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The map label for this gene is dxs [C]

Identifier: 91787356

GI number: 91787356

Start: 1512353

End: 1513351

Strand: Direct

Name: dxs [C]

Synonym: Bpro_1462

Alternate gene names: 91787356

Gene position: 1512353-1513351 (Clockwise)

Preceding gene: 91787355

Following gene: 91787358

Centisome position: 29.08

GC content: 66.17

Gene sequence:

>999_bases
ATGAACACCGTGACAGAAAAGAAACCCCGCCTGACCACGTCCGCCATGATTGCGTCCATCGCGTCCGAGGGACAGCGCAC
CCGTGCAGCGCCGTTTGGCAAGGCGCTGGTGGAGCTGGCGGCCCAGCGCCCCGACATTGTGGGCATGACGGCTGACCTGG
CCAAGTACACCGACCTGCACCTGTTCGCCCAGGCGTGCCCGGAGCGGTTCTTCCAGATGGGCATGGCCGAGCAATTGCTG
ATGGGGGCCGCCGGCGGCATGGCCAAGGAAGGCTTTGTGCCCTTCGTCACCACCTATGCGGTATTTGCCACGCGGCGCGC
CTATGACTTCATGCACCAGGTGATCGCCGAGGAAAACCTGAATGTGAAAATCGTCTGCGCCCTGCCGGGCCTGACTACCG
GTTACGGCCCCAGCCACCAGGCCACCGAGGACCTGGCCGTGATGCGCGCCATGCCCGGCATGACGGTCATTGACCCCTGC
GATGCGCACGAGATTGAACAGGCCGTGCCCGCCATCGCCGCCCACGCGGGCCCGGTCTACATGCGCCTGCTGCGCGGGCA
GGTGCCGATGGTGCTGGACGAGTACGGCTACCGGTTTGAGCTGGGCAAGGCCAAGATGATCCGTGAGGGCCGTGACGTGC
TGTTTATCTCGACCGGCCTGATGACCATGCGTGCGCTGGAGGCCGCGCAGGCGCTGCAGCGTGACCAGGTCGATGCCGCA
GTGCTGCATGTGCCCACCCTCAAGCCGCTGGATGCGGCCACTATCCTGCGCGAGGCGGCCCGGGCCGGCCGTTTGGTGGT
GGTGGCAGAAAACCACAGCACCATCGGCGGCCTGGGCGAAGCCGTGGCCGGCGAGCTGATGCGTGCGGGCGTGCACCCTG
CGTTTCGCCAGATTGCCCTGCCCGATGCCTTCCTGGATGCGGGTGCACTGCCAACCTTGCATGACCGCTACGGCATTTCC
ACGGAGGCGGTGGTGGCCTCGGTGAAGTCCTGGCTGTAA

Upstream 100 bases:

>100_bases
TTCTGGAGCAGCGCGAAAAAAATCATTTCATCCGGGTCGACCCGCCTGAATGGCAGCAGGCCATCGCGATTCTTGACGCC
CAACATGCCGGAGCCAGCGA

Downstream 100 bases:

>100_bases
AAAGAAAACATGGCACACATGGGCTGGCGCCTGAGTGCGCCTGCCATGCTGCCAGCGCATTCCCGACTCAACATCCCCTC
CCAGGCGCTTGCCTGCGGCC

Product: transketolase subunit B

Products: D-ribose 5-phosphate; D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNTVTEKKPRLTTSAMIASIASEGQRTRAAPFGKALVELAAQRPDIVGMTADLAKYTDLHLFAQACPERFFQMGMAEQLL
MGAAGGMAKEGFVPFVTTYAVFATRRAYDFMHQVIAEENLNVKIVCALPGLTTGYGPSHQATEDLAVMRAMPGMTVIDPC
DAHEIEQAVPAIAAHAGPVYMRLLRGQVPMVLDEYGYRFELGKAKMIREGRDVLFISTGLMTMRALEAAQALQRDQVDAA
VLHVPTLKPLDAATILREAARAGRLVVVAENHSTIGGLGEAVAGELMRAGVHPAFRQIALPDAFLDAGALPTLHDRYGIS
TEAVVASVKSWL

Sequences:

