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The map label for this gene is 91784326

Identifier: 91784326

GI number: 91784326

Start: 3287484

End: 3289466

Strand: Reverse

Name: 91784326

Synonym: Bxe_A1474

Alternate gene names: NA

Gene position: 3289466-3287484 (Counterclockwise)

Preceding gene: 91784327

Following gene: 91784325

Centisome position: 67.19

GC content: 64.6

Gene sequence:

>1983_bases
ATGGACGCGGTCCGTACCGCAGTAATGAACAACCGTTTCACGGCAATCGTCGAGGAAGCTTCGGCGATCATGTACCGGAC
GGCGCACACGACCTTCGTCAAACTCGTGCAGGACTACCAGTGCGCGATCGCGACGGCGGCCGGCGAGATCTTCGCGTATC
CGGGTCAGAGCGGGGTGAATTCTTTCATCGGCCTGCCGCTGCAGGCAACCGTCGAACGGCTGCTGGAGATCGGGATCGAG
GAGGGCGACTGTTTCCTCACCAACGACCCGTTCTCCACTGACGGACTCGTCACCCACATGATGGATGTGACGATGCTCCG
CCCGATTTTTTTTGGTGGGCGCCTAATGGCGTTTGCGTGGGGCTTCGTTCACGCATCCGACATTGGCGGCGCCGTGCCGG
GCAGTATTTCGCCGGCCTTCACCGAAGTGTTTCAGGAAGGGCTGCGCATCCGCCCCGTGAAGCTCTACAAGGCGGGCGTG
CTCAATGAAGACGTGCGCACTCTCTTTCTCGACAACAGCCGGATTCCGGATGATCTATGGGGTGACCTGAAAGCGATGCT
GTCCGCATTACAAAGTATGGACCGCAGATTCAGGCAGTTGTGCGATGCCTACGGCGCGGACGTCGTCGAAGAGGGCATGC
AGGACGTGCTGGACTTCGCGGAGGCCAAGGCGCGCGGCGTGATCGCGTCGATACCGGACGGCGTATACGAGTTCGGCGAC
TATCTGGAGGGACTCGAACCCGGCCAGCACACCTATATCCGTACGTCGATGAAGGTGAAGGGCGATAGCCTCGGCTTCGA
TTTCACCGGCACCGATCCGCAGATTCCGGCCGCGTACAACTACGTGAGCGGCGCGCGCACGCATCCTTACACGGTGCAGG
CGTTTCTTTATTACCTGTTGACGGTGGAACCCGACGCGCCGCGCAATGCGGGCCTGCTGCGGCCCATCGCCATGCACGCG
CCGCGCGGCACCGTCATCAATGCGGAGTTTCCGGCGGCGGGCGGCTCGCGCGTCGCGGCCAGCACGCGCGTCTACGACAC
GATGCTTGGCTGCCTGCAACAGGCGGTCGCCGGCGGTCTCTCGGCGGCGGGGCCCGGCATGTCGGCGGTGATCGTGCTCA
GTGCGCGCGATCCGCGTACCGGCAAGCGGCAGGTGAGCGTGATCAACCCGCTTTGCGGAGGCGGGGGTGGACGCTCGGTA
TGCGATGGCGTCGATGCAATCGACTCGCGCTCCGGTTATCTACGCAGCGTGCCGACCGAAATCATCGAAGTGGAAACGAT
GCTGTTCGTGCGCGCCAATCGTCTGCTGAAAGACAGCTATTCGGCGGGCCGCTATCGCAGCGGCGCGGCGCTCGTGATGG
AAATGGAAAACACCGACGCCGAAGCAACGATGACGATTCGCGGCATGAACCGCTTTGCGTTCCGGCCGTGGGGCGTTGCC
GGCGGCCATCCGGGACGGCTCGCCGAGGTCACGATCAATCCAGGCACGCCGGGCGAACAGGTGCTTGAACGCGTGACCGT
ACTCAAACTCAAGCGTGACGACGTGATCCGGCTCGTGACACCGGCGGGCGGCGGATTTGGCGACCCGCTCGAGCGCGACC
TCGCGGCGATCGAAAGCGATCTGCGGCGCGAGATGCTGTCGGCCGAAGCGGCGACGCGCGACTATGGCGTGGCCTTCGCG
CTGGACGGTTCGATCGATCGCAGCGGCACCGAGACGCTGCGCGCCGCGCGCCGTTCTTCGACGTCGCCGCCTGTCTTCAC
GATGGGCCCGGAGCGCGACGCGTACGACGGCATCTGGCCTGACCACGTACGCGCGCAATTCGCCACGTCCGCATTGAATC
GTCCGCAGGCGCATCGGCAACTGCTGGTGGATGCCGTGCGCCAGCGCCTGACCACTGCGGGCGGGACCGTGACGCCCGGG
ACGCTCGAACGCGTGCTCGACGAGGAGGCCGTGAAGCTGTCGGGCCCGAACGTATTGCATTGA

Upstream 100 bases:

>100_bases
GCGATCATCGAACAGCACGACACGACGATTCTGGTGCCACCACACTACCGGGCGACCGTCGATGCCCACGGCAACATCCT
GCTTGAGAAGGAGTCTTGAG

Downstream 100 bases:

>100_bases
ACCAAGGGATGGGCTGCGTGCGACGCGAGAGTTGCATCAGGTCCGCGAGACAACCTGTTTTGGGTGAGAGAGAAATGCTG
AAGAAAACCTGTCGTACCGG

Product: 5-oxoprolinase (ATP-hydrolyzing)

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MDAVRTAVMNNRFTAIVEEASAIMYRTAHTTFVKLVQDYQCAIATAAGEIFAYPGQSGVNSFIGLPLQATVERLLEIGIE
EGDCFLTNDPFSTDGLVTHMMDVTMLRPIFFGGRLMAFAWGFVHASDIGGAVPGSISPAFTEVFQEGLRIRPVKLYKAGV
LNEDVRTLFLDNSRIPDDLWGDLKAMLSALQSMDRRFRQLCDAYGADVVEEGMQDVLDFAEAKARGVIASIPDGVYEFGD
YLEGLEPGQHTYIRTSMKVKGDSLGFDFTGTDPQIPAAYNYVSGARTHPYTVQAFLYYLLTVEPDAPRNAGLLRPIAMHA
PRGTVINAEFPAAGGSRVAASTRVYDTMLGCLQQAVAGGLSAAGPGMSAVIVLSARDPRTGKRQVSVINPLCGGGGGRSV
CDGVDAIDSRSGYLRSVPTEIIEVETMLFVRANRLLKDSYSAGRYRSGAALVMEMENTDAEATMTIRGMNRFAFRPWGVA
GGHPGRLAEVTINPGTPGEQVLERVTVLKLKRDDVIRLVTPAGGGFGDPLERDLAAIESDLRREMLSAEAATRDYGVAFA
LDGSIDRSGTETLRAARRSSTSPPVFTMGPERDAYDGIWPDHVRAQFATSALNRPQAHRQLLVDAVRQRLTTAGGTVTPG
TLERVLDEEAVKLSGPNVLH

Sequences:

>Translated_660_residues
MDAVRTAVMNNRFTAIVEEASAIMYRTAHTTFVKLVQDYQCAIATAAGEIFAYPGQSGVNSFIGLPLQATVERLLEIGIE
EGDCFLTNDPFSTDGLVTHMMDVTMLRPIFFGGRLMAFAWGFVHASDIGGAVPGSISPAFTEVFQEGLRIRPVKLYKAGV
LNEDVRTLFLDNSRIPDDLWGDLKAMLSALQSMDRRFRQLCDAYGADVVEEGMQDVLDFAEAKARGVIASIPDGVYEFGD
YLEGLEPGQHTYIRTSMKVKGDSLGFDFTGTDPQIPAAYNYVSGARTHPYTVQAFLYYLLTVEPDAPRNAGLLRPIAMHA
PRGTVINAEFPAAGGSRVAASTRVYDTMLGCLQQAVAGGLSAAGPGMSAVIVLSARDPRTGKRQVSVINPLCGGGGGRSV
CDGVDAIDSRSGYLRSVPTEIIEVETMLFVRANRLLKDSYSAGRYRSGAALVMEMENTDAEATMTIRGMNRFAFRPWGVA
GGHPGRLAEVTINPGTPGEQVLERVTVLKLKRDDVIRLVTPAGGGFGDPLERDLAAIESDLRREMLSAEAATRDYGVAFA
LDGSIDRSGTETLRAARRSSTSPPVFTMGPERDAYDGIWPDHVRAQFATSALNRPQAHRQLLVDAVRQRLTTAGGTVTPG
TLERVLDEEAVKLSGPNVLH
>Mature_660_residues
MDAVRTAVMNNRFTAIVEEASAIMYRTAHTTFVKLVQDYQCAIATAAGEIFAYPGQSGVNSFIGLPLQATVERLLEIGIE
EGDCFLTNDPFSTDGLVTHMMDVTMLRPIFFGGRLMAFAWGFVHASDIGGAVPGSISPAFTEVFQEGLRIRPVKLYKAGV
LNEDVRTLFLDNSRIPDDLWGDLKAMLSALQSMDRRFRQLCDAYGADVVEEGMQDVLDFAEAKARGVIASIPDGVYEFGD
YLEGLEPGQHTYIRTSMKVKGDSLGFDFTGTDPQIPAAYNYVSGARTHPYTVQAFLYYLLTVEPDAPRNAGLLRPIAMHA
PRGTVINAEFPAAGGSRVAASTRVYDTMLGCLQQAVAGGLSAAGPGMSAVIVLSARDPRTGKRQVSVINPLCGGGGGRSV
CDGVDAIDSRSGYLRSVPTEIIEVETMLFVRANRLLKDSYSAGRYRSGAALVMEMENTDAEATMTIRGMNRFAFRPWGVA
GGHPGRLAEVTINPGTPGEQVLERVTVLKLKRDDVIRLVTPAGGGFGDPLERDLAAIESDLRREMLSAEAATRDYGVAFA
LDGSIDRSGTETLRAARRSSTSPPVFTMGPERDAYDGIWPDHVRAQFATSALNRPQAHRQLLVDAVRQRLTTAGGTVTPG
TLERVLDEEAVKLSGPNVLH

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=558, Percent_Identity=28.8530465949821, Blast_Score=149, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI133901900, Length=555, Percent_Identity=27.2072072072072, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI133901902, Length=517, Percent_Identity=26.1121856866538, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322634, Length=555, Percent_Identity=24.8648648648649, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550492, Length=566, Percent_Identity=25.0883392226148, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71278; Mature: 71278

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVRTAVMNNRFTAIVEEASAIMYRTAHTTFVKLVQDYQCAIATAAGEIFAYPGQSGVN
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCH
SFIGLPLQATVERLLEIGIEEGDCFLTNDPFSTDGLVTHMMDVTMLRPIFFGGRLMAFAW
HHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
GFVHASDIGGAVPGSISPAFTEVFQEGLRIRPVKLYKAGVLNEDVRTLFLDNSRIPDDLW
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHCCCCCCCCCEEEECCCCCCHHHH
GDLKAMLSALQSMDRRFRQLCDAYGADVVEEGMQDVLDFAEAKARGVIASIPDGVYEFGD
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHH
YLEGLEPGQHTYIRTSMKVKGDSLGFDFTGTDPQIPAAYNYVSGARTHPYTVQAFLYYLL
HHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHH
TVEPDAPRNAGLLRPIAMHAPRGTVINAEFPAAGGSRVAASTRVYDTMLGCLQQAVAGGL
EECCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
SAAGPGMSAVIVLSARDPRTGKRQVSVINPLCGGGGGRSVCDGVDAIDSRSGYLRSVPTE
CCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCHHHCCHHHHCCCCCCHHHCCHH
IIEVETMLFVRANRLLKDSYSAGRYRSGAALVMEMENTDAEATMTIRGMNRFAFRPWGVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCHHCCCCCCCC
GGHPGRLAEVTINPGTPGEQVLERVTVLKLKRDDVIRLVTPAGGGFGDPLERDLAAIESD
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
LRREMLSAEAATRDYGVAFALDGSIDRSGTETLRAARRSSTSPPVFTMGPERDAYDGIWP
HHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
DHVRAQFATSALNRPQAHRQLLVDAVRQRLTTAGGTVTPGTLERVLDEEAVKLSGPNVLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MDAVRTAVMNNRFTAIVEEASAIMYRTAHTTFVKLVQDYQCAIATAAGEIFAYPGQSGVN
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCH
SFIGLPLQATVERLLEIGIEEGDCFLTNDPFSTDGLVTHMMDVTMLRPIFFGGRLMAFAW
HHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
GFVHASDIGGAVPGSISPAFTEVFQEGLRIRPVKLYKAGVLNEDVRTLFLDNSRIPDDLW
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHCCCCCCCCCEEEECCCCCCHHHH
GDLKAMLSALQSMDRRFRQLCDAYGADVVEEGMQDVLDFAEAKARGVIASIPDGVYEFGD
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHH
YLEGLEPGQHTYIRTSMKVKGDSLGFDFTGTDPQIPAAYNYVSGARTHPYTVQAFLYYLL
HHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHH
TVEPDAPRNAGLLRPIAMHAPRGTVINAEFPAAGGSRVAASTRVYDTMLGCLQQAVAGGL
EECCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
SAAGPGMSAVIVLSARDPRTGKRQVSVINPLCGGGGGRSVCDGVDAIDSRSGYLRSVPTE
CCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCHHHCCHHHHCCCCCCHHHCCHH
IIEVETMLFVRANRLLKDSYSAGRYRSGAALVMEMENTDAEATMTIRGMNRFAFRPWGVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCHHCCCCCCCC
GGHPGRLAEVTINPGTPGEQVLERVTVLKLKRDDVIRLVTPAGGGFGDPLERDLAAIESD
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
LRREMLSAEAATRDYGVAFALDGSIDRSGTETLRAARRSSTSPPVFTMGPERDAYDGIWP
HHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
DHVRAQFATSALNRPQAHRQLLVDAVRQRLTTAGGTVTPGTLERVLDEEAVKLSGPNVLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]