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The map label for this gene is lip2 [H]

Identifier: 91782229

GI number: 91782229

Start: 948645

End: 949598

Strand: Direct

Name: lip2 [H]

Synonym: Bxe_A3606

Alternate gene names: 91782229

Gene position: 948645-949598 (Clockwise)

Preceding gene: 91782228

Following gene: 91782230

Centisome position: 19.38

GC content: 61.43

Gene sequence:

>954_bases
ATGGAACCCGAGCTGAAGGCGTTGATAGAACAACTAAGCCAGGCAGGGCGGCGGCCGTTCTGGCAGTGCACTGTCGACGA
CGCGCGCAATGCGCCGACACTGGTTAAGCGTCTCTTTCCCGATGCGCCGTCTGTCGAACGGACGCAGGACATCCGCATTT
CTTCCACGCGCGGTCATGCATTTCCGGCACGGCTCTACGTGCCGCGTGACAGGCCATGCGGCCTGATTGTCTATCTGCAT
GGCGGCGGCTGGGTCGTCGGTTCTGTCGACGACTATCATCCGCTCACTGCCACGATCACGGCGAGGAGCGGATTTGCCGT
GTTATCGGTGGACTATCGTCTTGCTCCGGAGCACGCGTTTCCCATTCCGCTGGAAGACGCGCGTGCCGCGTTGGAATGGG
CGTCGTCAGGCTCCGCCGCGGTGGCAATTGGTGCGGACGTGAATTGTCTAATCGTGATGGGCGACAGCGCGGGAGCGAAT
CTGGCCACCGTCGCTGCGCGCCTGCATAACGAAAAAAATATTGATCGGCGCGTGGACGGGCAGGTGCTCGTGTATCCGGT
TACAGGACATGATTTCAAAACCGCCAGCTACGACGAGTTCGCCGAAGGCAATCTGCTTACGCGAAACGACATGCAGTGGT
TCTGGGATCACTACTGTCCCGAACGGGCGGCGCGCGCGAATCCTCTCGCTTCACCGCTCGAAGCGGAAGATCTGAGCATG
TCGCCGCCCGCGCTCGTCATGACGGCCGGACGCGATCCGCTACGCGACGAAGGGGAAGCTTATGGCGCACGTCTTCGGAA
GGCGGGTGTCGATGTTGCAGTCGTCCGATGTGACGGGCTTGTGCACGGCTTTCTCGCGATGATCCACCAGGTCCCCGGCG
CCGCAAGGGCGTTCGACAGGATCGTCGATTACATCACCCGGTTAGGCGAAGCAGTACCAGAGGCTCGACGCTAG

Upstream 100 bases:

>100_bases
TGGATATGCCGGTAGCCGAGGTCAGCGTGCTGGCGCGCAGCAGCGAGCAGGCGCCCTGACACCGCAAAACGGAAACGGCG
TCTCGCTGAAAAGGATGCGA

Downstream 100 bases:

>100_bases
CGCACACCTCGCATCTGCGGCATCTCCGGCGCGCATAGTCGCGCCTTTCTCCGTTTTCCACTCCCAGAAAAGCGACCAGT
GCGACCGGGCAAGACCAGCG

Product: putative esterase/lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEPELKALIEQLSQAGRRPFWQCTVDDARNAPTLVKRLFPDAPSVERTQDIRISSTRGHAFPARLYVPRDRPCGLIVYLH
GGGWVVGSVDDYHPLTATITARSGFAVLSVDYRLAPEHAFPIPLEDARAALEWASSGSAAVAIGADVNCLIVMGDSAGAN
LATVAARLHNEKNIDRRVDGQVLVYPVTGHDFKTASYDEFAEGNLLTRNDMQWFWDHYCPERAARANPLASPLEAEDLSM
SPPALVMTAGRDPLRDEGEAYGARLRKAGVDVAVVRCDGLVHGFLAMIHQVPGAARAFDRIVDYITRLGEAVPEARR

Sequences:

>Translated_317_residues
MEPELKALIEQLSQAGRRPFWQCTVDDARNAPTLVKRLFPDAPSVERTQDIRISSTRGHAFPARLYVPRDRPCGLIVYLH
GGGWVVGSVDDYHPLTATITARSGFAVLSVDYRLAPEHAFPIPLEDARAALEWASSGSAAVAIGADVNCLIVMGDSAGAN
LATVAARLHNEKNIDRRVDGQVLVYPVTGHDFKTASYDEFAEGNLLTRNDMQWFWDHYCPERAARANPLASPLEAEDLSM
SPPALVMTAGRDPLRDEGEAYGARLRKAGVDVAVVRCDGLVHGFLAMIHQVPGAARAFDRIVDYITRLGEAVPEARR
>Mature_317_residues
MEPELKALIEQLSQAGRRPFWQCTVDDARNAPTLVKRLFPDAPSVERTQDIRISSTRGHAFPARLYVPRDRPCGLIVYLH
GGGWVVGSVDDYHPLTATITARSGFAVLSVDYRLAPEHAFPIPLEDARAALEWASSGSAAVAIGADVNCLIVMGDSAGAN
LATVAARLHNEKNIDRRVDGQVLVYPVTGHDFKTASYDEFAEGNLLTRNDMQWFWDHYCPERAARANPLASPLEAEDLSM
SPPALVMTAGRDPLRDEGEAYGARLRKAGVDVAVVRCDGLVHGFLAMIHQVPGAARAFDRIVDYITRLGEAVPEARR

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68299767, Length=327, Percent_Identity=27.5229357798165, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI206597554, Length=299, Percent_Identity=27.7591973244147, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI157041239, Length=334, Percent_Identity=25.4491017964072, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI68051721, Length=147, Percent_Identity=29.2517006802721, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI61966717, Length=336, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786682, Length=263, Percent_Identity=26.615969581749, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17567059, Length=270, Percent_Identity=29.6296296296296, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71996133, Length=143, Percent_Identity=35.6643356643357, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540028, Length=143, Percent_Identity=35.6643356643357, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI72001146, Length=154, Percent_Identity=34.4155844155844, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533410, Length=112, Percent_Identity=37.5, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533412, Length=112, Percent_Identity=37.5, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 34667; Mature: 34667

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPELKALIEQLSQAGRRPFWQCTVDDARNAPTLVKRLFPDAPSVERTQDIRISSTRGHA
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCC
FPARLYVPRDRPCGLIVYLHGGGWVVGSVDDYHPLTATITARSGFAVLSVDYRLAPEHAF
CEEEEECCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEECCCEEEEEEEEEECCCCCC
PIPLEDARAALEWASSGSAAVAIGADVNCLIVMGDSAGANLATVAARLHNEKNIDRRVDG
CCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCC
QVLVYPVTGHDFKTASYDEFAEGNLLTRNDMQWFWDHYCPERAARANPLASPLEAEDLSM
CEEEEEECCCCCCCCCCCHHCCCCEEECCCHHHHHHHHCHHHHHCCCCCCCCCCCCCCCC
SPPALVMTAGRDPLRDEGEAYGARLRKAGVDVAVVRCDGLVHGFLAMIHQVPGAARAFDR
CCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHH
IVDYITRLGEAVPEARR
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEPELKALIEQLSQAGRRPFWQCTVDDARNAPTLVKRLFPDAPSVERTQDIRISSTRGHA
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCC
FPARLYVPRDRPCGLIVYLHGGGWVVGSVDDYHPLTATITARSGFAVLSVDYRLAPEHAF
CEEEEECCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEECCCEEEEEEEEEECCCCCC
PIPLEDARAALEWASSGSAAVAIGADVNCLIVMGDSAGANLATVAARLHNEKNIDRRVDG
CCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCC
QVLVYPVTGHDFKTASYDEFAEGNLLTRNDMQWFWDHYCPERAARANPLASPLEAEDLSM
CEEEEEECCCCCCCCCCCHHCCCCEEECCCHHHHHHHHCHHHHHCCCCCCCCCCCCCCCC
SPPALVMTAGRDPLRDEGEAYGARLRKAGVDVAVVRCDGLVHGFLAMIHQVPGAARAFDR
CCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHH
IVDYITRLGEAVPEARR
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]