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The map label for this gene is aslA [H]

Identifier: 91783682

GI number: 91783682

Start: 2563672

End: 2565354

Strand: Direct

Name: aslA [H]

Synonym: Bxe_A2132

Alternate gene names: 91783682

Gene position: 2563672-2565354 (Clockwise)

Preceding gene: 91783681

Following gene: 91783683

Centisome position: 52.36

GC content: 60.78

Gene sequence:

>1683_bases
ATGACGAAGTTGTTAAAAAGAGGGCGTTACGCGTTGGGGGCCGGCGCGCTTGCCCTTGCCGCGTTTGGTGCGGTGATTTT
TCCATCCATCAACGCACCGGCCCAAACCCAACCGGCGGCCAAACCCGCCGCCACGAGCGCGCCACAACCGGCCGCGAAGT
CTTCGGCGAAACCGAACATCCTCGTGATTTTCGGCGACGATATCGGGCAGGCGAATATCAGCGCCTACACGCGCGGCGTG
GTCGGCTACAGGACACCGAATATCGACCGTATTGCGAATGAAGGCATGATCTTCACGGACTATTACGCCGAGAACAGTTG
TACGGCAGGCCGCTCTTCCTTCATCACCGGCCAGTCGCCGTTGCGCACCGGGCTGTCCAAGGTCGGCGCACCCGGCGCGC
CGGTTGGTCTGCAAAAGGGCGACATGACAATCGCCCAGGCGCTCAAGCCGCTCGGCTATGCAACCGGCCAGTTCGGCAAG
AATCACCTCGGCGACAAGAACGAGTACCTGCCCACCAATCACGGCTTCGACGAGTTCTACGGCAACCTGTATCACCTGAA
TGCCGAAGAAGAACCGGAGCGCCCTTATTGGCCGAAGGACAAGAACGATCCTTACGTGAAGAACTTCTCGCCGCGCGGCG
TGATTCATAGCACGTCGGACGGCAAGGTTCAGGACACCGGCCCGCTCACGGCCAAACGCATGGAAACCATCGACGACGAA
ACCGGCGCGCACGCGGAGGAATTCATCCGCAAGCAGGTCAAGAATGGCACGCCCTTCTTCGTCTGGATGAACTTCACGCG
AATGCACGTCTTCACCCACGTGCGCCCGGAGTTCAGGGGCAAGAGCGGCATGCCCGGCAACGAATATGCCGACGGCATGT
GGGAGCACGACCAGGATGTCGGCAAACTGCTTAAGTTGCTGGATGACCTGAACATCTCCAAAAACACCATCGTCATTTAC
ACGACGGACAACGGGCCGAACCAGTTCTCGTGGCCCGACGCGGCAACCACGCCGTTCCGCAGCGAGAAGGACTCCAACTG
GGAAGGCGCGTTCCGGGTGCCGGCCATGGTGCGATGGCCGGGGCATATCAAGGCCGGCGAGACGTCCAACGGCATGTTCT
CGGGACTCGACTGGTTCCCCACGCTGCTCGCCGCGGCGGGAGACACCGGTGTAAAGGACCGGCTCCTGAAGGGCTGGGCG
CCCAAGGCGGGTAGCACGAGTTTCAGGAATCACCTCGACGGCTACAACCAGTTGCCGTTCCTGACCGGACAGACCACCAA
GGATCCACGCACGGAGTTCTATTATTTCGACGACGACGGGCAGCTGGTCGCCATGCGCTGGGACCAGGACGGCAACGCGT
GGAAAGCGGTGTTTTGCGAGCAGCGCGCCAAAGGCAACCTGAACATCTGGCAGGACCCGTTCGTCTGCCTGCGAGTGCCC
AAGCTGTTCAACCTGCGCATGGACCCTTATGAACGCGCGGACATCACCTCGGATCAGTACAACGACTGGGTGACGAAGAA
CGTCTATCTGAACGGCATTGCGACACTGAAAGCGTCTGCATTCCTGCAGACCTTCGTCGACTACCCGCCGAGCCAGCGGC
CCGCGAGTTTCAGCGTCGACCAGGTACGCCGGCAGGTCGACAAGAAGATCGACGAGTCGTTCAAGAAGCGCGGACTCGAG
TAA

Upstream 100 bases:

>100_bases
AGTTGAGGCCGTGGAATGCCGGCGGCCGACGAGGGGCGACCCCGTCACGCTGAACACTGCGTAACGGGTGAATAAGAGTC
AACTCCATTGGAGCGACAAA

Downstream 100 bases:

>100_bases
CACGTTCAAGGCGCCGCGCCCGCCGGTTTCGACCGGCAGACGCGGCGCTTGCACGCTTCGCAGCCGAAGTCCATTTACCA
CGTCCCGACTTGCTTCAGCC

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MTKLLKRGRYALGAGALALAAFGAVIFPSINAPAQTQPAAKPAATSAPQPAAKSSAKPNILVIFGDDIGQANISAYTRGV
VGYRTPNIDRIANEGMIFTDYYAENSCTAGRSSFITGQSPLRTGLSKVGAPGAPVGLQKGDMTIAQALKPLGYATGQFGK
NHLGDKNEYLPTNHGFDEFYGNLYHLNAEEEPERPYWPKDKNDPYVKNFSPRGVIHSTSDGKVQDTGPLTAKRMETIDDE
TGAHAEEFIRKQVKNGTPFFVWMNFTRMHVFTHVRPEFRGKSGMPGNEYADGMWEHDQDVGKLLKLLDDLNISKNTIVIY
TTDNGPNQFSWPDAATTPFRSEKDSNWEGAFRVPAMVRWPGHIKAGETSNGMFSGLDWFPTLLAAAGDTGVKDRLLKGWA
PKAGSTSFRNHLDGYNQLPFLTGQTTKDPRTEFYYFDDDGQLVAMRWDQDGNAWKAVFCEQRAKGNLNIWQDPFVCLRVP
KLFNLRMDPYERADITSDQYNDWVTKNVYLNGIATLKASAFLQTFVDYPPSQRPASFSVDQVRRQVDKKIDESFKKRGLE

Sequences:

>Translated_560_residues
MTKLLKRGRYALGAGALALAAFGAVIFPSINAPAQTQPAAKPAATSAPQPAAKSSAKPNILVIFGDDIGQANISAYTRGV
VGYRTPNIDRIANEGMIFTDYYAENSCTAGRSSFITGQSPLRTGLSKVGAPGAPVGLQKGDMTIAQALKPLGYATGQFGK
NHLGDKNEYLPTNHGFDEFYGNLYHLNAEEEPERPYWPKDKNDPYVKNFSPRGVIHSTSDGKVQDTGPLTAKRMETIDDE
TGAHAEEFIRKQVKNGTPFFVWMNFTRMHVFTHVRPEFRGKSGMPGNEYADGMWEHDQDVGKLLKLLDDLNISKNTIVIY
TTDNGPNQFSWPDAATTPFRSEKDSNWEGAFRVPAMVRWPGHIKAGETSNGMFSGLDWFPTLLAAAGDTGVKDRLLKGWA
PKAGSTSFRNHLDGYNQLPFLTGQTTKDPRTEFYYFDDDGQLVAMRWDQDGNAWKAVFCEQRAKGNLNIWQDPFVCLRVP
KLFNLRMDPYERADITSDQYNDWVTKNVYLNGIATLKASAFLQTFVDYPPSQRPASFSVDQVRRQVDKKIDESFKKRGLE
>Mature_559_residues
TKLLKRGRYALGAGALALAAFGAVIFPSINAPAQTQPAAKPAATSAPQPAAKSSAKPNILVIFGDDIGQANISAYTRGVV
GYRTPNIDRIANEGMIFTDYYAENSCTAGRSSFITGQSPLRTGLSKVGAPGAPVGLQKGDMTIAQALKPLGYATGQFGKN
HLGDKNEYLPTNHGFDEFYGNLYHLNAEEEPERPYWPKDKNDPYVKNFSPRGVIHSTSDGKVQDTGPLTAKRMETIDDET
GAHAEEFIRKQVKNGTPFFVWMNFTRMHVFTHVRPEFRGKSGMPGNEYADGMWEHDQDVGKLLKLLDDLNISKNTIVIYT
TDNGPNQFSWPDAATTPFRSEKDSNWEGAFRVPAMVRWPGHIKAGETSNGMFSGLDWFPTLLAAAGDTGVKDRLLKGWAP
KAGSTSFRNHLDGYNQLPFLTGQTTKDPRTEFYYFDDDGQLVAMRWDQDGNAWKAVFCEQRAKGNLNIWQDPFVCLRVPK
LFNLRMDPYERADITSDQYNDWVTKNVYLNGIATLKASAFLQTFVDYPPSQRPASFSVDQVRRQVDKKIDESFKKRGLE

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=494, Percent_Identity=30.1619433198381, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI146229331, Length=456, Percent_Identity=30.0438596491228, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI146229329, Length=456, Percent_Identity=30.0438596491228, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI6005990, Length=456, Percent_Identity=30.0438596491228, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI146229324, Length=456, Percent_Identity=30.0438596491228, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI45430057, Length=359, Percent_Identity=30.08356545961, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI157266309, Length=527, Percent_Identity=28.4629981024668, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI31742482, Length=538, Percent_Identity=26.7657992565056, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI58743319, Length=529, Percent_Identity=27.5992438563327, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI109389362, Length=510, Percent_Identity=24.9019607843137, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI59797060, Length=475, Percent_Identity=26.1052631578947, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI38569407, Length=347, Percent_Identity=27.0893371757925, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI38569405, Length=347, Percent_Identity=27.0893371757925, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI146229327, Length=376, Percent_Identity=28.1914893617021, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI53831991, Length=286, Percent_Identity=26.5734265734266, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI71852586, Length=160, Percent_Identity=36.25, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI71852584, Length=160, Percent_Identity=36.25, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1790233, Length=525, Percent_Identity=30.0952380952381, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081924, Length=377, Percent_Identity=23.0769230769231, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115533416, Length=464, Percent_Identity=26.0775862068966, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI115533418, Length=434, Percent_Identity=26.036866359447, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559078, Length=243, Percent_Identity=29.6296296296296, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363223, Length=351, Percent_Identity=29.6296296296296, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666175, Length=405, Percent_Identity=26.4197530864197, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281366397, Length=352, Percent_Identity=28.9772727272727, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281366395, Length=352, Percent_Identity=28.9772727272727, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666163, Length=352, Percent_Identity=28.9772727272727, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666109, Length=428, Percent_Identity=26.6355140186916, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 62294; Mature: 62162

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLLKRGRYALGAGALALAAFGAVIFPSINAPAQTQPAAKPAATSAPQPAAKSSAKPNI
CCHHHHCCCCHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCE
LVIFGDDIGQANISAYTRGVVGYRTPNIDRIANEGMIFTDYYAENSCTAGRSSFITGQSP
EEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCEECCCHH
LRTGLSKVGAPGAPVGLQKGDMTIAQALKPLGYATGQFGKNHLGDKNEYLPTNHGFDEFY
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHC
GNLYHLNAEEEPERPYWPKDKNDPYVKNFSPRGVIHSTSDGKVQDTGPLTAKRMETIDDE
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHCCC
TGAHAEEFIRKQVKNGTPFFVWMNFTRMHVFTHVRPEFRGKSGMPGNEYADGMWEHDQDV
CCCHHHHHHHHHHCCCCCEEEEECCEEEEEHHHCCHHHCCCCCCCCCHHCCCCCCCHHHH
GKLLKLLDDLNISKNTIVIYTTDNGPNQFSWPDAATTPFRSEKDSNWEGAFRVPAMVRWP
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEECC
GHIKAGETSNGMFSGLDWFPTLLAAAGDTGVKDRLLKGWAPKAGSTSFRNHLDGYNQLPF
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCCE
LTGQTTKDPRTEFYYFDDDGQLVAMRWDQDGNAWKAVFCEQRAKGNLNIWQDPFVCLRVP
ECCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEHEEEHHHCCCCCCCCCCCEEEEECC
KLFNLRMDPYERADITSDQYNDWVTKNVYLNGIATLKASAFLQTFVDYPPSQRPASFSVD
HHHCCCCCCCHHCCCCCCCCCCCEECEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
QVRRQVDKKIDESFKKRGLE
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKLLKRGRYALGAGALALAAFGAVIFPSINAPAQTQPAAKPAATSAPQPAAKSSAKPNI
CHHHHCCCCHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCE
LVIFGDDIGQANISAYTRGVVGYRTPNIDRIANEGMIFTDYYAENSCTAGRSSFITGQSP
EEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCEECCCHH
LRTGLSKVGAPGAPVGLQKGDMTIAQALKPLGYATGQFGKNHLGDKNEYLPTNHGFDEFY
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHC
GNLYHLNAEEEPERPYWPKDKNDPYVKNFSPRGVIHSTSDGKVQDTGPLTAKRMETIDDE
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHCCC
TGAHAEEFIRKQVKNGTPFFVWMNFTRMHVFTHVRPEFRGKSGMPGNEYADGMWEHDQDV
CCCHHHHHHHHHHCCCCCEEEEECCEEEEEHHHCCHHHCCCCCCCCCHHCCCCCCCHHHH
GKLLKLLDDLNISKNTIVIYTTDNGPNQFSWPDAATTPFRSEKDSNWEGAFRVPAMVRWP
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEECC
GHIKAGETSNGMFSGLDWFPTLLAAAGDTGVKDRLLKGWAPKAGSTSFRNHLDGYNQLPF
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCCE
LTGQTTKDPRTEFYYFDDDGQLVAMRWDQDGNAWKAVFCEQRAKGNLNIWQDPFVCLRVP
ECCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEHEEEHHHCCCCCCCCCCCEEEEECC
KLFNLRMDPYERADITSDQYNDWVTKNVYLNGIATLKASAFLQTFVDYPPSQRPASFSVD
HHHCCCCCCCHHCCCCCCCCCCCEECEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
QVRRQVDKKIDESFKKRGLE
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]