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The map label for this gene is dsbD [H]

Identifier: 91785436

GI number: 91785436

Start: 4497687

End: 4499582

Strand: Reverse

Name: dsbD [H]

Synonym: Bxe_A0343

Alternate gene names: 91785436

Gene position: 4499582-4497687 (Counterclockwise)

Preceding gene: 91785437

Following gene: 91785433

Centisome position: 91.91

GC content: 64.61

Gene sequence:

>1896_bases
ATGTTTAACGGTATCGACCGGCGTGCGCGCAGGGCGCTGCGTGCTCTGTTCTTCCTGTTCGGTTGCCTTATCTTCGCCCA
GTTCGGCACCTCGGCTCGCGCTGCGGACGACTTCCTTGATCCCGCGGTCGCTTTCAAATTCAGCGCGACGGAGAAACCCG
GCGAAGTCGACGTGACCTACAAGATTGCGGATGGCTACTACATGTACCGGGAGCGCTTCGCCTTCGCGACGCGCAACGGC
ACGACGACGATCGGCGAGCCGCAACTACCGGCCGGCCACGTCAAGTTTGATCAGACCTTCAACAAGAACGTCGAGACGTA
TCGGAACGAGTTGACGATCCGCATTCCCGTTAAGCAGGCGGCCGGACCCTTCGATCTTGCGGTGACATCGCAAGGCTGTG
CGGATGCCGGCATCTGCTATCCGCCGATGGAGCGCGTGTACCACGTAAGCGGCGCGGCTCTGCAGGCAGCCGGCAGTCCA
GAAGCCGCCGGCGCCGGTGTTGCGCAACAATCGGAACAATCGGCTGTCGCGGGCAGCTCATGGTATGAGCGCGCCACCAG
CGCAGACTACGCGCAGTCGCTGCTGCAAGGCGGGGGCTTCTTTGCGATCGTCGGACTTTATTTCGTCGCCGGCGCCGTGC
TCAGTCTGCTTCCATGTTCGTATCCGATGATTCCTATTCTCTCGGCAATCATCATCGGGGAGGGCGCGAGAGTGACGCGT
GCCCGCGGATTCGCGTTGTCAGCCGCCTATGTGATCGGCATGGCGCTCGTGTACACGGCGCTTGGCATTGCCGCTGCGCT
GATCGGACAAAGTCTCGGCGCGTGGTTGCAAAATCCGTGGGTGCTCGGTGCCTTTGGCGTGCTGCTGACGGTTTTCGCGC
TGACCCTGATTGCCGGCCTCGACATCGCGCTTCCGCAGCGCTGGCAGGACGGCGTTTCGCGCGCGTCGGCGGGGCGCTCC
GGCGGCAAGTTTGCGGCCGTTGCCCTAATGGGCGCGCTGTCCGCGCTGGTGGTCGGCGCCTGCATGACCGCGCCGCTGTT
CGCGGTGCTGGCGTTCATTGCGCATACGGGCGACGCCGTGCTCGGCGGCGCAGCGCTATTTTCAATGGGACTGGGCTTGG
GCGTGCCGCTGCTCATTCTCGGTCTTGGCGCGGGCACGCTGTTGCCGCGCGCCGGCGCGTGGATGGACGGTGTCAAGGTG
TTCTTCGGTGTGGTGCTGCTCGCGGCGGCGCTGTGGATCGTCTGGCCGGTGCTCGGCGCAACTGCGACCATGCTTCTGAG
CGCCCTCTGGTTGCTGATCGCCGCAGCCTCGCTCGGCTTGTTCTCGGCGCCCGTCGCGCAGGCTTCCGTTTGGCGCCGGC
TGGGCCGCGGCATCGGCGCCGCGCTCGCGGTCTGGGCCGCAGTCCTGTTGGTCGGGCTGGCTGCGGGCTCATCCGATCCT
CTGCGCCCGCTCGCCGTTCTGGCGGCGCGCGGCGGGGAGGCGGGTGTGGCAGGTGTGGCGAACGCGTCGAATAAGCCTGA
CGGCGCGTCGCAGAGCGCTCTGACGTTTGTCCCGGTGCGCTCATCGACTGAACTCGACGAGGCCGTCAAAACGGCTGCAC
AGCCCGCTATGCTCGATTTTTACGCCGACTGGTGCGTCAGTTGCAAAGAGATGGAGAAGTTCACCTTCAGCGACCCGCGC
GTGCAGGCGAAATTGAAGCAGATGAATCTGTTGCGCGCCGACGTCACCGCAAACAACGCCGACGATCAAACGCTGCTTAA
ACGCTTCAGCCTGTTCGGGCCGCCGGGGATCATATTCTTCGATCAGGGTGGCAAGGAAGTGCTGCGTGTGGTGGGATATG
AGTCGGCGGATAAATTCTTGCGCAGCCTGGATCGGGCGCGTGGGACCGGGGCCTAA

