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The map label for this gene is panC

Identifier: 91786797

GI number: 91786797

Start: 913113

End: 913961

Strand: Reverse

Name: panC

Synonym: Bpro_0895

Alternate gene names: 91786797

Gene position: 913961-913113 (Counterclockwise)

Preceding gene: 91786798

Following gene: 91786793

Centisome position: 17.58

GC content: 64.66

Gene sequence:

>849_bases
ATGCACATCGTTCACAGCATCGCCGAACTGCGCGAAAAACTGGCACCCTTCCAGCGCCCGGCCTTTGTGCCCACCATGGG
CAACCTGCATGACGGCCACATCGCGCTGGTCAAGCAGGCCAAGCCGCTGGGCGACGTGACGGTGTCCAGCATTTTTGTGA
ATCGCCTGCAGTTTGCGCCGCATGAGGATTTCGACAGCTACCCGCGCACGCTGGACGCCGATGCCCAGCGCCTGGAAGCC
GCAGGCTGCAATGTGCTGTTTGCGCCGCGCGAGAAAGAGCTGTACCCCGAGCCGCAGACCTACAAGATACACCCCGCCAC
CGACCTGGGCGACATCCTCGAGGGACACTTTCGCCCCGGCTTTTTCATCGGCGTCAGCACGGTGGTGCTCAAGCTTTTTT
CATGCGTCTATGCCGGCAAGCCGTCGGGCGTGGCCGCTTTCGGCAAAAAGGACTACCAGCAGGTGCTGGTGGTGCGCCGC
ATGGTGCAGCAGTTTGCCCTGCCAATCGAAATCCTGGCCGGTGAGACCCAGCGTGCGGCGGACGGGCTGGCGCTGTCATC
ACGCAACAGCTACCTGAGCCCCAACGAGCGCATTGAAGCGGCGCAACTGTCCAAAGCCCTGAAGGCGCTTGGCGATGCCG
CCCGGGCCACGCCAACGCCCGACCTGCTGGCGCTGGAAGCCCAGGCCATGCAGGCGCTGGCACGCCGCGGCTGGAAGCCC
GACTACCTGACCGTGCGCCGCCGCGCTGACCTGCAGCCACCGCAGGGGCCGCTGGCTTCAGAGCCGCTGGTGGTGCTGGG
TGCGGCCAAACTGGGCAACACCCGTCTGATTGACAACCTGGAAATTTGA

Upstream 100 bases:

>100_bases
GGCTTATGTCCGCGCCGTCAAAGACGGCAGCTTCCCGGTCAATGCCACCCACGCGTGGTAATCCGGACCCAGTCAAAAAA
AAAGCAGCCGAGGAGACCTC

Downstream 100 bases:

>100_bases
GCGGGCCGAGGCGGGGAGCGGAGCGGCACCCCGATTCGCTCTACTGTTGCGTGTCAGCGGTGTCAGCGTCTGCAGGCTGC
TCCGGGGACGACTCTGCAGG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MHIVHSIAELREKLAPFQRPAFVPTMGNLHDGHIALVKQAKPLGDVTVSSIFVNRLQFAPHEDFDSYPRTLDADAQRLEA
AGCNVLFAPREKELYPEPQTYKIHPATDLGDILEGHFRPGFFIGVSTVVLKLFSCVYAGKPSGVAAFGKKDYQQVLVVRR
MVQQFALPIEILAGETQRAADGLALSSRNSYLSPNERIEAAQLSKALKALGDAARATPTPDLLALEAQAMQALARRGWKP
DYLTVRRRADLQPPQGPLASEPLVVLGAAKLGNTRLIDNLEI

Sequences:

>Translated_282_residues
MHIVHSIAELREKLAPFQRPAFVPTMGNLHDGHIALVKQAKPLGDVTVSSIFVNRLQFAPHEDFDSYPRTLDADAQRLEA
AGCNVLFAPREKELYPEPQTYKIHPATDLGDILEGHFRPGFFIGVSTVVLKLFSCVYAGKPSGVAAFGKKDYQQVLVVRR
MVQQFALPIEILAGETQRAADGLALSSRNSYLSPNERIEAAQLSKALKALGDAARATPTPDLLALEAQAMQALARRGWKP
DYLTVRRRADLQPPQGPLASEPLVVLGAAKLGNTRLIDNLEI
>Mature_282_residues
MHIVHSIAELREKLAPFQRPAFVPTMGNLHDGHIALVKQAKPLGDVTVSSIFVNRLQFAPHEDFDSYPRTLDADAQRLEA
AGCNVLFAPREKELYPEPQTYKIHPATDLGDILEGHFRPGFFIGVSTVVLKLFSCVYAGKPSGVAAFGKKDYQQVLVVRR
MVQQFALPIEILAGETQRAADGLALSSRNSYLSPNERIEAAQLSKALKALGDAARATPTPDLLALEAQAMQALARRGWKP
DYLTVRRRADLQPPQGPLASEPLVVLGAAKLGNTRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=286, Percent_Identity=43.006993006993, Blast_Score=194, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6322046, Length=316, Percent_Identity=35.4430379746835, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_POLSJ (Q12F41)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547749.1
- STRING:   Q12F41
- GeneID:   4011203
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_0895
- NMPDR:   fig|296591.1.peg.3037
- eggNOG:   COG0414
- HOGENOM:   HBG428839
- OMA:   RLIDNFT
- PhylomeDB:   Q12F41
- ProtClustDB:   PRK00380
- BioCyc:   PSP296591:BPRO_0895-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 30893; Mature: 30893

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: ACT_SITE 33-33 BINDING 57-57 BINDING 57-57 BINDING 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIVHSIAELREKLAPFQRPAFVPTMGNLHDGHIALVKQAKPLGDVTVSSIFVNRLQFAP
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
HEDFDSYPRTLDADAQRLEAAGCNVLFAPREKELYPEPQTYKIHPATDLGDILEGHFRPG
CCCHHHCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCC
FFIGVSTVVLKLFSCVYAGKPSGVAAFGKKDYQQVLVVRRMVQQFALPIEILAGETQRAA
HHHHHHHHHHHHHHHHHCCCCCCEEHHCHHHHHHHHHHHHHHHHHCCCHHEECCCCHHHH
DGLALSSRNSYLSPNERIEAAQLSKALKALGDAARATPTPDLLALEAQAMQALARRGWKP
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
DYLTVRRRADLQPPQGPLASEPLVVLGAAKLGNTRLIDNLEI
CCEEHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MHIVHSIAELREKLAPFQRPAFVPTMGNLHDGHIALVKQAKPLGDVTVSSIFVNRLQFAP
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
HEDFDSYPRTLDADAQRLEAAGCNVLFAPREKELYPEPQTYKIHPATDLGDILEGHFRPG
CCCHHHCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCC
FFIGVSTVVLKLFSCVYAGKPSGVAAFGKKDYQQVLVVRRMVQQFALPIEILAGETQRAA
HHHHHHHHHHHHHHHHHCCCCCCEEHHCHHHHHHHHHHHHHHHHHCCCHHEECCCCHHHH
DGLALSSRNSYLSPNERIEAAQLSKALKALGDAARATPTPDLLALEAQAMQALARRGWKP
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
DYLTVRRRADLQPPQGPLASEPLVVLGAAKLGNTRLIDNLEI
CCEEHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA