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The map label for this gene is degP [H]

Identifier: 91786719

GI number: 91786719

Start: 839348

End: 840502

Strand: Reverse

Name: degP [H]

Synonym: Bpro_0817

Alternate gene names: 91786719

Gene position: 840502-839348 (Counterclockwise)

Preceding gene: 91786722

Following gene: 91786682

Centisome position: 16.16

GC content: 64.59

Gene sequence:

>1155_bases
ATGAAGCGCACCTGGCTCCTGTTTTCCCAGACCGTCACTGTTCTGGTGGCCGCCTATTTTGTCGTGGCAACGCTCCAGCC
GCAGTGGCTGGGGACCTCGTCGATCGGCGGGGTTTCCGTGATCGAAGCACCGGCCAGCAGCGTGCAACTCGGTCCAAGAC
CGGCCGGCACCTTCAGTTCGGCCGCGAAAATCGCCTCGGCGGCGGTGGTCAGCATCAACACCAGCAAGGCCGCCGTCAAT
AACCCGCATGCCGACGATCCGTGGTTCAAGTTTTTCTTCGGCGACCAGGGCCGCAGCGAACCCCAGGGCGGCCTGGGCAG
CGGGGTCATCATCAGCGCCACCGGCTATATCCTGACCAACAACCATGTGGTCGAAGGCGCTGACGAGATCGAGGTCATCC
TCAACGATACGCGCAAGGCCAAGGCCCAGGTGATAGGCACCGACCCCGACACCGACCTGGCCATTCTCAAGATCAACCTG
GACAAGCTGCCCGTCATTGTCCTGGGCAACTCCGACGCACTGCAAATAGGCGACCCGGTGCTGGCCATAGGCAACCCTTT
CGGCGTGGGCCAGACCGTGACGGGTGGCATCGTGAGCGCACTCGGGCGCAACCAGCTCGGCATCAACACCTTCGAGAACT
TCATCCAGACCGATGCGGCCATCAACCCCGGCAATTCAGGCGGGGCGCTGGTCGACGTGAACGGCCACCTGATGGGCATC
AACACCGCCATTTACTCGCGCTCGGGCGGCTCCATGGGCATCGGCTTTGCCATCCCGGTGTCCACGGCCAAGCAGGTGCT
TGAGGGGATCGTGAAAGACGGGCAGGTCACGCGCGGCTGGATTGGCGTGGAACCGCAGGAGCTCAATGCCGAACTGGCTG
AGACCTTCAATATCAAGCCCGCGGCGCTGAAGGATGGCGGCGTGATCATCATCGGCGTGCTGCAAAACGGCCCGGCCGCG
CAGGCGGGCATCCAGCCCGGCGACGTGATCACCGCGGTCAACGGCAAGTCCGTGAGCAATGTGAGCCAACTGCTGACCGC
CGTAGCCGCGCTGAAGCCCGGCACGCCGGCCCCCCTGACCGTATGGCGCCGGGATCGCCAGACCGACATTGCGGTCACAC
CCGGCAAGCGCCAGCGGCCCAGGGTGCAGCGCTGA

Upstream 100 bases:

>100_bases
TTGAGGGACAATATGGTTGATGCAGCGCCCACTTGCCCCGGTCTGCAAATAATTTGGCCTTGACACACTCCGCTCACTAC
CCCCAACCCCCTTTGTACCC

Downstream 100 bases:

>100_bases
GGGGATCAATGCGCCGGGGTTGGCGGGGGCCGGCGCGCAACCTCAGGGCTTGGCCGCTTCCGTTTCGCTGTCGGTATCGG
GGGCCTTGGTGTGCTTGACA

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKRTWLLFSQTVTVLVAAYFVVATLQPQWLGTSSIGGVSVIEAPASSVQLGPRPAGTFSSAAKIASAAVVSINTSKAAVN
NPHADDPWFKFFFGDQGRSEPQGGLGSGVIISATGYILTNNHVVEGADEIEVILNDTRKAKAQVIGTDPDTDLAILKINL
DKLPVIVLGNSDALQIGDPVLAIGNPFGVGQTVTGGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALVDVNGHLMGI
NTAIYSRSGGSMGIGFAIPVSTAKQVLEGIVKDGQVTRGWIGVEPQELNAELAETFNIKPAALKDGGVIIIGVLQNGPAA
QAGIQPGDVITAVNGKSVSNVSQLLTAVAALKPGTPAPLTVWRRDRQTDIAVTPGKRQRPRVQR

