| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is fadH [H]
Identifier: 91784406
GI number: 91784406
Start: 3376619
End: 3377539
Strand: Reverse
Name: fadH [H]
Synonym: Bxe_A1394
Alternate gene names: 91784406
Gene position: 3377539-3376619 (Counterclockwise)
Preceding gene: 91784408
Following gene: 91784405
Centisome position: 68.99
GC content: 63.52
Gene sequence:
>921_bases ATGCCCGCAGCTTCGTCGAGCACCTCGCCGCCGTCAAACGGCTATCGTTCGGTTTTCCGCGAAGGCCTCTTCGCCGGCAA AGTCATTATCGTCACCGGCGCGGGTAGCGGTTTAGGCCGATGCACCGCGCACGAACTCGCATCCTTAGGCGCAACCCTGG CGCTGGTCGGCCGAAGCGAGGACAAACTGAAAGCGGTGCAAGCCGAACTGGCCGAAGATCATCAACGCACCTCCGCCGGA CACAAGACCTATTCCTGCGACATCCGCAACGAGCAACAGGTCCGCGAAACGATCGCTTCGATCATTGCGGATCTGGGCCG CGTAGACGGCCTCTTCAATTGCGCGGGCGGCCAGTTCCCCGCGAAGCTCGAAAAGATTTCCCTGAATGGCTGGGACGCGG TAGTGCGCAACAATCTGCACGGCACGTTTCTGATGTCCCGCGAATGCTATACGCAATGGATGGAACATCACGGCGGAACG ATCGTGAACATGCTGGCGGATATCTGGGGCGGCATGCCCGGCATGGGTCACTCGGGCGCGGCGCGGGCGGGCGTGTGGAA CTTCACGGAAACCGCCGCATGCGAATGGGGCCACGCGGGGGTGAGAGTCAACGCGGTCGCGCCGGGCTGGATAGCGTCCG CGGGTATGGACAGCTACAACGAAGACTACCAGGCGCTGTTGCGCACGCTCAGGCATAAGGTCCCGCTGCAGCGCTTCGGC ACCGAATCCGAACTGGCCGGCGCGGCGGTGTTTCTGTTGTCGGAGGCGTCGGCGTTCATCAACGGCACGGTGATCCGCGT CGACGGCGGCGTGCCGAACGCGCGCCACTCGTGGCCGCTTCCGCCGGCGGAGCGTACGATCGAATATAACGGCTTCCCGC GTTATCAACCGCCGACGGGCTTGCAGGAGCAGACACCATGA
Upstream 100 bases:
>100_bases ATCAGTGTGAAATAAAGTTACGGTCATGCACAACACAGGAATAAAACATGAGCTAAACTCAACAAACACCGAAAGCGCAG CACATGAAGGAGACACCCGC
Downstream 100 bases:
>100_bases ACCTCGACGGCCAGACCTACGAATCGCTGACGGCAAACTTCGCGTGGCAGATCCCGGCGCGCTACAACATCGGCGTGGAC GTGTGCGATAAATGGGCCGA
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 306; Mature: 305
Protein sequence:
>306_residues MPAASSSTSPPSNGYRSVFREGLFAGKVIIVTGAGSGLGRCTAHELASLGATLALVGRSEDKLKAVQAELAEDHQRTSAG HKTYSCDIRNEQQVRETIASIIADLGRVDGLFNCAGGQFPAKLEKISLNGWDAVVRNNLHGTFLMSRECYTQWMEHHGGT IVNMLADIWGGMPGMGHSGAARAGVWNFTETAACEWGHAGVRVNAVAPGWIASAGMDSYNEDYQALLRTLRHKVPLQRFG TESELAGAAVFLLSEASAFINGTVIRVDGGVPNARHSWPLPPAERTIEYNGFPRYQPPTGLQEQTP
Sequences:
>Translated_306_residues MPAASSSTSPPSNGYRSVFREGLFAGKVIIVTGAGSGLGRCTAHELASLGATLALVGRSEDKLKAVQAELAEDHQRTSAG HKTYSCDIRNEQQVRETIASIIADLGRVDGLFNCAGGQFPAKLEKISLNGWDAVVRNNLHGTFLMSRECYTQWMEHHGGT IVNMLADIWGGMPGMGHSGAARAGVWNFTETAACEWGHAGVRVNAVAPGWIASAGMDSYNEDYQALLRTLRHKVPLQRFG TESELAGAAVFLLSEASAFINGTVIRVDGGVPNARHSWPLPPAERTIEYNGFPRYQPPTGLQEQTP >Mature_305_residues PAASSSTSPPSNGYRSVFREGLFAGKVIIVTGAGSGLGRCTAHELASLGATLALVGRSEDKLKAVQAELAEDHQRTSAGH KTYSCDIRNEQQVRETIASIIADLGRVDGLFNCAGGQFPAKLEKISLNGWDAVVRNNLHGTFLMSRECYTQWMEHHGGTI VNMLADIWGGMPGMGHSGAARAGVWNFTETAACEWGHAGVRVNAVAPGWIASAGMDSYNEDYQALLRTLRHKVPLQRFGT ESELAGAAVFLLSEASAFINGTVIRVDGGVPNARHSWPLPPAERTIEYNGFPRYQPPTGLQEQTP
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=39.1791044776119, Blast_Score=201, Evalue=6e-52, Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=32.2222222222222, Blast_Score=128, Evalue=6e-30, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=32.4110671936759, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=32.2709163346614, Blast_Score=112, Evalue=5e-25, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=30.4, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=31.8407960199005, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=25.9541984732824, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI5031737, Length=272, Percent_Identity=26.1029411764706, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=27.8761061946903, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503817, Length=174, Percent_Identity=29.3103448275862, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=26.0700389105058, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=32.2033898305085, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=30, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=31.2, Blast_Score=101, Evalue=8e-23, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=32, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=27.6264591439689, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=28.968253968254, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=29.0836653386454, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=25.4826254826255, Blast_Score=79, Evalue=5e-16, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=29.4820717131474, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787526, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1789378, Length=276, Percent_Identity=24.6376811594203, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=26.1363636363636, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=30.188679245283, Blast_Score=117, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=29.0566037735849, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=29.7619047619048, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=29.1338582677165, Blast_Score=107, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=30.6451612903226, Blast_Score=104, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17561272, Length=287, Percent_Identity=31.0104529616725, Blast_Score=101, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=31.0606060606061, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=27.8195488721804, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=31.2252964426877, Blast_Score=92, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=25.6704980842912, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.8195488721804, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=25.7575757575758, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=24.2307692307692, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=24.6268656716418, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=26.3940520446097, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=260, Percent_Identity=27.6923076923077, Blast_Score=78, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=26.9961977186312, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=26.8939393939394, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=25.5905511811024, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=25.6704980842912, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.2357414448669, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561402, Length=267, Percent_Identity=25.4681647940075, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=26.7175572519084, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=27.3408239700375, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71982365, Length=137, Percent_Identity=29.1970802919708, Blast_Score=66, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=29.8449612403101, Blast_Score=127, Evalue=2e-30, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=30.5699481865285, Blast_Score=71, Evalue=3e-13, Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=35.2941176470588, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=34.7169811320755, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=32.156862745098, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=35.361216730038, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=33.969465648855, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30.8, Blast_Score=95, Evalue=7e-20, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=26.171875, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=32.5581395348837, Blast_Score=85, Evalue=7e-17, Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=27.9187817258883, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI17737361, Length=265, Percent_Identity=27.1698113207547, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21356301, Length=187, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 32834; Mature: 32703
Theoretical pI: Translated: 6.85; Mature: 6.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPAASSSTSPPSNGYRSVFREGLFAGKVIIVTGAGSGLGRCTAHELASLGATLALVGRSE CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCH DKLKAVQAELAEDHQRTSAGHKTYSCDIRNEQQVRETIASIIADLGRVDGLFNCAGGQFP HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCC AKLEKISLNGWDAVVRNNLHGTFLMSRECYTQWMEHHGGTIVNMLADIWGGMPGMGHSGA CHHEEEECCCHHHHHHCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC ARAGVWNFTETAACEWGHAGVRVNAVAPGWIASAGMDSYNEDYQALLRTLRHKVPLQRFG CCCCCCCCCHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHCC TESELAGAAVFLLSEASAFINGTVIRVDGGVPNARHSWPLPPAERTIEYNGFPRYQPPTG CHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCC LQEQTP CCCCCC >Mature Secondary Structure PAASSSTSPPSNGYRSVFREGLFAGKVIIVTGAGSGLGRCTAHELASLGATLALVGRSE CCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCH DKLKAVQAELAEDHQRTSAGHKTYSCDIRNEQQVRETIASIIADLGRVDGLFNCAGGQFP HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCC AKLEKISLNGWDAVVRNNLHGTFLMSRECYTQWMEHHGGTIVNMLADIWGGMPGMGHSGA CHHEEEECCCHHHHHHCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC ARAGVWNFTETAACEWGHAGVRVNAVAPGWIASAGMDSYNEDYQALLRTLRHKVPLQRFG CCCCCCCCCHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHCC TESELAGAAVFLLSEASAFINGTVIRVDGGVPNARHSWPLPPAERTIEYNGFPRYQPPTG CHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCC LQEQTP CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]