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The map label for this gene is coxM [H]

Identifier: 91786628

GI number: 91786628

Start: 740987

End: 742153

Strand: Direct

Name: coxM [H]

Synonym: Bpro_0726

Alternate gene names: 91786628

Gene position: 740987-742153 (Clockwise)

Preceding gene: 91786627

Following gene: 91786629

Centisome position: 14.25

GC content: 65.9

Gene sequence:

>1167_bases
ATGGTTTTTGCTTATGTCCTCATTGTCATCGTCATCGGGTCGGTGCTGTTCCACTTTGTCAGTCCCTGGACGGCGACGCC
GCTGGCCTCGAACTGGCAGTCGATGGACGATACGCTGACGATCACGCTGGCAGTCACTGGCCTCTTTTTCGTCGTCATCA
ATTTTTTCGTCGCTTACACCCTGCTGCGCTATCGCCACCGCGAGGGCAGCCGCGCCGCCTATGAGCCCGAGAACCGGAAA
CTGGAGCGCTGGCTGATCGGGATCACCTCGGTAGGCATCGCATTGCTGCTGGCACCCGGGCTGCTGGTCTATGCGAAATA
CGTCAATGCGCCGGGCGATGCCATCGTGCTGGAGATACTGGGCCAGCAGTGGCAGTGGTACTACCGCTTTCCCGGCACGG
ACAGCAAGCTGGGCCTGACGGACGCGCGCTTCGTCAGCGCCGCCAACCCGTTCGGGCTGAACCCCGGCGACCCGGCCGGG
CAGGACGACTTTCTCATCGCGGGCACCGAGGTACACCTGCCACTGAACAAGCCGGTCAAGGTGCTGCTGCGCTCACACGA
TGTGCTGCACGATTTCTTCGTTCCGCCGTTCCGCGCGCGCATGAACATCGTGCCCGGCCAGGTGAGCACGTTCTGGTTCA
CCCCCACGGTGATTGGCCGTTACGAGGCGATGTGCGCCCAGCTGTGCGGCATCGGTCATCCCAATATGCGTGGCCATGTG
GTGGTGGAGGACGACGCCAAATTCCAGACCTGGTTGAAGGCGCAATCCACCTTTGCGGTGGCGCTGGCCAGCGCCAGCCG
CGCCGCGAACGCGCCACCCGCTGGTGCCGACAACCGGGTGGCCCAGGGGCAGGCGCTGGCCCAGTCCAGGGGCTGCGCCG
CCTGCCATACCGTCGACGGCAGTGCCCGTGTCGGGCCGACCTGGAAGGGACTGTACGGCGCAACGCGCCCGCTGGCGGAC
GGCTCGACGGTGCTGGCCGATGAGGGCTATTTGAGGCGCTCCATCCTCGAGCCCCAGGCCCAGGTGGTGCAGGGCTTCCC
GCCCATCATGCCGCCGGCCAGCCTGGGCGACGAGGAGATGGCCGCGTTGCTGGCCTACATCCAGTCGCTGGGCGGCGTCA
CTCCGGCTGCACCAGCTCCCGCAGCCGGGCAGAAGGCGCAGCAGTGA

Upstream 100 bases:

>100_bases
CGTGATGACCCACCTGATCTTTGGGATGACGGCCGCATTTTTGTACTGGAAGTTCAATCGGCATTGAAGAGGTGGCCGGC
GCCGAACCGAGAGGATGCGA

Downstream 100 bases:

>100_bases
ACGCCACGCCACACAACGAGGAACTCCATGGCCTACGCTGAAGATACTTCGCATCACCCGCAGAGCTTCTGGACCCGCTA
TGTCTGGAGCCAGGACCACA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Alternative cytochrome c oxidase polypeptide II; Cytochrome BB3 subunit 2; Oxidase BB(3) subunit 2 [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MVFAYVLIVIVIGSVLFHFVSPWTATPLASNWQSMDDTLTITLAVTGLFFVVINFFVAYTLLRYRHREGSRAAYEPENRK
LERWLIGITSVGIALLLAPGLLVYAKYVNAPGDAIVLEILGQQWQWYYRFPGTDSKLGLTDARFVSAANPFGLNPGDPAG
QDDFLIAGTEVHLPLNKPVKVLLRSHDVLHDFFVPPFRARMNIVPGQVSTFWFTPTVIGRYEAMCAQLCGIGHPNMRGHV
VVEDDAKFQTWLKAQSTFAVALASASRAANAPPAGADNRVAQGQALAQSRGCAACHTVDGSARVGPTWKGLYGATRPLAD
GSTVLADEGYLRRSILEPQAQVVQGFPPIMPPASLGDEEMAALLAYIQSLGGVTPAAPAPAAGQKAQQ

