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The map label for this gene is alsR [H]

Identifier: 91787373

GI number: 91787373

Start: 1531110

End: 1531979

Strand: Direct

Name: alsR [H]

Synonym: Bpro_1479

Alternate gene names: 91787373

Gene position: 1531110-1531979 (Clockwise)

Preceding gene: 91787368

Following gene: 91787376

Centisome position: 29.44

GC content: 64.83

Gene sequence:

>870_bases
ATGGACTTGCGCCAACTGTCCTACTTCGTGGCCGTGGCCGAAGAGCTGAGCTTTAGCCGCGCCGCCTCGCGCGTACACAT
TTCACAGCCGCCCCTGAGCCGCCAGATCGCCAAGCTCGAACAGGAACTGGGGGCGGTTTTGCTGATCCGTTCCTCGCATG
AGGTGGCCCTGACGCAGGCGGGCCAGGCGCTGCTGGAGGAAGCCCGCCGCCTGCTGGCGCTGGCGGCGGGCATTCCCGAG
GTCGTCGGCCGCGCCAGCCGCGGAGAAACCGGCTCGCTGCGCATCGGGTTTGTGGGCTCCACCATTTACACCTCGGTGCC
TGCCCTGTTAAGCCAATACCGGCAGATCTATCCGCATGTGGCGGTGTCCGTGCAGCAGCTCACGGTGGCCCGGCAAACCG
TCATGCTCAAAAACAGCGAGATCGACGTCGGCATCATTCGCCAGGCCGTCACCGAGCCCTGGCTGGCCACGCGCAGCCTG
TTCAAGGAAGGCTTCATGGCCGCGCTGCCGGTGCATCACCGGCTGGCGGGGCAGGACAGGGTCATGCTGCAGTCGCTGGC
GGAGGACGACTTCGTATTCTTCAGCCGCAGCGAGGCGCCGGCGATCCACGAACAGCTGCGCAAGATGTGCGAGGCCGCGG
GCTTTTCACCGCGCATCGTGCAAGAGGCCTACCCGATGTCGACCGTGGTGGGTCTGGTGGCGGCCGGCGTCGGGATTGCC
ATCGTCCCCGAGTCGATGCAAAGGCTGCAGATGCAGAATGTTTTATACCGGGCCCTGCGCGGGACCCGGGCGAAAACCGA
GTTCTTCCTGGCTTGGCATGTCGGCAACACGTCTCAAACCTTGCGGGGTTTCCTCGACATGAAGATGTGA

Upstream 100 bases:

>100_bases
TTTTGTCTCCAGAAGCAGTCGTTATGGAGTGGATGCTATGCCCCGCCTTTATTGCTGTCCAATGCATAATAAAGTCATTG
GCTATACCAGAAAGGTATTC

Downstream 100 bases:

>100_bases
GCAGGAATATCGGCAGGGCGGCCAAGCGCCGCCAGCACATGCTCGGGCGTGGCCGGTGCCTGCAGCACGACGGTCCGGTC
CGGCCGGACTGAAGCGATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDLRQLSYFVAVAEELSFSRAASRVHISQPPLSRQIAKLEQELGAVLLIRSSHEVALTQAGQALLEEARRLLALAAGIPE
VVGRASRGETGSLRIGFVGSTIYTSVPALLSQYRQIYPHVAVSVQQLTVARQTVMLKNSEIDVGIIRQAVTEPWLATRSL
FKEGFMAALPVHHRLAGQDRVMLQSLAEDDFVFFSRSEAPAIHEQLRKMCEAAGFSPRIVQEAYPMSTVVGLVAAGVGIA
IVPESMQRLQMQNVLYRALRGTRAKTEFFLAWHVGNTSQTLRGFLDMKM

Sequences:

