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The map label for this gene is minD [H]

Identifier: 91785932

GI number: 91785932

Start: 18736

End: 19554

Strand: Reverse

Name: minD [H]

Synonym: Bpro_0019

Alternate gene names: 91785932

Gene position: 19554-18736 (Counterclockwise)

Preceding gene: 91785933

Following gene: 91785931

Centisome position: 0.38

GC content: 63.13

Gene sequence:

>819_bases
ATGGCAAAAATCATTGTGGTCACCTCCGGCAAGGGCGGCGTGGGCAAAACCACCACCAGCGCCAGCTTTGCAACCGCCCT
GGCCCTGCGCGGCCACAAAACCGCGGTGATCGACTTCGACGTCGGCCTGCGCAACCTGGACCTCATCATGGGCTGCGAGC
GTCGCGTGGTGTACGACCTCATCAACGTCATCCACGGCGAAGCCACGCTCAACCAGGCGCTCATCAAGGACAAGCAGTGC
CACAACCTCTACGTGCTGGCCGCCTCGCAGACCCGCGACAAGGACGCGCTGACCAAGGACGGCGTGGAGAAAGTCCTGAA
GGACCTGGCCACGATGGACTTTGAATACATCGTCTGCGACTCGCCCGCCGGCATTGAAACCGGCGCGCTGCTGGCCATGC
ACTTTGCCGACGAGGCGCTGGTCGTGACCAACCCCGAGGTGTCCTCGGTGCGCGACTCCGACCGCATCCTGGGCATGCTC
TCGAGCAAGACCAAGCGCGCGATTGACGGCGGCGACCCGATCAAGGAGCACCTGCTCATCACCCGCTACAACCCCAGCCG
CGTCGACCAGGGGCAAATGCTGTCGCTCGAAGACATCAAGGACATCCTGCGCATCAAGCTGATCGGCGTGATTCCCGAGT
CCGAGTCGGTGCTGCAGGCCTCCAACCAGGGGGTGCCGGCGGTACACATTCACGGCAGCGATGTGTCGGAAGCCTACAAG
GACGTGGTCGACCGCTTCCTCGGCGACAAGGACAAGCCGCTGCGCTTCATCGACGCGCAAAAGCCCGGCCTGCTGAAACG
CTGGTTTGGAGGAAAGTGA

Upstream 100 bases:

>100_bases
CCGGGGCGGAGGGCGAGGGCGACAAGCTGGTCATGACCGTCATGGGCGCCTGAATAACACGCACGACCCCTCTCTACCGT
TTTCAAAAGGACATTTACGA

Downstream 100 bases:

>100_bases
CACGATGGCTTCATTCCTGTCCTTCCTGCTCGGCGAAAAGAAACAAACCGCCAGCGTCGCCAAGGAGCGGCTGCAGATCA
TCCTGGCGCACGAGCGCACC

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MAKIIVVTSGKGGVGKTTTSASFATALALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIHGEATLNQALIKDKQC
HNLYVLAASQTRDKDALTKDGVEKVLKDLATMDFEYIVCDSPAGIETGALLAMHFADEALVVTNPEVSSVRDSDRILGML
SSKTKRAIDGGDPIKEHLLITRYNPSRVDQGQMLSLEDIKDILRIKLIGVIPESESVLQASNQGVPAVHIHGSDVSEAYK
DVVDRFLGDKDKPLRFIDAQKPGLLKRWFGGK

Sequences:

>Translated_272_residues
MAKIIVVTSGKGGVGKTTTSASFATALALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIHGEATLNQALIKDKQC
HNLYVLAASQTRDKDALTKDGVEKVLKDLATMDFEYIVCDSPAGIETGALLAMHFADEALVVTNPEVSSVRDSDRILGML
SSKTKRAIDGGDPIKEHLLITRYNPSRVDQGQMLSLEDIKDILRIKLIGVIPESESVLQASNQGVPAVHIHGSDVSEAYK
DVVDRFLGDKDKPLRFIDAQKPGLLKRWFGGK
>Mature_271_residues
AKIIVVTSGKGGVGKTTTSASFATALALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIHGEATLNQALIKDKQCH
NLYVLAASQTRDKDALTKDGVEKVLKDLATMDFEYIVCDSPAGIETGALLAMHFADEALVVTNPEVSSVRDSDRILGMLS
SKTKRAIDGGDPIKEHLLITRYNPSRVDQGQMLSLEDIKDILRIKLIGVIPESESVLQASNQGVPAVHIHGSDVSEAYKD
VVDRFLGDKDKPLRFIDAQKPGLLKRWFGGK

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=271, Percent_Identity=70.8487084870849, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29652; Mature: 29520

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIVVTSGKGGVGKTTTSASFATALALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDL
CEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHH
INVIHGEATLNQALIKDKQCHNLYVLAASQTRDKDALTKDGVEKVLKDLATMDFEYIVCD
HHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
SPAGIETGALLAMHFADEALVVTNPEVSSVRDSDRILGMLSSKTKRAIDGGDPIKEHLLI
CCCCCCCCCEEEEEECCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHCEEE
TRYNPSRVDQGQMLSLEDIKDILRIKLIGVIPESESVLQASNQGVPAVHIHGSDVSEAYK
EECCCCCCCCCCEECHHHHHHHHHEEEEEECCCCHHHHHHCCCCCCEEEEECCCHHHHHH
DVVDRFLGDKDKPLRFIDAQKPGLLKRWFGGK
HHHHHHHCCCCCCEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
AKIIVVTSGKGGVGKTTTSASFATALALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDL
EEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHH
INVIHGEATLNQALIKDKQCHNLYVLAASQTRDKDALTKDGVEKVLKDLATMDFEYIVCD
HHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
SPAGIETGALLAMHFADEALVVTNPEVSSVRDSDRILGMLSSKTKRAIDGGDPIKEHLLI
CCCCCCCCCEEEEEECCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHCEEE
TRYNPSRVDQGQMLSLEDIKDILRIKLIGVIPESESVLQASNQGVPAVHIHGSDVSEAYK
EECCCCCCCCCCEECHHHHHHHHHEEEEEECCCCHHHHHHCCCCCCEEEEECCCHHHHHH
DVVDRFLGDKDKPLRFIDAQKPGLLKRWFGGK
HHHHHHHCCCCCCEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]