>Translated_332_residues
MNTVTEKKPRLTTSAMIASIASEGQRTRAAPFGKALVELAAQRPDIVGMTADLAKYTDLHLFAQACPERFFQMGMAEQLL
MGAAGGMAKEGFVPFVTTYAVFATRRAYDFMHQVIAEENLNVKIVCALPGLTTGYGPSHQATEDLAVMRAMPGMTVIDPC
DAHEIEQAVPAIAAHAGPVYMRLLRGQVPMVLDEYGYRFELGKAKMIREGRDVLFISTGLMTMRALEAAQALQRDQVDAA
VLHVPTLKPLDAATILREAARAGRLVVVAENHSTIGGLGEAVAGELMRAGVHPAFRQIALPDAFLDAGALPTLHDRYGIS
TEAVVASVKSWL
>Mature_332_residues
MNTVTEKKPRLTTSAMIASIASEGQRTRAAPFGKALVELAAQRPDIVGMTADLAKYTDLHLFAQACPERFFQMGMAEQLL
MGAAGGMAKEGFVPFVTTYAVFATRRAYDFMHQVIAEENLNVKIVCALPGLTTGYGPSHQATEDLAVMRAMPGMTVIDPC
DAHEIEQAVPAIAAHAGPVYMRLLRGQVPMVLDEYGYRFELGKAKMIREGRDVLFISTGLMTMRALEAAQALQRDQVDAA
VLHVPTLKPLDAATILREAARAGRLVVVAENHSTIGGLGEAVAGELMRAGVHPAFRQIALPDAFLDAGALPTLHDRYGIS
TEAVVASVKSWL

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI225637463, Length=307, Percent_Identity=34.2019543973941, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI225637461, Length=307, Percent_Identity=34.2019543973941, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI225637459, Length=307, Percent_Identity=34.2019543973941, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI205277463, Length=262, Percent_Identity=34.3511450381679, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI4507521, Length=262, Percent_Identity=34.3511450381679, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI133778974, Length=304, Percent_Identity=31.9078947368421, Blast_Score=118, Evalue=8e-27,
Organism=Escherichia coli, GI1786622, Length=325, Percent_Identity=28.6153846153846, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17539652, Length=310, Percent_Identity=33.5483870967742, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45551847, Length=311, Percent_Identity=33.1189710610932, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45550715, Length=311, Percent_Identity=33.1189710610932, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666278, Length=301, Percent_Identity=31.5614617940199, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645119, Length=311, Percent_Identity=33.1189710610932, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: 2.2.1.1

Molecular weight: Translated: 35733; Mature: 35733

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVTEKKPRLTTSAMIASIASEGQRTRAAPFGKALVELAAQRPDIVGMTADLAKYTDLH
CCCCCCCCCCHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
LFAQACPERFFQMGMAEQLLMGAAGGMAKEGFVPFVTTYAVFATRRAYDFMHQVIAEENL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NVKIVCALPGLTTGYGPSHQATEDLAVMRAMPGMTVIDPCDAHEIEQAVPAIAAHAGPVY
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCHHH
MRLLRGQVPMVLDEYGYRFELGKAKMIREGRDVLFISTGLMTMRALEAAQALQRDQVDAA
HHHHHCCCCHHHHCCCCEEECCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
VLHVPTLKPLDAATILREAARAGRLVVVAENHSTIGGLGEAVAGELMRAGVHPAFRQIAL
EEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCC
PDAFLDAGALPTLHDRYGISTEAVVASVKSWL
CHHHHCCCCCCCHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNTVTEKKPRLTTSAMIASIASEGQRTRAAPFGKALVELAAQRPDIVGMTADLAKYTDLH
CCCCCCCCCCHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
LFAQACPERFFQMGMAEQLLMGAAGGMAKEGFVPFVTTYAVFATRRAYDFMHQVIAEENL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NVKIVCALPGLTTGYGPSHQATEDLAVMRAMPGMTVIDPCDAHEIEQAVPAIAAHAGPVY
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCHHH
MRLLRGQVPMVLDEYGYRFELGKAKMIREGRDVLFISTGLMTMRALEAAQALQRDQVDAA
HHHHHCCCCHHHHCCCCEEECCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
VLHVPTLKPLDAATILREAARAGRLVVVAENHSTIGGLGEAVAGELMRAGVHPAFRQIAL
EEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCC
PDAFLDAGALPTLHDRYGISTEAVVASVKSWL
CHHHHCCCCCCCHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sedoheptulose 7-phosphate; D-glyceraldehyde 3-phosphate

Specific reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]