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The map label for this gene is 91787107

Identifier: 91787107

GI number: 91787107

Start: 1253118

End: 1254479

Strand: Reverse

Name: 91787107

Synonym: Bpro_1210

Alternate gene names: NA

Gene position: 1254479-1253118 (Counterclockwise)

Preceding gene: 91787109

Following gene: 91787104

Centisome position: 24.12

GC content: 65.64

Gene sequence:

>1362_bases
ATGCGACTCCAGTTTCTCGGCGCTACGGACACGGTGACCGGCTCCAAGTACCTCGTGCAGCACGACAAGGCCAGGGTATT
GGTCGATTGCGGCCTGTTCCAGGGGTACAAACAGCTGCGCTTGCGCAACTGGTCGCCCTTGCCGGTGAAGCCGGCAGCGA
TTGACGCCGTGGTACTGACCCACGCCCACATCGACCACAGCGGCTACCTGCCGCTGCTGGCACGCCAGGGCTTTCGCGGC
AAGGTCTATTGCACGCCCGCCACCGCCGACCTGTGCCGCATCCTGCTGCCGGACTCCGGACACCTGCAGGAAGAGGAAGC
CGAATACGCCAACCGGCGCGGCCTGTCCAAGCATTCGCCCGCGCTGCCGCTGTACACGCGGGAAGATGCCGAACGCTGCC
TCAAGCTGCTCCACCCGGTCGATTACGGGAAACACTGGCAGCCGGCGCCGGGCTTGAACGCGAGCCTGACTCCGTCGGGC
CACATGCCGGGATCGTCGTTTGTGCGGCTGGACAATGGCTCGCGCTCGCTGCTGTTTTCAGGCGACATCGGTCGCCCGAA
CGACCTGGTGCTCAAGGCGCCGTCGCAGATGGACGGTGCGGACTACCTGGTCGTCGAATCCACCTACGGCGACCGCCTGC
ACAAATATTCCGATCCCCTGACGGTGCTAGGCGAAGTGATCAACCGAACCGCTGCGCGCGGCGGCGTGGTGGTGATCCCG
GCTTTCGCGGTCGGCCGGGCGCAGAGCCTGATGTACTGCATCCATCTGCTCAAGGCCCAGGGCGTGATTCATGACAACCT
GCCCGTCTACCTCAACAGCCCCATGGCCGCCAACGCCACCCAGGTGTTCCTCAAGCACAAGAGCGAGCTGCGGCTGACGG
CCGCGCAATGCAAGGCCATGACACACACGGCGCATATCGTGGGCACGCCGGAAGAGTCGCGCCTGCTCAATACCCGCAAG
GGCCCGATGGTCATCATCGCCGCCAGCGGCATGGCAACGGGCGGGCGCGTGGTGCATCACCTCAAGGCCTTCGCACCCGA
CCCGCGCAACACCATTTTGTTCGCCGGCTTCCAGGCCGGCGGCACGCGCGGCGCGATCATTGCCGGCGGTGCGCCCACCG
TACGCATCCATGGGGAAGACGTTCCGGTGCATGCCGAAGTGGCCATGCTCGACGACCTGTCGGCCCATGCCGACGCGGCC
GAGATCATCGGCTGGCTCAAGGGCTTCAAGGCGGCGCCGAAGAAGACCTTCATCACGCATGGCGAACCGCCAGCCGCCGA
TGCCATGCGCCAGCGCATCGAGCGCGAGCTGCACTGGACCTGCCACATGCCTTGCTACCTGGAAACGGTCGCCCTCAATT
GA

Upstream 100 bases:

>100_bases
CAAACCCTATTTTTTCGCTCCAGGGACTGCACTTGATCGAAATCAATCCACCCGTGGTACAACGGCCGGAAACTGATTCC
CTCCAACTGCCAGGATTTCC

Downstream 100 bases:

>100_bases
CCGTTGACCGGCTCCGGGCCGGCTCACGACCATTCAGGCTAGGCCCAATACGGTTCAGTTAAGCACCAAACTCCGTTCGG
GCTGAGCTGCCTGTCCTGAG

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLTHAHIDHSGYLPLLARQGFRG
KVYCTPATADLCRILLPDSGHLQEEEAEYANRRGLSKHSPALPLYTREDAERCLKLLHPVDYGKHWQPAPGLNASLTPSG
HMPGSSFVRLDNGSRSLLFSGDIGRPNDLVLKAPSQMDGADYLVVESTYGDRLHKYSDPLTVLGEVINRTAARGGVVVIP
AFAVGRAQSLMYCIHLLKAQGVIHDNLPVYLNSPMAANATQVFLKHKSELRLTAAQCKAMTHTAHIVGTPEESRLLNTRK
GPMVIIAASGMATGGRVVHHLKAFAPDPRNTILFAGFQAGGTRGAIIAGGAPTVRIHGEDVPVHAEVAMLDDLSAHADAA
EIIGWLKGFKAAPKKTFITHGEPPAADAMRQRIERELHWTCHMPCYLETVALN

Sequences:

>Translated_453_residues
MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLTHAHIDHSGYLPLLARQGFRG
KVYCTPATADLCRILLPDSGHLQEEEAEYANRRGLSKHSPALPLYTREDAERCLKLLHPVDYGKHWQPAPGLNASLTPSG
HMPGSSFVRLDNGSRSLLFSGDIGRPNDLVLKAPSQMDGADYLVVESTYGDRLHKYSDPLTVLGEVINRTAARGGVVVIP
AFAVGRAQSLMYCIHLLKAQGVIHDNLPVYLNSPMAANATQVFLKHKSELRLTAAQCKAMTHTAHIVGTPEESRLLNTRK
GPMVIIAASGMATGGRVVHHLKAFAPDPRNTILFAGFQAGGTRGAIIAGGAPTVRIHGEDVPVHAEVAMLDDLSAHADAA
EIIGWLKGFKAAPKKTFITHGEPPAADAMRQRIERELHWTCHMPCYLETVALN
>Mature_453_residues
MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLTHAHIDHSGYLPLLARQGFRG
KVYCTPATADLCRILLPDSGHLQEEEAEYANRRGLSKHSPALPLYTREDAERCLKLLHPVDYGKHWQPAPGLNASLTPSG
HMPGSSFVRLDNGSRSLLFSGDIGRPNDLVLKAPSQMDGADYLVVESTYGDRLHKYSDPLTVLGEVINRTAARGGVVVIP
AFAVGRAQSLMYCIHLLKAQGVIHDNLPVYLNSPMAANATQVFLKHKSELRLTAAQCKAMTHTAHIVGTPEESRLLNTRK
GPMVIIAASGMATGGRVVHHLKAFAPDPRNTILFAGFQAGGTRGAIIAGGAPTVRIHGEDVPVHAEVAMLDDLSAHADAA
EIIGWLKGFKAAPKKTFITHGEPPAADAMRQRIERELHWTCHMPCYLETVALN

Specific function: Has endoribonuclease activity towards 23S and 16S rRNA (in vitro) [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI33300633, Length=466, Percent_Identity=28.9699570815451, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI7706427, Length=465, Percent_Identity=25.1612903225806, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI32564696, Length=460, Percent_Identity=27.6086956521739, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI32566029, Length=448, Percent_Identity=26.1160714285714, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323307, Length=433, Percent_Identity=24.2494226327945, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21358523, Length=469, Percent_Identity=28.7846481876333, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24648013, Length=449, Percent_Identity=23.8307349665924, Blast_Score=138, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 49262; Mature: 49262

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLT
CEEEEECCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCCCCCCCHHHEEEEEE
HAHIDHSGYLPLLARQGFRGKVYCTPATADLCRILLPDSGHLQEEEAEYANRRGLSKHSP
EEEECCCCCCHHHHCCCCCCEEEECCCHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCCC
ALPLYTREDAERCLKLLHPVDYGKHWQPAPGLNASLTPSGHMPGSSFVRLDNGSRSLLFS
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEE
GDIGRPNDLVLKAPSQMDGADYLVVESTYGDRLHKYSDPLTVLGEVINRTAARGGVVVIP
CCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHHCCCCEEEEE
AFAVGRAQSLMYCIHLLKAQGVIHDNLPVYLNSPMAANATQVFLKHKSELRLTAAQCKAM
CHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCHHHHHHHCCCHHEEEHHHHHHH
THTAHIVGTPEESRLLNTRKGPMVIIAASGMATGGRVVHHLKAFAPDPRNTILFAGFQAG
HEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCC
GTRGAIIAGGAPTVRIHGEDVPVHAEVAMLDDLSAHADAAEIIGWLKGFKAAPKKTFITH
CCCCEEEECCCCEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEC
GEPPAADAMRQRIERELHWTCHMPCYLETVALN
CCCCHHHHHHHHHHHHHCEEECCCEEEEEEECC
>Mature Secondary Structure
MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLT
CEEEEECCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCCCCCCCHHHEEEEEE
HAHIDHSGYLPLLARQGFRGKVYCTPATADLCRILLPDSGHLQEEEAEYANRRGLSKHSP
EEEECCCCCCHHHHCCCCCCEEEECCCHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCCC
ALPLYTREDAERCLKLLHPVDYGKHWQPAPGLNASLTPSGHMPGSSFVRLDNGSRSLLFS
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEE
GDIGRPNDLVLKAPSQMDGADYLVVESTYGDRLHKYSDPLTVLGEVINRTAARGGVVVIP
CCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHHCCCCEEEEE
AFAVGRAQSLMYCIHLLKAQGVIHDNLPVYLNSPMAANATQVFLKHKSELRLTAAQCKAM
CHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCHHHHHHHCCCHHEEEHHHHHHH
THTAHIVGTPEESRLLNTRKGPMVIIAASGMATGGRVVHHLKAFAPDPRNTILFAGFQAG
HEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCC
GTRGAIIAGGAPTVRIHGEDVPVHAEVAMLDDLSAHADAAEIIGWLKGFKAAPKKTFITH
CCCCEEEECCCCEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEC
GEPPAADAMRQRIERELHWTCHMPCYLETVALN
CCCCHHHHHHHHHHHHHCEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA