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The map label for this gene is gpmA [H]

Identifier: 91786788

GI number: 91786788

Start: 907697

End: 908578

Strand: Reverse

Name: gpmA [H]

Synonym: Bpro_0886

Alternate gene names: 91786788

Gene position: 908578-907697 (Counterclockwise)

Preceding gene: 91786793

Following gene: 91786787

Centisome position: 17.47

GC content: 62.7

Gene sequence:

>882_bases
GTGTTTTTCACCAAACCAGTGATTTTAGAATGGAGGCCGGAAATTGCCTACCGGCTGCCTCTTTTACCCCTGCCTGCTGC
ACCCTTTCTCACCCCCGTTTTCACTTCATCCCTCTCCTTCCCACCCGACTGCCACACCATGTACAAACTCGTACTCATCC
GCCATGGCGAATCCACCTGGAACCTTGAAAACCGATTTACCGGCTGGACCGATGTCGACCTGACGGAAACCGGCATCCAG
CAAGCCAAGGATGCCGGAAAGCTGCTCAAGGCCGAGGGTTACGACTTTGACCTGGCCTACACCAGCGTGCTCAAGCGCGC
CACCCGCACCCTCTGGCATGTGCTGGACGAGATGGACCGGACCTGGCTGCCGGTCGTGAACAGCTGGCGGCTGAACGAGC
GCCATTACGGCGCGCTGCAGGGCCTGAACAAGGCCGAGACAGCCAAAAAATATGGCGAAGACCAGGTACTGATCTGGCGC
CGCAGCTATGACACGCCGCCCCCGCCGCTGGCGGCCAACGACGAGCGCTGCGAACGCGGCGACCCCCGCTATGCCAAGCT
GCCGCCCGAGCAGGTGCCGCTGACGGAGTGCCTGAAAGACACGGTGGCGCGGGTGTTGCCCTTCTGGAATGAGTCCATGG
CACCCGCCATCAAGGCCGGCAAGCGCGTGGTGGTGGCTGCCCACGGCAACTCGATACGCGCGCTGGTGAAGTACCTGGAC
AACATCTCCGACAGCGACATCGTGGGACTCAACATCCCCAACGGCATTCCGCTGGTGTATGAGCTGGATGCCCAGCTCAG
GCCCCTGCGCCACTACTACCTGGGCGACAGCGAAGCCGCTGCCAGGGCCGTGGCGGCCGTCAGCGCCCAGGGCAAGGCCT
GA

Upstream 100 bases:

>100_bases
ACACCGGAAATCATGGGCCAGATCAGCATGCCGCCCGAGGCGAGCGCTACCGAAATCAGCATCCAGTTATCGATCAGAAA
TTTCACTTGCTACCCTTTGT

Downstream 100 bases:

>100_bases
ACACGGCCTTTCGGACCTGATGGACCTGCTTTTTTGTAAAGGTCCTGTAAAACCCGACGGTTCCGGTACTTTTACGGCTT
CCCGGCTGCGTCCTTGGGGG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MFFTKPVILEWRPEIAYRLPLLPLPAAPFLTPVFTSSLSFPPDCHTMYKLVLIRHGESTWNLENRFTGWTDVDLTETGIQ
QAKDAGKLLKAEGYDFDLAYTSVLKRATRTLWHVLDEMDRTWLPVVNSWRLNERHYGALQGLNKAETAKKYGEDQVLIWR
RSYDTPPPPLAANDERCERGDPRYAKLPPEQVPLTECLKDTVARVLPFWNESMAPAIKAGKRVVVAAHGNSIRALVKYLD
NISDSDIVGLNIPNGIPLVYELDAQLRPLRHYYLGDSEAAARAVAAVSAQGKA

Sequences:

