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The map label for this gene is dhmA [H]

Identifier: 91786430

GI number: 91786430

Start: 525589

End: 526455

Strand: Direct

Name: dhmA [H]

Synonym: Bpro_0521

Alternate gene names: 91786430

Gene position: 525589-526455 (Clockwise)

Preceding gene: 91786429

Following gene: 91786431

Centisome position: 10.11

GC content: 56.29

Gene sequence:

>867_bases
ATGCTGAACCCTGCACTCCTAAACCTCCCGTCCACTTCATACCATTTCACGGAGGTGGAAGGGCTCAACGTGTTTTATCG
AAGCGCCGGAGACCCTTGCGCGCCGACCATTGTTTTGCTGCACGGATTTCCGTCGTCATCACACATGTTCCGGGATTTGA
TTCCGCTCCTCGCCGATCGCTTTCACGTCATCGCACCCGACTACATCGGATTCGGCTATTCCGATGCGCCATCTGCGCAG
GAATTTGAATACAGTTTTCGGCATCTCACGGAAATCGTCCAGAGTCTGTTGGGGAAGTTCGGGATTGAAGCGTACTACCT
CTACATGCAGGACTACGGCGGGCCGATCGGATTACGCCTGGCCACTGCTCATCCCGAACGTGTGCTCGGCTTGGTGTTTC
AGAACGCAAACGTGTACATGGAGGGCGTGAGTCAGGCAGCCGCCGACGTATTCATGCCGCTGTGGCTGCGGGGAGACGAA
ACTGGCGCACGGCAGATGCTATTGGCACAAACAACTCGGTTCCAGTACACGCAAGGTGCCCGCAACTCAGCCTCGCTGAA
TCCAGATGCGTGGACACACGATCAAGCCCTGCTTGATCGCCCCGGCAGTGCGGACAGGCAGATGGCGCTGTTCAAGGACT
ACCAAACCAATGTAGCCCTCTACGAAGAATGGCAGGCCTATTTTCGTCAACGCCAACCCAAAAGCCTGGTGGCCTGGGGC
AAGGGGGATCCGTTTTTTGGGGTGCCCGGTGCTGAGGCATTCAAGCGTGACCTGACAAACCTCGAAGTGCACTATTTCGA
CGCAGGTCATTTTGCGCTCGAAGAGGACTGCCCGGCAATCGCAGCGCTGATCAAGCGTTATTTCTGA

Upstream 100 bases:

>100_bases
TGGAACCCAGATTGATTTTCCAGCCACTGCACCTCTGGTTGCAGCGTCCTGAGAACGATCTGCCCATTTGCCAATCGACC
CATTTTTAAGAACACAGATT

Downstream 100 bases:

>100_bases
CATTTGTACTAGCAGGAATACCAGTTATGAATAGGAAACTATCCAAGCTTGTTGTTGCGACGCTCCCGATCGCCCTTACG
GTAGTACTCGGCGCACAGGG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MLNPALLNLPSTSYHFTEVEGLNVFYRSAGDPCAPTIVLLHGFPSSSHMFRDLIPLLADRFHVIAPDYIGFGYSDAPSAQ
EFEYSFRHLTEIVQSLLGKFGIEAYYLYMQDYGGPIGLRLATAHPERVLGLVFQNANVYMEGVSQAAADVFMPLWLRGDE
TGARQMLLAQTTRFQYTQGARNSASLNPDAWTHDQALLDRPGSADRQMALFKDYQTNVALYEEWQAYFRQRQPKSLVAWG
KGDPFFGVPGAEAFKRDLTNLEVHYFDAGHFALEEDCPAIAALIKRYF

Sequences:

>Translated_288_residues
MLNPALLNLPSTSYHFTEVEGLNVFYRSAGDPCAPTIVLLHGFPSSSHMFRDLIPLLADRFHVIAPDYIGFGYSDAPSAQ
EFEYSFRHLTEIVQSLLGKFGIEAYYLYMQDYGGPIGLRLATAHPERVLGLVFQNANVYMEGVSQAAADVFMPLWLRGDE
TGARQMLLAQTTRFQYTQGARNSASLNPDAWTHDQALLDRPGSADRQMALFKDYQTNVALYEEWQAYFRQRQPKSLVAWG
KGDPFFGVPGAEAFKRDLTNLEVHYFDAGHFALEEDCPAIAALIKRYF
>Mature_288_residues
MLNPALLNLPSTSYHFTEVEGLNVFYRSAGDPCAPTIVLLHGFPSSSHMFRDLIPLLADRFHVIAPDYIGFGYSDAPSAQ
EFEYSFRHLTEIVQSLLGKFGIEAYYLYMQDYGGPIGLRLATAHPERVLGLVFQNANVYMEGVSQAAADVFMPLWLRGDE
TGARQMLLAQTTRFQYTQGARNSASLNPDAWTHDQALLDRPGSADRQMALFKDYQTNVALYEEWQAYFRQRQPKSLVAWG
KGDPFFGVPGAEAFKRDLTNLEVHYFDAGHFALEEDCPAIAALIKRYF

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=299, Percent_Identity=24.0802675585284, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562298, Length=294, Percent_Identity=20.7482993197279, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324392, Length=282, Percent_Identity=42.5531914893617, Blast_Score=222, Evalue=5e-59,
Organism=Drosophila melanogaster, GI19922580, Length=128, Percent_Identity=31.25, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 32457; Mature: 32457

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPALLNLPSTSYHFTEVEGLNVFYRSAGDPCAPTIVLLHGFPSSSHMFRDLIPLLADR
CCCCCEEECCCCCEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC
FHVIAPDYIGFGYSDAPSAQEFEYSFRHLTEIVQSLLGKFGIEAYYLYMQDYGGPIGLRL
CEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEE
ATAHPERVLGLVFQNANVYMEGVSQAAADVFMPLWLRGDETGARQMLLAQTTRFQYTQGA
ECCCHHHHHHHHEECCCCEEHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCC
RNSASLNPDAWTHDQALLDRPGSADRQMALFKDYQTNVALYEEWQAYFRQRQPKSLVAWG
CCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
KGDPFFGVPGAEAFKRDLTNLEVHYFDAGHFALEEDCPAIAALIKRYF
CCCCCCCCCCHHHHHHHHCCCEEEEEECCCEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLNPALLNLPSTSYHFTEVEGLNVFYRSAGDPCAPTIVLLHGFPSSSHMFRDLIPLLADR
CCCCCEEECCCCCEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC
FHVIAPDYIGFGYSDAPSAQEFEYSFRHLTEIVQSLLGKFGIEAYYLYMQDYGGPIGLRL
CEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEE
ATAHPERVLGLVFQNANVYMEGVSQAAADVFMPLWLRGDETGARQMLLAQTTRFQYTQGA
ECCCHHHHHHHHEECCCCEEHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCC
RNSASLNPDAWTHDQALLDRPGSADRQMALFKDYQTNVALYEEWQAYFRQRQPKSLVAWG
CCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
KGDPFFGVPGAEAFKRDLTNLEVHYFDAGHFALEEDCPAIAALIKRYF
CCCCCCCCCCHHHHHHHHCCCEEEEEECCCEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA