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The map label for this gene is nuoL [H]

Identifier: 91782623

GI number: 91782623

Start: 1392325

End: 1394403

Strand: Direct

Name: nuoL [H]

Synonym: Bxe_A3203

Alternate gene names: 91782623

Gene position: 1392325-1394403 (Clockwise)

Preceding gene: 91782622

Following gene: 91782624

Centisome position: 28.44

GC content: 61.23

Gene sequence:

>2079_bases
ATGTCCACGATACTCAATGAAAACCTGCTGCTGGCGATTCCGCTGGCGCCGCTGGCCGGCTGTCTGGTTGCCGGGCTGTT
CGGAAAAGCGGTAGGGCGAGCCGGTGCGCATTCGGTCACGATCCTCGGCGTCGCGATCTCGTTCATTCTTTCGGCCATCG
TCTTCTTCCAGGTGATGGACGGCGCGAGCTTCAACGCGACCGTCTACGAATGGATGTCGATCGGCAAGACGAAGTTCGAG
GTCGGCTTCCTGGTCGACTCGCTGACGGCCATGATGATGTGCGTGGTGACCTTCGTGTCGCTGATGGTGCACATCTACAC
GATCGGCTACATGGCCGACGACGACGGCTACCAGCGCTTCTTCTCGTACATTTCGCTCTTCACGTTCTCGATGTTGATGC
TCGTGATGAGCAACAACTTCCTGCAGCTGTTCTTCGGCTGGGAAGCGGTGGGTCTGGTGTCGTACCTGCTGATCGGCTTC
TACTTCACGCGTCCCACGGCGATCTACGCGAACATGAAGGCGTTCATCGTGAACCGCATCGGCGACTTCGGCTTTCTGCT
GGGTATCGGCCTGCTGTTCGCGTTCGCCGGTTCGATGAACTACGGCGACGTGTTTGCGAAGCGCACCGAACTCGCGGCAT
TGACCTTTCCGGGTACGGACTGGGGTCTGCTGACGGTGGCCTGTATTTGCCTCTTCATCGGCGCAATGGGTAAGTCGGCG
CAGTTCCCGCTGCACGTCTGGCTGCCGGATTCGATGGAAGGCCCGACGCCGATTTCCGCGCTGATTCACGCGGCAACCAT
GGTGACGGCCGGTATCTTCATGGTCACGCGCATGTCGCCGCTGTTCGAACTGTCGGATACGGCGCTCTCGTTCGTGACGG
TCATCGGCGCGATTACCGCGCTGTTCATGGGCTTCCTCGGGATCGTGCAGAACGACATCAAGCGCGTGGTGGCTTACTCC
ACGCTGTCGCAGCTCGGTTACATGACGGTGGCGCTCGGCGTGTCGGCTTACCCGGTCGCCGTGTTCCACCTGATGACGCA
CGCGTTCTTCAAGGCGCTGCTGTTCCTCGGCGCGGGTTCGGTGATCATCGGCATGCACCACGATCAGGACATGCGCAACA
TGGGCGGCCTGCGCAAGTACATGCCGATCACGTGGATCACGTCGCTGATCGGTTCGCTGGCGCTGATCGGTACGCCGTTC
TTCTCGGGCTTCTATTCGAAAGACTCGATCATCGACGCAGTGAAGCTCTCGCATCTGCCGGGTTCGGGCTTCGCGTACTT
CGCGGTGGTGGCGAGCGTCTTCGTGACTGCGCTGTATTCGTTCCGTATGTACTTCATGGTGTTCCACGGCAAGGAGCGCT
TCCGCGATCCGAAGCATCCGGATTCGCCGATGGGTGCCGAAGCCGCCGCCCATGCGCATGACGCGCACGGCCACGACGCG
CACGGCCACGGCCACGGCCACGGTCACGACGACCACGCACACGAGCCGCACGAAACGCCGTGGGTGGTGTGGCTGCCGCT
GGTGCTGCTGGCGATCCCGTCGGTGGTGATCGGCGCGATCGGCGTGGGTCCCATGCTGTTCGGCGACTTCTTCCAGCACG
GCGTGGCGTTCGACAAGGTGATCTTCATCGGCGAAAACCATCCGGCGCTTCATGAGATGGCTGAAGAGTTCCAGGGCTGG
GCGTCGATGGGTCTGCACTCGGTCGCGGGTCTGCCGGTCTGGCTGGCGCTCGCGGGTGTGGTGGTCGCATGGTTCCTGTA
CCTGATCCGTCCGGATTTGCCGGCTGTCATCAAGCGCGCATTCGGCCCGATCTACACGTTGCTCGATAACAAGTACTACC
TGGACAAGATCAACGATGTCGTGTTTGCGCGGGGCGCCGTGGCAATTGGCCGTGGTCTCTGGAAGGAAGGCGACGTCGTG
GTGATCGACGGCATCGTCAACGGCAGCGCACGCTTTATCGGCTGGTTCGCCGGCGTGATCCGCTTCCTCCAATCCGGCTA
CATCTACCACTACGCGTTCGCCATGATTATCGGCATGTTGGGGCTCCTGACCCTGTTTGTAACGCTCGGCGGCAAATAA

Upstream 100 bases:

>100_bases
CAATCGGCCTCGCGATTCTGGTGACCCTGTTCCGTAGCCTCGACACGATCAATGTCGAGGATCTCGATCAGCTCAAAGGT
TAATTTCAGGAAAAGCGGTT

Downstream 100 bases:

>100_bases
GGCGAGGGACACTAATGCACGCTTATCCGATTCTCAGCATCGCAATCTGGTTACCGATTCTCGTCGGCCTGCTGGTCCTC
GCTATCGGTTCGGACCGGAA

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MSTILNENLLLAIPLAPLAGCLVAGLFGKAVGRAGAHSVTILGVAISFILSAIVFFQVMDGASFNATVYEWMSIGKTKFE
VGFLVDSLTAMMMCVVTFVSLMVHIYTIGYMADDDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGF
YFTRPTAIYANMKAFIVNRIGDFGFLLGIGLLFAFAGSMNYGDVFAKRTELAALTFPGTDWGLLTVACICLFIGAMGKSA
QFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDTALSFVTVIGAITALFMGFLGIVQNDIKRVVAYS
TLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLGAGSVIIGMHHDQDMRNMGGLRKYMPITWITSLIGSLALIGTPF
FSGFYSKDSIIDAVKLSHLPGSGFAYFAVVASVFVTALYSFRMYFMVFHGKERFRDPKHPDSPMGAEAAAHAHDAHGHDA
HGHGHGHGHDDHAHEPHETPWVVWLPLVLLAIPSVVIGAIGVGPMLFGDFFQHGVAFDKVIFIGENHPALHEMAEEFQGW
ASMGLHSVAGLPVWLALAGVVVAWFLYLIRPDLPAVIKRAFGPIYTLLDNKYYLDKINDVVFARGAVAIGRGLWKEGDVV
VIDGIVNGSARFIGWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK

Sequences:

>Translated_692_residues
MSTILNENLLLAIPLAPLAGCLVAGLFGKAVGRAGAHSVTILGVAISFILSAIVFFQVMDGASFNATVYEWMSIGKTKFE
VGFLVDSLTAMMMCVVTFVSLMVHIYTIGYMADDDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGF
YFTRPTAIYANMKAFIVNRIGDFGFLLGIGLLFAFAGSMNYGDVFAKRTELAALTFPGTDWGLLTVACICLFIGAMGKSA
QFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDTALSFVTVIGAITALFMGFLGIVQNDIKRVVAYS
TLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLGAGSVIIGMHHDQDMRNMGGLRKYMPITWITSLIGSLALIGTPF
FSGFYSKDSIIDAVKLSHLPGSGFAYFAVVASVFVTALYSFRMYFMVFHGKERFRDPKHPDSPMGAEAAAHAHDAHGHDA
HGHGHGHGHDDHAHEPHETPWVVWLPLVLLAIPSVVIGAIGVGPMLFGDFFQHGVAFDKVIFIGENHPALHEMAEEFQGW
ASMGLHSVAGLPVWLALAGVVVAWFLYLIRPDLPAVIKRAFGPIYTLLDNKYYLDKINDVVFARGAVAIGRGLWKEGDVV
VIDGIVNGSARFIGWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK
>Mature_691_residues
STILNENLLLAIPLAPLAGCLVAGLFGKAVGRAGAHSVTILGVAISFILSAIVFFQVMDGASFNATVYEWMSIGKTKFEV
GFLVDSLTAMMMCVVTFVSLMVHIYTIGYMADDDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFY
FTRPTAIYANMKAFIVNRIGDFGFLLGIGLLFAFAGSMNYGDVFAKRTELAALTFPGTDWGLLTVACICLFIGAMGKSAQ
FPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDTALSFVTVIGAITALFMGFLGIVQNDIKRVVAYST
LSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLGAGSVIIGMHHDQDMRNMGGLRKYMPITWITSLIGSLALIGTPFF
SGFYSKDSIIDAVKLSHLPGSGFAYFAVVASVFVTALYSFRMYFMVFHGKERFRDPKHPDSPMGAEAAAHAHDAHGHDAH
GHGHGHGHDDHAHEPHETPWVVWLPLVLLAIPSVVIGAIGVGPMLFGDFFQHGVAFDKVIFIGENHPALHEMAEEFQGWA
SMGLHSVAGLPVWLALAGVVVAWFLYLIRPDLPAVIKRAFGPIYTLLDNKYYLDKINDVVFARGAVAIGRGLWKEGDVVV
IDGIVNGSARFIGWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=413, Percent_Identity=39.7094430992736, Blast_Score=287, Evalue=3e-77,
Organism=Escherichia coli, GI1788614, Length=465, Percent_Identity=42.7956989247312, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI1788829, Length=414, Percent_Identity=29.4685990338164, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1788831, Length=352, Percent_Identity=29.5454545454545, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1788827, Length=407, Percent_Identity=29.4840294840295, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI2367154, Length=189, Percent_Identity=30.1587301587302, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI145693160, Length=318, Percent_Identity=24.5283018867925, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788613, Length=395, Percent_Identity=24.0506329113924, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75425; Mature: 75293

