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The map label for this gene is hisC [H]

Identifier: 91785380

GI number: 91785380

Start: 4437321

End: 4438391

Strand: Reverse

Name: hisC [H]

Synonym: Bxe_A0399

Alternate gene names: 91785380

Gene position: 4438391-4437321 (Counterclockwise)

Preceding gene: 91785381

Following gene: 91785379

Centisome position: 90.66

GC content: 64.24

Gene sequence:

>1071_bases
ATGACGACACCTCAAGACATCATCCGCCGCGACGTGCTCGCGATGACGAGCTATCCGGTTCCGGACGCCACGGGCTATAT
CAAGCTCGACGCGATGGAAAATCCGTTCCCGCTGCCGCCGGTGCTGGCCGCGCATCTGGGCGAGCACCTCGCCGGCGTCG
CGCTGAACCGCTATCCGGCGCCGCGTCCGGATGCGCTGATCGAGAAGATCAAGCGTGTGATGCAGGTGCCGCCCGGCTGC
GACGTGCTGCTCGGCAACGGCTCGGATGAAATCATCAGCATGGTGTCGGTCGCGTGCGCGCAGCCGGGCGCCAAGGTGCT
CGCGCCGGTGCCGGGCTTCGTGATGTACCAGATGTCGGCGAAGCTGGCGAATCTCGAGTTCGTCGGCGTGCCGCTGAAAG
CGGATTTCACGCTCGATACCGAAGCGATGCTGGCCGCCATCGCCGAGCACCAGCCGGCGATCATCTACCTCGCGTATCCG
AACAACCCGACCGGGACGCTGTTCGACGACGCCGACATGGAGCGCATCATCGCCGCGGCCAGCAAGAGCCTCGTGGTGAT
CGACGAGGCCTACCAGCCGTTCGCGCAGCAAAGCTGGCTGCCGCGCGCCGACGCGTTCGACAACGTGGTGGTGATGCGCA
CGGTGTCCAAGCTCGGCCTGGCCGGAATCCGTCTCGGGTATCTGGTCGGCAAACCGGGCTGGCTGACGGAATTCGACAAG
GTGCGGCCGCCGTACAACACCAACGTGCTCACGCAGGCCGCCGCGGATTTCCTGCTCGACCACGTCGACGTGCTCGATTC
TCAAGCCGCGCAATTGCGCGAAGAACGCACGAAACTCGCGCACGCGATCGCCCAGTTGCCGGGCGCCGAAGTGTTCCCGA
GCGCCGGCAACTTCCTGCTGGTGCGTGTGCCGGACGCGTCGGTCCTGTTCGAAACGCTGCTGGCGGCGCGGGTTTTGATC
AAAAACGTGAGTAAAATGCATCCGTTGCTGGCCAATTGCGTGCGTTTGACCGTCGGTTCGCCCGAAGAAAATGCGCAATT
GCTGGCCGCACTGAAGCTCGTATTGCATTGA

Upstream 100 bases:

>100_bases
TTCCACGTTAAATACAGACAAGACAAACAGACCAACCTCTGGCGGCCAGCATGCCGCCGACGCCGGGCTTGCGTTCCCTT
GCGGCCCGCTCCACCGACCT

Downstream 100 bases:

>100_bases
AGGCGTGCCGAATGGCCGCGCAAGCGCTTTTCCTCATCACGGGATAGCGCGCGCAGCCCTGCCGTTTTTCCATCCCACAT
ACCTATCGCTTTCTAGCCAG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTTPQDIIRRDVLAMTSYPVPDATGYIKLDAMENPFPLPPVLAAHLGEHLAGVALNRYPAPRPDALIEKIKRVMQVPPGC
DVLLGNGSDEIISMVSVACAQPGAKVLAPVPGFVMYQMSAKLANLEFVGVPLKADFTLDTEAMLAAIAEHQPAIIYLAYP
NNPTGTLFDDADMERIIAAASKSLVVIDEAYQPFAQQSWLPRADAFDNVVVMRTVSKLGLAGIRLGYLVGKPGWLTEFDK
VRPPYNTNVLTQAAADFLLDHVDVLDSQAAQLREERTKLAHAIAQLPGAEVFPSAGNFLLVRVPDASVLFETLLAARVLI
KNVSKMHPLLANCVRLTVGSPEENAQLLAALKLVLH

Sequences:

>Translated_356_residues
MTTPQDIIRRDVLAMTSYPVPDATGYIKLDAMENPFPLPPVLAAHLGEHLAGVALNRYPAPRPDALIEKIKRVMQVPPGC
DVLLGNGSDEIISMVSVACAQPGAKVLAPVPGFVMYQMSAKLANLEFVGVPLKADFTLDTEAMLAAIAEHQPAIIYLAYP
NNPTGTLFDDADMERIIAAASKSLVVIDEAYQPFAQQSWLPRADAFDNVVVMRTVSKLGLAGIRLGYLVGKPGWLTEFDK
VRPPYNTNVLTQAAADFLLDHVDVLDSQAAQLREERTKLAHAIAQLPGAEVFPSAGNFLLVRVPDASVLFETLLAARVLI
KNVSKMHPLLANCVRLTVGSPEENAQLLAALKLVLH
>Mature_355_residues
TTPQDIIRRDVLAMTSYPVPDATGYIKLDAMENPFPLPPVLAAHLGEHLAGVALNRYPAPRPDALIEKIKRVMQVPPGCD
VLLGNGSDEIISMVSVACAQPGAKVLAPVPGFVMYQMSAKLANLEFVGVPLKADFTLDTEAMLAAIAEHQPAIIYLAYPN
NPTGTLFDDADMERIIAAASKSLVVIDEAYQPFAQQSWLPRADAFDNVVVMRTVSKLGLAGIRLGYLVGKPGWLTEFDKV
RPPYNTNVLTQAAADFLLDHVDVLDSQAAQLREERTKLAHAIAQLPGAEVFPSAGNFLLVRVPDASVLFETLLAARVLIK
NVSKMHPLLANCVRLTVGSPEENAQLLAALKLVLH

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=363, Percent_Identity=30.0275482093664, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788722, Length=265, Percent_Identity=25.2830188679245, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322075, Length=367, Percent_Identity=28.8828337874659, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38484; Mature: 38353

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPQDIIRRDVLAMTSYPVPDATGYIKLDAMENPFPLPPVLAAHLGEHLAGVALNRYPA
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PRPDALIEKIKRVMQVPPGCDVLLGNGSDEIISMVSVACAQPGAKVLAPVPGFVMYQMSA
CCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
KLANLEFVGVPLKADFTLDTEAMLAAIAEHQPAIIYLAYPNNPTGTLFDDADMERIIAAA
HHCCEEEEEECEECCCEECHHHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHHHHHHHC
SKSLVVIDEAYQPFAQQSWLPRADAFDNVVVMRTVSKLGLAGIRLGYLVGKPGWLTEFDK
CCCEEEEEHHHCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHH
VRPPYNTNVLTQAAADFLLDHVDVLDSQAAQLREERTKLAHAIAQLPGAEVFPSAGNFLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
VRVPDASVLFETLLAARVLIKNVSKMHPLLANCVRLTVGSPEENAQLLAALKLVLH
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
TTPQDIIRRDVLAMTSYPVPDATGYIKLDAMENPFPLPPVLAAHLGEHLAGVALNRYPA
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PRPDALIEKIKRVMQVPPGCDVLLGNGSDEIISMVSVACAQPGAKVLAPVPGFVMYQMSA
CCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
KLANLEFVGVPLKADFTLDTEAMLAAIAEHQPAIIYLAYPNNPTGTLFDDADMERIIAAA
HHCCEEEEEECEECCCEECHHHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHHHHHHHC
SKSLVVIDEAYQPFAQQSWLPRADAFDNVVVMRTVSKLGLAGIRLGYLVGKPGWLTEFDK
CCCEEEEEHHHCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHH
VRPPYNTNVLTQAAADFLLDHVDVLDSQAAQLREERTKLAHAIAQLPGAEVFPSAGNFLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
VRVPDASVLFETLLAARVLIKNVSKMHPLLANCVRLTVGSPEENAQLLAALKLVLH
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12754231 [H]