Sequences:

>Translated_388_residues
MVFAYVLIVIVIGSVLFHFVSPWTATPLASNWQSMDDTLTITLAVTGLFFVVINFFVAYTLLRYRHREGSRAAYEPENRK
LERWLIGITSVGIALLLAPGLLVYAKYVNAPGDAIVLEILGQQWQWYYRFPGTDSKLGLTDARFVSAANPFGLNPGDPAG
QDDFLIAGTEVHLPLNKPVKVLLRSHDVLHDFFVPPFRARMNIVPGQVSTFWFTPTVIGRYEAMCAQLCGIGHPNMRGHV
VVEDDAKFQTWLKAQSTFAVALASASRAANAPPAGADNRVAQGQALAQSRGCAACHTVDGSARVGPTWKGLYGATRPLAD
GSTVLADEGYLRRSILEPQAQVVQGFPPIMPPASLGDEEMAALLAYIQSLGGVTPAAPAPAAGQKAQQ
>Mature_388_residues
MVFAYVLIVIVIGSVLFHFVSPWTATPLASNWQSMDDTLTITLAVTGLFFVVINFFVAYTLLRYRHREGSRAAYEPENRK
LERWLIGITSVGIALLLAPGLLVYAKYVNAPGDAIVLEILGQQWQWYYRFPGTDSKLGLTDARFVSAANPFGLNPGDPAG
QDDFLIAGTEVHLPLNKPVKVLLRSHDVLHDFFVPPFRARMNIVPGQVSTFWFTPTVIGRYEAMCAQLCGIGHPNMRGHV
VVEDDAKFQTWLKAQSTFAVALASASRAANAPPAGADNRVAQGQALAQSRGCAACHTVDGSARVGPTWKGLYGATRPLAD
GSTVLADEGYLRRSILEPQAQVVQGFPPIMPPASLGDEEMAALLAYIQSLGGVTPAAPAPAAGQKAQQ

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A ce

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6226540, Length=142, Percent_Identity=27.4647887323944, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 41876; Mature: 41876

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFAYVLIVIVIGSVLFHFVSPWTATPLASNWQSMDDTLTITLAVTGLFFVVINFFVAYT
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
LLRYRHREGSRAAYEPENRKLERWLIGITSVGIALLLAPGLLVYAKYVNAPGDAIVLEIL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
GQQWQWYYRFPGTDSKLGLTDARFVSAANPFGLNPGDPAGQDDFLIAGTEVHLPLNKPVK
CCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCEEEECCCCHHH
VLLRSHDVLHDFFVPPFRARMNIVPGQVSTFWFTPTVIGRYEAMCAQLCGIGHPNMRGHV
HHHHHHHHHHHHCCCCHHHHCEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCEE
VVEDDAKFQTWLKAQSTFAVALASASRAANAPPAGADNRVAQGQALAQSRGCAACHTVDG
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCC
SARVGPTWKGLYGATRPLADGSTVLADEGYLRRSILEPQAQVVQGFPPIMPPASLGDEEM
CCCCCCCCHHHCCCCCCCCCCCEEEECCCHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHH
AALLAYIQSLGGVTPAAPAPAAGQKAQQ
HHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVFAYVLIVIVIGSVLFHFVSPWTATPLASNWQSMDDTLTITLAVTGLFFVVINFFVAYT
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
LLRYRHREGSRAAYEPENRKLERWLIGITSVGIALLLAPGLLVYAKYVNAPGDAIVLEIL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
GQQWQWYYRFPGTDSKLGLTDARFVSAANPFGLNPGDPAGQDDFLIAGTEVHLPLNKPVK
CCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCEEEECCCCHHH
VLLRSHDVLHDFFVPPFRARMNIVPGQVSTFWFTPTVIGRYEAMCAQLCGIGHPNMRGHV
HHHHHHHHHHHHCCCCHHHHCEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCEE
VVEDDAKFQTWLKAQSTFAVALASASRAANAPPAGADNRVAQGQALAQSRGCAACHTVDG
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCC
SARVGPTWKGLYGATRPLADGSTVLADEGYLRRSILEPQAQVVQGFPPIMPPASLGDEEM
CCCCCCCCHHHCCCCCCCCCCCEEEECCCHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHH
AALLAYIQSLGGVTPAAPAPAAGQKAQQ
HHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1444719; 12597275 [H]