGCACAACGACCAGGTGAGCGCACATGAACCCCAACTGGTGTT
TGTGGACGACAAGAACCGCCAGACCGAGTTGCGCCACAAGGTGCCAACCCAACGCATGTGA

Upstream 100 bases:

>100_bases
TTGATTTCAGCCCGCGCAGGCCGTTTCGAGCCAGGTCGTCTACAAGGCCTGATGCCCCATGACGTGACTGAAATTCCCCC
ATTGATTACAGAGACCCATC

Downstream 100 bases:

>100_bases
TGCCGCACCCCGGCGGCCTACCCGCCACCACCCTGGCCCAGCGCGTGCCGGCAACGCTGGACGATGTGCTGACCCAAACC
GCAGGCTTCTCCGATGCTGA

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase 2

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MFRTLLKSKIHRVAVTHCELHYEGSCAIDEDLLDAANIAENEQIHIWNINNGERFVTYAIKGERGSGMISVNGSAARRAA
AGDLIIIAAFAQVHNDQVSAHEPQLVFVDDKNRQTELRHKVPTQRM

Sequences:

>Translated_126_residues
MFRTLLKSKIHRVAVTHCELHYEGSCAIDEDLLDAANIAENEQIHIWNINNGERFVTYAIKGERGSGMISVNGSAARRAA
AGDLIIIAAFAQVHNDQVSAHEPQLVFVDDKNRQTELRHKVPTQRM
>Mature_126_residues
MFRTLLKSKIHRVAVTHCELHYEGSCAIDEDLLDAANIAENEQIHIWNINNGERFVTYAIKGERGSGMISVNGSAARRAA
AGDLIIIAAFAQVHNDQVSAHEPQLVFVDDKNRQTELRHKVPTQRM

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=124, Percent_Identity=51.6129032258064, Blast_Score=141, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND2_POLSJ (Q12D75)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_548415.1
- ProteinModelPortal:   Q12D75
- SMR:   Q12D75
- STRING:   Q12D75
- GeneID:   4015780
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1578
- NMPDR:   fig|296591.1.peg.171
- eggNOG:   COG0853
- HOGENOM:   HBG302821
- OMA:   VMNEQEV
- PhylomeDB:   Q12D75
- ProtClustDB:   PRK05449
- BioCyc:   PSP296591:BPRO_1578-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14105; Mature: 14105

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTLLKSKIHRVAVTHCELHYEGSCAIDEDLLDAANIAENEQIHIWNINNGERFVTYAI
CHHHHHHHHHHHEEEEEEEEEECCCCCCCHHHHHHCCCCCCCEEEEEECCCCCEEEEEEE
KGERGSGMISVNGSAARRAAAGDLIIIAAFAQVHNDQVSAHEPQLVFVDDKNRQTELRHK
ECCCCCEEEEECCCHHCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEECCCCCHHHHHC
VPTQRM
CCCCCC
>Mature Secondary Structure
MFRTLLKSKIHRVAVTHCELHYEGSCAIDEDLLDAANIAENEQIHIWNINNGERFVTYAI
CHHHHHHHHHHHEEEEEEEEEECCCCCCCHHHHHHCCCCCCCEEEEEECCCCCEEEEEEE
KGERGSGMISVNGSAARRAAAGDLIIIAAFAQVHNDQVSAHEPQLVFVDDKNRQTELRHK
ECCCCCEEEEECCCHHCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEECCCCCHHHHHC
VPTQRM
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA