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The map label for this gene is mscS [H]

Identifier: 91782557

GI number: 91782557

Start: 1325614

End: 1326534

Strand: Direct

Name: mscS [H]

Synonym: Bxe_A3271

Alternate gene names: 91782557

Gene position: 1325614-1326534 (Clockwise)

Preceding gene: 91782555

Following gene: 91782563

Centisome position: 27.08

GC content: 66.88

Gene sequence:

>921_bases
ATGCTTCAGCAAGCAGTGTGCCTCGCTACGTGGGCGCGTAAAGGGCAGGAAAGGGCAGGAACGCATCCTGCTTCGCTGCA
TCACGACACCGCAACGGAACGAAGACTCAAGATGAACGATCTCCTCGCCCGACTCTTTCACTTCCAGCCGTCGCTGCTCG
TCACGTTGACGCACGACGCCCTTCATATCGTGCTGGCCGTGCTGATCCTCGTGGTCGGCTGGTGGCTGTCGAATCGCGTC
GGCACGATGTTCGCCCGAACGCTCGCGCGCACGCATGCGGACCCGACGCTCGCGCCGATGCTGGCGGCCATGAGCACGTG
GGCCGTGCGCGTGCTGGTTGTCATCGCGGCGCTAGGCGAAGTCGGCATCGCGACCGCGAGCGTGCTGGCGGTGCTCGGTG
CGGCCGGTCTGGCGATTGGACTCGCGTTGCAAGGCACGCTGCAGAACATCGCGGCCGGCATGATGCTGCTGATGCTGCGG
CCGTTTCGCGTCGGCGACGTGATCGAAGGCAGCGGCGCGGCGGCGGGTATCGTGCGCGAAGTGGGGCTCTTCACCACGCG
CATCGAGCGCGGCGACGGCAACGCGGTATTCGTGCCTAACAGCCAGATCTGGAGCAATCCGGTGATCAACTACAGCAGCG
GCGGCACGCAGCGTATCGAGGTCGAAGTGGGCCTCGCGCAGCGCAAGGATGTCGACGCGGCGATCGGCGAATTGAAAAAG
CTCGTCGCCGACGAACCGCGCGTGCTGAGCGGAGCCACGCTCGCACCGATCGTCACGGTGGCGGACTATCCGGACGATGG
CGGCGCGACGCTGCGCATCGCGGCGTGGGTGCGCACGCCGGACGCGTCGCTTGCGAGCGGCGACTTGCACGAGCACGCAC
AGGCCGCGCTCGAACAGGCCGGTTGTCCGGTCGCGGCCTAG

Upstream 100 bases:

>100_bases
CCTTGCGGCGTGTTCCAGCCAACGCGATCTCCGGGCTTCAGAAGTTGGGACATAGGGTACTCGCTCCTATACACGATTCA
GGGCCACCGCTCCCGCGAAC

Downstream 100 bases:

>100_bases
CGCCTCGCTCGCCGCGCATTGCCCGCTCAACGCGCTTGCGGATGGGCGAGGAAGAACCTCACCATTTCCGCGGCCGCATC
GGGTCCGGACGGGTCCGTGT

Product: putative small conductance mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLQQAVCLATWARKGQERAGTHPASLHHDTATERRLKMNDLLARLFHFQPSLLVTLTHDALHIVLAVLILVVGWWLSNRV
GTMFARTLARTHADPTLAPMLAAMSTWAVRVLVVIAALGEVGIATASVLAVLGAAGLAIGLALQGTLQNIAAGMMLLMLR
PFRVGDVIEGSGAAAGIVREVGLFTTRIERGDGNAVFVPNSQIWSNPVINYSSGGTQRIEVEVGLAQRKDVDAAIGELKK
LVADEPRVLSGATLAPIVTVADYPDDGGATLRIAAWVRTPDASLASGDLHEHAQAALEQAGCPVAA

Sequences:

>Translated_306_residues
MLQQAVCLATWARKGQERAGTHPASLHHDTATERRLKMNDLLARLFHFQPSLLVTLTHDALHIVLAVLILVVGWWLSNRV
GTMFARTLARTHADPTLAPMLAAMSTWAVRVLVVIAALGEVGIATASVLAVLGAAGLAIGLALQGTLQNIAAGMMLLMLR
PFRVGDVIEGSGAAAGIVREVGLFTTRIERGDGNAVFVPNSQIWSNPVINYSSGGTQRIEVEVGLAQRKDVDAAIGELKK
LVADEPRVLSGATLAPIVTVADYPDDGGATLRIAAWVRTPDASLASGDLHEHAQAALEQAGCPVAA
>Mature_306_residues
MLQQAVCLATWARKGQERAGTHPASLHHDTATERRLKMNDLLARLFHFQPSLLVTLTHDALHIVLAVLILVVGWWLSNRV
GTMFARTLARTHADPTLAPMLAAMSTWAVRVLVVIAALGEVGIATASVLAVLGAAGLAIGLALQGTLQNIAAGMMLLMLR
PFRVGDVIEGSGAAAGIVREVGLFTTRIERGDGNAVFVPNSQIWSNPVINYSSGGTQRIEVEVGLAQRKDVDAAIGELKK
LVADEPRVLSGATLAPIVTVADYPDDGGATLRIAAWVRTPDASLASGDLHEHAQAALEQAGCPVAA

Specific function: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=195, Percent_Identity=39.4871794871795, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787591, Length=194, Percent_Identity=26.2886597938144, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786670, Length=136, Percent_Identity=26.4705882352941, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014
- InterPro:   IPR008910 [H]

Pfam domain/function: PF00924 MS_channel; PF05552 TM_helix [H]

EC number: NA

Molecular weight: Translated: 32240; Mature: 32240

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQAVCLATWARKGQERAGTHPASLHHDTATERRLKMNDLLARLFHFQPSLLVTLTHDA
CCCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECHHH
LHIVLAVLILVVGWWLSNRVGTMFARTLARTHADPTLAPMLAAMSTWAVRVLVVIAALGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VGIATASVLAVLGAAGLAIGLALQGTLQNIAAGMMLLMLRPFRVGDVIEGSGAAAGIVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
VGLFTTRIERGDGNAVFVPNSQIWSNPVINYSSGGTQRIEVEVGLAQRKDVDAAIGELKK
HHHHHHEEEECCCCEEECCCCHHHCCCCEEECCCCCEEEEEEECCCHHCCHHHHHHHHHH
LVADEPRVLSGATLAPIVTVADYPDDGGATLRIAAWVRTPDASLASGDLHEHAQAALEQA
HHCCCCCEECCCCHHHEEEEECCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHC
GCPVAA
CCCCCC
>Mature Secondary Structure
MLQQAVCLATWARKGQERAGTHPASLHHDTATERRLKMNDLLARLFHFQPSLLVTLTHDA
CCCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECHHH
LHIVLAVLILVVGWWLSNRVGTMFARTLARTHADPTLAPMLAAMSTWAVRVLVVIAALGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VGIATASVLAVLGAAGLAIGLALQGTLQNIAAGMMLLMLRPFRVGDVIEGSGAAAGIVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
VGLFTTRIERGDGNAVFVPNSQIWSNPVINYSSGGTQRIEVEVGLAQRKDVDAAIGELKK
HHHHHHEEEECCCCEEECCCCHHHCCCCEEECCCCCEEEEEEECCCHHCCHHHHHHHHHH
LVADEPRVLSGATLAPIVTVADYPDDGGATLRIAAWVRTPDASLASGDLHEHAQAALEQA
HHCCCCCEECCCCHHHEEEEECCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHC
GCPVAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12542086 [H]