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The map label for this gene is gsiC [H]

Identifier: 91786291

GI number: 91786291

Start: 394302

End: 395255

Strand: Direct

Name: gsiC [H]

Synonym: Bpro_0381

Alternate gene names: 91786291

Gene position: 394302-395255 (Clockwise)

Preceding gene: 91786290

Following gene: 91786292

Centisome position: 7.58

GC content: 60.69

Gene sequence:

>954_bases
ATGCAGCGTTACCTGTTAAGCCGTGTTTTATATGCCTTGCCCATCATGCTCGGCGTGGCTTTTGTGTGCTTTGCGCTGGT
GCATCTGGCGCCGGGTGACCCCCTGATGTCGATCCTGCCGCCCGATGCGTCAGCCGAGCTGCAGGCGCAACTGCGCGAGC
TTTATGGCTTCAACCGTTCCCTGCCCGAACAGTTTGCGCTGTGGGTCTGGCGTGCGCTGCAAGGCGACCTGGGGGTGTCC
ATTGCCAGTAACCGCCCGGTGGCGACCGAGGTGTTGACTGCGGTCGGCAATACGCTGCGGCTCGCCGTGGTTGCCACCAC
CATCGGTTTTGTACTGGGTTGCCTGTTCGGCTTCGTGGCCGGCTACTTCCGCAATTCCTGGATAGACCGCCTGGCGTCCA
TGCTGTCGGTGATGGGCGTCAGCGTGCCGCACTACTGGCTGGGCATGGTCATGGTGATCGTGTTTTCTTCCCAGCTCGCG
TGGCTGCCCGGGACCGGTGCCGGTCCCGCAGGCTCGGGGGACTGGTCTTGGGACTGGGGGCACCTTCAGTTCCTGGTGCT
GCCCGCGCTGACGATGTCAGTCATTCCCATGGGCATCATTGCGCGCACCGTGCGTGCGCTGGTGGCCGACATCCTCGATC
AGGAGTTTATTGTCGGCCTGCGTGCCAAAGGCCTGACCCACACAGGCGTATTTTTTCACATGCTGAAGAACGCGGCGCCC
ACTGCCCTTGCCGTCATGGGGCTGCAACTGGGTTACCTCCTCGGCGGCTCGATTCTCATAGAAACCGTTTTCTCCTGGCC
GGGTACCGGCTTCTTGTTGAATTCTGCAATTTTTCAACGCGACCTACCGCTGCTGCAGGGAACCATCCTCGTCCTTGCGC
TCTTCTTTGTACTGCTCAATTTTCTGGTCGATGTATTGCAGACCCTGCTCGACCCGCGTATTGCACGCACCTGA

Upstream 100 bases:

>100_bases
AAGCTGGTTTATTGACATCGCCACCATGACGATGGACTGAAACCGGTCCCGACCCCGCCCAGCCAGTCGTCCAGCAGCTT
CCACACCCGCGAATCACCTC

Downstream 100 bases:

>100_bases
GAAGCGAAAAACACCAAGGACGAACATGGCGGCATTGACAGCTTCCTCTTCCGCTGATGCAGGCATTTCCAGTGCTTCAG
CGGCCCCGGCGATGCCGTCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQRYLLSRVLYALPIMLGVAFVCFALVHLAPGDPLMSILPPDASAELQAQLRELYGFNRSLPEQFALWVWRALQGDLGVS
IASNRPVATEVLTAVGNTLRLAVVATTIGFVLGCLFGFVAGYFRNSWIDRLASMLSVMGVSVPHYWLGMVMVIVFSSQLA
WLPGTGAGPAGSGDWSWDWGHLQFLVLPALTMSVIPMGIIARTVRALVADILDQEFIVGLRAKGLTHTGVFFHMLKNAAP
TALAVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVLLNFLVDVLQTLLDPRIART

Sequences:

>Translated_317_residues
MQRYLLSRVLYALPIMLGVAFVCFALVHLAPGDPLMSILPPDASAELQAQLRELYGFNRSLPEQFALWVWRALQGDLGVS
IASNRPVATEVLTAVGNTLRLAVVATTIGFVLGCLFGFVAGYFRNSWIDRLASMLSVMGVSVPHYWLGMVMVIVFSSQLA
WLPGTGAGPAGSGDWSWDWGHLQFLVLPALTMSVIPMGIIARTVRALVADILDQEFIVGLRAKGLTHTGVFFHMLKNAAP
TALAVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVLLNFLVDVLQTLLDPRIART
>Mature_317_residues
MQRYLLSRVLYALPIMLGVAFVCFALVHLAPGDPLMSILPPDASAELQAQLRELYGFNRSLPEQFALWVWRALQGDLGVS
IASNRPVATEVLTAVGNTLRLAVVATTIGFVLGCLFGFVAGYFRNSWIDRLASMLSVMGVSVPHYWLGMVMVIVFSSQLA
WLPGTGAGPAGSGDWSWDWGHLQFLVLPALTMSVIPMGIIARTVRALVADILDQEFIVGLRAKGLTHTGVFFHMLKNAAP
TALAVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVLLNFLVDVLQTLLDPRIART

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=315, Percent_Identity=38.4126984126984, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=34.7826086956522, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789965, Length=335, Percent_Identity=34.3283582089552, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1787761, Length=322, Percent_Identity=34.1614906832298, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787497, Length=318, Percent_Identity=29.2452830188679, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=27.8388278388278, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=23.2686980609418, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34485; Mature: 34485

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRYLLSRVLYALPIMLGVAFVCFALVHLAPGDPLMSILPPDASAELQAQLRELYGFNRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCC
LPEQFALWVWRALQGDLGVSIASNRPVATEVLTAVGNTLRLAVVATTIGFVLGCLFGFVA
CHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
GYFRNSWIDRLASMLSVMGVSVPHYWLGMVMVIVFSSQLAWLPGTGAGPAGSGDWSWDWG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
HLQFLVLPALTMSVIPMGIIARTVRALVADILDQEFIVGLRAKGLTHTGVFFHMLKNAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
TALAVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVLLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FLVDVLQTLLDPRIART
HHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MQRYLLSRVLYALPIMLGVAFVCFALVHLAPGDPLMSILPPDASAELQAQLRELYGFNRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCC
LPEQFALWVWRALQGDLGVSIASNRPVATEVLTAVGNTLRLAVVATTIGFVLGCLFGFVA
CHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
GYFRNSWIDRLASMLSVMGVSVPHYWLGMVMVIVFSSQLAWLPGTGAGPAGSGDWSWDWG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
HLQFLVLPALTMSVIPMGIIARTVRALVADILDQEFIVGLRAKGLTHTGVFFHMLKNAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
TALAVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVLLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FLVDVLQTLLDPRIART
HHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]