>Translated_293_residues
MFFTKPVILEWRPEIAYRLPLLPLPAAPFLTPVFTSSLSFPPDCHTMYKLVLIRHGESTWNLENRFTGWTDVDLTETGIQ
QAKDAGKLLKAEGYDFDLAYTSVLKRATRTLWHVLDEMDRTWLPVVNSWRLNERHYGALQGLNKAETAKKYGEDQVLIWR
RSYDTPPPPLAANDERCERGDPRYAKLPPEQVPLTECLKDTVARVLPFWNESMAPAIKAGKRVVVAAHGNSIRALVKYLD
NISDSDIVGLNIPNGIPLVYELDAQLRPLRHYYLGDSEAAARAVAAVSAQGKA
>Mature_293_residues
MFFTKPVILEWRPEIAYRLPLLPLPAAPFLTPVFTSSLSFPPDCHTMYKLVLIRHGESTWNLENRFTGWTDVDLTETGIQ
QAKDAGKLLKAEGYDFDLAYTSVLKRATRTLWHVLDEMDRTWLPVVNSWRLNERHYGALQGLNKAETAKKYGEDQVLIWR
RSYDTPPPPLAANDERCERGDPRYAKLPPEQVPLTECLKDTVARVLPFWNESMAPAIKAGKRVVVAAHGNSIRALVKYLD
NISDSDIVGLNIPNGIPLVYELDAQLRPLRHYYLGDSEAAARAVAAVSAQGKA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=252, Percent_Identity=57.9365079365079, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=59.8393574297189, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=57.8313253012048, Blast_Score=287, Evalue=7e-78,
Organism=Homo sapiens, GI4502445, Length=253, Percent_Identity=47.4308300395257, Blast_Score=260, Evalue=9e-70,
Organism=Homo sapiens, GI40353764, Length=253, Percent_Identity=47.4308300395257, Blast_Score=260, Evalue=9e-70,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.3456790123457, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1786970, Length=245, Percent_Identity=64.4897959183673, Blast_Score=335, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=52.8455284552846, Blast_Score=248, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6324516, Length=294, Percent_Identity=35.3741496598639, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320183, Length=307, Percent_Identity=31.9218241042345, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324857, Length=198, Percent_Identity=25.2525252525253, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=54.8, Blast_Score=280, Evalue=6e-76,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=53.6, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=53.6, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=53.6, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=39.8406374501992, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=39.8406374501992, Blast_Score=180, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=39.8406374501992, Blast_Score=180, Evalue=1e-45,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 33026; Mature: 33026

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFTKPVILEWRPEIAYRLPLLPLPAAPFLTPVFTSSLSFPPDCHTMYKLVLIRHGESTW
CCCCCCEEEEECCCHHEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHEECCCCCC
NLENRFTGWTDVDLTETGIQQAKDAGKLLKAEGYDFDLAYTSVLKRATRTLWHVLDEMDR
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TWLPVVNSWRLNERHYGALQGLNKAETAKKYGEDQVLIWRRSYDTPPPPLAANDERCERG
CCCCCCCCEECCCHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHCC
DPRYAKLPPEQVPLTECLKDTVARVLPFWNESMAPAIKAGKRVVVAAHGNSIRALVKYLD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHH
NISDSDIVGLNIPNGIPLVYELDAQLRPLRHYYLGDSEAAARAVAAVSAQGKA
CCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFFTKPVILEWRPEIAYRLPLLPLPAAPFLTPVFTSSLSFPPDCHTMYKLVLIRHGESTW
CCCCCCEEEEECCCHHEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHEECCCCCC
NLENRFTGWTDVDLTETGIQQAKDAGKLLKAEGYDFDLAYTSVLKRATRTLWHVLDEMDR
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TWLPVVNSWRLNERHYGALQGLNKAETAKKYGEDQVLIWRRSYDTPPPPLAANDERCERG
CCCCCCCCEECCCHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHCC
DPRYAKLPPEQVPLTECLKDTVARVLPFWNESMAPAIKAGKRVVVAAHGNSIRALVKYLD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHH
NISDSDIVGLNIPNGIPLVYELDAQLRPLRHYYLGDSEAAARAVAAVSAQGKA
CCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA