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The map label for this gene is ndk [H]

Identifier: 91784210

GI number: 91784210

Start: 3155840

End: 3156265

Strand: Reverse

Name: ndk [H]

Synonym: Bxe_A1591

Alternate gene names: 91784210

Gene position: 3156265-3155840 (Counterclockwise)

Preceding gene: 91784212

Following gene: 91784209

Centisome position: 64.47

GC content: 59.39

Gene sequence:

>426_bases
ATGGCGATCGAACGCACCCTGTCCATTATCAAGCCGGACGCAGTGGCCAAGAACGTGATCGGCCAGATCTACACCCGTTT
CGAGAACGCTGGTCTGAAGATCGTGGCATCGCGCATGGTTCACCTGTCGCGCGCCGACGCGGAGAAGTTCTACGCTGTGC
ACGCAGCACGTCCGTTCTTCAAGGACCTGGTCGATTTCATGATCTCGGGTCCGGTCGTCGTGCAAGCGCTGGAAGGCGAA
AACGCCATCCTGAAGCATCGTGATCTGATGGGTGCAACGGACCCGAAGAAGGCGGAAAAGGGCACGATCCGCGCCGACTT
CGCAGACAGCATCGACGCGAACGCAGTGCACGGTTCCGACGCGCCTGAAACGGCCGCAGTCGAAATCGCGTTCTTCTTCC
CGCAAGTGAACGTCTACTCGCGCTAA

Upstream 100 bases:

>100_bases
TCTTTCAATGCTGTAAGGGTTCAATCGCAATCATACACGGGAACATGCTACAATAGCGGATTCATTTGAATCTGTAACCT
CTTAATTTTTTGGAGTTTTT

Downstream 100 bases:

>100_bases
GCAGGCCTTGCCGCGCGCGTTTCGTGCAGCCGACCGGATTTATCGCACGAATCGCCCGGCAAAGTAGTAAGGTAAAAGCA
GCAGGAATGGGCGCGAACGG

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MAIERTLSIIKPDAVAKNVIGQIYTRFENAGLKIVASRMVHLSRADAEKFYAVHAARPFFKDLVDFMISGPVVVQALEGE
NAILKHRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETAAVEIAFFFPQVNVYSR

Sequences:

>Translated_141_residues
MAIERTLSIIKPDAVAKNVIGQIYTRFENAGLKIVASRMVHLSRADAEKFYAVHAARPFFKDLVDFMISGPVVVQALEGE
NAILKHRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETAAVEIAFFFPQVNVYSR
>Mature_140_residues
AIERTLSIIKPDAVAKNVIGQIYTRFENAGLKIVASRMVHLSRADAEKFYAVHAARPFFKDLVDFMISGPVVVQALEGEN
AILKHRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETAAVEIAFFFPQVNVYSR

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=130, Percent_Identity=43.0769230769231, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI66392227, Length=131, Percent_Identity=39.6946564885496, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI66392205, Length=131, Percent_Identity=39.6946564885496, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI4505409, Length=131, Percent_Identity=39.6946564885496, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI66392192, Length=131, Percent_Identity=39.6946564885496, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI66392203, Length=131, Percent_Identity=39.6946564885496, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI38045913, Length=131, Percent_Identity=39.6946564885496, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI4557797, Length=131, Percent_Identity=39.6946564885496, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI4826862, Length=130, Percent_Identity=37.6923076923077, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI37574614, Length=139, Percent_Identity=36.6906474820144, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI7019465, Length=139, Percent_Identity=36.6906474820144, Blast_Score=90, Evalue=5e-19,
Organism=Homo sapiens, GI5031951, Length=137, Percent_Identity=37.2262773722628, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI30023828, Length=139, Percent_Identity=33.8129496402878, Blast_Score=79, Evalue=9e-16,
Organism=Homo sapiens, GI4505413, Length=140, Percent_Identity=35.7142857142857, Blast_Score=71, Evalue=3e-13,
Organism=Homo sapiens, GI148839372, Length=129, Percent_Identity=34.8837209302326, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788866, Length=141, Percent_Identity=60.9929078014184, Blast_Score=182, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17506807, Length=139, Percent_Identity=41.0071942446043, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322783, Length=132, Percent_Identity=39.3939393939394, Blast_Score=114, Evalue=5e-27,
Organism=Drosophila melanogaster, GI45549037, Length=130, Percent_Identity=46.1538461538462, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18860097, Length=138, Percent_Identity=32.6086956521739, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15434; Mature: 15303

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIERTLSIIKPDAVAKNVIGQIYTRFENAGLKIVASRMVHLSRADAEKFYAVHAARPFF
CCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
KDLVDFMISGPVVVQALEGENAILKHRDLMGATDPKKAEKGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
APETAAVEIAFFFPQVNVYSR
CCCCCEEEEEEECCCEEECCC
>Mature Secondary Structure 
AIERTLSIIKPDAVAKNVIGQIYTRFENAGLKIVASRMVHLSRADAEKFYAVHAARPFF
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
KDLVDFMISGPVVVQALEGENAILKHRDLMGATDPKKAEKGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
APETAAVEIAFFFPQVNVYSR
CCCCCEEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA