Click here to switch to the map view.

The map label for this gene is uvrY [H]

Identifier: 91786204

GI number: 91786204

Start: 308115

End: 308783

Strand: Reverse

Name: uvrY [H]

Synonym: Bpro_0293

Alternate gene names: 91786204

Gene position: 308783-308115 (Counterclockwise)

Preceding gene: 91786205

Following gene: 91786203

Centisome position: 5.94

GC content: 64.57

Gene sequence:

>669_bases
ATGAACACCGTGAAAATCCTGATCGGCGACGACCACCGCATCGTGCGCGAAGGCCTGAAACAGGTGCTGGCCGATGCGCC
CGAGATCGAAGTGGTGGCCGAAGCGGAAACCGGCCCGGACATCCTGCAGCGCGTCGATGCCTTGGGCGGTGACAGCGGCC
TGGATGCGGTGCTGCTCGATATTGCGCTGCCCGAGCGCGACGGCCTGGACGTGTTGCAGGCACTGAAGAAAAGCTGGCCC
CGGCTGGCGGTGCTGATGCTCAGCACCTACCCGGAAAAGCAGTACGCGGTGCGCTGCATCAAGCTGGGCGCCGCGGGTTA
CCTGAACAAAAGCGCCCATCCCGACGACATGATTGCCGCGGTGCGCAAGGTAGCCACCGGCGGCGTCTATGTGTCGGCCA
TTGCCGCCGAGGCGCTGGCCAGCGCCGTCGGCAACAGCGCCACCAAAACCGGTGGCGGTGGTGGCACCGAGTCGCTGTCG
CACCGCGAGCACCAGGTGTTCCGCCTGCTCACGGCCGGCAAGTCCGTGGGCGAAATTGGTGCACAGCTGAATCTGGCACC
CAACACCGTCAGCACTTACCGTGCGCGCATCCTTGAAAAAACCGGCACCCGCAATGACGTGGAGCTGGCTTTGTATGCCG
AGCGCCACGCCAAAACCGCCCATTTGTAG

Upstream 100 bases:

>100_bases
CGGCACGCTGGACATCTCAAGCCAGATCGGCCATGGCGCCCTGTTTAACCTCCGCATTCCGCTCTCAAATCAGTAACCTT
AACAAAGCTGCTTGCCCACC

Downstream 100 bases:

>100_bases
GGGCGGCCCTACACGGCCTCGAAGACTGCACCGCGTTTTGCGGGTGCAGCAGGCCAAACCACCCCGATGGGCCCGGCCCT
TGCATGGAGCTTGGCATCTT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNTVKILIGDDHRIVREGLKQVLADAPEIEVVAEAETGPDILQRVDALGGDSGLDAVLLDIALPERDGLDVLQALKKSWP
RLAVLMLSTYPEKQYAVRCIKLGAAGYLNKSAHPDDMIAAVRKVATGGVYVSAIAAEALASAVGNSATKTGGGGGTESLS
HREHQVFRLLTAGKSVGEIGAQLNLAPNTVSTYRARILEKTGTRNDVELALYAERHAKTAHL

Sequences:

>Translated_222_residues
MNTVKILIGDDHRIVREGLKQVLADAPEIEVVAEAETGPDILQRVDALGGDSGLDAVLLDIALPERDGLDVLQALKKSWP
RLAVLMLSTYPEKQYAVRCIKLGAAGYLNKSAHPDDMIAAVRKVATGGVYVSAIAAEALASAVGNSATKTGGGGGTESLS
HREHQVFRLLTAGKSVGEIGAQLNLAPNTVSTYRARILEKTGTRNDVELALYAERHAKTAHL
>Mature_222_residues
MNTVKILIGDDHRIVREGLKQVLADAPEIEVVAEAETGPDILQRVDALGGDSGLDAVLLDIALPERDGLDVLQALKKSWP
RLAVLMLSTYPEKQYAVRCIKLGAAGYLNKSAHPDDMIAAVRKVATGGVYVSAIAAEALASAVGNSATKTGGGGGTESLS
HREHQVFRLLTAGKSVGEIGAQLNLAPNTVSTYRARILEKTGTRNDVELALYAERHAKTAHL

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=214, Percent_Identity=34.5794392523364, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1790102, Length=210, Percent_Identity=38.5714285714286, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786747, Length=216, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788712, Length=210, Percent_Identity=28.0952380952381, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788546, Length=215, Percent_Identity=25.1162790697674, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=29.126213592233, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787473, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23513; Mature: 23513

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVKILIGDDHRIVREGLKQVLADAPEIEVVAEAETGPDILQRVDALGGDSGLDAVLLD
CCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHEEEE
IALPERDGLDVLQALKKSWPRLAVLMLSTYPEKQYAVRCIKLGAAGYLNKSAHPDDMIAA
EECCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHH
VRKVATGGVYVSAIAAEALASAVGNSATKTGGGGGTESLSHREHQVFRLLTAGKSVGEIG
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHC
AQLNLAPNTVSTYRARILEKTGTRNDVELALYAERHAKTAHL
CEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCCC
>Mature Secondary Structure
MNTVKILIGDDHRIVREGLKQVLADAPEIEVVAEAETGPDILQRVDALGGDSGLDAVLLD
CCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHEEEE
IALPERDGLDVLQALKKSWPRLAVLMLSTYPEKQYAVRCIKLGAAGYLNKSAHPDDMIAA
EECCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHH
VRKVATGGVYVSAIAAEALASAVGNSATKTGGGGGTESLSHREHQVFRLLTAGKSVGEIG
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHC
AQLNLAPNTVSTYRARILEKTGTRNDVELALYAERHAKTAHL
CEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]