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The map label for this gene is hisQ [H]

Identifier: 91782895

GI number: 91782895

Start: 1690329

End: 1691030

Strand: Direct

Name: hisQ [H]

Synonym: Bxe_A2927

Alternate gene names: 91782895

Gene position: 1690329-1691030 (Clockwise)

Preceding gene: 91782894

Following gene: 91782896

Centisome position: 34.53

GC content: 63.96

Gene sequence:

>702_bases
ATGGAGACACGCGTGTTCCTATATGGCTTTGGTCCGGTGCTGCTGGCCGGCACGATCCAGACGATCGAGCTGTCCGTCCT
GTCGCTCGTGGCCGCCGTGCTGCTCGGCCTCGCGGGCGCGGCGGCGAAACTCTCGTTCAGTCGCCCGCTGCGCGCAATCG
CCACCGGCTACACGACGCTGATCCGCTCGGTGCCCGACCTCGTGCTAATGCTGCTGCTGTTCTACAGCATCCAGATCGCG
GTGAACGATCTCACCGACGCGCTGAATCTGCCGCAGTTCGATATCGATCCGTTCGTGGCCGGCGTGCTGACGCTCGGCTT
CATTTACGGCGCGTACTTCACCGAGACGTTCCGCGGCGCGTTTCTGGCCGTGCCGCGTGGCCAGCTCGAAGCGGGCAGCG
CGTACGGCATGAGCGGCGCGCGCGTGTTCACGCGCATCCTGTTTCCGCAGATGATGCGCTTCGCGCTGCCGGGCATCGGC
AACAACTGGCAGGTGCTGGTGAAGGCCACCGCGCTGGTGTCGATCATCGGTCTCGCCGACGTGGTCAAAGCCGCGCAGGA
CGCCGGCAAAAGCACCTTCAACATGTTCTTCTTCATCCTGATCGCCGCGCTGATCTATCTGGCTATCACCACCGTGTCGA
ATCTCGTGCTGATCTGGCTGGAAAAGCGCTATTCGACCGGCGTGCGGCACGCGGAGCTCTGA

Upstream 100 bases:

>100_bases
AGAATTTAATTTTCGCCTGCGAGACTCCGCGCCATGCCGGACGGGTGGGGCGGACACACACACAAGCCGACGCCGTCCGG
CACATCGTCAAACAACCTGG

Downstream 100 bases:

>100_bases
GACCATGATCGATATTCTCAATCAGTTCTGGCGCGCGTTCCTCTACTGGGACGGCCAGCGCATGTCGGGTCTCGCGGTCA
CGCTGTGGCTGCTGGTGGCA

Product: ABC lysine/arginine/ornithine transporter, innermembrane subunit

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
METRVFLYGFGPVLLAGTIQTIELSVLSLVAAVLLGLAGAAAKLSFSRPLRAIATGYTTLIRSVPDLVLMLLLFYSIQIA
VNDLTDALNLPQFDIDPFVAGVLTLGFIYGAYFTETFRGAFLAVPRGQLEAGSAYGMSGARVFTRILFPQMMRFALPGIG
NNWQVLVKATALVSIIGLADVVKAAQDAGKSTFNMFFFILIAALIYLAITTVSNLVLIWLEKRYSTGVRHAEL

Sequences:

>Translated_233_residues
METRVFLYGFGPVLLAGTIQTIELSVLSLVAAVLLGLAGAAAKLSFSRPLRAIATGYTTLIRSVPDLVLMLLLFYSIQIA
VNDLTDALNLPQFDIDPFVAGVLTLGFIYGAYFTETFRGAFLAVPRGQLEAGSAYGMSGARVFTRILFPQMMRFALPGIG
NNWQVLVKATALVSIIGLADVVKAAQDAGKSTFNMFFFILIAALIYLAITTVSNLVLIWLEKRYSTGVRHAEL
>Mature_233_residues
METRVFLYGFGPVLLAGTIQTIELSVLSLVAAVLLGLAGAAAKLSFSRPLRAIATGYTTLIRSVPDLVLMLLLFYSIQIA
VNDLTDALNLPQFDIDPFVAGVLTLGFIYGAYFTETFRGAFLAVPRGQLEAGSAYGMSGARVFTRILFPQMMRFALPGIG
NNWQVLVKATALVSIIGLADVVKAAQDAGKSTFNMFFFILIAALIYLAITTVSNLVLIWLEKRYSTGVRHAEL

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=62.1145374449339, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI1787087, Length=210, Percent_Identity=34.2857142857143, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1787030, Length=212, Percent_Identity=31.6037735849057, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788226, Length=223, Percent_Identity=29.5964125560538, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786873, Length=213, Percent_Identity=30.5164319248826, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788645, Length=213, Percent_Identity=31.4553990610329, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787086, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786874, Length=215, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082239, Length=223, Percent_Identity=27.8026905829596, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25208; Mature: 25208

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRVFLYGFGPVLLAGTIQTIELSVLSLVAAVLLGLAGAAAKLSFSRPLRAIATGYTTL
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IRSVPDLVLMLLLFYSIQIAVNDLTDALNLPQFDIDPFVAGVLTLGFIYGAYFTETFRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
FLAVPRGQLEAGSAYGMSGARVFTRILFPQMMRFALPGIGNNWQVLVKATALVSIIGLAD
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
VVKAAQDAGKSTFNMFFFILIAALIYLAITTVSNLVLIWLEKRYSTGVRHAEL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
METRVFLYGFGPVLLAGTIQTIELSVLSLVAAVLLGLAGAAAKLSFSRPLRAIATGYTTL
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IRSVPDLVLMLLLFYSIQIAVNDLTDALNLPQFDIDPFVAGVLTLGFIYGAYFTETFRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
FLAVPRGQLEAGSAYGMSGARVFTRILFPQMMRFALPGIGNNWQVLVKATALVSIIGLAD
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
VVKAAQDAGKSTFNMFFFILIAALIYLAITTVSNLVLIWLEKRYSTGVRHAEL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]