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The map label for this gene is fabG [H]

Identifier: 91786013

GI number: 91786013

Start: 104975

End: 105679

Strand: Reverse

Name: fabG [H]

Synonym: Bpro_0101

Alternate gene names: 91786013

Gene position: 105679-104975 (Counterclockwise)

Preceding gene: 91786014

Following gene: 91786010

Centisome position: 2.03

GC content: 63.4

Gene sequence:

>705_bases
ATGAAAATCGAGAATTCTGTTGTCCTCGTCACCGGTGCCAATCGCGGCATCGGCCAGGCGTTCTCTCGCGAGTTGCTCGC
CCGCGGTGCCCGCAAGGTCTACGCTGGCGCGCGCGATCCTGCGACCGTCACCCAATCCGGTGTTCAGGCCCTGCGACTCG
ACGTCACCAAGCCGGCAGACGTGGCCGCCGCCGCAGCGCTGGCGTCGGATGTCACGCTGATCATCAACAACGCCGGCATT
GCCCAGCCTGGAGGCTTTCTCGCAGCGGACAGCGAAGACGTCGCACGGCGCATCTTCGAGACCAACTTTTTCGCCATGTT
GCGCATGAGCAAGGCCTTTGCGCCCATTCTCAAGGCCAACGGCGGTGGCGCGTTGCTCAATGTGTTGTCGGTCGCTTCAT
GGGTGAACGGCGGCGAGCTGGCCGCCTATTCGGCCAGCAAGTCCGCAGCTTGGTCTCTCACCAATGCCCTGCGCAACGAA
CTGGCGACGCAGAAGACGCAGGTGCTGGCACTGCACATGGCCTACGTCGATACCGATCTCACGCACGGGTTCGATGTCCC
GAAGTCCAGCCCTGAGGAGATCGTCAAGCGCGCGCTCGACGGACTCGAATCGGGCCTTGATGAAGTGCTGGCCGATGAGC
TCACCCTGCAAGTCAAGCGCGGGATGACGGTGGCCAGGCCCAGCTACCTACCGCAGGCCTCCTGA

Upstream 100 bases:

>100_bases
AGGTCGTCGTCAAGATCAAGTGAGTTTGTTCATGTCAGTGTTGCTGGAAAACCTGAAAGCCGGCCGCTGAATCTGTTTGT
CCCCCACTTTGGAGATTCCT

Downstream 100 bases:

>100_bases
GGCCTGAATTCGATCGTCAGCCCCGCCCTCTGCCAACGACAAAGTCTCGAACGACCTGCATTCACTCAAGGGGCATCATG
CTTTTCGCCCCTCTCGTCGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKIENSVVLVTGANRGIGQAFSRELLARGARKVYAGARDPATVTQSGVQALRLDVTKPADVAAAAALASDVTLIINNAGI
AQPGGFLAADSEDVARRIFETNFFAMLRMSKAFAPILKANGGGALLNVLSVASWVNGGELAAYSASKSAAWSLTNALRNE
LATQKTQVLALHMAYVDTDLTHGFDVPKSSPEEIVKRALDGLESGLDEVLADELTLQVKRGMTVARPSYLPQAS

Sequences:

>Translated_234_residues
MKIENSVVLVTGANRGIGQAFSRELLARGARKVYAGARDPATVTQSGVQALRLDVTKPADVAAAAALASDVTLIINNAGI
AQPGGFLAADSEDVARRIFETNFFAMLRMSKAFAPILKANGGGALLNVLSVASWVNGGELAAYSASKSAAWSLTNALRNE
LATQKTQVLALHMAYVDTDLTHGFDVPKSSPEEIVKRALDGLESGLDEVLADELTLQVKRGMTVARPSYLPQAS
>Mature_234_residues
MKIENSVVLVTGANRGIGQAFSRELLARGARKVYAGARDPATVTQSGVQALRLDVTKPADVAAAAALASDVTLIINNAGI
AQPGGFLAADSEDVARRIFETNFFAMLRMSKAFAPILKANGGGALLNVLSVASWVNGGELAAYSASKSAAWSLTNALRNE
LATQKTQVLALHMAYVDTDLTHGFDVPKSSPEEIVKRALDGLESGLDEVLADELTLQVKRGMTVARPSYLPQAS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI142976729, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082160, Length=213, Percent_Identity=28.169014084507, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789208, Length=211, Percent_Identity=29.3838862559242, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=221, Percent_Identity=29.4117647058824, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=34.4444444444444, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=210, Percent_Identity=30.4761904761905, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=27.5, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24597; Mature: 24597

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIENSVVLVTGANRGIGQAFSRELLARGARKVYAGARDPATVTQSGVQALRLDVTKPAD
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCHH
VAAAAALASDVTLIINNAGIAQPGGFLAADSEDVARRIFETNFFAMLRMSKAFAPILKAN
HHHHHHHHCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GGGALLNVLSVASWVNGGELAAYSASKSAAWSLTNALRNELATQKTQVLALHMAYVDTDL
CCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
THGFDVPKSSPEEIVKRALDGLESGLDEVLADELTLQVKRGMTVARPSYLPQAS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
>Mature Secondary Structure
MKIENSVVLVTGANRGIGQAFSRELLARGARKVYAGARDPATVTQSGVQALRLDVTKPAD
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCHH
VAAAAALASDVTLIINNAGIAQPGGFLAADSEDVARRIFETNFFAMLRMSKAFAPILKAN
HHHHHHHHCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GGGALLNVLSVASWVNGGELAAYSASKSAAWSLTNALRNELATQKTQVLALHMAYVDTDL
CCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
THGFDVPKSSPEEIVKRALDGLESGLDEVLADELTLQVKRGMTVARPSYLPQAS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]