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The map label for this gene is ywcA [H]

Identifier: 91786439

GI number: 91786439

Start: 530131

End: 531657

Strand: Reverse

Name: ywcA [H]

Synonym: Bpro_0531

Alternate gene names: 91786439

Gene position: 531657-530131 (Counterclockwise)

Preceding gene: 91786440

Following gene: 91786438

Centisome position: 10.22

GC content: 58.68

Gene sequence:

>1527_bases
ATGAAATTCATCACGCTGGGCATATTTCTGTTCATTCTGGGCATCACCCTTGCAGTGACTTACTGGGCCGCCAAACGCAC
CAAAACTACCAGCGAATTTTACGCGGCGGGGGGCAATCTGGGGGCGGTAGAAAACGGCTTTGCACTGGCCGGAGACTGGA
TGAGTGCCGCCGCTTTTCTGGGCTTTGTCGGCCTGTCCGCGTTGTTTGGCTGGGATGGCGCACTGTATGCGCTGGGTGCG
CTGGTGGCTTTCATGACCATCTTGTTGCTGGTCGCCGAGCCGCTGCGCAACACCGGCCGCTACACACTGGGCGACGTGAT
TGCCTACCGCATGCAACGCCCGCAAGCCCGGGTGGCGGCAGTGGTCGGTACCATTGTGGTTAACCTAGCGTACCTGATTC
CGCAAATGGCCGGTGGCGGTGTGTTGATCAAATTGCTGCTGGACATTCCCTACAGCGCCTCTGTGGTGTTTGTCGGCATT
GGCATGATTGTGTATGTGGCCTTTGGTGGCATGCTGGCCACCACTTGGGTGCAAATTATCAAGGCGGTGCTGCTGATTTC
TACCGCCGTCGTGCTGGTGGTGTGGATACTGGCCCTATTTGGCTTCAACCCGGTGGCGCTGTTTGACGGCATGGAGGCCA
AGTACGGCAGCAAAATATTGTCGCCAGGAAATTTCTTCAAGCACCCACTGGATGCATTCTCTCTGGGCATCAGTTTTGTG
CTGGGCACCGCCGGCCTGCCGCACATCATGACCCGCTTTTACACCGTGCCAGATGCAAAAACGGCGCGCAAATCGGTCAT
CTGGCTGATGTTTCTCGCGGGCGGATTTTTTCTTGTCACCACACTGATTGGTTTTGCCTCGGCCCTGCTGGTGGGGCAGG
ACGCCATACGCGCGGCTGACAAGGGTGGCAATCTGGCGCTCCCCCTGCTGGCGCAATACCTGGGCGGTGGGGTCGGAACT
TTGGGCGGACAGATTTTTCTGGCCTTCGTAGCAGCTGTGGCTTTTGCCACCATTTTGGCGGTGGTGGCAGGCTTGACACT
CGCCACCTCGGGAGCCATCGCTCATGACCTCTACGTCAACGTCATCAAGCAGGGCGTGCTCAGTGAAAAAGAGCAGGTCA
GGGTCGCCCGCGTCTCGGTGATCGGCATCGGCATTGTGGCTACGGTTCTGGGTTTGCTGGCGCAAGGCCAGAACGTGGCG
GTGCTGGTGATTCTGGCGATCTCGATCGCGGCGAGTGCCAATTTCCCCATCGTCGTGCTGTCGCTATTCTGGCGGCGCTT
CAACACCGGCGGTGTCATAGGCGGCGTCGGCGTGGGTTTGATATCCGCCATCGGGCTGGCACTCATTGGCCCGGCTTTCA
TGGGCAAGGAAGCGATGTTTCCCATCGTTAATCCGGCCATTGCGAGCATGCCGTTGGGCTTTTTGGGTGCCTACCTCGGG
ACCCTGCTGGGCGGCAGGAATGCCAAGCTTGAAGCCCACTTTGACCAGGTACTGTTCAAGGCCCAGACCGCCATAGCCAT
CGATTGA

Upstream 100 bases:

>100_bases
GTTGGATCATGGGTGTGATCTACGTGCGCATTGCCAACCGTGATTTCGACGTGATGGCGTCCCGGGCGGTGCATGAGCTC
GCGCACGGCAGGGGGCAAGC

Downstream 100 bases:

