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The map label for this gene is ftsW [H]

Identifier: 91785294

GI number: 91785294

Start: 4342954

End: 4344234

Strand: Reverse

Name: ftsW [H]

Synonym: Bxe_A0485

Alternate gene names: 91785294

Gene position: 4344234-4342954 (Counterclockwise)

Preceding gene: 91785295

Following gene: 91785293

Centisome position: 88.73

GC content: 64.25

Gene sequence:

>1281_bases
ATGAGCTGGTCGGAACGTTTCGGTTCGCGTCAGGCTGCAGCCAGCGACGCAGGCGGTTTGGGCGGCGCGGGCCGGGTCGG
CGGCCGCACGGGCGGCGGCAGCGGTCTCGCGAGCGCCGTCAACGGCGTGCGTCCGCTGCGCTCGCGCATGCTGGACTACG
ATCACTCGCTGCTGTGGGTAGTGGTCGCGCTGCTCGGACTCGGCGTGGTGATGGTGTATTCGGCGTCGATCGCGATGCCC
GATTCGCCGAAATACGCGTCGTATCGCGACTACGCCTTCCTCGTGCGCCAGATCATTTTCGTGGTGATGGGCTCGGTAAT
CGGCGTCGTGTCGTTCCGCATTCCGATCGCCACGTGGGACAAGTACGCGCCAAAGCTGTTTCTGATTTCGCTGGCCGCGC
TGGTGATCGTGCTGATCCCGCACGTCGGCAAGGGCGTGAACGGCGCGCGCCGCTGGATTCCGCTCGGCATCACGAACATG
CAGCCGTCGGAAATCATGAAGCTCGCGGTAACGATTTACGCCGCGAACTACACGGTGCGCAAGCAGGAATACATGCACAG
CTTCGCCAAAGGCTTTTTGCCGATGGCAGTCGCCGTGGGGCTCGTCGGCGCGTTGCTGCTGCTCGAACCGGACATGGGCG
CGTTCATGGTGATCGCGGCGATCGCAATGGGCGTGCTGTTTCTCGGCGGCGTGAACGGCAAGCTGTTCGGCGGCCTCGTC
GCCACCGCGGTCGGCACGTTCAGTTTGCTGGTGTGGGCGTCGCCGTGGCGTCGCGAGCGGATTTTCGCGTACCTCGATCC
GTGGGACGACCGTTACGCCCAGGGCAAGGCCTATCAATTGACGCACTCGCTGATCGCGTTCGGCCGCGGCGAGTGGTTCG
GCGTGGGACTCGGCGGCAGCGTCGAGAAGCTCAACTATCTGCCGGAAGCGCATACCGACTTCATCCTCGCGGTGATCGGC
GAGGAGCTGGGTTTTGTCGGCGTGCTGGTCGTGATCCTGATGTTCTACTGGATCGTGCGCCGCTCGTTCGAGATCGGCCG
CCAGGCGCTCGCACTCGACCGCACGTTCGCGGGTCTGGTCGCGAAGGGCGTCGGCATCTGGTTCGGCGCGCAGACCTTCA
TCAACATGGGCGTGAACCTCGGTTTGCTGCCGACCAAAGGTCTTACGTTGCCGCTCGTCAGTTACGGCGGCTCGGGCATT
TTGCTGAACTGCGTCGCGGTGGCTGTGCTGATGCGCGTCGACTATGAGAACCGGGTGCTCATGCGCGGAGGGAAAGTATG
A

Upstream 100 bases:

>100_bases
CGGCCTGCGCGAGCTTCGACATGTTCAAGGGTTACGCGCACCGCGCCGCGGTGTTCCGCGGCACGGTGGAAGAGATCGCA
GCCGAACGGGGGACGATGAT

Downstream 100 bases:

>100_bases
CCGCTCTGCCGCAACGCACGCTGATGGTGATGGCCGGTGGCACCGGGGGACACGTGTTCCCGGGGCTCGCGGTCGCTCAT
CTGATGCAGGCGTGGGGCTG

Product: cell division transmembrane protein, FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSWSERFGSRQAAASDAGGLGGAGRVGGRTGGGSGLASAVNGVRPLRSRMLDYDHSLLWVVVALLGLGVVMVYSASIAMP
DSPKYASYRDYAFLVRQIIFVVMGSVIGVVSFRIPIATWDKYAPKLFLISLAALVIVLIPHVGKGVNGARRWIPLGITNM
QPSEIMKLAVTIYAANYTVRKQEYMHSFAKGFLPMAVAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLFGGLV
ATAVGTFSLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIG
EELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLVAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGI
LLNCVAVAVLMRVDYENRVLMRGGKV

Sequences:

>Translated_426_residues
MSWSERFGSRQAAASDAGGLGGAGRVGGRTGGGSGLASAVNGVRPLRSRMLDYDHSLLWVVVALLGLGVVMVYSASIAMP
DSPKYASYRDYAFLVRQIIFVVMGSVIGVVSFRIPIATWDKYAPKLFLISLAALVIVLIPHVGKGVNGARRWIPLGITNM
QPSEIMKLAVTIYAANYTVRKQEYMHSFAKGFLPMAVAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLFGGLV
ATAVGTFSLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIG
EELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLVAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGI
LLNCVAVAVLMRVDYENRVLMRGGKV
>Mature_425_residues
SWSERFGSRQAAASDAGGLGGAGRVGGRTGGGSGLASAVNGVRPLRSRMLDYDHSLLWVVVALLGLGVVMVYSASIAMPD
SPKYASYRDYAFLVRQIIFVVMGSVIGVVSFRIPIATWDKYAPKLFLISLAALVIVLIPHVGKGVNGARRWIPLGITNMQ
PSEIMKLAVTIYAANYTVRKQEYMHSFAKGFLPMAVAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLFGGLVA
TAVGTFSLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIGE
ELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLVAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGIL
LNCVAVAVLMRVDYENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=368, Percent_Identity=43.4782608695652, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI1786853, Length=341, Percent_Identity=33.1378299120235, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45851; Mature: 45720

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
SWSERFGSRQAAASDAGGLGGAGRVGGRTGGGSGLASAVNGVRPLRSRMLDYDHSLLWV
CCHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
VVALLGLGVVMVYSASIAMPDSPKYASYRDYAFLVRQIIFVVMGSVIGVVSFRIPIATWD
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHH
KYAPKLFLISLAALVIVLIPHVGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTVR
HHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHEECCCCHH
KQEYMHSFAKGFLPMAVAVGLVGALLLLEPDMGAFMVIAAIAMGVLFLGGVNGKLFGGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
ATAVGTFSLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGS
HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHCCCCEEEECCCCC
VEKLNYLPEAHTDFILAVIGEELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCVAVAVLMRVDYENRVL
HHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEE
MRGGKV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]