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The map label for this gene is rstB [H]

Identifier: 91786118

GI number: 91786118

Start: 224585

End: 225907

Strand: Reverse

Name: rstB [H]

Synonym: Bpro_0207

Alternate gene names: 91786118

Gene position: 225907-224585 (Counterclockwise)

Preceding gene: 91786119

Following gene: 91786117

Centisome position: 4.34

GC content: 66.89

Gene sequence:

>1323_bases
ATGTGGATCCGTTTTACGTCCCACCTCTACGTGCGCATCTGGCTCGCCGTGGTGGCAACCGTGGTGGTGCTCACCTTCCT
GGTGGGCGCGGCCTGGCGGCTGAGCGCCGACCCGCCGCAGCTGCCCATTCGCGAGGTGCTGGTTCACAACGCAGCGGGCG
AAGTCATCGGCACGGCGCAAACCCGGCCGGACCGCAAACTCGGCGACGACCTCGAATTTGATGTGCTCACCAAAGACGGC
CAGAGCCTGAACCTGCTGCTGCCCCGTCCCAAACGGCCGCCCGGCAACCCGCCGTGGATGCGCCCCCCTTTCGGTTTCGG
CTTTGGCTGGATGCTGGTCCTCGTAGGCCTGGCCGTGGCGCTGGGCGCCTACCCGGTGATGCGGCGCCTGACCTTGCGGC
TCGAAGCGCTGCAGCGCGGCGTGGAGCGCTGGGGCGCCGGCGACCTGTCGGCGCGCGTCAATGCCGACGGGCGTGACGAG
GTGGCTTTCCTGGCCGAACGGTTCAACCACGCGGCCGAACGCATTGAAACCCTGATGGAGTCGCACAAATCCCTGCTGGC
CAATGCCTCCCATGAGCTGCGCTCGCCATTAGCGCGCATCCGCATGGGCCTGGAATTAATGGCCCCCACGCTTGTCGCTT
CGCGTGCCTCCGGCGTTGCGCTGCCCCTTTCCTCTGAAGTTGGGGCTAATTTTCCTGGGGGCGGCCCGTCGGAAAATTCC
GGGGCGCCCAAGTACTCCCCCGCTCTTGTCGAAGAAATCTACCGCAGCATCAACGAACTCGACCAGCTGATCGACGAGAT
CCTGTTGGCCAGCCGACTCGATGCCAAGCAGGCCGATGCCGAGCCTTTTGAAACCGTGGACCTGACCGGGCTGGCCGCCG
AGGAATGCTCGCGCGTCAATGCCGAGCTGCAGGCCGAACTGGGGACCGGTCTAGGCATTGCGCCCTCCGGCCACAGCCTG
ACGGTGCAGGGCTCGCCACGGCTGCTGCGCCGGCTGATCCGCAACCTGCTGGAAAACGCCAGGCGTTACAGCAATGGCGA
CATCAGCCTGGAGCTGGCGCAAATTCGCGTTGGTATCCGGCAACTGGCCGTCGTCCGGGTTCACGATCGGGGGCCGGGCG
TGCCTGCCGGCCAGCGCGAACGCATTTTTGAGCCGTTCTACCGGCTGCCGGGTGCCAGCGAGCGCGAGGGTGGCGTCGGC
CTGGGGCTAGCGCTGGTCAAGTCCATCAGCCTGCGCCACGGCGGCAGCGTGCGCTGCGAAGCCCGTCCGGGCGGCGGCGC
GTCATTCATTGTGGAACTCCCCGCCGCAAGCCAGAGGGCATGA

Upstream 100 bases:

>100_bases
GCAGCGCGATTGAGGCCGACCCCAAAGACCCCAAGCGCATCCTCACGGTGCGCGGCGTGGGCTACGTCTTTGCCAAGCAG
CAGGATTGAAAGCGCTGTCC

Downstream 100 bases:

>100_bases
AGGTACGCCGGAAATTCTGCGTGCCCGCTCAAAAAAATCTTGCTTTCTCCTCCATTTAGGGGATGGTCATACGGAAAAGC
TTGGCCTACAGTTTCATTGT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MWIRFTSHLYVRIWLAVVATVVVLTFLVGAAWRLSADPPQLPIREVLVHNAAGEVIGTAQTRPDRKLGDDLEFDVLTKDG
QSLNLLLPRPKRPPGNPPWMRPPFGFGFGWMLVLVGLAVALGAYPVMRRLTLRLEALQRGVERWGAGDLSARVNADGRDE
VAFLAERFNHAAERIETLMESHKSLLANASHELRSPLARIRMGLELMAPTLVASRASGVALPLSSEVGANFPGGGPSENS
GAPKYSPALVEEIYRSINELDQLIDEILLASRLDAKQADAEPFETVDLTGLAAEECSRVNAELQAELGTGLGIAPSGHSL
TVQGSPRLLRRLIRNLLENARRYSNGDISLELAQIRVGIRQLAVVRVHDRGPGVPAGQRERIFEPFYRLPGASEREGGVG
LGLALVKSISLRHGGSVRCEARPGGGASFIVELPAASQRA