Upstream 100 bases:

>100_bases
GCGCACCATCCTTACGACACGCCGGAGATCCTCTCCTGGCAAGCGACGGCATCTGCCGCGTACGGCCAGTGGATCACTGC
TGAAACCCAACGTCCCCTCC

Downstream 100 bases:

>100_bases
CTGAGGACGAGTGTCCTCTATCGTCCGCGCCTAGTGTCCGAAGCTGATGAATGTCGAGCGCCACCCGCGGTCAAACGACG
CCTGACCGCAACTGAACAAA

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MFNGIDRRARRALRALFFLFGCLIFAQFGTSARAADDFLDPAVAFKFSATEKPGEVDVTYKIADGYYMYRERFAFATRNG
TTTIGEPQLPAGHVKFDQTFNKNVETYRNELTIRIPVKQAAGPFDLAVTSQGCADAGICYPPMERVYHVSGAALQAAGSP
EAAGAGVAQQSEQSAVAGSSWYERATSADYAQSLLQGGGFFAIVGLYFVAGAVLSLLPCSYPMIPILSAIIIGEGARVTR
ARGFALSAAYVIGMALVYTALGIAAALIGQSLGAWLQNPWVLGAFGVLLTVFALTLIAGLDIALPQRWQDGVSRASAGRS
GGKFAAVALMGALSALVVGACMTAPLFAVLAFIAHTGDAVLGGAALFSMGLGLGVPLLILGLGAGTLLPRAGAWMDGVKV
FFGVVLLAAALWIVWPVLGATATMLLSALWLLIAAASLGLFSAPVAQASVWRRLGRGIGAALAVWAAVLLVGLAAGSSDP
LRPLAVLAARGGEAGVAGVANASNKPDGASQSALTFVPVRSSTELDEAVKTAAQPAMLDFYADWCVSCKEMEKFTFSDPR
VQAKLKQMNLLRADVTANNADDQTLLKRFSLFGPPGIIFFDQGGKEVLRVVGYESADKFLRSLDRARGTGA

Sequences:

>Translated_631_residues
MFNGIDRRARRALRALFFLFGCLIFAQFGTSARAADDFLDPAVAFKFSATEKPGEVDVTYKIADGYYMYRERFAFATRNG
TTTIGEPQLPAGHVKFDQTFNKNVETYRNELTIRIPVKQAAGPFDLAVTSQGCADAGICYPPMERVYHVSGAALQAAGSP
EAAGAGVAQQSEQSAVAGSSWYERATSADYAQSLLQGGGFFAIVGLYFVAGAVLSLLPCSYPMIPILSAIIIGEGARVTR
ARGFALSAAYVIGMALVYTALGIAAALIGQSLGAWLQNPWVLGAFGVLLTVFALTLIAGLDIALPQRWQDGVSRASAGRS
GGKFAAVALMGALSALVVGACMTAPLFAVLAFIAHTGDAVLGGAALFSMGLGLGVPLLILGLGAGTLLPRAGAWMDGVKV
FFGVVLLAAALWIVWPVLGATATMLLSALWLLIAAASLGLFSAPVAQASVWRRLGRGIGAALAVWAAVLLVGLAAGSSDP
LRPLAVLAARGGEAGVAGVANASNKPDGASQSALTFVPVRSSTELDEAVKTAAQPAMLDFYADWCVSCKEMEKFTFSDPR
VQAKLKQMNLLRADVTANNADDQTLLKRFSLFGPPGIIFFDQGGKEVLRVVGYESADKFLRSLDRARGTGA
>Mature_631_residues
MFNGIDRRARRALRALFFLFGCLIFAQFGTSARAADDFLDPAVAFKFSATEKPGEVDVTYKIADGYYMYRERFAFATRNG
TTTIGEPQLPAGHVKFDQTFNKNVETYRNELTIRIPVKQAAGPFDLAVTSQGCADAGICYPPMERVYHVSGAALQAAGSP
EAAGAGVAQQSEQSAVAGSSWYERATSADYAQSLLQGGGFFAIVGLYFVAGAVLSLLPCSYPMIPILSAIIIGEGARVTR
ARGFALSAAYVIGMALVYTALGIAAALIGQSLGAWLQNPWVLGAFGVLLTVFALTLIAGLDIALPQRWQDGVSRASAGRS
GGKFAAVALMGALSALVVGACMTAPLFAVLAFIAHTGDAVLGGAALFSMGLGLGVPLLILGLGAGTLLPRAGAWMDGVKV
FFGVVLLAAALWIVWPVLGATATMLLSALWLLIAAASLGLFSAPVAQASVWRRLGRGIGAALAVWAAVLLVGLAAGSSDP
LRPLAVLAARGGEAGVAGVANASNKPDGASQSALTFVPVRSSTELDEAVKTAAQPAMLDFYADWCVSCKEMEKFTFSDPR
VQAKLKQMNLLRADVTANNADDQTLLKRFSLFGPPGIIFFDQGGKEVLRVVGYESADKFLRSLDRARGTGA

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=624, Percent_Identity=34.2948717948718, Blast_Score=313, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 65950; Mature: 65950

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNGIDRRARRALRALFFLFGCLIFAQFGTSARAADDFLDPAVAFKFSATEKPGEVDVTY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHEEEEECCCCCCCEEEEE
KIADGYYMYRERFAFATRNGTTTIGEPQLPAGHVKFDQTFNKNVETYRNELTIRIPVKQA
EECCCHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECHHHCCCHHHHHCCEEEEEEHHHC
AGPFDLAVTSQGCADAGICYPPMERVYHVSGAALQAAGSPEAAGAGVAQQSEQSAVAGSS
CCCCEEEEECCCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCH
WYERATSADYAQSLLQGGGFFAIVGLYFVAGAVLSLLPCSYPMIPILSAIIIGEGARVTR
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHH
ARGFALSAAYVIGMALVYTALGIAAALIGQSLGAWLQNPWVLGAFGVLLTVFALTLIAGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
DIALPQRWQDGVSRASAGRSGGKFAAVALMGALSALVVGACMTAPLFAVLAFIAHTGDAV
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LGGAALFSMGLGLGVPLLILGLGAGTLLPRAGAWMDGVKVFFGVVLLAAALWIVWPVLGA
HHHHHHHHHHHCCCHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATMLLSALWLLIAAASLGLFSAPVAQASVWRRLGRGIGAALAVWAAVLLVGLAAGSSDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
LRPLAVLAARGGEAGVAGVANASNKPDGASQSALTFVPVRSSTELDEAVKTAAQPAMLDF
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHH
YADWCVSCKEMEKFTFSDPRVQAKLKQMNLLRADVTANNADDQTLLKRFSLFGPPGIIFF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEE
DQGGKEVLRVVGYESADKFLRSLDRARGTGA
CCCCHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNGIDRRARRALRALFFLFGCLIFAQFGTSARAADDFLDPAVAFKFSATEKPGEVDVTY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHEEEEECCCCCCCEEEEE
KIADGYYMYRERFAFATRNGTTTIGEPQLPAGHVKFDQTFNKNVETYRNELTIRIPVKQA
EECCCHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECHHHCCCHHHHHCCEEEEEEHHHC
AGPFDLAVTSQGCADAGICYPPMERVYHVSGAALQAAGSPEAAGAGVAQQSEQSAVAGSS
CCCCEEEEECCCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCH
WYERATSADYAQSLLQGGGFFAIVGLYFVAGAVLSLLPCSYPMIPILSAIIIGEGARVTR
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHH
ARGFALSAAYVIGMALVYTALGIAAALIGQSLGAWLQNPWVLGAFGVLLTVFALTLIAGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
DIALPQRWQDGVSRASAGRSGGKFAAVALMGALSALVVGACMTAPLFAVLAFIAHTGDAV
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LGGAALFSMGLGLGVPLLILGLGAGTLLPRAGAWMDGVKVFFGVVLLAAALWIVWPVLGA
HHHHHHHHHHHCCCHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATMLLSALWLLIAAASLGLFSAPVAQASVWRRLGRGIGAALAVWAAVLLVGLAAGSSDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
LRPLAVLAARGGEAGVAGVANASNKPDGASQSALTFVPVRSSTELDEAVKTAAQPAMLDF
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHH
YADWCVSCKEMEKFTFSDPRVQAKLKQMNLLRADVTANNADDQTLLKRFSLFGPPGIIFF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEE
DQGGKEVLRVVGYESADKFLRSLDRARGTGA
CCCCHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]