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The map label for this gene is dusC [H]

Identifier: 91783478

GI number: 91783478

Start: 2323292

End: 2324314

Strand: Direct

Name: dusC [H]

Synonym: Bxe_A2338

Alternate gene names: 91783478

Gene position: 2323292-2324314 (Clockwise)

Preceding gene: 91783477

Following gene: 91783479

Centisome position: 47.45

GC content: 66.67

Gene sequence:

>1023_bases
ATGAGCCGCATCTATCTCGCCCCAATGGAAGGCCTCGCCGACTACGTATTGCGCGACGTGCTGACCGGCATCGGCGGATT
CGATGGATGCGTGTCCGAGTTCGTCCGCGTGACGGGCTCCCTGCTGCCCAGCCGAGTCTACGAAAGAGAAGCGCCCGAAG
TGCTCGACGGAGGTCACACGCCCAATGGCACGCCGATGGTGATCCAGCTGCTCGGCAGCGATCCCGAATGGATGGCGCGG
AATGCCGCCCACGCGGCCAGCCTGTCGCCGCATGGAATCGACCTGAACTTCGGATGTCCCGCCAAGGTCGTCAATCAGCA
CGGCGGCGGCGCCATGTTGCTGGCCGACCCTGAACAACTGAACCGGATCGTGTCGTCGGTACGGGCCGCCGTGCCCGCCG
GTGTCCCCGTGACGGCAAAAATGCGCCTTGGCGTGTCCGACACGTCGCTGGCGATCGAATGCGCAGTCGCGCTCGCGGAA
GGCGGCGCCGCCTCGCTCGTCGTGCACGCCAGAACGCGCGATCACGGCTACCGGCCGCCGGCCCACTGGGAGTGGATCGC
GCGGATCGATGCCGCCGTGGACGTGCCGGTCGTCGCGAACGGCGAGGTATGGACGGTGGCCGACTGGGAGCGCTGCCGCG
CGGTCAGCGGCTGCGCGAACGTCATGCTCGGGCGGGGCGCCGTGTCGGACCCGTTCCTGGCACTGAGAATACGCGGCCTG
ATGGAGCGGACCCCGTCCCACGGGGAATGGCGGCACGTGCTGGGCCACATCGCCGGTTATCTGAGGAAATTGCAGACGCG
CGTCGCATCGCGTCATGAGCACGGGCGGGTCAAAAAGTGGCTCAGCTACCTGCAGCGCACCTGGCCGCAGGCGGCCGAGC
TGCATGCGGCGATCCGCCGGGTGCAGGATTCGCACGAAATTCTGGCGATGATCGAACGCGCATTGGGATTCGATGAATTA
ATGGCGACGCATCGATTCGCGTCCGCCAGTCAACTCGACGTAGCGGACCTCGCAGCCGGTTGA

Upstream 100 bases:

>100_bases
CGCCACAGTTGTTTCAGTTCTATCAATCGATTCGACCCATGTTCCTTACACGCTACGCCTGCCGTCCCGAACGGGGTCAA
CCGCCTGTGACCGCGCCAGC

Downstream 100 bases:

>100_bases
AGGCGAAAATTCAAAGACTTACGAGCGGCAGCCCTGGCGAACCGCTACAATTCAGGGTTTAACGTCTTCAAGCGGTTCCC
CATGTCTGCCACCCCACCGA

Product: putative tRNA-dihydrouridine synthase C, DuS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSRIYLAPMEGLADYVLRDVLTGIGGFDGCVSEFVRVTGSLLPSRVYEREAPEVLDGGHTPNGTPMVIQLLGSDPEWMAR
NAAHAASLSPHGIDLNFGCPAKVVNQHGGGAMLLADPEQLNRIVSSVRAAVPAGVPVTAKMRLGVSDTSLAIECAVALAE
GGAASLVVHARTRDHGYRPPAHWEWIARIDAAVDVPVVANGEVWTVADWERCRAVSGCANVMLGRGAVSDPFLALRIRGL
MERTPSHGEWRHVLGHIAGYLRKLQTRVASRHEHGRVKKWLSYLQRTWPQAAELHAAIRRVQDSHEILAMIERALGFDEL
MATHRFASASQLDVADLAAG

Sequences:

>Translated_340_residues
MSRIYLAPMEGLADYVLRDVLTGIGGFDGCVSEFVRVTGSLLPSRVYEREAPEVLDGGHTPNGTPMVIQLLGSDPEWMAR
NAAHAASLSPHGIDLNFGCPAKVVNQHGGGAMLLADPEQLNRIVSSVRAAVPAGVPVTAKMRLGVSDTSLAIECAVALAE
GGAASLVVHARTRDHGYRPPAHWEWIARIDAAVDVPVVANGEVWTVADWERCRAVSGCANVMLGRGAVSDPFLALRIRGL
MERTPSHGEWRHVLGHIAGYLRKLQTRVASRHEHGRVKKWLSYLQRTWPQAAELHAAIRRVQDSHEILAMIERALGFDEL
MATHRFASASQLDVADLAAG
>Mature_339_residues
SRIYLAPMEGLADYVLRDVLTGIGGFDGCVSEFVRVTGSLLPSRVYEREAPEVLDGGHTPNGTPMVIQLLGSDPEWMARN
AAHAASLSPHGIDLNFGCPAKVVNQHGGGAMLLADPEQLNRIVSSVRAAVPAGVPVTAKMRLGVSDTSLAIECAVALAEG
GAASLVVHARTRDHGYRPPAHWEWIARIDAAVDVPVVANGEVWTVADWERCRAVSGCANVMLGRGAVSDPFLALRIRGLM
ERTPSHGEWRHVLGHIAGYLRKLQTRVASRHEHGRVKKWLSYLQRTWPQAAELHAAIRRVQDSHEILAMIERALGFDELM
ATHRFASASQLDVADLAAG

Specific function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs [H]

COG id: COG0042

COG function: function code J; tRNA-dihydrouridine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dus family. DusC subfamily [H]

Homologues:

Organism=Homo sapiens, GI239788483, Length=297, Percent_Identity=26.2626262626263, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40807366, Length=198, Percent_Identity=31.3131313131313, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI239788462, Length=297, Percent_Identity=26.2626262626263, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI31742496, Length=179, Percent_Identity=28.4916201117318, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI8923374, Length=159, Percent_Identity=32.0754716981132, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788462, Length=319, Percent_Identity=40.7523510971787, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1789660, Length=245, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17510279, Length=292, Percent_Identity=26.7123287671233, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507177, Length=175, Percent_Identity=30.2857142857143, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25144369, Length=171, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543114, Length=242, Percent_Identity=23.5537190082645, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323560, Length=192, Percent_Identity=27.6041666666667, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323437, Length=203, Percent_Identity=26.6009852216749, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323433, Length=167, Percent_Identity=26.3473053892216, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585320, Length=231, Percent_Identity=32.034632034632, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24580595, Length=175, Percent_Identity=31.4285714285714, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920448, Length=175, Percent_Identity=31.4285714285714, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549423, Length=139, Percent_Identity=35.2517985611511, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921524, Length=177, Percent_Identity=28.8135593220339, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001269
- InterPro:   IPR018517 [H]

Pfam domain/function: PF01207 Dus [H]

EC number: NA

Molecular weight: Translated: 36780; Mature: 36648

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS01136 UPF0034

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIYLAPMEGLADYVLRDVLTGIGGFDGCVSEFVRVTGSLLPSRVYEREAPEVLDGGHT
CCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
PNGTPMVIQLLGSDPEWMARNAAHAASLSPHGIDLNFGCPAKVVNQHGGGAMLLADPEQL
CCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHCCCCCEEEEECHHHH
NRIVSSVRAAVPAGVPVTAKMRLGVSDTSLAIECAVALAEGGAASLVVHARTRDHGYRPP
HHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
AHWEWIARIDAAVDVPVVANGEVWTVADWERCRAVSGCANVMLGRGAVSDPFLALRIRGL
CCHHHHHHHHHHCCCCEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MERTPSHGEWRHVLGHIAGYLRKLQTRVASRHEHGRVKKWLSYLQRTWPQAAELHAAIRR
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHH
VQDSHEILAMIERALGFDELMATHRFASASQLDVADLAAG
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure 
SRIYLAPMEGLADYVLRDVLTGIGGFDGCVSEFVRVTGSLLPSRVYEREAPEVLDGGHT
CCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
PNGTPMVIQLLGSDPEWMARNAAHAASLSPHGIDLNFGCPAKVVNQHGGGAMLLADPEQL
CCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHCCCCCEEEEECHHHH
NRIVSSVRAAVPAGVPVTAKMRLGVSDTSLAIECAVALAEGGAASLVVHARTRDHGYRPP
HHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
AHWEWIARIDAAVDVPVVANGEVWTVADWERCRAVSGCANVMLGRGAVSDPFLALRIRGL
CCHHHHHHHHHHCCCCEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MERTPSHGEWRHVLGHIAGYLRKLQTRVASRHEHGRVKKWLSYLQRTWPQAAELHAAIRR
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHH
VQDSHEILAMIERALGFDELMATHRFASASQLDVADLAAG
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9555876 [H]