Sequences:

>Translated_440_residues
MWIRFTSHLYVRIWLAVVATVVVLTFLVGAAWRLSADPPQLPIREVLVHNAAGEVIGTAQTRPDRKLGDDLEFDVLTKDG
QSLNLLLPRPKRPPGNPPWMRPPFGFGFGWMLVLVGLAVALGAYPVMRRLTLRLEALQRGVERWGAGDLSARVNADGRDE
VAFLAERFNHAAERIETLMESHKSLLANASHELRSPLARIRMGLELMAPTLVASRASGVALPLSSEVGANFPGGGPSENS
GAPKYSPALVEEIYRSINELDQLIDEILLASRLDAKQADAEPFETVDLTGLAAEECSRVNAELQAELGTGLGIAPSGHSL
TVQGSPRLLRRLIRNLLENARRYSNGDISLELAQIRVGIRQLAVVRVHDRGPGVPAGQRERIFEPFYRLPGASEREGGVG
LGLALVKSISLRHGGSVRCEARPGGGASFIVELPAASQRA
>Mature_440_residues
MWIRFTSHLYVRIWLAVVATVVVLTFLVGAAWRLSADPPQLPIREVLVHNAAGEVIGTAQTRPDRKLGDDLEFDVLTKDG
QSLNLLLPRPKRPPGNPPWMRPPFGFGFGWMLVLVGLAVALGAYPVMRRLTLRLEALQRGVERWGAGDLSARVNADGRDE
VAFLAERFNHAAERIETLMESHKSLLANASHELRSPLARIRMGLELMAPTLVASRASGVALPLSSEVGANFPGGGPSENS
GAPKYSPALVEEIYRSINELDQLIDEILLASRLDAKQADAEPFETVDLTGLAAEECSRVNAELQAELGTGLGIAPSGHSL
TVQGSPRLLRRLIRNLLENARRYSNGDISLELAQIRVGIRQLAVVRVHDRGPGVPAGQRERIFEPFYRLPGASEREGGVG
LGLALVKSISLRHGGSVRCEARPGGGASFIVELPAASQRA

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=335, Percent_Identity=29.8507462686567, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790346, Length=269, Percent_Identity=32.7137546468402, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788393, Length=303, Percent_Identity=30.6930693069307, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789808, Length=341, Percent_Identity=28.4457478005865, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790551, Length=306, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786783, Length=331, Percent_Identity=26.5861027190332, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693157, Length=288, Percent_Identity=26.0416666666667, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=342, Percent_Identity=27.1929824561404, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789149, Length=345, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=288, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=272, Percent_Identity=30.5147058823529, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=25.6809338521401, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47646; Mature: 47646

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIRFTSHLYVRIWLAVVATVVVLTFLVGAAWRLSADPPQLPIREVLVHNAAGEVIGTAQ
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHCCCCEEECCC
TRPDRKLGDDLEFDVLTKDGQSLNLLLPRPKRPPGNPPWMRPPFGFGFGWMLVLVGLAVA
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGAYPVMRRLTLRLEALQRGVERWGAGDLSARVNADGRDEVAFLAERFNHAAERIETLME
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SHKSLLANASHELRSPLARIRMGLELMAPTLVASRASGVALPLSSEVGANFPGGGPSENS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCCCCCCCCCC
GAPKYSPALVEEIYRSINELDQLIDEILLASRLDAKQADAEPFETVDLTGLAAEECSRVN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEECCCCCCHHHHHHCC
AELQAELGTGLGIAPSGHSLTVQGSPRLLRRLIRNLLENARRYSNGDISLELAQIRVGIR
HHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
QLAVVRVHDRGPGVPAGQRERIFEPFYRLPGASEREGGVGLGLALVKSISLRHGGSVRCE
HEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
ARPGGGASFIVELPAASQRA
CCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MWIRFTSHLYVRIWLAVVATVVVLTFLVGAAWRLSADPPQLPIREVLVHNAAGEVIGTAQ
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHCCCCEEECCC
TRPDRKLGDDLEFDVLTKDGQSLNLLLPRPKRPPGNPPWMRPPFGFGFGWMLVLVGLAVA
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGAYPVMRRLTLRLEALQRGVERWGAGDLSARVNADGRDEVAFLAERFNHAAERIETLME
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SHKSLLANASHELRSPLARIRMGLELMAPTLVASRASGVALPLSSEVGANFPGGGPSENS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCCCCCCCCCC
GAPKYSPALVEEIYRSINELDQLIDEILLASRLDAKQADAEPFETVDLTGLAAEECSRVN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEECCCCCCHHHHHHCC
AELQAELGTGLGIAPSGHSLTVQGSPRLLRRLIRNLLENARRYSNGDISLELAQIRVGIR
HHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
QLAVVRVHDRGPGVPAGQRERIFEPFYRLPGASEREGGVGLGLALVKSISLRHGGSVRCE
HEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
ARPGGGASFIVELPAASQRA
CCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]