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The map label for this gene is nuoE2 [H]

Identifier: 91782616

GI number: 91782616

Start: 1385263

End: 1385748

Strand: Direct

Name: nuoE2 [H]

Synonym: Bxe_A3210

Alternate gene names: 91782616

Gene position: 1385263-1385748 (Clockwise)

Preceding gene: 91782615

Following gene: 91782617

Centisome position: 28.29

GC content: 60.08

Gene sequence:

>486_bases
ATGATCTCAGCTGAAGGCCTGAAAGAAATCGATCGTGCGATCGCGAAGTATCCCGCCGATCAGAAACAGTCCGCCGTGAT
GTCGGCGTTGGCCACTGCTCAGGAAGAGCATGGCTGGCTGTCGCCCGAACTCATGCAGTTCGTCGCGGACTATCTCGGCA
TGCCGGCAGTCGCCGTGCAGGAGGTGGCCACCTTCTACACGATGTACGAGACCTCGCCGGTCGGCAAGTACAAGATCACG
CTCTGCACGAACCTGCCGTGTCAGCTTGGCCCGGACGGCGGCTCGGACAGCGCGGCTGAATATCTGAAGCAGAAGCTCGG
CATCGACTTCGGCGAAACCACGCCCGACGGCAAGTTCACCCTGAAAGAAGGTGAGTGCATGGGCTCGTGCGGCGACGCGC
CGGTGATGCTGGTGAACAACCATCGCATGTGCAGCTTCATGAGCCGCGCGAAGATCGACCAGCTGCTCGAGGAACTTTCG
AAATGA

Upstream 100 bases:

>100_bases
CACCGAAGCGCGCGGCAAGCAAAGGAACGCCGGGTCTGTCGCAGCATGATGTGAGCGACGGGTTTTCGTTCGGTAGGAAT
TGAAAGAGTCGTGTCTGAAA

Downstream 100 bases:

>100_bases
CGTGTTTACACGATCGTCACATCAAACCGCTGATTCTCGCCGGCCTGAACGGCGATAACTGGCATCTCGAAGACTATGTG
GCGCGCGGCGGTTACGCCCA

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E 2; NDH-1 subunit E 2 [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MISAEGLKEIDRAIAKYPADQKQSAVMSALATAQEEHGWLSPELMQFVADYLGMPAVAVQEVATFYTMYETSPVGKYKIT
LCTNLPCQLGPDGGSDSAAEYLKQKLGIDFGETTPDGKFTLKEGECMGSCGDAPVMLVNNHRMCSFMSRAKIDQLLEELS
K

Sequences:

>Translated_161_residues
MISAEGLKEIDRAIAKYPADQKQSAVMSALATAQEEHGWLSPELMQFVADYLGMPAVAVQEVATFYTMYETSPVGKYKIT
LCTNLPCQLGPDGGSDSAAEYLKQKLGIDFGETTPDGKFTLKEGECMGSCGDAPVMLVNNHRMCSFMSRAKIDQLLEELS
K
>Mature_161_residues
MISAEGLKEIDRAIAKYPADQKQSAVMSALATAQEEHGWLSPELMQFVADYLGMPAVAVQEVATFYTMYETSPVGKYKIT
LCTNLPCQLGPDGGSDSAAEYLKQKLGIDFGETTPDGKFTLKEGECMGSCGDAPVMLVNNHRMCSFMSRAKIDQLLEELS
K

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=158, Percent_Identity=43.0379746835443, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1788621, Length=156, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561328, Length=158, Percent_Identity=37.9746835443038, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI18859877, Length=139, Percent_Identity=43.1654676258993, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21355353, Length=139, Percent_Identity=38.8489208633094, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17543; Mature: 17543

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAEGLKEIDRAIAKYPADQKQSAVMSALATAQEEHGWLSPELMQFVADYLGMPAVAVQ
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHH
EVATFYTMYETSPVGKYKITLCTNLPCQLGPDGGSDSAAEYLKQKLGIDFGETTPDGKFT
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEE
LKEGECMGSCGDAPVMLVNNHRMCSFMSRAKIDQLLEELSK
EECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISAEGLKEIDRAIAKYPADQKQSAVMSALATAQEEHGWLSPELMQFVADYLGMPAVAVQ
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHH
EVATFYTMYETSPVGKYKITLCTNLPCQLGPDGGSDSAAEYLKQKLGIDFGETTPDGKFT
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEE
LKEGECMGSCGDAPVMLVNNHRMCSFMSRAKIDQLLEELSK
EECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]