Click here to switch to the map view.

The map label for this gene is moeB [H]

Identifier: 91786786

GI number: 91786786

Start: 905161

End: 905940

Strand: Reverse

Name: moeB [H]

Synonym: Bpro_0884

Alternate gene names: 91786786

Gene position: 905940-905161 (Counterclockwise)

Preceding gene: 91786787

Following gene: 91786784

Centisome position: 17.42

GC content: 64.1

Gene sequence:

>780_bases
ATGAACGACGAACAGCTGCTCCGCTATTCCCGGCACATCCTGCTCGACGAACTGGGTATTGAGGGCCAGGAAAAGCTCCT
GTCCTCGCGCGTGCTGATTGTGGGCGCGGGCGGCCTGGGTTCTCCGGTGGCCCTGTACCTCGGCAGTGCCGGCGTGGGCC
GCATCACCGTTGTCGACCATGACCGCGTGGATGCCACCAACCTGCAGCGGCAGATTGCCCACAACCTGGCCCGCATCGGT
ACGTTCAAGGCAGAGTCCGTGGTGCAGTCCGTGGCGGCCATCAACCCGGATGTCCAGGTCATCCCGGTCACGCAGCGGGC
CGAGGGTGCGCTGCTTGACGAACTGGTCCGGGAGGCTGACCTGGTTCTCGACTGCACCGACAACTTTGCCACCCGCCATG
CCATTAACCGTGCATGTGTCAGGCACAGCAAGCCTCTGGTCTCCGGCGCGGCTATCCGCTTTGACGGCCAGGTGTCGGTC
TATGACCCGCGGAGCGCGCAATCGCCCTGCTATGCCTGCGTGTTTCCGGAGTCGGATTTGTTCGAAGAAACCCGCTGCGC
CACCATGGGTGTGTTTGCCCCCCTGGTCGGCATCGTGGGGACCGTGCAGGCCGCCGAAGCCTTGAAGCTGCTCTGCGGCG
TCGGGCAGCCACTGACCGGGCGGCTGCTGATGCTGGATGGCCGAACCATGGAGTGGAGCGAAATGAAACTGGCGCGAAAC
ATCGCCTGCACGGTCTGTGGTGCCTCCGCTCCCACGCCTACACCTACTACCACTGATTGA

Upstream 100 bases:

>100_bases
TAACGATCAGGTCGTCGGCTCCCGTCCACCTGATCGGATCCACCCGTGCGCTGCCCCTGCGCCGACGCGGGTACGTACCG
GCTTATGTCCCCTTTCTCCC

Downstream 100 bases:

>100_bases
GCCGGGGGGCCTCGAGAACCGGTCCCTGCGCCCAGGGTCACCCGCCACTCACCGGGTGGCCGTCGCAGCAGGTCTGGAGC
CCCCATTAGGCTTGGCGGCC

Product: UBA/THIF-type NAD/FAD-binding fold

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNDEQLLRYSRHILLDELGIEGQEKLLSSRVLIVGAGGLGSPVALYLGSAGVGRITVVDHDRVDATNLQRQIAHNLARIG
TFKAESVVQSVAAINPDVQVIPVTQRAEGALLDELVREADLVLDCTDNFATRHAINRACVRHSKPLVSGAAIRFDGQVSV
YDPRSAQSPCYACVFPESDLFEETRCATMGVFAPLVGIVGTVQAAEALKLLCGVGQPLTGRLLMLDGRTMEWSEMKLARN
IACTVCGASAPTPTPTTTD

Sequences:

>Translated_259_residues
MNDEQLLRYSRHILLDELGIEGQEKLLSSRVLIVGAGGLGSPVALYLGSAGVGRITVVDHDRVDATNLQRQIAHNLARIG
TFKAESVVQSVAAINPDVQVIPVTQRAEGALLDELVREADLVLDCTDNFATRHAINRACVRHSKPLVSGAAIRFDGQVSV
YDPRSAQSPCYACVFPESDLFEETRCATMGVFAPLVGIVGTVQAAEALKLLCGVGQPLTGRLLMLDGRTMEWSEMKLARN
IACTVCGASAPTPTPTTTD
>Mature_259_residues
MNDEQLLRYSRHILLDELGIEGQEKLLSSRVLIVGAGGLGSPVALYLGSAGVGRITVVDHDRVDATNLQRQIAHNLARIG
TFKAESVVQSVAAINPDVQVIPVTQRAEGALLDELVREADLVLDCTDNFATRHAINRACVRHSKPLVSGAAIRFDGQVSV
YDPRSAQSPCYACVFPESDLFEETRCATMGVFAPLVGIVGTVQAAEALKLLCGVGQPLTGRLLMLDGRTMEWSEMKLARN
IACTVCGASAPTPTPTTTD

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=261, Percent_Identity=42.911877394636, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI4885649, Length=151, Percent_Identity=29.8013245033113, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI38045948, Length=166, Percent_Identity=31.3253012048193, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787048, Length=249, Percent_Identity=46.9879518072289, Blast_Score=228, Evalue=2e-61,
Organism=Escherichia coli, GI87082356, Length=253, Percent_Identity=46.2450592885375, Blast_Score=210, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17540406, Length=266, Percent_Identity=40.9774436090226, Blast_Score=205, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193203301, Length=155, Percent_Identity=30.9677419354839, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86565431, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86565433, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=253, Percent_Identity=33.596837944664, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6322639, Length=172, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320598, Length=167, Percent_Identity=28.7425149700599, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582879, Length=250, Percent_Identity=40.8, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24660640, Length=156, Percent_Identity=32.6923076923077, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: 2.7.7.-

Molecular weight: Translated: 27697; Mature: 27697

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDEQLLRYSRHILLDELGIEGQEKLLSSRVLIVGAGGLGSPVALYLGSAGVGRITVVDH
CCHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCEEEECCCCCCEEEEEEC
DRVDATNLQRQIAHNLARIGTFKAESVVQSVAAINPDVQVIPVTQRAEGALLDELVREAD
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC
LVLDCTDNFATRHAINRACVRHSKPLVSGAAIRFDGQVSVYDPRSAQSPCYACVFPESDL
EEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCCCEEEEECCCHHH
FEETRCATMGVFAPLVGIVGTVQAAEALKLLCGVGQPLTGRLLMLDGRTMEWSEMKLARN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHH
IACTVCGASAPTPTPTTTD
HEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNDEQLLRYSRHILLDELGIEGQEKLLSSRVLIVGAGGLGSPVALYLGSAGVGRITVVDH
CCHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCEEEECCCCCCEEEEEEC
DRVDATNLQRQIAHNLARIGTFKAESVVQSVAAINPDVQVIPVTQRAEGALLDELVREAD
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC
LVLDCTDNFATRHAINRACVRHSKPLVSGAAIRFDGQVSVYDPRSAQSPCYACVFPESDL
EEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCCCEEEEECCCHHH
FEETRCATMGVFAPLVGIVGTVQAAEALKLLCGVGQPLTGRLLMLDGRTMEWSEMKLARN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHH
IACTVCGASAPTPTPTTTD
HEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]