BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

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The map label for this gene is fabG [H]

Identifier: 91785230

GI number: 91785230

Start: 4276532

End: 4277332

Strand: Reverse

Name: fabG [H]

Synonym: Bxe_A0549

Alternate gene names: 91785230

Gene position: 4277332-4276532 (Counterclockwise)

Preceding gene: 91785231

Following gene: 91785229

Centisome position: 87.37

GC content: 65.04

Gene sequence:

>801_bases
ATGTCGTCTCCGGCCAATGCAAACGCCCGTCTCGCGGAGAGCGCCTTCGCCCGCTATCCGAGTCTTGTCGACCGCACGGT
GTTGATCACGGGCGGCGCGACTGGCATCGGCGCGTCGTTCGTCGAGCATTTCGCGGCGCAAGGCGCGCGTGTCGCGTTCT
TCGACATTGACACGAGCGCCGGTGAAGCGCTCGCCGACGAACTCGGCGACTCGAAGCACAAGCCGCTGTTTCTGCCGTGT
GACCTGACCGACATCGACGCGCTGCAAAAAGCAATCGCCGACGTGAAGGCCGCCCTCGGTCCGATCCAGGTGCTGGTGAA
CAACGCCGCGAACGACAAGCGCCACACCATCGGCGAAGTCACGCGCGAGTCGTTCGACGCGGGCATCGCGGTGAATATCC
GCCACCAGTTCTTCGCGGCGCAGGCGGTGATGGACGACATGAAGGCGGCCAACGGCGGCTCGATCATCAACCTCGGTTCG
ATCAGCTGGATGCTGAAGAACGGCGGCTATCCGGTGTACGTGATGTCGAAGGCGGCGGTGCAGGGTTTGACGCGTGGTCT
CGCGCGCGACCTCGGCCAGTTCAATATCCGCGTCAATACGCTGGTGCCGGGCTGGGTGATGACCGGGAAGCAGAAGCGCT
TGTGGCTCGACGACGCCGGCCGCCGGTCGATCAAGGAAGGGCAGTGTATCGACGCCGAGCTGGAACCGGCCGATCTCGCC
CGCATGGCGCTCTTCCTCGCCGCCGACGACAGCAGGATGATCACGGCGCAGGACCTCATCGTGGACGGAGGCTGGGCGTG
A

Upstream 100 bases:

>100_bases
CGCGATCCTGCTCGCCGCCGTGCTGCTCGACCAGTTGAAGAATCGCGGATCACGAGATTAAATCCGCGACCAGCTTACTT
GCTCTAAAAGGAATCGAACG

Downstream 100 bases:

>100_bases
GTGCGAATGGTTCGCCAGTCGCGGCGGCCAGGCGCGCCGCGCTGCTGCTCGACACGAAATGCATGCTCGGCGAAGGCGCG
ACATGGTGCGCGCAAACCGG

Product: putative short-chain dehydrogenase/reductase, FabG-like

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSSPANANARLAESAFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDTSAGEALADELGDSKHKPLFLPC
DLTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEVTRESFDAGIAVNIRHQFFAAQAVMDDMKAANGGSIINLGS
ISWMLKNGGYPVYVMSKAAVQGLTRGLARDLGQFNIRVNTLVPGWVMTGKQKRLWLDDAGRRSIKEGQCIDAELEPADLA
RMALFLAADDSRMITAQDLIVDGGWA

Sequences:

>Translated_266_residues
MSSPANANARLAESAFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDTSAGEALADELGDSKHKPLFLPC
DLTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEVTRESFDAGIAVNIRHQFFAAQAVMDDMKAANGGSIINLGS
ISWMLKNGGYPVYVMSKAAVQGLTRGLARDLGQFNIRVNTLVPGWVMTGKQKRLWLDDAGRRSIKEGQCIDAELEPADLA
RMALFLAADDSRMITAQDLIVDGGWA
>Mature_265_residues
SSPANANARLAESAFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDTSAGEALADELGDSKHKPLFLPCD
LTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEVTRESFDAGIAVNIRHQFFAAQAVMDDMKAANGGSIINLGSI
SWMLKNGGYPVYVMSKAAVQGLTRGLARDLGQFNIRVNTLVPGWVMTGKQKRLWLDDAGRRSIKEGQCIDAELEPADLAR
MALFLAADDSRMITAQDLIVDGGWA

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.8880308880309, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=34.136546184739, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=32.5301204819277, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=29.2181069958848, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=27.9245283018868, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI31542939, Length=192, Percent_Identity=31.7708333333333, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=31.8181818181818, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=28.3261802575107, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=233, Percent_Identity=29.1845493562232, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=25.7692307692308, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.0155440414508, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI210032110, Length=211, Percent_Identity=28.9099526066351, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=31.1764705882353, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI83715985, Length=199, Percent_Identity=30.6532663316583, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=27.4193548387097, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=23.7547892720307, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=31.5573770491803, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=30.7086614173228, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=30.9917355371901, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.6747967479675, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=28.968253968254, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=31.1203319502075, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=28.0632411067194, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=28.1124497991968, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=29.5546558704453, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367175, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=25.1937984496124, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=31.7073170731707, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=32.520325203252, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=29.8850574712644, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=34.010152284264, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.9693486590038, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=30.5970149253731, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=28.2442748091603, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=28.7179487179487, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.4354838709677, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=27.5193798449612, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=28.8389513108614, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=28.7878787878788, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.030303030303, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.9245283018868, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.8195488721804, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=26.953125, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.6259541984733, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=24.5901639344262, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=25.1336898395722, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=25.1336898395722, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=23.4126984126984, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=26.5625, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=27.1062271062271, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=23.6842105263158, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=28.4, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=27.3809523809524, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=27.7551020408163, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640492, Length=202, Percent_Identity=28.2178217821782, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17737361, Length=193, Percent_Identity=32.1243523316062, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=32.48730964467, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=247, Percent_Identity=29.9595141700405, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=24.0963855421687, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=25.130890052356, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28376; Mature: 28244

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPANANARLAESAFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDTSA
CCCCCCCCHHHHHHHHHHCHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCC
GEALADELGDSKHKPLFLPCDLTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEV
HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
TRESFDAGIAVNIRHQFFAAQAVMDDMKAANGGSIINLGSISWMLKNGGYPVYVMSKAAV
HHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCEEEEEECHHHH
QGLTRGLARDLGQFNIRVNTLVPGWVMTGKQKRLWLDDAGRRSIKEGQCIDAELEPADLA
HHHHHHHHHHHHHEEEEEEEECCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHH
RMALFLAADDSRMITAQDLIVDGGWA
HHHHEEECCCCCEEEEHHEEECCCCC
>Mature Secondary Structure 
SSPANANARLAESAFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDTSA
CCCCCCCHHHHHHHHHHCHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCC
GEALADELGDSKHKPLFLPCDLTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEV
HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
TRESFDAGIAVNIRHQFFAAQAVMDDMKAANGGSIINLGSISWMLKNGGYPVYVMSKAAV
HHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCEEEEEECHHHH
QGLTRGLARDLGQFNIRVNTLVPGWVMTGKQKRLWLDDAGRRSIKEGQCIDAELEPADLA
HHHHHHHHHHHHHEEEEEEEECCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHH
RMALFLAADDSRMITAQDLIVDGGWA
HHHHEEECCCCCEEEEHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]