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The map label for this gene is glpR [H]

Identifier: 91786387

GI number: 91786387

Start: 493492

End: 494271

Strand: Reverse

Name: glpR [H]

Synonym: Bpro_0477

Alternate gene names: 91786387

Gene position: 494271-493492 (Counterclockwise)

Preceding gene: 91786417

Following gene: 91786386

Centisome position: 9.5

GC content: 63.85

Gene sequence:

>780_bases
ATGCGTACCCCCGTGAACTCCAACCCCAGGCAAATCAAGCTTCTTGACTTCGTACGCGCCCATGGCGCGGCCTCTGTTGA
GCAACTCGCCGACAAGCTGGGTGTCACCCTGCAGACCGTGCGGCGCGATGTGCAGCGCCTGGCAGATGCCGGTTTGCTGG
CACGCTTTCATGGCGGCGTGCGGGTGCCCAGCTCCACCGTCGAGAACATTGCGCACCAACAACGCAAAAGCCTCAGCGCC
GAAGGCAAGGCGCGCATTGCCCGTGCCGTGGCCCAACGCGTGCCCAACGACTGCTCGCTGATCCTCAACATCGGCACCAC
GACCGAGGCTGTTGCCAAGGCCCTGCTGCATCACAAGGGGTTGCGGGTCATCACCAACAACCTGAATGTGGCGGAGATTT
TGTGCGGCAATCCCGACTGCGAAGTCATCGTGGCCGGCGGCGTGGTGCGTGCGCGCGACCGCGGCATCGTGGGCGAGGCA
GCGGTCGATTTCATACGCCAGTTCCGGGTGGACATTGCCGTCATTGGCATCTCCGGCATCGAGCCCGATGGCTCCCTGCG
CGACTTCGACTACCGGGAGGTCAAGGTGGCCCAGGCCATCATTGCGCACGCCCGCGAGGTCTGGCTGGCCGCCGACAGCA
GCAAATTCAACCGCCCGGCCATGGTCGAGCTGGCCCAGCTGTCCCAGATAGACAGGCTGTTCACCGACAAGGCGCCACCC
GAACCTTTTCCCGCCCTGCTGGAAGAGGCCAATGTGATCTGTGAAATAGCCCACGCCTGA

Upstream 100 bases:

>100_bases
CGAATTGGCTCTATTGTTGTTCTTTTGTGATCGTTTTGTCTAATAGTTTTCCCTTAGTCTTTTCCTTTTGTTTCGATATA
GAGTGTGAAAAACTCTTGTC

Downstream 100 bases:

>100_bases
GGCAGCATCAGATCCGTCAGCCCCATCAAGCCCCTACCCCCGCCGATTGAAGCCATGACTTATTTGCTCGCCCTTGACCA
GGGCACCTCCAGCTCCCGCA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRTPVNSNPRQIKLLDFVRAHGAASVEQLADKLGVTLQTVRRDVQRLADAGLLARFHGGVRVPSSTVENIAHQQRKSLSA
EGKARIARAVAQRVPNDCSLILNIGTTTEAVAKALLHHKGLRVITNNLNVAEILCGNPDCEVIVAGGVVRARDRGIVGEA
AVDFIRQFRVDIAVIGISGIEPDGSLRDFDYREVKVAQAIIAHAREVWLAADSSKFNRPAMVELAQLSQIDRLFTDKAPP
EPFPALLEEANVICEIAHA

Sequences:

>Translated_259_residues
MRTPVNSNPRQIKLLDFVRAHGAASVEQLADKLGVTLQTVRRDVQRLADAGLLARFHGGVRVPSSTVENIAHQQRKSLSA
EGKARIARAVAQRVPNDCSLILNIGTTTEAVAKALLHHKGLRVITNNLNVAEILCGNPDCEVIVAGGVVRARDRGIVGEA
AVDFIRQFRVDIAVIGISGIEPDGSLRDFDYREVKVAQAIIAHAREVWLAADSSKFNRPAMVELAQLSQIDRLFTDKAPP
EPFPALLEEANVICEIAHA
>Mature_259_residues
MRTPVNSNPRQIKLLDFVRAHGAASVEQLADKLGVTLQTVRRDVQRLADAGLLARFHGGVRVPSSTVENIAHQQRKSLSA
EGKARIARAVAQRVPNDCSLILNIGTTTEAVAKALLHHKGLRVITNNLNVAEILCGNPDCEVIVAGGVVRARDRGIVGEA
AVDFIRQFRVDIAVIGISGIEPDGSLRDFDYREVKVAQAIIAHAREVWLAADSSKFNRPAMVELAQLSQIDRLFTDKAPP
EPFPALLEEANVICEIAHA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=46.5587044534413, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI87082344, Length=250, Percent_Identity=42, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=34.3347639484979, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=30.1310043668122, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789059, Length=244, Percent_Identity=28.6885245901639, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789519, Length=248, Percent_Identity=24.1935483870968, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787540, Length=231, Percent_Identity=29.004329004329, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790753, Length=255, Percent_Identity=27.0588235294118, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787063, Length=216, Percent_Identity=25.9259259259259, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790635, Length=239, Percent_Identity=25.9414225941423, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28107; Mature: 28107

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPVNSNPRQIKLLDFVRAHGAASVEQLADKLGVTLQTVRRDVQRLADAGLLARFHGGV
CCCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
RVPSSTVENIAHQQRKSLSAEGKARIARAVAQRVPNDCSLILNIGTTTEAVAKALLHHKG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCC
LRVITNNLNVAEILCGNPDCEVIVAGGVVRARDRGIVGEAAVDFIRQFRVDIAVIGISGI
CEEEECCCCEEEEEECCCCCCEEEECCEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCC
EPDGSLRDFDYREVKVAQAIIAHAREVWLAADSSKFNRPAMVELAQLSQIDRLFTDKAPP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
EPFPALLEEANVICEIAHA
CCHHHHHHCCHHHEEECCC
>Mature Secondary Structure
MRTPVNSNPRQIKLLDFVRAHGAASVEQLADKLGVTLQTVRRDVQRLADAGLLARFHGGV
CCCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
RVPSSTVENIAHQQRKSLSAEGKARIARAVAQRVPNDCSLILNIGTTTEAVAKALLHHKG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCC
LRVITNNLNVAEILCGNPDCEVIVAGGVVRARDRGIVGEAAVDFIRQFRVDIAVIGISGI
CEEEECCCCEEEEEECCCCCCEEEECCEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCC
EPDGSLRDFDYREVKVAQAIIAHAREVWLAADSSKFNRPAMVELAQLSQIDRLFTDKAPP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
EPFPALLEEANVICEIAHA
CCHHHHHHCCHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]