Click here to switch to the map view.

The map label for this gene is rtcR [H]

Identifier: 91787364

GI number: 91787364

Start: 1521037

End: 1522632

Strand: Reverse

Name: rtcR [H]

Synonym: Bpro_1470

Alternate gene names: 91787364

Gene position: 1522632-1521037 (Counterclockwise)

Preceding gene: 91787366

Following gene: 91787362

Centisome position: 29.28

GC content: 62.91

Gene sequence:

>1596_bases
ATGAAGAAGAAAGTGGTGATGGGTTTTCTGGGCACCCAGCTTGATTCGGGCCTGGGTTCGGCGCGCTGGGAGAAGTGGCG
GCCCACGGTGTCGATCGCGCAGCATGAAGACCTGATCGTCGACCGACTGGAGCTGATGCACGACCTGCGCAACAAGCCGC
TGGCCGAGCGGGTTCGTGACGACGTCGTTCAGCTCTCGCCCGGCACCGAGGTTCGCCTGAGCGAGATGAACCTGGCCAAT
CCCTGGGATTTCGGCGAGGTCTATGGCGCGCTGTATGACTGGGTCAGCGCTTACGCCTTCGACACCGAACGCGAAGAGTA
TTGGGCGCACATCACGACCGGCACCCACGTCGCGCAGATCTGCCTGTTTTTGCTGGTGGAGGCGCGCTTCATCCCCGGCG
TGCTGCTGCAAACGGCGCCGCCCAGGGGCCGGCAGGCCCAGGGCATCGGCAGCTATGAGCTGATTGATCTCGACCTCTCG
CGCTACGACGCGATCAACGCGCGGCTTGCGGTCGCGCAACAGGATGCCGTCTCCTTCCTCAAAAGCGGCATCGCCACACG
CAACCCGCGTTTCAACTCGCTGATCGAGGAAATAGAACGCATCGCCGTCCAGAGCAAAGCGCCCATTTTGCTGACCGGGC
CCACCGGCGCAGGCAAGTCCATGCTGGCACGGCGGATCTTTGAGCTCAAAAAGACGCGCCACCAGGTCAGCGGCAGCTTT
GTCGACGTGAACTGCGCGACCTTACACGGCGACGGCGCGGGCTCCACGCTGTTCGGCCACAAAAGGGGTTCGTTCACCGG
CGCGGCAAGCGACCGCCCCGGCCTGCTGCGCACCGCCGACAAGGGCGTGCTGTTTCTCGACGAGATCGGCGAACTGGGCC
TGGACGAACAGGCCATGCTGCTCAAGGCCGTCGAGGAAAAACGCTTCTTGCCCGTCGGCGCCGACCGGGAGGTCGACAGC
AGCTTCCAGTTGATCGCCGGCACCAATAAGGACTTGCGTTCGGAAGTCTCGCACGGGCGCTTCCGCGAAGACCTGTTCGC
GCGTATCAACCTGTGGACCTACACCATGCCCGGCCTCGGCCAGCGCCGGGAGGATATTGAACCCAATATGGACCACCAGC
TCATGCTGGCGTCCGAAGACCTTGGCCGGAAAACCCGCATGACCACCGAGGCACGCGCAGCGTACCTGCGATTTGCGCAG
TCAGGTGAAGCCATCTGGACCGGCAATTTCCGGGACCTGAGCGCATCGATCACGCGTCTTGCCACGCTGGGTGACAACGG
CCGTATCGGCGTGGGCCTGGTGGAGGCAGAGATAGCGCGGCTACGTTGGCAGTGGCAGGCCACGGCACAGGAAACCGGCG
GCATTGCCGTATCGCTTGCTGAATTGATGGGGAGCGCTGCGGACACGCTTGATTATTTTGAACAGCTGCAACTTCGGGCT
GTGATTGATGTCTGCCGAAGAAGCGCTTCCCTCAGCGATGCCGGGCGAGCGCTCTTCAATGTATCGCGCACCCAGCGCAG
CGTGGTGAACGACGCGGACCGGCTGCGCAAGTACTTGCTGAAGTTTGACCTGACCTGGGAGAAGCTGTCAGCCTGA

Upstream 100 bases:

>100_bases
TGATTTCATTGATTATTTTTACCATTCAATGCAAGCGATGAACCAAATCACCGCACTCATATTTCTCGATTTTTAGCTTT
GAAGCTAGTACATTAGAAAT

Downstream 100 bases:

>100_bases
TGCCTCTGCAGGAGCGCAACGCATGGCAACAAGGGTCGGACCGTCCGCTATTCACTCATCACCACCAACACCTGCGCATC
AGCGCGGCCCAGCGAGAGGT

Product: regulator of RNA terminal phosphate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MKKKVVMGFLGTQLDSGLGSARWEKWRPTVSIAQHEDLIVDRLELMHDLRNKPLAERVRDDVVQLSPGTEVRLSEMNLAN
PWDFGEVYGALYDWVSAYAFDTEREEYWAHITTGTHVAQICLFLLVEARFIPGVLLQTAPPRGRQAQGIGSYELIDLDLS
RYDAINARLAVAQQDAVSFLKSGIATRNPRFNSLIEEIERIAVQSKAPILLTGPTGAGKSMLARRIFELKKTRHQVSGSF
VDVNCATLHGDGAGSTLFGHKRGSFTGAASDRPGLLRTADKGVLFLDEIGELGLDEQAMLLKAVEEKRFLPVGADREVDS
SFQLIAGTNKDLRSEVSHGRFREDLFARINLWTYTMPGLGQRREDIEPNMDHQLMLASEDLGRKTRMTTEARAAYLRFAQ
SGEAIWTGNFRDLSASITRLATLGDNGRIGVGLVEAEIARLRWQWQATAQETGGIAVSLAELMGSAADTLDYFEQLQLRA
VIDVCRRSASLSDAGRALFNVSRTQRSVVNDADRLRKYLLKFDLTWEKLSA

Sequences:

>Translated_531_residues
MKKKVVMGFLGTQLDSGLGSARWEKWRPTVSIAQHEDLIVDRLELMHDLRNKPLAERVRDDVVQLSPGTEVRLSEMNLAN
PWDFGEVYGALYDWVSAYAFDTEREEYWAHITTGTHVAQICLFLLVEARFIPGVLLQTAPPRGRQAQGIGSYELIDLDLS
RYDAINARLAVAQQDAVSFLKSGIATRNPRFNSLIEEIERIAVQSKAPILLTGPTGAGKSMLARRIFELKKTRHQVSGSF
VDVNCATLHGDGAGSTLFGHKRGSFTGAASDRPGLLRTADKGVLFLDEIGELGLDEQAMLLKAVEEKRFLPVGADREVDS
SFQLIAGTNKDLRSEVSHGRFREDLFARINLWTYTMPGLGQRREDIEPNMDHQLMLASEDLGRKTRMTTEARAAYLRFAQ
SGEAIWTGNFRDLSASITRLATLGDNGRIGVGLVEAEIARLRWQWQATAQETGGIAVSLAELMGSAADTLDYFEQLQLRA
VIDVCRRSASLSDAGRALFNVSRTQRSVVNDADRLRKYLLKFDLTWEKLSA
>Mature_531_residues
MKKKVVMGFLGTQLDSGLGSARWEKWRPTVSIAQHEDLIVDRLELMHDLRNKPLAERVRDDVVQLSPGTEVRLSEMNLAN
PWDFGEVYGALYDWVSAYAFDTEREEYWAHITTGTHVAQICLFLLVEARFIPGVLLQTAPPRGRQAQGIGSYELIDLDLS
RYDAINARLAVAQQDAVSFLKSGIATRNPRFNSLIEEIERIAVQSKAPILLTGPTGAGKSMLARRIFELKKTRHQVSGSF
VDVNCATLHGDGAGSTLFGHKRGSFTGAASDRPGLLRTADKGVLFLDEIGELGLDEQAMLLKAVEEKRFLPVGADREVDS
SFQLIAGTNKDLRSEVSHGRFREDLFARINLWTYTMPGLGQRREDIEPNMDHQLMLASEDLGRKTRMTTEARAAYLRFAQ
SGEAIWTGNFRDLSASITRLATLGDNGRIGVGLVEAEIARLRWQWQATAQETGGIAVSLAELMGSAADTLDYFEQLQLRA
VIDVCRRSASLSDAGRALFNVSRTQRSVVNDADRLRKYLLKFDLTWEKLSA

Specific function: Transcriptional repressor of the rtcAB genes. Interacts with sigma-54 [H]

