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The map label for this gene is livH [H]

Identifier: 91785753

GI number: 91785753

Start: 4826018

End: 4826902

Strand: Reverse

Name: livH [H]

Synonym: Bxe_A0020

Alternate gene names: 91785753

Gene position: 4826902-4826018 (Counterclockwise)

Preceding gene: 91785754

Following gene: 91785752

Centisome position: 98.59

GC content: 62.15

Gene sequence:

>885_bases
ATGGAAATCTTTGGCGTTCCGCTACCGGCGATGCTCAGCCAGCTGTTGCTGGGGCTCGTGAACGGCTCGTTCTACGCAAT
TCTGAGTCTCGGGCTGGCGGTGATCTTCGGCTTGCTCAATGTGATCAACTTTGCGCACGGTGCGTTGTTCATGCTCGGCG
CGATGCTCGCGTGGATGGGGCTGTCGTATTTCGGCTTGCCGTACTGGGTGATGCTCGTGCTGGCGCCGTTGATCGTGGGG
CTGTTCGGCATGGCGATCGAACGCTCGATGCTGCGCTGGCTCTACAAGCTCGACCATCTGTATGGCCTGTTGCTGACCTT
CGGACTCACGCTGGTGGTGGAGGGCGTGTTCCGTTCCATCTACGGTTCCTCTGGCCAGCCGTACGACGTGCCGTCGGCGC
TTTCGGGCGCGACCAATCTCGGCTTCATGTTCCTGCCGAACTATCGCGCGTGGGTCGTGGTGGCCTCGCTGGTGGTGTGC
TTCGCGACGTGGTTCGTGATCGAGAAGACGCGTCTTGGCGCATATCTGCGCGCCGGCACGGAAAACCCGAAGCTGGTCGA
AGCGTTCGGCATCAACGTGCCGCTGATGATCACGCTCACATACGGCTTCGGCGTCGCGCTGGCGGCATTTGCCGGTGTGC
TCGCCGCTCCGGTGATCCAGGTCTCGCCGCTGATGGGGCAGCCGATGATCATCACCGTGTTCGCGGTGGTCGTGATCGGC
GGCATGGGGTCGATCATGGGCTCGATTCTCACCGGCTTGATGCTCGGCGTGATCGAGGGGCTGACGCGCGTGTTTTACCC
GGAAGCGTCGGCGACCGTCGTCTTCGTGATCATGGCGCTCGTGTTGCTGGTGCGCCCGGCGGGTCTCTTCGGCAAGGAAA
AATGA

Upstream 100 bases:

>100_bases
CCGGTTCACATGCCGCGCGCGATTGGCGTCGCTGCCGCTGATCGCGCGCCGGCCGGATCGTGCGTGACCGATCTCACCTT
GGCGATGGGTTAAGGCTTCA

Downstream 100 bases:

>100_bases
TGCAGAGAAAAGTGCTCTACGGTCTGCTGCTGATCGTGCTTCTCGCGGTGCCCGTGCTCGGCATCTATCCGCTCTTCGTG
ATGAAGGTGATGTGCTTCGC

Product: branched chain amino acid ABC transporter inner membrane protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEIFGVPLPAMLSQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAMLAWMGLSYFGLPYWVMLVLAPLIVG
LFGMAIERSMLRWLYKLDHLYGLLLTFGLTLVVEGVFRSIYGSSGQPYDVPSALSGATNLGFMFLPNYRAWVVVASLVVC
FATWFVIEKTRLGAYLRAGTENPKLVEAFGINVPLMITLTYGFGVALAAFAGVLAAPVIQVSPLMGQPMIITVFAVVVIG
GMGSIMGSILTGLMLGVIEGLTRVFYPEASATVVFVIMALVLLVRPAGLFGKEK

Sequences:

>Translated_294_residues
MEIFGVPLPAMLSQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAMLAWMGLSYFGLPYWVMLVLAPLIVG
LFGMAIERSMLRWLYKLDHLYGLLLTFGLTLVVEGVFRSIYGSSGQPYDVPSALSGATNLGFMFLPNYRAWVVVASLVVC
FATWFVIEKTRLGAYLRAGTENPKLVEAFGINVPLMITLTYGFGVALAAFAGVLAAPVIQVSPLMGQPMIITVFAVVVIG
GMGSIMGSILTGLMLGVIEGLTRVFYPEASATVVFVIMALVLLVRPAGLFGKEK
>Mature_294_residues
MEIFGVPLPAMLSQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAMLAWMGLSYFGLPYWVMLVLAPLIVG
LFGMAIERSMLRWLYKLDHLYGLLLTFGLTLVVEGVFRSIYGSSGQPYDVPSALSGATNLGFMFLPNYRAWVVVASLVVC
FATWFVIEKTRLGAYLRAGTENPKLVEAFGINVPLMITLTYGFGVALAAFAGVLAAPVIQVSPLMGQPMIITVFAVVVIG
GMGSIMGSILTGLMLGVIEGLTRVFYPEASATVVFVIMALVLLVRPAGLFGKEK

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=307, Percent_Identity=28.6644951140065, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 31520; Mature: 31520

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFGVPLPAMLSQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAMLAWMG
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYFGLPYWVMLVLAPLIVGLFGMAIERSMLRWLYKLDHLYGLLLTFGLTLVVEGVFRSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGSSGQPYDVPSALSGATNLGFMFLPNYRAWVVVASLVVCFATWFVIEKTRLGAYLRAGT
HCCCCCCCCCCHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENPKLVEAFGINVPLMITLTYGFGVALAAFAGVLAAPVIQVSPLMGQPMIITVFAVVVIG
CCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
GMGSIMGSILTGLMLGVIEGLTRVFYPEASATVVFVIMALVLLVRPAGLFGKEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEIFGVPLPAMLSQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAMLAWMG
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYFGLPYWVMLVLAPLIVGLFGMAIERSMLRWLYKLDHLYGLLLTFGLTLVVEGVFRSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGSSGQPYDVPSALSGATNLGFMFLPNYRAWVVVASLVVCFATWFVIEKTRLGAYLRAGT
HCCCCCCCCCCHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENPKLVEAFGINVPLMITLTYGFGVALAAFAGVLAAPVIQVSPLMGQPMIITVFAVVVIG
CCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
GMGSIMGSILTGLMLGVIEGLTRVFYPEASATVVFVIMALVLLVRPAGLFGKEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]