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTILNENLLLAIPLAPLAGCLVAGLFGKAVGRAGAHSVTILGVAISFILSAIVFFQVMD
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GASFNATVYEWMSIGKTKFEVGFLVDSLTAMMMCVVTFVSLMVHIYTIGYMADDDGYQRF
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHH
FSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFTRPTAIYANMKAFIVNRI
HHHHHHHHHHHHHHHHCCCCEEEHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GDFGFLLGIGLLFAFAGSMNYGDVFAKRTELAALTFPGTDWGLLTVACICLFIGAMGKSA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
QFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDTALSFVTVIGAITA
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFMGFLGIVQNDIKRVVAYSTLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VIIGMHHDQDMRNMGGLRKYMPITWITSLIGSLALIGTPFFSGFYSKDSIIDAVKLSHLP
EEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHCCC
GSGFAYFAVVASVFVTALYSFRMYFMVFHGKERFRDPKHPDSPMGAEAAAHAHDAHGHDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHCCCCCCCCC
HGHGHGHGHDDHAHEPHETPWVVWLPLVLLAIPSVVIGAIGVGPMLFGDFFQHGVAFDKV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
IFIGENHPALHEMAEEFQGWASMGLHSVAGLPVWLALAGVVVAWFLYLIRPDLPAVIKRA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FGPIYTLLDNKYYLDKINDVVFARGAVAIGRGLWKEGDVVVIDGIVNGSARFIGWFAGVI
HHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEECEECCCHHHHHHHHHHH
RFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STILNENLLLAIPLAPLAGCLVAGLFGKAVGRAGAHSVTILGVAISFILSAIVFFQVMD
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GASFNATVYEWMSIGKTKFEVGFLVDSLTAMMMCVVTFVSLMVHIYTIGYMADDDGYQRF
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHH
FSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFTRPTAIYANMKAFIVNRI
HHHHHHHHHHHHHHHHCCCCEEEHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GDFGFLLGIGLLFAFAGSMNYGDVFAKRTELAALTFPGTDWGLLTVACICLFIGAMGKSA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
QFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDTALSFVTVIGAITA
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFMGFLGIVQNDIKRVVAYSTLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VIIGMHHDQDMRNMGGLRKYMPITWITSLIGSLALIGTPFFSGFYSKDSIIDAVKLSHLP
EEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHCCC
GSGFAYFAVVASVFVTALYSFRMYFMVFHGKERFRDPKHPDSPMGAEAAAHAHDAHGHDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHCCCCCCCCC
HGHGHGHGHDDHAHEPHETPWVVWLPLVLLAIPSVVIGAIGVGPMLFGDFFQHGVAFDKV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
IFIGENHPALHEMAEEFQGWASMGLHSVAGLPVWLALAGVVVAWFLYLIRPDLPAVIKRA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FGPIYTLLDNKYYLDKINDVVFARGAVAIGRGLWKEGDVVVIDGIVNGSARFIGWFAGVI
HHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEECEECCCHHHHHHHHHHH
RFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]