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The map label for this gene is edd [H]

Identifier: 91785190

GI number: 91785190

Start: 4224745

End: 4226649

Strand: Reverse

Name: edd [H]

Synonym: Bxe_A0589

Alternate gene names: 91785190

Gene position: 4226649-4224745 (Counterclockwise)

Preceding gene: 91785192

Following gene: 91785189

Centisome position: 86.33

GC content: 65.14

Gene sequence:

>1905_bases
ATGGTTTCCCCGCATTCGCAATTGTTGAAGGTCACGCAACGCGTGGTCGAGCGCAGCAAGCCTACGCGCGAGGCGTATCT
GGCCCGCATCGAGCAGGCGCAAGGCCGCTTCCCGGCGCGCGGTGCACTCTCGTGCGCCAATCTGGCCCACGGTTTCGCCG
GGCTCGAAGGCAACGACAAGCTCGTCATCAAGCAGATTCGCGAGCCGAACATCGGCATCGTGTCCTCGTACAACGAAATG
TTGTCGGCCCACGCGCCGTACAAAAACTACCCGGACATCATCAAGCAGGCCGCGCGTGAAAACGGCGGCGTCGCCCAATT
CGCGGGCGGCGTACCGGCCATGTGCGACGGCGTCACGCAAGGCAACGCGGGCATGGAACTGTCGCTGTTCTCGCGCGAAG
TGATCGCAATGAGCACGGCGGTCGCGCTGACGCACAACATGTTCGACGCGGCACTGTGCTTAGGTATTTGCGACAAGATC
GTGCCGGGCTTGCTGATCGGCGCGCTGCAATTCGGCCATCTGCCGACCATCTTCGTGCCGGCCGGCCCGATGGGCAGCGG
CCTGTCCAACGACGACAAAGCCAAAACGCGCCAGCTCTTCGCCACCGGCCAGTGCGGCCGCGACGCGCTGCTCGAAGCGG
AAGCCGCCGCGTATCACAGCCACGGCACCTGCACGTTCTACGGTACGGCCAACAGCAATCAGATGCTGATGGAAGTGATG
GGTTTGCATCTGCCGAGTTCGGCTTTCGTGCATCCGCATACGCCGCTGCGCGACGCATTGACCGCGCAGGCCGCGCGCCG
CGTGCTCGATCTCACGGTCGAGCGCGGCAACTACACGCCGATCGGACATGTGGTCGACGAGAAAGCGATCGTCAACGGCA
TCGTCGCGTTGCTGGCGACAGGCGGCTCGACCAACCACACGCTGCACCTGGTGGCGATTGCTCGCGCGGCGGGCATCGTG
ATCGACTGGGACGACTTCGACGCGCTGTCGCAAGCCGTGCCGCTGCTCGCGAAGATCTATCCGAACGGCAAGGCCGACGT
GAACCACTTCCACGCAGCCGGCGGCGTCGCCTTCCTGGTACGCAACCTGCTGGAAGGCGGCTTGCTGCACGAAGACGTCA
ACACGGTCGCGGGCAAGGGACTCAAGCACTACACCGAAGAGCCGAAGCTGATCGACGGCAAGCTGCAATGGGTGCCGGGC
GCCGAAGCCAGCGAAGACACGGCGGTGCTGCGCGGCATCAAGGAGCCGTTCCAGCCGGACGGCGGTTTGCGTCTGATGCA
GGGCAAGCTCGGCCGCGGCGTGATCAAGATTTCCGCGGTGGCGGCGCAGCATCGCAAGGTGAAGGCGCCGGCGATCGTGT
TCGATTCGCAGGAAGCCGTGCAGGAAGCGTTCGACAAAGGCGAGCTGAAACGCGACTTCATCGCCGTGGTGCGCTTCCAG
GGCGCGCGGGCAAACGGCATGCCCGAGTTGCATCGTTTGACGCCGCTGCTCGGTGTGTTGCAGGATCAAGGTTTCCACGT
TGCGCTGGTCACGGACGGCCGTATGTCCGGCGCATCGGGCAAGGTGCCCGCGGTGATTCACCTGTCGCCGGAAGCCTTGC
TGCAAGGCCCGATCGGCAAGGTGCGCACGGGCGACATGCTGGTGATCGACGCCGAAGCCGGTGTGCTCGACATCGAGATC
GACGCGGCGGAATGGGCCGCGCGGCCGAATGCCGTGCCGCTGCATCAGGCGGAAAACGAAGTCGGCTTCGGCCGCGAACT
GTTCGGTGTGTTCCGCGCGGCGGCGGCGCCGGCGGAGCAGGGTGCGTCGGTATTCGGCGCGATGGTGGGCGAGCGTTCGG
CGCATCACGGCGAAGCGGCCGAAGCGCACACCGGCAAACATACAAGCACCACTCAAGCCAGCTAA

Upstream 100 bases:

>100_bases
GTTTTTCTACTAAGATGGCGGCGTCGACTGATCCGACATCCCCGCTATACCTGCCTGGCCTCACGCGCGCACGCCCGCCG
CCAGCGACGAAGGAGCTCCG

Downstream 100 bases:

>100_bases
GCGCTGCAGAACAAGGAGTCTGACTATGACGTCGAAAACAGTAAGCGATATCGTGCGCCTCGGCCCGGTGATTCCGGTGC
TCGCGTTCGACTCGGTCGAA

Product: phosphogluconate dehydratase

Products: NA

Alternate protein names: 6-phosphogluconate dehydratase [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MVSPHSQLLKVTQRVVERSKPTREAYLARIEQAQGRFPARGALSCANLAHGFAGLEGNDKLVIKQIREPNIGIVSSYNEM
LSAHAPYKNYPDIIKQAARENGGVAQFAGGVPAMCDGVTQGNAGMELSLFSREVIAMSTAVALTHNMFDAALCLGICDKI
VPGLLIGALQFGHLPTIFVPAGPMGSGLSNDDKAKTRQLFATGQCGRDALLEAEAAAYHSHGTCTFYGTANSNQMLMEVM
GLHLPSSAFVHPHTPLRDALTAQAARRVLDLTVERGNYTPIGHVVDEKAIVNGIVALLATGGSTNHTLHLVAIARAAGIV
IDWDDFDALSQAVPLLAKIYPNGKADVNHFHAAGGVAFLVRNLLEGGLLHEDVNTVAGKGLKHYTEEPKLIDGKLQWVPG
AEASEDTAVLRGIKEPFQPDGGLRLMQGKLGRGVIKISAVAAQHRKVKAPAIVFDSQEAVQEAFDKGELKRDFIAVVRFQ
GARANGMPELHRLTPLLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLQGPIGKVRTGDMLVIDAEAGVLDIEI
DAAEWAARPNAVPLHQAENEVGFGRELFGVFRAAAAPAEQGASVFGAMVGERSAHHGEAAEAHTGKHTSTTQAS

Sequences:

>Translated_634_residues
MVSPHSQLLKVTQRVVERSKPTREAYLARIEQAQGRFPARGALSCANLAHGFAGLEGNDKLVIKQIREPNIGIVSSYNEM
LSAHAPYKNYPDIIKQAARENGGVAQFAGGVPAMCDGVTQGNAGMELSLFSREVIAMSTAVALTHNMFDAALCLGICDKI
VPGLLIGALQFGHLPTIFVPAGPMGSGLSNDDKAKTRQLFATGQCGRDALLEAEAAAYHSHGTCTFYGTANSNQMLMEVM
GLHLPSSAFVHPHTPLRDALTAQAARRVLDLTVERGNYTPIGHVVDEKAIVNGIVALLATGGSTNHTLHLVAIARAAGIV
IDWDDFDALSQAVPLLAKIYPNGKADVNHFHAAGGVAFLVRNLLEGGLLHEDVNTVAGKGLKHYTEEPKLIDGKLQWVPG
AEASEDTAVLRGIKEPFQPDGGLRLMQGKLGRGVIKISAVAAQHRKVKAPAIVFDSQEAVQEAFDKGELKRDFIAVVRFQ
GARANGMPELHRLTPLLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLQGPIGKVRTGDMLVIDAEAGVLDIEI
DAAEWAARPNAVPLHQAENEVGFGRELFGVFRAAAAPAEQGASVFGAMVGERSAHHGEAAEAHTGKHTSTTQAS
>Mature_634_residues
MVSPHSQLLKVTQRVVERSKPTREAYLARIEQAQGRFPARGALSCANLAHGFAGLEGNDKLVIKQIREPNIGIVSSYNEM
LSAHAPYKNYPDIIKQAARENGGVAQFAGGVPAMCDGVTQGNAGMELSLFSREVIAMSTAVALTHNMFDAALCLGICDKI
VPGLLIGALQFGHLPTIFVPAGPMGSGLSNDDKAKTRQLFATGQCGRDALLEAEAAAYHSHGTCTFYGTANSNQMLMEVM
GLHLPSSAFVHPHTPLRDALTAQAARRVLDLTVERGNYTPIGHVVDEKAIVNGIVALLATGGSTNHTLHLVAIARAAGIV
IDWDDFDALSQAVPLLAKIYPNGKADVNHFHAAGGVAFLVRNLLEGGLLHEDVNTVAGKGLKHYTEEPKLIDGKLQWVPG
AEASEDTAVLRGIKEPFQPDGGLRLMQGKLGRGVIKISAVAAQHRKVKAPAIVFDSQEAVQEAFDKGELKRDFIAVVRFQ
GARANGMPELHRLTPLLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLQGPIGKVRTGDMLVIDAEAGVLDIEI
DAAEWAARPNAVPLHQAENEVGFGRELFGVFRAAAAPAEQGASVFGAMVGERSAHHGEAAEAHTGKHTSTTQAS