>100_bases
TTTTTAAAAGTTTTGGAGAACAGTATGCATGCCATCAAAGCCGTTGTTTTTGACCTGTACGGTACCTTGTACGACGTTTA
CTCTGTCCGCACCTCCTGCG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MKFITLGIFLFILGITLAVTYWAAKRTKTTSEFYAAGGNLGAVENGFALAGDWMSAAAFLGFVGLSALFGWDGALYALGA
LVAFMTILLLVAEPLRNTGRYTLGDVIAYRMQRPQARVAAVVGTIVVNLAYLIPQMAGGGVLIKLLLDIPYSASVVFVGI
GMIVYVAFGGMLATTWVQIIKAVLLISTAVVLVVWILALFGFNPVALFDGMEAKYGSKILSPGNFFKHPLDAFSLGISFV
LGTAGLPHIMTRFYTVPDAKTARKSVIWLMFLAGGFFLVTTLIGFASALLVGQDAIRAADKGGNLALPLLAQYLGGGVGT
LGGQIFLAFVAAVAFATILAVVAGLTLATSGAIAHDLYVNVIKQGVLSEKEQVRVARVSVIGIGIVATVLGLLAQGQNVA
VLVILAISIAASANFPIVVLSLFWRRFNTGGVIGGVGVGLISAIGLALIGPAFMGKEAMFPIVNPAIASMPLGFLGAYLG
TLLGGRNAKLEAHFDQVLFKAQTAIAID

Sequences:

>Translated_508_residues
MKFITLGIFLFILGITLAVTYWAAKRTKTTSEFYAAGGNLGAVENGFALAGDWMSAAAFLGFVGLSALFGWDGALYALGA
LVAFMTILLLVAEPLRNTGRYTLGDVIAYRMQRPQARVAAVVGTIVVNLAYLIPQMAGGGVLIKLLLDIPYSASVVFVGI
GMIVYVAFGGMLATTWVQIIKAVLLISTAVVLVVWILALFGFNPVALFDGMEAKYGSKILSPGNFFKHPLDAFSLGISFV
LGTAGLPHIMTRFYTVPDAKTARKSVIWLMFLAGGFFLVTTLIGFASALLVGQDAIRAADKGGNLALPLLAQYLGGGVGT
LGGQIFLAFVAAVAFATILAVVAGLTLATSGAIAHDLYVNVIKQGVLSEKEQVRVARVSVIGIGIVATVLGLLAQGQNVA
VLVILAISIAASANFPIVVLSLFWRRFNTGGVIGGVGVGLISAIGLALIGPAFMGKEAMFPIVNPAIASMPLGFLGAYLG
TLLGGRNAKLEAHFDQVLFKAQTAIAID
>Mature_508_residues
MKFITLGIFLFILGITLAVTYWAAKRTKTTSEFYAAGGNLGAVENGFALAGDWMSAAAFLGFVGLSALFGWDGALYALGA
LVAFMTILLLVAEPLRNTGRYTLGDVIAYRMQRPQARVAAVVGTIVVNLAYLIPQMAGGGVLIKLLLDIPYSASVVFVGI
GMIVYVAFGGMLATTWVQIIKAVLLISTAVVLVVWILALFGFNPVALFDGMEAKYGSKILSPGNFFKHPLDAFSLGISFV
LGTAGLPHIMTRFYTVPDAKTARKSVIWLMFLAGGFFLVTTLIGFASALLVGQDAIRAADKGGNLALPLLAQYLGGGVGT
LGGQIFLAFVAAVAFATILAVVAGLTLATSGAIAHDLYVNVIKQGVLSEKEQVRVARVSVIGIGIVATVLGLLAQGQNVA
VLVILAISIAASANFPIVVLSLFWRRFNTGGVIGGVGVGLISAIGLALIGPAFMGKEAMFPIVNPAIASMPLGFLGAYLG
TLLGGRNAKLEAHFDQVLFKAQTAIAID

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=468, Percent_Identity=25.2136752136752, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790503, Length=507, Percent_Identity=45.3648915187377, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI87082237, Length=458, Percent_Identity=23.5807860262009, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52971; Mature: 52971

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]