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The map label for this gene is nuoD [H]

Identifier: 91782615

GI number: 91782615

Start: 1383878

End: 1385131

Strand: Direct

Name: nuoD [H]

Synonym: Bxe_A3211

Alternate gene names: 91782615

Gene position: 1383878-1385131 (Clockwise)

Preceding gene: 91782614

Following gene: 91782616

Centisome position: 28.27

GC content: 59.17

Gene sequence:

>1254_bases
ATGGCAGAGATCAAGAACTACACGCTCAACTTCGGCCCCCAGCACCCGGCAGCGCACGGTGTGCTGCGCCTCGTGCTCGA
ACTCGACGGCGAAGTCATCCAGCGCGCCGATCCGCACATCGGCCTGCTGCATCGCGCGACTGAAAAGCTCGCCGAAACCA
AAACATTCATTCAGTCGGTGCCGTACATGGACCGTCTCGACTACGTGTCGATGATGGTCAATGAGCACGGCTACGTGATG
GCGATCGAAAAGCTGCTCGGCATCGACGTGCCGGTGCGCGCGCAATACATTCGCGTCATGTTCGACGAAATCACGCGCGT
GCTGAACCACCTCATGTGGATCGGCGCGCATGCGCTCGACGTCGGCGCGATGGCGGTGTTCCTTTATGCATTCCGCGAAC
GCGAAGACCTGATGGACGTGTACGAAGCGGTGTCCGGCGCACGGATGCACGCGGCTTACTATCGTCCGGGCGGCGTCTAT
CGCGATCTGCCTGACGCAATGCCGCAATACAAGGCATCGAAAATTCGCAATGCGAAGGCATTGTCGAAGATGAACGAGAA
CCGCCAGGGTTCGCTGCTCGACTTCATCGACGATTTCTTCACGCGTTTCCCGAAGTGTGTCGACGAATACGAAACGCTGC
TCACCGACAACCGGATCTGGAAGCAGCGTCTGGTTGGTATCGGCGTGGTCAGCCCGGAACGCGCGCTGAATCTCGGCATG
ACGGGTGCCATGTTGCGCGGCTCGGGTATCGAGTGGGATCTGCGCAAGAAGCAGCCGTATGAAGTCTATGACAAGCTCGA
TTTCGACATTCCGGTCGGCGTGAATGGCGATTGCTATGACCGCTATCTGGTTCGCGTCGAAGAAATGCGCCAATCCACGC
GCATCGTGAAACAGTGCGTTGAGTGGCTGCGTAAGAATCCAGGCCCCGTGATGATCGACAATCACAAGGTTGCGCCGCCG
TCGCGCGTGGGCATGAAGTCGAACATGGAAGAGCTGATTCACCACTTCAAGCTCTTCACGGAAGGCTTCCATGTTCCGGA
AGGCGAGGCGTATGCGGCTGTCGAGCATCCGAAGGGCGAGTTCGGCATCTACCTGATCTCGGACGGCGCGAACAAGCCGT
ATCGGCTGAAGATCCGCGCACCGGGCTATGCACACCTGTCCACGCTCGACGAAATGGCGCGCGGCCACATGATCGCCGAC
GCCGTGACGATCATCGGCACGCAGGACATCGTGTTCGGCGAAGTGGATCGCTAG

Upstream 100 bases:

>100_bases
GCGCGTCGTCTATCAGCCCGTGACGATCGAGCCGCGGGAAATCACACCGCGCGTGATCCGCGAAGATCGCTATGGCGGTC
TGAAACACTAAGAGAACGCC

Downstream 100 bases:

>100_bases
GACGTATTCATCGGCGCGCGTCTTCAGATTGCACCGAAGCGCGCGGCAAGCAAAGGAACGCCGGGTCTGTCGCAGCATGA
TGTGAGCGACGGGTTTTCGT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETKTFIQSVPYMDRLDYVSMMVNEHGYVM
AIEKLLGIDVPVRAQYIRVMFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDAMPQYKASKIRNAKALSKMNENRQGSLLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALNLGM
TGAMLRGSGIEWDLRKKQPYEVYDKLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIVKQCVEWLRKNPGPVMIDNHKVAPP
SRVGMKSNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLISDGANKPYRLKIRAPGYAHLSTLDEMARGHMIAD
AVTIIGTQDIVFGEVDR

Sequences:

>Translated_417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETKTFIQSVPYMDRLDYVSMMVNEHGYVM
AIEKLLGIDVPVRAQYIRVMFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDAMPQYKASKIRNAKALSKMNENRQGSLLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALNLGM
TGAMLRGSGIEWDLRKKQPYEVYDKLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIVKQCVEWLRKNPGPVMIDNHKVAPP
SRVGMKSNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLISDGANKPYRLKIRAPGYAHLSTLDEMARGHMIAD
AVTIIGTQDIVFGEVDR
>Mature_416_residues
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETKTFIQSVPYMDRLDYVSMMVNEHGYVMA
IEKLLGIDVPVRAQYIRVMFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYR
DLPDAMPQYKASKIRNAKALSKMNENRQGSLLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALNLGMT
GAMLRGSGIEWDLRKKQPYEVYDKLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIVKQCVEWLRKNPGPVMIDNHKVAPPS
RVGMKSNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLISDGANKPYRLKIRAPGYAHLSTLDEMARGHMIADA
VTIIGTQDIVFGEVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=60.6280193236715, Blast_Score=521, Evalue=1e-148,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=59.5588235294118, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=38.780487804878, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1789076, Length=418, Percent_Identity=28.9473684210526, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788832, Length=408, Percent_Identity=27.4509803921569, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17555284, Length=415, Percent_Identity=58.7951807228916, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17568379, Length=415, Percent_Identity=57.5903614457831, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI24638644, Length=415, Percent_Identity=59.7590361445783, Blast_Score=526, Evalue=1e-150,
Organism=Drosophila melanogaster, GI221459469, Length=412, Percent_Identity=54.3689320388349, Blast_Score=468, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47553; Mature: 47421

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETKTFIQSV
CCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMVNEHGYVMAIEKLLGIDVPVRAQYIRVMFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNAKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LSKMNENRQGSLLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALNLGM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHCCC
TGAMLRGSGIEWDLRKKQPYEVYDKLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIVKQCV
CCCEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMIDNHKVAPPSRVGMKSNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLISDGANKPYRLKIRAPGYAHLSTLDEMARGHMIADAVTIIGTQDIVFGEVDR
EEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETKTFIQSV
CCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMVNEHGYVMAIEKLLGIDVPVRAQYIRVMFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNAKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LSKMNENRQGSLLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALNLGM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHCCC
TGAMLRGSGIEWDLRKKQPYEVYDKLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIVKQCV
CCCEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMIDNHKVAPPSRVGMKSNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLISDGANKPYRLKIRAPGYAHLSTLDEMARGHMIADAVTIIGTQDIVFGEVDR
EEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA