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The map label for this gene is leuE [H]

Identifier: 91785988

GI number: 91785988

Start: 78774

End: 79400

Strand: Direct

Name: leuE [H]

Synonym: Bpro_0075

Alternate gene names: 91785988

Gene position: 78774-79400 (Clockwise)

Preceding gene: 91785987

Following gene: 91785989

Centisome position: 1.51

GC content: 60.45

Gene sequence:

>627_bases
ATGCTGGGCTCATTCGTCGGTGTTGCCGATTACGGCGCTTTTGTTGTCGCGATCATTGTGTTTCTGTTGATTCCCGGGCC
CGGCAACCTGGCGCTGATCACCTCGACCGGCAAGGGCGGAATTCCGGGTGGACTGGGAGCCACCTTGGGCGTGATTGCCG
GCGACCAGGTCTTGCTCTGGGCGGCCGTGGCTGGGGTGGCCGCCGTGATGGCTGCCTACCCGACGGCTTTTCATGCCGTG
CAGTGGATGGGTGCCATTTACCTGACCTGGCTGGGCATCAAGATGCTGATCGCCAAGCCCGGCGATGCACCCCTCCTGCA
AATCAAGCCGCGTCATTATTTCCGCCAGGCCGTGCTGATCACCTTGCTCAACCCCAAGGCGATCGTTTTCTACATGGCCT
TCTTCCCGCTGTTTGTCGATCCGGCACAGCACCAGGGCCTGAAGACTTTTGGCGTGATGGCGGCGACGATTGCCGTCCTG
ACCTTCCTGTATGGCCTGACCTCGGTCATGCTGACCTATCACCTCGCGGAACGCATTCGCGCCAACCCGCAGATCTCTGC
CGTCCTGAACAAGCTGGCAGGCGTTTTCCTGATCGGCTTTGGCCTGAAGCTGGCGGTTTCCAAATGA

Upstream 100 bases:

>100_bases
CTTCGCCGTGTCGTTGTGCGCGGCACGAAAGACAGGTTCATTCGCGTTGGCGTCGTGACCCCTGTCGTAAACTCAAGCCC
TCTACTTCCGGAGAAATTCC

Downstream 100 bases:

>100_bases
ACAATAAAAATCCCACGAACGACAAAATGCAATTTTTCGACGGGCCGCCCCTAGAAAAATTAGCCCCCTCGGGGGGCAGC
GCCTTACACGCAGTGAAAAG

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MLGSFVGVADYGAFVVAIIVFLLIPGPGNLALITSTGKGGIPGGLGATLGVIAGDQVLLWAAVAGVAAVMAAYPTAFHAV
QWMGAIYLTWLGIKMLIAKPGDAPLLQIKPRHYFRQAVLITLLNPKAIVFYMAFFPLFVDPAQHQGLKTFGVMAATIAVL
TFLYGLTSVMLTYHLAERIRANPQISAVLNKLAGVFLIGFGLKLAVSK

Sequences:

>Translated_208_residues
MLGSFVGVADYGAFVVAIIVFLLIPGPGNLALITSTGKGGIPGGLGATLGVIAGDQVLLWAAVAGVAAVMAAYPTAFHAV
QWMGAIYLTWLGIKMLIAKPGDAPLLQIKPRHYFRQAVLITLLNPKAIVFYMAFFPLFVDPAQHQGLKTFGVMAATIAVL
TFLYGLTSVMLTYHLAERIRANPQISAVLNKLAGVFLIGFGLKLAVSK
>Mature_208_residues
MLGSFVGVADYGAFVVAIIVFLLIPGPGNLALITSTGKGGIPGGLGATLGVIAGDQVLLWAAVAGVAAVMAAYPTAFHAV
QWMGAIYLTWLGIKMLIAKPGDAPLLQIKPRHYFRQAVLITLLNPKAIVFYMAFFPLFVDPAQHQGLKTFGVMAATIAVL
TFLYGLTSVMLTYHLAERIRANPQISAVLNKLAGVFLIGFGLKLAVSK

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=204, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI48994979, Length=200, Percent_Identity=30.5, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21956; Mature: 21956

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSFVGVADYGAFVVAIIVFLLIPGPGNLALITSTGKGGIPGGLGATLGVIAGDQVLLW
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHH
AAVAGVAAVMAAYPTAFHAVQWMGAIYLTWLGIKMLIAKPGDAPLLQIKPRHYFRQAVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECHHHHHHHHHHH
TLLNPKAIVFYMAFFPLFVDPAQHQGLKTFGVMAATIAVLTFLYGLTSVMLTYHLAERIR
HHCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANPQISAVLNKLAGVFLIGFGLKLAVSK
CCCHHHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MLGSFVGVADYGAFVVAIIVFLLIPGPGNLALITSTGKGGIPGGLGATLGVIAGDQVLLW
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHH
AAVAGVAAVMAAYPTAFHAVQWMGAIYLTWLGIKMLIAKPGDAPLLQIKPRHYFRQAVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECHHHHHHHHHHH
TLLNPKAIVFYMAFFPLFVDPAQHQGLKTFGVMAATIAVLTFLYGLTSVMLTYHLAERIR
HHCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANPQISAVLNKLAGVFLIGFGLKLAVSK
CCCHHHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]