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The map label for this gene is purE [H]

Identifier: 91785087

GI number: 91785087

Start: 4118935

End: 4119453

Strand: Reverse

Name: purE [H]

Synonym: Bxe_A0693

Alternate gene names: 91785087

Gene position: 4119453-4118935 (Counterclockwise)

Preceding gene: 91785088

Following gene: 91785086

Centisome position: 84.14

GC content: 65.32

Gene sequence:

>519_bases
ATGAGTGAAGCTCAAACCGCCCATACGCATGGCGCGCCGGTTGTCGGCGTGCTGATGGGCTCCAGTTCCGACTGGGAAGT
CATGAAGAACGCCGTGGCCATTCTGCAGGAATTCGGCGTGCCCTACGAAGCGAAGGTCGTGTCCGCGCACCGCATGCCCG
ACGAAATGTTCGCCTATGCTGAAAGCGCGCGTGAACGCGGCATTCGCGCGATCATCGCCGGCGCGGGCGGCGCGGCGCAT
CTGCCGGGCATGCTGGCGGCCAAGACCACGGTGCCGGTGCTCGGCGTGCCGGTGGCGAGCAAGTACCTGAAGGGCGTCGA
TTCGCTGCATTCGATCGTGCAGATGCCCAAGGGCGTGCCGGTCGCCACGTTTGCGATTGGCGAAGCCGGCGCGGCGAACG
CGGCACTGTTCGCCGTGTCGCTGCTGAGCGGCACGAGCAATGAATACGCGGAGAAGCTGGCTGCGTTCCGCGTGCGCCAG
AACGAAGCGGCTCACGCTATGGTGTTGCCGGCGCTATAA

Upstream 100 bases:

>100_bases
AAAGACCGCCCCAGGTTTTCCGCTTCGCCGTTGGTCCCCGCGGGGGCTGGCGCGAATCGACCGGTTCCGGGGCGCTCTCG
AGAAACAAGGAAGCCGTAAC

Downstream 100 bases:

>100_bases
GCGCACAGACTGATTGCTTCAAGACGTCCCCCTGTCCGACCCCCGGCCGGGTGCCTGCCATCGCATTGCATGCACACCGG
CCGCGACCGACCACTAAGAT

Product: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate(AIR) carboxylase

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSEAQTAHTHGAPVVGVLMGSSSDWEVMKNAVAILQEFGVPYEAKVVSAHRMPDEMFAYAESARERGIRAIIAGAGGAAH
LPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSLLSGTSNEYAEKLAAFRVRQ
NEAAHAMVLPAL

Sequences:

>Translated_172_residues
MSEAQTAHTHGAPVVGVLMGSSSDWEVMKNAVAILQEFGVPYEAKVVSAHRMPDEMFAYAESARERGIRAIIAGAGGAAH
LPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSLLSGTSNEYAEKLAAFRVRQ
NEAAHAMVLPAL
>Mature_171_residues
SEAQTAHTHGAPVVGVLMGSSSDWEVMKNAVAILQEFGVPYEAKVVSAHRMPDEMFAYAESARERGIRAIIAGAGGAAHL
PGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSLLSGTSNEYAEKLAAFRVRQN
EAAHAMVLPAL

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=148, Percent_Identity=58.7837837837838, Blast_Score=148, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324702, Length=150, Percent_Identity=60, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17795; Mature: 17664

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAQTAHTHGAPVVGVLMGSSSDWEVMKNAVAILQEFGVPYEAKVVSAHRMPDEMFAYA
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHH
ESARERGIRAIIAGAGGAAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVP
HHHHHCCCEEEEECCCCHHHCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCC
VATFAIGEAGAANAALFAVSLLSGTSNEYAEKLAAFRVRQNEAAHAMVLPAL
EEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
>Mature Secondary Structure 
SEAQTAHTHGAPVVGVLMGSSSDWEVMKNAVAILQEFGVPYEAKVVSAHRMPDEMFAYA
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHH
ESARERGIRAIIAGAGGAAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVP
HHHHHCCCEEEEECCCCHHHCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCC
VATFAIGEAGAANAALFAVSLLSGTSNEYAEKLAAFRVRQNEAAHAMVLPAL
EEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]