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The map label for this gene is btuE [C]

Identifier: 91786101

GI number: 91786101

Start: 208345

End: 208830

Strand: Reverse

Name: btuE [C]

Synonym: Bpro_0190

Alternate gene names: 91786101

Gene position: 208830-208345 (Counterclockwise)

Preceding gene: 91786102

Following gene: 91786100

Centisome position: 4.02

GC content: 61.52

Gene sequence:

>486_bases
ATGAACACCGTTTACGCTTTTGAAGCCCGCCAGATCAATGGCCAGAACATCCCGCTTTCCGAATTCAGCGGCAAGGTGAT
GCTGATCGTGAACACCGCCAGCCAGTGCGGCTTCACGCCGCAGTTTGGCGGGCTGGAAGAACTGCACAAAACCTATGCCG
GCAAGGGGCTGGCGGTGCTGGGCTTTCCGTGCAACCAGTTTGGTTCGCAGGACCCGGGCAGCGATGGCGAAATCGCCGAG
TTCTGCCAGGTCAACTACGGGGTCAGTTTTCCCATGATGTCCAAGATCGACGTCAACGGCCCCGCCGCGCACCCGCTGTA
CAAGTGGCTGACCGCCGAGGCGCCGGGGCTGCTGGGCAGCAAGTCCATCAAATGGAACTTCACCAAGTTCCTGGTCGGCA
AGAACGGCCAGGTGATCAAGCGCTATGCACCGACCGACAAGCCCGCCGAGCTGGCCCGGGACATTGAGGCAGCGCTGGCC
GCCTGA

Upstream 100 bases:

>100_bases
CCTGATTGTGCTGGCCGCCCTGCTGGCCGCGCTGGCGCCGCCACCGCAAACTGGCGCAAAATGACTATGAGCCAAGCCGG
CTCCGGCAAGGAGCAATCCC

Downstream 100 bases:

>100_bases
TGGATTTTTCACAGCCGGTTCGACAGGAGAGTCAAGCCATGAGTACGGAGGCCACGCACCTTGAGGGCGGTTGCACCTGT
CGCTTTGTGCGCTACCGCAT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MNTVYAFEARQINGQNIPLSEFSGKVMLIVNTASQCGFTPQFGGLEELHKTYAGKGLAVLGFPCNQFGSQDPGSDGEIAE
FCQVNYGVSFPMMSKIDVNGPAAHPLYKWLTAEAPGLLGSKSIKWNFTKFLVGKNGQVIKRYAPTDKPAELARDIEAALA
A

Sequences:

>Translated_161_residues
MNTVYAFEARQINGQNIPLSEFSGKVMLIVNTASQCGFTPQFGGLEELHKTYAGKGLAVLGFPCNQFGSQDPGSDGEIAE
FCQVNYGVSFPMMSKIDVNGPAAHPLYKWLTAEAPGLLGSKSIKWNFTKFLVGKNGQVIKRYAPTDKPAELARDIEAALA
A
>Mature_161_residues
MNTVYAFEARQINGQNIPLSEFSGKVMLIVNTASQCGFTPQFGGLEELHKTYAGKGLAVLGFPCNQFGSQDPGSDGEIAE
FCQVNYGVSFPMMSKIDVNGPAAHPLYKWLTAEAPGLLGSKSIKWNFTKFLVGKNGQVIKRYAPTDKPAELARDIEAALA
A

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=157, Percent_Identity=47.1337579617834, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI90903240, Length=157, Percent_Identity=47.1337579617834, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI192455698, Length=161, Percent_Identity=39.7515527950311, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI15618997, Length=154, Percent_Identity=43.5064935064935, Blast_Score=125, Evalue=1e-29,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=47.7272727272727, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=33.879781420765, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=35.8381502890173, Blast_Score=97, Evalue=6e-21,
Organism=Homo sapiens, GI4557629, Length=177, Percent_Identity=34.4632768361582, Blast_Score=96, Evalue=9e-21,
Organism=Homo sapiens, GI33186887, Length=173, Percent_Identity=33.5260115606936, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI32967607, Length=183, Percent_Identity=29.5081967213115, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1788003, Length=180, Percent_Identity=42.2222222222222, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17535473, Length=162, Percent_Identity=47.5308641975309, Blast_Score=156, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=45, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=41.25, Blast_Score=135, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=37.6543209876543, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=31.7073170731707, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=29.8780487804878, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=37.8947368421053, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=53.1645569620253, Blast_Score=193, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=53.4591194968553, Blast_Score=187, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=45.9119496855346, Blast_Score=154, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=47.5, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=47.5, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=47.5, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=42.7672955974843, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17364; Mature: 17364

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVYAFEARQINGQNIPLSEFSGKVMLIVNTASQCGFTPQFGGLEELHKTYAGKGLAVL
CCCEEEEEEEECCCCCCCHHHCCCEEEEEEECHHHCCCCCCCCCHHHHHHHHCCCCEEEE
GFPCNQFGSQDPGSDGEIAEFCQVNYGVSFPMMSKIDVNGPAAHPLYKWLTAEAPGLLGS
ECCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCC
KSIKWNFTKFLVGKNGQVIKRYAPTDKPAELARDIEAALAA
CCEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTVYAFEARQINGQNIPLSEFSGKVMLIVNTASQCGFTPQFGGLEELHKTYAGKGLAVL
CCCEEEEEEEECCCCCCCHHHCCCEEEEEEECHHHCCCCCCCCCHHHHHHHHCCCCEEEE
GFPCNQFGSQDPGSDGEIAEFCQVNYGVSFPMMSKIDVNGPAAHPLYKWLTAEAPGLLGS
ECCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCC
KSIKWNFTKFLVGKNGQVIKRYAPTDKPAELARDIEAALAA
CCEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]