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The map label for this gene is ttuB [H]

Identifier: 91782223

GI number: 91782223

Start: 942942

End: 944288

Strand: Direct

Name: ttuB [H]

Synonym: Bxe_A3612

Alternate gene names: 91782223

Gene position: 942942-944288 (Clockwise)

Preceding gene: 91782221

Following gene: 91782224

Centisome position: 19.26

GC content: 59.32

Gene sequence:

>1347_bases
ATGAATGGGATCGACGGCGGGGCACCTGACCAGGTACTGGAACGCCGCATATTGCGAAAAGTCGGATGGCGTATCTTGCC
GATTCTGCTGCTGGGGTTTTTAATCTCATTCATCGACCGGGCAAACGTCGGCGTGCTCTACGGACCGCTCACACATTCGC
TCGGTCTGACCGCATCGAGCTTTGGTCTCGCCGCAGGACTTTTCTACATCGGTTATCTGGTCTTCGAGATTCCGTCGAAC
CTCGCGATGGCGAAATATGGTGCTCGCGTGTGGCTCGCGCGTATCCTAGTTACGTGGGGGTTCGTTACGGTCGCGCTTGC
GGCCGCACAGGGCGTCACGTCGTTTTATATCCTTCGCATCCTGCTCGGCGTCGCCGAGGCGGGGTTCTATCCCGGCGCGC
TGTTTTTCCTGACGCTCTGGTATCCGCCGCGCGCGCTCGGCCGTGCCTATTCTCTTTTCGAAATAAGTATCCCGGCATCG
CTTGCGATCGGGTCACTGCTGACGTCGAGTTTGCTGCTGCTCGACGGCGTCTGGGGCATCGCAGGGTGGAAATGGGTGTT
CATCCTCGAAGGGCTGCCGGCAATCGCGCTTGGTCTCTACATATTTTTCGTGCTGCCGGATAATCCCGACAAAGCAACAT
GGCTCACTGCAGAAGAAACGTGCTATCTGAATTCGCAGCTCCTAACGCGGCATGAAAGCGCGAAATCCGAGCTGGGCAAG
GTCGCCGTCATTTTCCAGAGCGGGCTCGCGTGGATCTTTGCGGCGCTCTACTTCTCCTTCGTGATCGGATTCTGGGCCGT
CACATATTTTCTGCCGAAGATCGTTCAGGAACGCTTTCACGTTGGTGTCGTGCAGGCCGGCGCCATCTCGGCGATTCCGT
GGATCGTCGCAGTGCTCGCCATCATCGTCGTTTCGCGCACTTCTGCGAAAACGCGCGACCGTCGCTGGCACATGCTCGTT
CTGCTCGGCCTGGCCGGTATCGGTCTGTTGATGAGCGCAGCGGTCGCTTCACCCATTCTCGCGCTGATCGGCATTGCGAT
GGGTGCCGCTGGCATGCAGGCCGCGACGCCGCTCTTCTGGACGATGCCTTCCACCGTGTTCCGCGGTGCGATGGCCGCCG
TCGCACTCGCCATGGTCAATTCGCTCGGCAATCTGAGCGGCCTCGCGGGACCGTGGATTCTCGGTTTCTTTAGCGATGTG
ACGGGCAGTAGCCGCGTCGGTCTTTACATCATGTCGGGCTTTTTCTTCGTGTCTGCCATTCTCGCTTTCGCGGTTAGCAC
CGCGGTGACGAGGCGCCGCGACGTGATCGGATCGCCGTCGCTCGAACAACCTATCGGAAGTTACTGA

Upstream 100 bases:

>100_bases
GACGCATGCAGGAATCGATAGGCTGCCTTGTGGGTGTCGAGATCGGCGGGCTCAGGGAGACAGAGCTCGTTAAGAAAATA
ATCTGTGAGGTACGACAATC

Downstream 100 bases:

>100_bases
CATCCTGTGCCGCGCATGCGGCTCGCAATCATGGAGAACAACGCATGGCTATCGTCGAGGAGCGCTGTTACGTACTGCAT
TCGCAATTTGGACCGGCGGA

Product: major facilitator superfamily metabolite/H(+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNGIDGGAPDQVLERRILRKVGWRILPILLLGFLISFIDRANVGVLYGPLTHSLGLTASSFGLAAGLFYIGYLVFEIPSN
LAMAKYGARVWLARILVTWGFVTVALAAAQGVTSFYILRILLGVAEAGFYPGALFFLTLWYPPRALGRAYSLFEISIPAS
LAIGSLLTSSLLLLDGVWGIAGWKWVFILEGLPAIALGLYIFFVLPDNPDKATWLTAEETCYLNSQLLTRHESAKSELGK
VAVIFQSGLAWIFAALYFSFVIGFWAVTYFLPKIVQERFHVGVVQAGAISAIPWIVAVLAIIVVSRTSAKTRDRRWHMLV
LLGLAGIGLLMSAAVASPILALIGIAMGAAGMQAATPLFWTMPSTVFRGAMAAVALAMVNSLGNLSGLAGPWILGFFSDV
TGSSRVGLYIMSGFFFVSAILAFAVSTAVTRRRDVIGSPSLEQPIGSY

Sequences:

>Translated_448_residues
MNGIDGGAPDQVLERRILRKVGWRILPILLLGFLISFIDRANVGVLYGPLTHSLGLTASSFGLAAGLFYIGYLVFEIPSN
LAMAKYGARVWLARILVTWGFVTVALAAAQGVTSFYILRILLGVAEAGFYPGALFFLTLWYPPRALGRAYSLFEISIPAS
LAIGSLLTSSLLLLDGVWGIAGWKWVFILEGLPAIALGLYIFFVLPDNPDKATWLTAEETCYLNSQLLTRHESAKSELGK
VAVIFQSGLAWIFAALYFSFVIGFWAVTYFLPKIVQERFHVGVVQAGAISAIPWIVAVLAIIVVSRTSAKTRDRRWHMLV
LLGLAGIGLLMSAAVASPILALIGIAMGAAGMQAATPLFWTMPSTVFRGAMAAVALAMVNSLGNLSGLAGPWILGFFSDV
TGSSRVGLYIMSGFFFVSAILAFAVSTAVTRRRDVIGSPSLEQPIGSY
>Mature_448_residues
MNGIDGGAPDQVLERRILRKVGWRILPILLLGFLISFIDRANVGVLYGPLTHSLGLTASSFGLAAGLFYIGYLVFEIPSN
LAMAKYGARVWLARILVTWGFVTVALAAAQGVTSFYILRILLGVAEAGFYPGALFFLTLWYPPRALGRAYSLFEISIPAS
LAIGSLLTSSLLLLDGVWGIAGWKWVFILEGLPAIALGLYIFFVLPDNPDKATWLTAEETCYLNSQLLTRHESAKSELGK
VAVIFQSGLAWIFAALYFSFVIGFWAVTYFLPKIVQERFHVGVVQAGAISAIPWIVAVLAIIVVSRTSAKTRDRRWHMLV
LLGLAGIGLLMSAAVASPILALIGIAMGAAGMQAATPLFWTMPSTVFRGAMAAVALAMVNSLGNLSGLAGPWILGFFSDV
TGSSRVGLYIMSGFFFVSAILAFAVSTAVTRRRDVIGSPSLEQPIGSY

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=376, Percent_Identity=32.9787234042553, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI2367379, Length=427, Percent_Identity=21.0772833723653, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789515, Length=418, Percent_Identity=23.2057416267943, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=438, Percent_Identity=21.689497716895, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322025, Length=224, Percent_Identity=25, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=275, Percent_Identity=22.1818181818182, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=266, Percent_Identity=25.5639097744361, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321502, Length=221, Percent_Identity=24.8868778280543, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=209, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=232, Percent_Identity=22.8448275862069, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324410, Length=152, Percent_Identity=23.6842105263158, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28573299, Length=298, Percent_Identity=24.1610738255034, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48158; Mature: 48158

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIDGGAPDQVLERRILRKVGWRILPILLLGFLISFIDRANVGVLYGPLTHSLGLTASS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCHHH
FGLAAGLFYIGYLVFEIPSNLAMAKYGARVWLARILVTWGFVTVALAAAQGVTSFYILRI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGVAEAGFYPGALFFLTLWYPPRALGRAYSLFEISIPASLAIGSLLTSSLLLLDGVWGI
HHHHHHCCCCCHHHHHHHHCCCHHHHCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AGWKWVFILEGLPAIALGLYIFFVLPDNPDKATWLTAEETCYLNSQLLTRHESAKSELGK
CCHHHHHHHCCHHHHHHHHHHEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
VAVIFQSGLAWIFAALYFSFVIGFWAVTYFLPKIVQERFHVGVVQAGAISAIPWIVAVLA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
IIVVSRTSAKTRDRRWHMLVLLGLAGIGLLMSAAVASPILALIGIAMGAAGMQAATPLFW
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHC
TMPSTVFRGAMAAVALAMVNSLGNLSGLAGPWILGFFSDVTGSSRVGLYIMSGFFFVSAI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LAFAVSTAVTRRRDVIGSPSLEQPIGSY
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGIDGGAPDQVLERRILRKVGWRILPILLLGFLISFIDRANVGVLYGPLTHSLGLTASS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCHHH
FGLAAGLFYIGYLVFEIPSNLAMAKYGARVWLARILVTWGFVTVALAAAQGVTSFYILRI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGVAEAGFYPGALFFLTLWYPPRALGRAYSLFEISIPASLAIGSLLTSSLLLLDGVWGI
HHHHHHCCCCCHHHHHHHHCCCHHHHCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AGWKWVFILEGLPAIALGLYIFFVLPDNPDKATWLTAEETCYLNSQLLTRHESAKSELGK
CCHHHHHHHCCHHHHHHHHHHEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
VAVIFQSGLAWIFAALYFSFVIGFWAVTYFLPKIVQERFHVGVVQAGAISAIPWIVAVLA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
IIVVSRTSAKTRDRRWHMLVLLGLAGIGLLMSAAVASPILALIGIAMGAAGMQAATPLFW
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHC
TMPSTVFRGAMAAVALAMVNSLGNLSGLAGPWILGFFSDVTGSSRVGLYIMSGFFFVSAI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LAFAVSTAVTRRRDVIGSPSLEQPIGSY
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]