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI1788157, Length=599, Percent_Identity=59.9332220367279, Blast_Score=733, Evalue=0.0,
Organism=Escherichia coli, GI48994964, Length=542, Percent_Identity=29.7047970479705, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI2367371, Length=480, Percent_Identity=31.4583333333333, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI1786464, Length=502, Percent_Identity=31.4741035856574, Blast_Score=146, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322476, Length=525, Percent_Identity=28.952380952381, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004786
- InterPro:   IPR015928
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.12 [H]

Molecular weight: Translated: 67156; Mature: 67156

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00886 ILVD_EDD_1 ; PS00887 ILVD_EDD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPHSQLLKVTQRVVERSKPTREAYLARIEQAQGRFPARGALSCANLAHGFAGLEGNDK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
LVIKQIREPNIGIVSSYNEMLSAHAPYKNYPDIIKQAARENGGVAQFAGGVPAMCDGVTQ
EEEEECCCCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHCCCCC
GNAGMELSLFSREVIAMSTAVALTHNMFDAALCLGICDKIVPGLLIGALQFGHLPTIFVP
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGPMGSGLSNDDKAKTRQLFATGQCGRDALLEAEAAAYHSHGTCTFYGTANSNQMLMEVM
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
GLHLPSSAFVHPHTPLRDALTAQAARRVLDLTVERGNYTPIGHVVDEKAIVNGIVALLAT
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
GGSTNHTLHLVAIARAAGIVIDWDDFDALSQAVPLLAKIYPNGKADVNHFHAAGGVAFLV
CCCCCCEEEEEEEEHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RNLLEGGLLHEDVNTVAGKGLKHYTEEPKLIDGKLQWVPGAEASEDTAVLRGIKEPFQPD
HHHHCCCCCHHHHHHHHCCCHHHHCCCCCEECCEEEECCCCCCCCHHHHHHHHHHCCCCC
GGLRLMQGKLGRGVIKISAVAAQHRKVKAPAIVFDSQEAVQEAFDKGELKRDFIAVVRFQ
CCEEEECCCCCCCEEEEEHHHHHHHCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHEEC
GARANGMPELHRLTPLLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLQGPIGK
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEECHHHHHCCCCCC
VRTGDMLVIDAEAGVLDIEIDAAEWAARPNAVPLHQAENEVGFGRELFGVFRAAAAPAEQ
CCCCCEEEEECCCCEEEEEECHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH
GASVFGAMVGERSAHHGEAAEAHTGKHTSTTQAS
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVSPHSQLLKVTQRVVERSKPTREAYLARIEQAQGRFPARGALSCANLAHGFAGLEGNDK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
LVIKQIREPNIGIVSSYNEMLSAHAPYKNYPDIIKQAARENGGVAQFAGGVPAMCDGVTQ
EEEEECCCCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHCCCCC
GNAGMELSLFSREVIAMSTAVALTHNMFDAALCLGICDKIVPGLLIGALQFGHLPTIFVP
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGPMGSGLSNDDKAKTRQLFATGQCGRDALLEAEAAAYHSHGTCTFYGTANSNQMLMEVM
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
GLHLPSSAFVHPHTPLRDALTAQAARRVLDLTVERGNYTPIGHVVDEKAIVNGIVALLAT
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
GGSTNHTLHLVAIARAAGIVIDWDDFDALSQAVPLLAKIYPNGKADVNHFHAAGGVAFLV
CCCCCCEEEEEEEEHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RNLLEGGLLHEDVNTVAGKGLKHYTEEPKLIDGKLQWVPGAEASEDTAVLRGIKEPFQPD
HHHHCCCCCHHHHHHHHCCCHHHHCCCCCEECCEEEECCCCCCCCHHHHHHHHHHCCCCC
GGLRLMQGKLGRGVIKISAVAAQHRKVKAPAIVFDSQEAVQEAFDKGELKRDFIAVVRFQ
CCEEEECCCCCCCEEEEEHHHHHHHCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHEEC
GARANGMPELHRLTPLLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLQGPIGK
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEECHHHHHCCCCCC
VRTGDMLVIDAEAGVLDIEIDAAEWAARPNAVPLHQAENEVGFGRELFGVFRAAAAPAEQ
CCCCCEEEEECCCCEEEEEECHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH
GASVFGAMVGERSAHHGEAAEAHTGKHTSTTQAS
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]