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The map label for this gene is htpG

Identifier: 91782500

GI number: 91782500

Start: 1257511

End: 1259415

Strand: Direct

Name: htpG

Synonym: Bxe_A3329

Alternate gene names: 91782500

Gene position: 1257511-1259415 (Clockwise)

Preceding gene: 91782499

Following gene: 91782502

Centisome position: 25.69

GC content: 60.89

Gene sequence:

>1905_bases
ATGGCACAAGAAACCATGAGCTTTCAGGCAGAAGTGAAACAGCTTCTGCACCTGATGATCCATTCGCTGTACAGCAACAA
GGAGATTTTCCTGCGCGAGCTGATTTCGAACGCGTCCGACGCGGCCGACAAGCTGCGCTTCGAAGCGATCGAAAACAGCG
CGTTGTACGAGAACGATCCGAACCTGCGGATTCGCGTGTCGTACGACAAGGACGCGCGCACCATCACGATCGACGACAAC
GGCATCGGCATGAGCCGCGACGAAGCGATCGCCAACCTCGGCACGATCGCGCGCTCGGGCACCAAGGAATTCTTCGGCAA
GCTCTCCGGCGACCAGCAGAAAGACGCGGCGCTGATCGGCCAGTTCGGTGTGGGCTTCTATTCGGGCTTTATCGTCGCGG
ACAGGATCACCGTGGAAACCCGCCGCGCCGGTTTGCCGGCTTCGGAAGGCGTGCGCTGGGAAAGCGCGGGCGAGGGCGAT
TTCGCGGTCGAGCAGATCGAGCGCGCCGCGCGCGGCACGACCATCACGCTGCATCTGCGTGCGGATGAAGACGAACTGCT
GTCGTCGCATCGTCTGAAATCGATCATTCAGAAGTACTCCGACCACGTCGCGCTGCCGATCCTGATGAAGAAGGAAGAGT
GGGACGCGGAAAAGAGCGCGATGGTCACGAAAGACGAAGACGAGACCGTCAACCAGGCCAGCGCGTTGTGGACGCGTTCG
AAGAGCGACATCACCGACGAGCAGTACAAGCAGTTCTATCAGCACCTCTCGCACGATCATCAGGACCCGCTCACGTGGAC
GCATAACCGTGTCGAAGGCCGCAGCGAGTACACGCAACTGCTGTACGTGCCGACCCACGCGCCGTTCGACATGTTCAACC
GCGATCATCGCGGCGGCCTGAAGCTGTACGTGAAGCGTGTGTTCATCATGGACGACGCCGAGCAACTGCTGCCCGCGTAT
CTGCGTTTCGTGAAGGGCGTGGTCGATTCGGCGGATCTGCCGCTGAACGTGTCGCGCGAAATTCTCCAGGAAAGCCGCGA
CGTGAAGGCGATCCGCGAAGGCGTGACCAAGCGCGTGCTGTCCATGCTCGAAGATCTGGCCAATTCGGATAACGAGGCGG
ACAAGGAAAAGTACGCCGGTTTCTGGAAGGAATTCGGCCAGGTGCTGAAAGAAGGCATTGGCGAAGACTTCGCCAATCGC
GAGCGGATCGCCAAACTCCTGCGCTTTGCGTCGACGCATACGGACACGCCTGAGCAGACCGTGTCGCTCGCCGACTACGT
CGCGCGCATGAAGCCCGAGCAGACCAAGATCTACTACGTCACCGCCGACACCTGGCAGGCCGCGACCCACAGCCCGCACC
TCGAAGTGTTCCGCAAGAAGGGCGTGGAAGTGCTGTTGCTGACCGACCGCGTGGATGAATGGATCCTGTCGTTCCTGACC
GAGTTCGAAGGCAAGCCGCTGCAAAGCGTGGCACGCGGCGATCTCGATCTGGGCGCGCTGAACGACGAAGAAAAAGAGGC
GCAGGAAAAGGTTAGCGAAGAGTTCAAACCGCTCGTCGAGAAGATGAAGGAAGCGCTGAAGGACAAGGCCAAGGACGTGC
GCCTCACGTTCCGCCTGACCGATTCGCCGTCCTGTCTCGTTGCCGACGACGGCGAAATGAGCGGCTATCTGCAACGCATG
CTGAAGGCCGCGGGCCAGCAGGCGCCTTCGTTCCATCCGATTCTCGAGGTGAATCCGGAGCACGCGCTGGTGAAGGGCCT
GCATGCGGACAGCGCGAACTTCGACGACTGGTGCCATTTGCTGTTCGACCAGGCTTTGCTCGCCGAAGGTGGCGCGCTGG
AAGATCCGGCGAGCTTCGTGAAGCGCACCAATGCGCTGCTGCTGGCGCGCGCGAACGAGGCGTGA

Upstream 100 bases:

>100_bases
GCCCGCCGCCGGCTGCCAGGCGACACGCCGGCGGTCAGCCCGCAACGATCGGCGCCGCGCCTGACTTGAACCCCATTCGC
AACAGAGAGGAAGTCCGACC

Downstream 100 bases:

>100_bases
ATCGCACCTGATTTCGCTGCGCCGCGTTGACGCTGCTGATTGAGAAATGCGCTGCTTCGGCAGCGCATTTTTTTGTACGG
CGCGGCGAAGCCGACGCCGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MAQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDPNLRIRVSYDKDARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFGKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGD
FAVEQIERAARGTTITLHLRADEDELLSSHRLKSIIQKYSDHVALPILMKKEEWDAEKSAMVTKDEDETVNQASALWTRS
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPTHAPFDMFNRDHRGGLKLYVKRVFIMDDAEQLLPAY
LRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRVLSMLEDLANSDNEADKEKYAGFWKEFGQVLKEGIGEDFANR
ERIAKLLRFASTHTDTPEQTVSLADYVARMKPEQTKIYYVTADTWQAATHSPHLEVFRKKGVEVLLLTDRVDEWILSFLT
EFEGKPLQSVARGDLDLGALNDEEKEAQEKVSEEFKPLVEKMKEALKDKAKDVRLTFRLTDSPSCLVADDGEMSGYLQRM
LKAAGQQAPSFHPILEVNPEHALVKGLHADSANFDDWCHLLFDQALLAEGGALEDPASFVKRTNALLLARANEA

Sequences:

>Translated_634_residues
MAQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDPNLRIRVSYDKDARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFGKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGD
FAVEQIERAARGTTITLHLRADEDELLSSHRLKSIIQKYSDHVALPILMKKEEWDAEKSAMVTKDEDETVNQASALWTRS
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPTHAPFDMFNRDHRGGLKLYVKRVFIMDDAEQLLPAY
LRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRVLSMLEDLANSDNEADKEKYAGFWKEFGQVLKEGIGEDFANR
ERIAKLLRFASTHTDTPEQTVSLADYVARMKPEQTKIYYVTADTWQAATHSPHLEVFRKKGVEVLLLTDRVDEWILSFLT
EFEGKPLQSVARGDLDLGALNDEEKEAQEKVSEEFKPLVEKMKEALKDKAKDVRLTFRLTDSPSCLVADDGEMSGYLQRM
LKAAGQQAPSFHPILEVNPEHALVKGLHADSANFDDWCHLLFDQALLAEGGALEDPASFVKRTNALLLARANEA
>Mature_633_residues
AQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDPNLRIRVSYDKDARTITIDDNG
IGMSRDEAIANLGTIARSGTKEFFGKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDF
AVEQIERAARGTTITLHLRADEDELLSSHRLKSIIQKYSDHVALPILMKKEEWDAEKSAMVTKDEDETVNQASALWTRSK
SDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPTHAPFDMFNRDHRGGLKLYVKRVFIMDDAEQLLPAYL
RFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRVLSMLEDLANSDNEADKEKYAGFWKEFGQVLKEGIGEDFANRE
RIAKLLRFASTHTDTPEQTVSLADYVARMKPEQTKIYYVTADTWQAATHSPHLEVFRKKGVEVLLLTDRVDEWILSFLTE
FEGKPLQSVARGDLDLGALNDEEKEAQEKVSEEFKPLVEKMKEALKDKAKDVRLTFRLTDSPSCLVADDGEMSGYLQRML
KAAGQQAPSFHPILEVNPEHALVKGLHADSANFDDWCHLLFDQALLAEGGALEDPASFVKRTNALLLARANEA