Sequences:

>Translated_384_residues
MKRTWLLFSQTVTVLVAAYFVVATLQPQWLGTSSIGGVSVIEAPASSVQLGPRPAGTFSSAAKIASAAVVSINTSKAAVN
NPHADDPWFKFFFGDQGRSEPQGGLGSGVIISATGYILTNNHVVEGADEIEVILNDTRKAKAQVIGTDPDTDLAILKINL
DKLPVIVLGNSDALQIGDPVLAIGNPFGVGQTVTGGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALVDVNGHLMGI
NTAIYSRSGGSMGIGFAIPVSTAKQVLEGIVKDGQVTRGWIGVEPQELNAELAETFNIKPAALKDGGVIIIGVLQNGPAA
QAGIQPGDVITAVNGKSVSNVSQLLTAVAALKPGTPAPLTVWRRDRQTDIAVTPGKRQRPRVQR
>Mature_384_residues
MKRTWLLFSQTVTVLVAAYFVVATLQPQWLGTSSIGGVSVIEAPASSVQLGPRPAGTFSSAAKIASAAVVSINTSKAAVN
NPHADDPWFKFFFGDQGRSEPQGGLGSGVIISATGYILTNNHVVEGADEIEVILNDTRKAKAQVIGTDPDTDLAILKINL
DKLPVIVLGNSDALQIGDPVLAIGNPFGVGQTVTGGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALVDVNGHLMGI
NTAIYSRSGGSMGIGFAIPVSTAKQVLEGIVKDGQVTRGWIGVEPQELNAELAETFNIKPAALKDGGVIIIGVLQNGPAA
QAGIQPGDVITAVNGKSVSNVSQLLTAVAALKPGTPAPLTVWRRDRQTDIAVTPGKRQRPRVQR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=283, Percent_Identity=36.0424028268551, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI22129776, Length=272, Percent_Identity=36.0294117647059, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=34.6456692913386, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI7019477, Length=283, Percent_Identity=36.0424028268551, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1789629, Length=311, Percent_Identity=44.6945337620579, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1786356, Length=332, Percent_Identity=44.8795180722892, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789630, Length=273, Percent_Identity=44.6886446886447, Blast_Score=204, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24646839, Length=311, Percent_Identity=33.1189710610932, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39804; Mature: 39804

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTWLLFSQTVTVLVAAYFVVATLQPQWLGTSSIGGVSVIEAPASSVQLGPRPAGTFSS
CCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCHHH
AAKIASAAVVSINTSKAAVNNPHADDPWFKFFFGDQGRSEPQGGLGSGVIISATGYILTN
HHHHHHEEEEEEECCHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEC
NHVVEGADEIEVILNDTRKAKAQVIGTDPDTDLAILKINLDKLPVIVLGNSDALQIGDPV
CEEECCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCEEECCEE
LAIGNPFGVGQTVTGGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALVDVNGHLMGI
EEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEE
NTAIYSRSGGSMGIGFAIPVSTAKQVLEGIVKDGQVTRGWIGVEPQELNAELAETFNIKP
EEEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCEEECEECCCHHHHCHHHHHHCCCCC
AALKDGGVIIIGVLQNGPAAQAGIQPGDVITAVNGKSVSNVSQLLTAVAALKPGTPAPLT
CEECCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEE
VWRRDRQTDIAVTPGKRQRPRVQR
EEECCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MKRTWLLFSQTVTVLVAAYFVVATLQPQWLGTSSIGGVSVIEAPASSVQLGPRPAGTFSS
CCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCHHH
AAKIASAAVVSINTSKAAVNNPHADDPWFKFFFGDQGRSEPQGGLGSGVIISATGYILTN
HHHHHHEEEEEEECCHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEC
NHVVEGADEIEVILNDTRKAKAQVIGTDPDTDLAILKINLDKLPVIVLGNSDALQIGDPV
CEEECCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCEEECCEE
LAIGNPFGVGQTVTGGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALVDVNGHLMGI
EEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEE
NTAIYSRSGGSMGIGFAIPVSTAKQVLEGIVKDGQVTRGWIGVEPQELNAELAETFNIKP
EEEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCEEECEECCCHHHHCHHHHHHCCCCC
AALKDGGVIIIGVLQNGPAAQAGIQPGDVITAVNGKSVSNVSQLLTAVAALKPGTPAPLT
CEECCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEE
VWRRDRQTDIAVTPGKRQRPRVQR
EEECCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]