COG id: COG4650

COG function: function code KT; Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789828, Length=531, Percent_Identity=58.5687382297552, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI1788905, Length=292, Percent_Identity=33.9041095890411, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788550, Length=246, Percent_Identity=38.2113821138211, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789233, Length=233, Percent_Identity=36.0515021459227, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1790437, Length=253, Percent_Identity=35.1778656126482, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789087, Length=244, Percent_Identity=35.655737704918, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790299, Length=237, Percent_Identity=35.0210970464135, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87082152, Length=179, Percent_Identity=42.4581005586592, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI87082117, Length=292, Percent_Identity=31.8493150684932, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787583, Length=253, Percent_Identity=31.6205533596838, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786524, Length=229, Percent_Identity=34.4978165938865, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87081872, Length=239, Percent_Identity=32.6359832635983, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081858, Length=264, Percent_Identity=28.7878787878788, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078
- InterPro:   IPR009715
- InterPro:   IPR017183 [H]

Pfam domain/function: PF06956 RtcR; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59105; Mature: 59105

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50045 SIGMA54_INTERACT_4 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKVVMGFLGTQLDSGLGSARWEKWRPTVSIAQHEDLIVDRLELMHDLRNKPLAERVRD
CCCCEEEHHHHHHHHCCCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DVVQLSPGTEVRLSEMNLANPWDFGEVYGALYDWVSAYAFDTEREEYWAHITTGTHVAQI
HHEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCHHHHHH
CLFLLVEARFIPGVLLQTAPPRGRQAQGIGSYELIDLDLSRYDAINARLAVAQQDAVSFL
HHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
KSGIATRNPRFNSLIEEIERIAVQSKAPILLTGPTGAGKSMLARRIFELKKTRHQVSGSF
HHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCE
VDVNCATLHGDGAGSTLFGHKRGSFTGAASDRPGLLRTADKGVLFLDEIGELGLDEQAML
EEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEHHCCCCCCHHHHH
LKAVEEKRFLPVGADREVDSSFQLIAGTNKDLRSEVSHGRFREDLFARINLWTYTMPGLG
HHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHEEEEEEECCCCC
QRREDIEPNMDHQLMLASEDLGRKTRMTTEARAAYLRFAQSGEAIWTGNFRDLSASITRL
CCCCCCCCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHH
ATLGDNGRIGVGLVEAEIARLRWQWQATAQETGGIAVSLAELMGSAADTLDYFEQLQLRA
HCCCCCCCEEEEHHHHHHHHHHHEEEECHHHCCCCEEEHHHHHCCHHHHHHHHHHHHHHH
VIDVCRRSASLSDAGRALFNVSRTQRSVVNDADRLRKYLLKFDLTWEKLSA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MKKKVVMGFLGTQLDSGLGSARWEKWRPTVSIAQHEDLIVDRLELMHDLRNKPLAERVRD
CCCCEEEHHHHHHHHCCCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DVVQLSPGTEVRLSEMNLANPWDFGEVYGALYDWVSAYAFDTEREEYWAHITTGTHVAQI
HHEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCHHHHHH
CLFLLVEARFIPGVLLQTAPPRGRQAQGIGSYELIDLDLSRYDAINARLAVAQQDAVSFL
HHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
KSGIATRNPRFNSLIEEIERIAVQSKAPILLTGPTGAGKSMLARRIFELKKTRHQVSGSF
HHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCE
VDVNCATLHGDGAGSTLFGHKRGSFTGAASDRPGLLRTADKGVLFLDEIGELGLDEQAML
EEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEHHCCCCCCHHHHH
LKAVEEKRFLPVGADREVDSSFQLIAGTNKDLRSEVSHGRFREDLFARINLWTYTMPGLG
HHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHEEEEEEECCCCC
QRREDIEPNMDHQLMLASEDLGRKTRMTTEARAAYLRFAQSGEAIWTGNFRDLSASITRL
CCCCCCCCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHH
ATLGDNGRIGVGLVEAEIARLRWQWQATAQETGGIAVSLAELMGSAADTLDYFEQLQLRA
HCCCCCCCEEEEHHHHHHHHHHHEEEECHHHCCCCEEEHHHHHCCHHHHHHHHHHHHHHH
VIDVCRRSASLSDAGRALFNVSRTQRSVVNDADRLRKYLLKFDLTWEKLSA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3045764; 7984428; 7920643; 9738023 [H]