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI154146191, Length=690, Percent_Identity=37.9710144927536, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI153792590, Length=690, Percent_Identity=37.9710144927536, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI20149594, Length=686, Percent_Identity=37.6093294460641, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI4507677, Length=693, Percent_Identity=36.9408369408369, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=36.4207221350078, Blast_Score=379, Evalue=1e-105,
Organism=Escherichia coli, GI1786679, Length=631, Percent_Identity=61.1727416798732, Blast_Score=789, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=37.890044576523, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=38.0740740740741, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=33.4883720930233, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=432, Percent_Identity=36.1111111111111, Blast_Score=261, Evalue=8e-70,
Organism=Saccharomyces cerevisiae, GI6323840, Length=685, Percent_Identity=39.4160583941606, Blast_Score=468, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6325016, Length=686, Percent_Identity=38.9212827988338, Blast_Score=463, Evalue=1e-131,
Organism=Drosophila melanogaster, GI17647529, Length=686, Percent_Identity=37.6093294460641, Blast_Score=445, Evalue=1e-125,
Organism=Drosophila melanogaster, GI21357739, Length=675, Percent_Identity=37.9259259259259, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24586016, Length=649, Percent_Identity=35.4391371340524, Blast_Score=371, Evalue=1e-102,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_BURXL (Q142T5)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_557706.1
- ProteinModelPortal:   Q142T5
- SMR:   Q142T5
- GeneID:   4002112
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A3329
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71623; Mature: 71492

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDP
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
NLRIRVSYDKDARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFGKLSGDQQKDAALIG
CEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHH
QFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFAVEQIERAARGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEE
ADEDELLSSHRLKSIIQKYSDHVALPILMKKEEWDAEKSAMVTKDEDETVNQASALWTRS
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHCC
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPTHAPFDMFNRDHRGGL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPAYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRVL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEDLANSDNEADKEKYAGFWKEFGQVLKEGIGEDFANRERIAKLLRFASTHTDTPEQT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHH
VSLADYVARMKPEQTKIYYVTADTWQAATHSPHLEVFRKKGVEVLLLTDRVDEWILSFLT
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHH
EFEGKPLQSVARGDLDLGALNDEEKEAQEKVSEEFKPLVEKMKEALKDKAKDVRLTFRLT
HHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DSPSCLVADDGEMSGYLQRMLKAAGQQAPSFHPILEVNPEHALVKGLHADSANFDDWCHL
CCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHH
LFDQALLAEGGALEDPASFVKRTNALLLARANEA
HHHHHHHHCCCCCCCHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure 
AQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDP
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
NLRIRVSYDKDARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFGKLSGDQQKDAALIG
CEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHH
QFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFAVEQIERAARGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEE
ADEDELLSSHRLKSIIQKYSDHVALPILMKKEEWDAEKSAMVTKDEDETVNQASALWTRS
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHCC
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPTHAPFDMFNRDHRGGL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPAYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRVL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEDLANSDNEADKEKYAGFWKEFGQVLKEGIGEDFANRERIAKLLRFASTHTDTPEQT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHH
VSLADYVARMKPEQTKIYYVTADTWQAATHSPHLEVFRKKGVEVLLLTDRVDEWILSFLT
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHH
EFEGKPLQSVARGDLDLGALNDEEKEAQEKVSEEFKPLVEKMKEALKDKAKDVRLTFRLT
HHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DSPSCLVADDGEMSGYLQRMLKAAGQQAPSFHPILEVNPEHALVKGLHADSANFDDWCHL
CCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHH
LFDQALLAEGGALEDPASFVKRTNALLLARANEA
HHHHHHHHCCCCCCCHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA