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The map label for this gene is cbbA [H]

Identifier: 91785089

GI number: 91785089

Start: 4120629

End: 4121693

Strand: Reverse

Name: cbbA [H]

Synonym: Bxe_A0691

Alternate gene names: 91785089

Gene position: 4121693-4120629 (Counterclockwise)

Preceding gene: 91785090

Following gene: 91785088

Centisome position: 84.19

GC content: 61.97

Gene sequence:

>1065_bases
ATGCCTCTCGTATCAATGCGTCAACTGCTGGACCATGCCGCTGAAAACGGCTATGGGCTTCCGGCATTCAACGTGAACAA
CCTGGAGCAGGTGCAGGCGATCATGGCGGCCGCCGACAAGGTCAACGCACCGGTCATCATGCAGGCTTCGGCCGGCGCGC
GTAAGTACGCGGGCGAGGCGTTCCTGCGCCACCTGATCGAAGCCGCGGTCGAGTCGTATCCGCATATTCCGGTCGTGATG
CACCAGGACCACGGCCAGTCGCCGGCGGTCTGCATGGCGGCGATCCGCAGCGGTTTCACCAGCGTGATGATGGACGGTTC
GCTCGAAGCCGACGGCAAGACGGTCGCCTCGTACGAGTACAACGTCGACGTGTCGCGCAGGGTCGTGGAAGCGGCGCATT
CGATCGGTATCACGGTGGAAGCGGAACTGGGCGTGCTCGGTTCGCTGGAAACCATGAAGGGAGACAAGGAAGACGGCCAC
GGCGCGGAAGGCACGATGACGCGCGAGCAGTTGTTGACCGATCCGGAACAGGCTGCCGACTTCGTCAAGCTGACCCAGTG
CGACGCGCTGGCTATCGCGATCGGCACCTCGCACGGCGCGTACAAGTTCAGCAAGAAGCCCACGGGCGACATTCTGTCGA
TCCAGCGTATCAAGGAAATCCACCAGCGCATTCCGAACACGCACCTGGTGATGCACGGTTCGTCGTCGGTGCCGCAGGAA
CTGCTCGCTGAAATCCGCGAATTCGGCGGCGACATGAAGGAAACCTACGGCGTGCCGGTCGAGGAAATCCAGGAAGGCAT
CAAGAACGGCGTGCGCAAGGTCAATATCGACACCGACCTGCGTCTGGCGATCACCGGCGCGATCCGCCGCTACATGGCGA
CCAACCCGGGCAAGTTCGATCCGCGCGATTACCTGAAGCCGGCGCGCGAAGCGGCGATGAAGATCTGTATCGAGCGCTAC
ACGCAATTCGGTTGCGAAGGCCAGGCGGGCAAGATCAAGCCGGTCACGCTTGATAAAATCGCGGAGAAGTACAAGTCGGG
CGAGCTCGCGCAAGTCGTCCGCTAA

Upstream 100 bases:

>100_bases
GCTTCAGGGAAGGTGTGACGGGTATGCAGCATGCTTCGCGATAAAATCGCCCAAAAGATGCCGACGGCACAGGAATTCGT
TTCAATCTAAGGAGTTAAGC

Downstream 100 bases:

>100_bases
GCTATCAACATGCACTGCGCCTGGCCGTTTGGCCAGGTTGTCGTTAGATCGCCGTTCCCGCATCATCCGGGGAACGGCGT
TTCCCTTTTGTTCCGGTCAC

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MPLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMAAADKVNAPVIMQASAGARKYAGEAFLRHLIEAAVESYPHIPVVM
HQDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKTVASYEYNVDVSRRVVEAAHSIGITVEAELGVLGSLETMKGDKEDGH
GAEGTMTREQLLTDPEQAADFVKLTQCDALAIAIGTSHGAYKFSKKPTGDILSIQRIKEIHQRIPNTHLVMHGSSSVPQE
LLAEIREFGGDMKETYGVPVEEIQEGIKNGVRKVNIDTDLRLAITGAIRRYMATNPGKFDPRDYLKPAREAAMKICIERY
TQFGCEGQAGKIKPVTLDKIAEKYKSGELAQVVR

Sequences:

>Translated_354_residues
MPLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMAAADKVNAPVIMQASAGARKYAGEAFLRHLIEAAVESYPHIPVVM
HQDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKTVASYEYNVDVSRRVVEAAHSIGITVEAELGVLGSLETMKGDKEDGH
GAEGTMTREQLLTDPEQAADFVKLTQCDALAIAIGTSHGAYKFSKKPTGDILSIQRIKEIHQRIPNTHLVMHGSSSVPQE
LLAEIREFGGDMKETYGVPVEEIQEGIKNGVRKVNIDTDLRLAITGAIRRYMATNPGKFDPRDYLKPAREAAMKICIERY
TQFGCEGQAGKIKPVTLDKIAEKYKSGELAQVVR
>Mature_353_residues
PLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMAAADKVNAPVIMQASAGARKYAGEAFLRHLIEAAVESYPHIPVVMH
QDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKTVASYEYNVDVSRRVVEAAHSIGITVEAELGVLGSLETMKGDKEDGHG
AEGTMTREQLLTDPEQAADFVKLTQCDALAIAIGTSHGAYKFSKKPTGDILSIQRIKEIHQRIPNTHLVMHGSSSVPQEL
LAEIREFGGDMKETYGVPVEEIQEGIKNGVRKVNIDTDLRLAITGAIRRYMATNPGKFDPRDYLKPAREAAMKICIERYT
QFGCEGQAGKIKPVTLDKIAEKYKSGELAQVVR

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=33.434650455927, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789526, Length=316, Percent_Identity=34.1772151898734, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788072, Length=329, Percent_Identity=28.5714285714286, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789293, Length=368, Percent_Identity=25.2717391304348, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38536; Mature: 38404

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMAAADKVNAPVIMQASAGARKYAGEA
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
FLRHLIEAAVESYPHIPVVMHQDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKTVASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCEEEEEEE
NVDVSRRVVEAAHSIGITVEAELGVLGSLETMKGDKEDGHGAEGTMTREQLLTDPEQAAD
CCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHH
FVKLTQCDALAIAIGTSHGAYKFSKKPTGDILSIQRIKEIHQRIPNTHLVMHGSSSVPQE
HHHHHHCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
LLAEIREFGGDMKETYGVPVEEIQEGIKNGVRKVNIDTDLRLAITGAIRRYMATNPGKFD
HHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCCC
PRDYLKPAREAAMKICIERYTQFGCEGQAGKIKPVTLDKIAEKYKSGELAQVVR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
PLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMAAADKVNAPVIMQASAGARKYAGEA
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
FLRHLIEAAVESYPHIPVVMHQDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKTVASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCEEEEEEE
NVDVSRRVVEAAHSIGITVEAELGVLGSLETMKGDKEDGHGAEGTMTREQLLTDPEQAAD
CCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHH
FVKLTQCDALAIAIGTSHGAYKFSKKPTGDILSIQRIKEIHQRIPNTHLVMHGSSSVPQE
HHHHHHCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
LLAEIREFGGDMKETYGVPVEEIQEGIKNGVRKVNIDTDLRLAITGAIRRYMATNPGKFD
HHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCCC
PRDYLKPAREAAMKICIERYTQFGCEGQAGKIKPVTLDKIAEKYKSGELAQVVR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550527 [H]