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The map label for this gene is era [H]

Identifier: 91784706

GI number: 91784706

Start: 3693434

End: 3694333

Strand: Reverse

Name: era [H]

Synonym: Bxe_A1086

Alternate gene names: 91784706

Gene position: 3694333-3693434 (Counterclockwise)

Preceding gene: 91784707

Following gene: 91784705

Centisome position: 75.46

GC content: 61.78

Gene sequence:

>900_bases
ATGAACGCTCCCACTCCCACTGGTTTTCGCTGCGGCATGGTCGCGATCGTCGGCCGCCCCAACGTCGGCAAATCCACGCT
GATGAACGCGCTGGTCGGCCAGAAAGTCAGTATCACGTCGCGCAAGGCGCAGACCACGCGCCATCGCATCACGGGCATTC
ATACGCTCGAAGACGCGCAATACATTTTCGTCGACACGCCCGGCTTTCAGACGAAGCACAGCGGCGCGCTGAACCGTTCG
CTCAATCGCGCGGTCACGTCCACGCTGACTTCCGTGGATGCGATCCTGTTCGTGATCGAAGCCGGCCGTTTCGGCCCGGA
CGACCAGAAAGTGCTCGACCTGATTCCGCCGTCGGTGCCCACGCTGCTGATCGCGAACAAGCTCGATCGCGTGTCCGATA
AGGACTCGCTGTTCCCGTTCATGCAGCAGGTCAGCGCGCTGCACAAGTTCGCCGAGATCGTGCCGCTGTCGGCGAAACAT
CCCGACGACATCAAGCGCCTGATGGCGACCGTCAAGCCGTTCCTGCCGGAAGGCGCGCCGATCTACGGCGAAGACGACCT
GACCGATCGCAGCGAGCGGTTCCTGGCTGCGGAAATCCTGCGCGAGAAAGTGTTCCGCTGGACCGGCGACGAACTGCCGT
ACACGAGCACCGTGCTGATCGACAAGTTCGAAACCGAAGGGCGCCTGCGCCGTATCTTCGCGACCATCATGGTGGACCGC
GACACGCACAAGGCGATGATCATCGGCCAGAAGGGTGCGAAGCTGAAGCAGATCAGCACCGAAGCGCGCCTCGACATGGA
AAAGCTGTTCGACGGTCCGGTGTATCTGGAAACCTTCATCAAGGTGAAGAGCGGCTGGGCCGACAACGAAGCCGGGCTCC
GTGCGTATGGGTACGAATGA

Upstream 100 bases:

>100_bases
CGTAGCCGACGCGGTGCAAACGCGCGTCGCCGACGCGGGCCATTGATTGCCATCGGCGCGCCCATTGCGCGTGTCGATCT
GAACTTGCCGTAGCCCGAAT

Downstream 100 bases:

>100_bases
CGCGTGGATGACGCTGAATTCCGACGCCGACCCGGACGACCCGGAGCCGGCCGCGCCGGCACGCGATCTGTCCAAACCCG
CGTCCAAACCTGCTCGTAGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNAPTPTGFRCGMVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGIHTLEDAQYIFVDTPGFQTKHSGALNRS
LNRAVTSTLTSVDAILFVIEAGRFGPDDQKVLDLIPPSVPTLLIANKLDRVSDKDSLFPFMQQVSALHKFAEIVPLSAKH
PDDIKRLMATVKPFLPEGAPIYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATIMVDR
DTHKAMIIGQKGAKLKQISTEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE

Sequences:

>Translated_299_residues
MNAPTPTGFRCGMVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGIHTLEDAQYIFVDTPGFQTKHSGALNRS
LNRAVTSTLTSVDAILFVIEAGRFGPDDQKVLDLIPPSVPTLLIANKLDRVSDKDSLFPFMQQVSALHKFAEIVPLSAKH
PDDIKRLMATVKPFLPEGAPIYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATIMVDR
DTHKAMIIGQKGAKLKQISTEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE
>Mature_299_residues
MNAPTPTGFRCGMVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGIHTLEDAQYIFVDTPGFQTKHSGALNRS
LNRAVTSTLTSVDAILFVIEAGRFGPDDQKVLDLIPPSVPTLLIANKLDRVSDKDSLFPFMQQVSALHKFAEIVPLSAKH
PDDIKRLMATVKPFLPEGAPIYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATIMVDR
DTHKAMIIGQKGAKLKQISTEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=319, Percent_Identity=25.705329153605, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=290, Percent_Identity=50, Blast_Score=294, Evalue=4e-81,
Organism=Escherichia coli, GI87082120, Length=171, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646434, Length=308, Percent_Identity=25.974025974026, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33310; Mature: 33310

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPTPTGFRCGMVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGIHTLEDAQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHHCEEEECCCC
YIFVDTPGFQTKHSGALNRSLNRAVTSTLTSVDAILFVIEAGRFGPDDQKVLDLIPPSVP
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHCCCCCH
TLLIANKLDRVSDKDSLFPFMQQVSALHKFAEIVPLSAKHPDDIKRLMATVKPFLPEGAP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
IYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATIMVDR
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
DTHKAMIIGQKGAKLKQISTEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE
CCCCEEEEECCCCHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCC
>Mature Secondary Structure
MNAPTPTGFRCGMVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGIHTLEDAQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHHCEEEECCCC
YIFVDTPGFQTKHSGALNRSLNRAVTSTLTSVDAILFVIEAGRFGPDDQKVLDLIPPSVP
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHCCCCCH
TLLIANKLDRVSDKDSLFPFMQQVSALHKFAEIVPLSAKHPDDIKRLMATVKPFLPEGAP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
IYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATIMVDR
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
DTHKAMIIGQKGAKLKQISTEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE
CCCCEEEEECCCCHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]