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The map label for this gene is mreB [H]

Identifier: 91786133

GI number: 91786133

Start: 242403

End: 243446

Strand: Direct

Name: mreB [H]

Synonym: Bpro_0222

Alternate gene names: 91786133

Gene position: 242403-243446 (Clockwise)

Preceding gene: 91786129

Following gene: 91786134

Centisome position: 4.66

GC content: 64.75

Gene sequence:

>1044_bases
ATGTTTGAAGCATTCCGTCGGTATTTCTCGACCGACCTGGCGATTGACCTCGGTACCGCCAACACCCTGATTTTTGTACG
TGACCGCGGCATTGTGCTTGATGAGCCCTCCGTGGTGGCGATTCGCCACGAAGGCGGCCCCCAGGGCAAAAAAACCATCC
AGGCCGTCGGCCGCGAAGCCAAGGCCATGCTGGGCAAGGTGCCCGGCAACATCGAGGCCATCCGCCCGATGAAAGACGGC
GTGATTGCCGACTTCACGGTGACCGAGCAGATGCTCAAGCAGTTCATCAAGATGGTGCACCCGCGCAGCCTGCTCAAGCC
CAGCCCGCGCATCATCATCTGCGTGCCCTGCGGCTCGACCCAGGTCGAGCGCCGCGCCATCCGTGAAAGCGCCCTGGGCG
CCGGTGCCAGCGACGTCTACCTGATCGAGGAACCCATGGCCGCCGCGATTGGCGCCGGCCTGCCGGTCTCCGAGGCCAGC
GGCTCCATGGTGGTGGACATTGGCGGCGGCACCACCGAGGTCGGCGTGATCTCGCTGGGCGGCATGGTCTACAAGGGCAG
CGTGCGCGTCGGCGGCGACCGTTTCGACGAGGCCATCATCAACTACATCCGCCGCAACTACGGCATGCTGATCGGCGAGC
CAACGGCCGAGGCCATCAAGAAAAGCATAGGCTCGGCCTTTCCTGGCTCCGAAGTCAAGGAAATGGAAGTCAAGGGCCGC
AACCTGTCCGAAGGCGTGCCGCGCAGCTTCACCATTTCGAGCAACGAAATCCTTGAAGCCCTGACCGACCCGCTGAACAA
CATCGTCAGCGCCGTCAAGAATGCGCTGGAGCAGACCCCGCCCGAGCTGGGCGCCGACATCGCCGAGCGCGGCATGATGC
TGACCGGCGGTGGCGCGCTGCTGCGCGACCTGGATCGCCTGCTGGCCGAAGAAACCGGCCTGCCGGTGCTGGTGGCCGAA
GACCCGCTGACCTGCGTGGTGCGCGGTTGCGGCATTGCGCTGGAGCGCATGGATCGCCTGGGCTCCATCTTCACGTCGGA
GTAA

Upstream 100 bases:

>100_bases
AAGCTTTCGGACAGCTTTGGCCCCACTTTCTCATACTTGGTTCATCATAAAAAGCGATCGGGCAACCCAGTTTGCTCATG
CACCAACCGGATTCCTGCAT

Downstream 100 bases:

>100_bases
GGTGCTGCCGCCCGCCGTCCTTCACCAGCCCGCCTTCGCCTGCGCGCAGATCGCATGAAGCAGGGCCAGCCTGACAGCGC
ACCATGCCCTTAGGAACCCT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFEAFRRYFSTDLAIDLGTANTLIFVRDRGIVLDEPSVVAIRHEGGPQGKKTIQAVGREAKAMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHPRSLLKPSPRIIICVPCGSTQVERRAIRESALGAGASDVYLIEEPMAAAIGAGLPVSEAS
GSMVVDIGGGTTEVGVISLGGMVYKGSVRVGGDRFDEAIINYIRRNYGMLIGEPTAEAIKKSIGSAFPGSEVKEMEVKGR
NLSEGVPRSFTISSNEILEALTDPLNNIVSAVKNALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGCGIALERMDRLGSIFTSE

Sequences:

>Translated_347_residues
MFEAFRRYFSTDLAIDLGTANTLIFVRDRGIVLDEPSVVAIRHEGGPQGKKTIQAVGREAKAMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHPRSLLKPSPRIIICVPCGSTQVERRAIRESALGAGASDVYLIEEPMAAAIGAGLPVSEAS
GSMVVDIGGGTTEVGVISLGGMVYKGSVRVGGDRFDEAIINYIRRNYGMLIGEPTAEAIKKSIGSAFPGSEVKEMEVKGR
NLSEGVPRSFTISSNEILEALTDPLNNIVSAVKNALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGCGIALERMDRLGSIFTSE
>Mature_347_residues
MFEAFRRYFSTDLAIDLGTANTLIFVRDRGIVLDEPSVVAIRHEGGPQGKKTIQAVGREAKAMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHPRSLLKPSPRIIICVPCGSTQVERRAIRESALGAGASDVYLIEEPMAAAIGAGLPVSEAS
GSMVVDIGGGTTEVGVISLGGMVYKGSVRVGGDRFDEAIINYIRRNYGMLIGEPTAEAIKKSIGSAFPGSEVKEMEVKGR
NLSEGVPRSFTISSNEILEALTDPLNNIVSAVKNALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGCGIALERMDRLGSIFTSE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=349, Percent_Identity=72.4928366762178, Blast_Score=503, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6323401, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36985; Mature: 36985

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEAFRRYFSTDLAIDLGTANTLIFVRDRGIVLDEPSVVAIRHEGGPQGKKTIQAVGREA
CHHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KAMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHPRSLLKPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCH
QVERRAIRESALGAGASDVYLIEEPMAAAIGAGLPVSEASGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDRFDEAIINYIRRNYGMLIGEPTAEAIKKSIGSAFPGSEVKEMEVKGR
CEEEECCEEECCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHCCC
NLSEGVPRSFTISSNEILEALTDPLNNIVSAVKNALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGCGIALERMDRLGSIFTSE
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEAFRRYFSTDLAIDLGTANTLIFVRDRGIVLDEPSVVAIRHEGGPQGKKTIQAVGREA
CHHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KAMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHPRSLLKPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCH
QVERRAIRESALGAGASDVYLIEEPMAAAIGAGLPVSEASGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDRFDEAIINYIRRNYGMLIGEPTAEAIKKSIGSAFPGSEVKEMEVKGR
CEEEECCEEECCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHCCC
NLSEGVPRSFTISSNEILEALTDPLNNIVSAVKNALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGCGIALERMDRLGSIFTSE
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]