>Translated_289_residues
MDLRQLSYFVAVAEELSFSRAASRVHISQPPLSRQIAKLEQELGAVLLIRSSHEVALTQAGQALLEEARRLLALAAGIPE
VVGRASRGETGSLRIGFVGSTIYTSVPALLSQYRQIYPHVAVSVQQLTVARQTVMLKNSEIDVGIIRQAVTEPWLATRSL
FKEGFMAALPVHHRLAGQDRVMLQSLAEDDFVFFSRSEAPAIHEQLRKMCEAAGFSPRIVQEAYPMSTVVGLVAAGVGIA
IVPESMQRLQMQNVLYRALRGTRAKTEFFLAWHVGNTSQTLRGFLDMKM
>Mature_289_residues
MDLRQLSYFVAVAEELSFSRAASRVHISQPPLSRQIAKLEQELGAVLLIRSSHEVALTQAGQALLEEARRLLALAAGIPE
VVGRASRGETGSLRIGFVGSTIYTSVPALLSQYRQIYPHVAVSVQQLTVARQTVMLKNSEIDVGIIRQAVTEPWLATRSL
FKEGFMAALPVHHRLAGQDRVMLQSLAEDDFVFFSRSEAPAIHEQLRKMCEAAGFSPRIVQEAYPMSTVVGLVAAGVGIA
IVPESMQRLQMQNVLYRALRGTRAKTEFFLAWHVGNTSQTLRGFLDMKM

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=273, Percent_Identity=36.6300366300366, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI2367136, Length=263, Percent_Identity=35.361216730038, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788887, Length=289, Percent_Identity=33.2179930795848, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI157672245, Length=230, Percent_Identity=34.3478260869565, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=29.6296296296296, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=28.5140562248996, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI145693105, Length=247, Percent_Identity=28.7449392712551, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=30.2040816326531, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787806, Length=249, Percent_Identity=27.3092369477912, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787530, Length=260, Percent_Identity=27.3076923076923, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790208, Length=280, Percent_Identity=26.4285714285714, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788296, Length=245, Percent_Identity=24.4897959183673, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=206, Percent_Identity=29.6116504854369, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=269, Percent_Identity=24.5353159851301, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786713, Length=297, Percent_Identity=26.5993265993266, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786401, Length=159, Percent_Identity=29.559748427673, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082132, Length=253, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31902; Mature: 31902

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRQLSYFVAVAEELSFSRAASRVHISQPPLSRQIAKLEQELGAVLLIRSSHEVALTQA
CCHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHH
GQALLEEARRLLALAAGIPEVVGRASRGETGSLRIGFVGSTIYTSVPALLSQYRQIYPHV
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHH
AVSVQQLTVARQTVMLKNSEIDVGIIRQAVTEPWLATRSLFKEGFMAALPVHHRLAGQDR
HHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCHHHHHHHHHHHCCHHHCCHHHHHCCCHH
VMLQSLAEDDFVFFSRSEAPAIHEQLRKMCEAAGFSPRIVQEAYPMSTVVGLVAAGVGIA
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCEE
IVPESMQRLQMQNVLYRALRGTRAKTEFFLAWHVGNTSQTLRGFLDMKM
ECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MDLRQLSYFVAVAEELSFSRAASRVHISQPPLSRQIAKLEQELGAVLLIRSSHEVALTQA
CCHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHH
GQALLEEARRLLALAAGIPEVVGRASRGETGSLRIGFVGSTIYTSVPALLSQYRQIYPHV
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHH
AVSVQQLTVARQTVMLKNSEIDVGIIRQAVTEPWLATRSLFKEGFMAALPVHHRLAGQDR
HHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCHHHHHHHHHHHCCHHHCCHHHHHCCCHH
VMLQSLAEDDFVFFSRSEAPAIHEQLRKMCEAAGFSPRIVQEAYPMSTVVGLVAAGVGIA
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCEE
IVPESMQRLQMQNVLYRALRGTRAKTEFFLAWHVGNTSQTLRGFLDMKM
ECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]