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The map label for this gene is rmlA1 [H]

Identifier: 91782109

GI number: 91782109

Start: 821069

End: 821962

Strand: Direct

Name: rmlA1 [H]

Synonym: Bxe_A3726

Alternate gene names: 91782109

Gene position: 821069-821962 (Clockwise)

Preceding gene: 91782108

Following gene: 91782110

Centisome position: 16.77

GC content: 60.18

Gene sequence:

>894_bases
ATGGCGCGTAAAGGCATTATTCTCGCGGGCGGCTCGGGCACGCGCCTGTATCCGATCACGCACGTCGTCTCCAAGCAGTT
GCTGCCGGTGTACGACAAACCGATGATCTACTACCCGCTGTCCACGCTGATGGTGGCGGGCATCCGCGACGTACTGATCA
TTTCGACGCCGCAGGACACGCCGCGCTTCGAGGCGATGCTCGGCGACGGCAGCCAGTGGGGGATGAACATCCGGTATGCG
GTGCAGCCTTCGCCGGACGGTCTCGCGCAGGCATTTATTATCGGTCGCGACTTTGTGGGCAACGATCCGTCGGCGCTGAT
TCTGGGCGACAACATCTTCTACGGTCACGATCTGGCGAAGCAGCTGGAAAACGCCGACGGGAAAACGGAAGGCGCGACCG
TCTTTGCGTACCACGTGCAGGACCCGGAACGGTATGGCGTGGTGGAATTCGACCGGCAGTTCCGCGCGCTGTCGATCGAG
GAGAAGCCCGTGAAGCCGCGTTCGAACTACGCGGTCACGGGTCTGTACTTCTACGACAACCAGGTCTGCGATATCGCCGC
CGACATCAAGCCGTCGCCGCGTGGCGAGCTCGAAATCACCGACGTCAACTCGCGGTATCTCGCCAATGCGGCGCTCAATG
TCGAGATCATGGGGCGCGGTTATGCCTGGCTCGATACCGGCACGCATGATTCGCTGATCGAGGCGGCGACGTTCATCGAA
ACACTGCAGAAACGTCAAGGTCTGGTGGTGGCGTGTCCGGAAGAGATTGCGTTCCGCCAACAGTGGATCGATGAGGAGAG
GTTGCTTCAACTTGCGAAGCCACTTTCCAAGAATGCGTATGGCCAATATCTGCTCAATCTTCCGCAAGATCAGGTGGCAT
GGCCGGCCCGTTGA

Upstream 100 bases:

>100_bases
TGGTATCTGGACAATCAGGCGTGGTCGAACGAAGTCGCCTCGGGCGAGTACCGCAAGTGGGTTGAGACCAACTACGCGCA
GCGCGCGTAAGGGCAAGGCA

Downstream 100 bases:

>100_bases
TCCGGGTGATCGAATGGGGCAAGCGTTTGCGCTGTCCTTGCAATAGCCGATACGTAACTTGCGGAACGTGCGCCGGCGCA
CATTTAATTTGAAACTGCGC

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: G1P-TT 1; dTDP-glucose pyrophosphorylase 1; dTDP-glucose synthase 1 [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDTPRFEAMLGDGSQWGMNIRYA
VQPSPDGLAQAFIIGRDFVGNDPSALILGDNIFYGHDLAKQLENADGKTEGATVFAYHVQDPERYGVVEFDRQFRALSIE
EKPVKPRSNYAVTGLYFYDNQVCDIAADIKPSPRGELEITDVNSRYLANAALNVEIMGRGYAWLDTGTHDSLIEAATFIE
TLQKRQGLVVACPEEIAFRQQWIDEERLLQLAKPLSKNAYGQYLLNLPQDQVAWPAR

Sequences:

>Translated_297_residues
MARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDTPRFEAMLGDGSQWGMNIRYA
VQPSPDGLAQAFIIGRDFVGNDPSALILGDNIFYGHDLAKQLENADGKTEGATVFAYHVQDPERYGVVEFDRQFRALSIE
EKPVKPRSNYAVTGLYFYDNQVCDIAADIKPSPRGELEITDVNSRYLANAALNVEIMGRGYAWLDTGTHDSLIEAATFIE
TLQKRQGLVVACPEEIAFRQQWIDEERLLQLAKPLSKNAYGQYLLNLPQDQVAWPAR
>Mature_296_residues
ARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDTPRFEAMLGDGSQWGMNIRYAV
QPSPDGLAQAFIIGRDFVGNDPSALILGDNIFYGHDLAKQLENADGKTEGATVFAYHVQDPERYGVVEFDRQFRALSIEE
KPVKPRSNYAVTGLYFYDNQVCDIAADIKPSPRGELEITDVNSRYLANAALNVEIMGRGYAWLDTGTHDSLIEAATFIET
LQKRQGLVVACPEEIAFRQQWIDEERLLQLAKPLSKNAYGQYLLNLPQDQVAWPAR

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788351, Length=288, Percent_Identity=71.875, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1790224, Length=284, Percent_Identity=64.0845070422535, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1787488, Length=237, Percent_Identity=27.4261603375527, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=182, Percent_Identity=24.7252747252747, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355443, Length=247, Percent_Identity=21.8623481781377, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644084, Length=247, Percent_Identity=21.8623481781377, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 33129; Mature: 32998

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDT
CCCCCEEEECCCCCEEEEHHHHHHHHCCCCCCCCEEEECHHHHHHHCCCEEEEEECCCCC
PRFEAMLGDGSQWGMNIRYAVQPSPDGLAQAFIIGRDFVGNDPSALILGDNIFYGHDLAK
CCEEEEECCCCCCCEEEEEEECCCCCHHHEEEEEECCCCCCCCCEEEEECCEEECHHHHH
QLENADGKTEGATVFAYHVQDPERYGVVEFDRQFRALSIEEKPVKPRSNYAVTGLYFYDN
HHHCCCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEEECC
QVCDIAADIKPSPRGELEITDVNSRYLANAALNVEIMGRGYAWLDTGTHDSLIEAATFIE
CEEEEEECCCCCCCCCEEEEECCCEEEEEEEEEEEEEECCEEEEECCCCHHHHHHHHHHH
TLQKRQGLVVACPEEIAFRQQWIDEERLLQLAKPLSKNAYGQYLLNLPQDQVAWPAR
HHHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHEEECCHHHCCCCCC
>Mature Secondary Structure 
ARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDT
CCCCEEEECCCCCEEEEHHHHHHHHCCCCCCCCEEEECHHHHHHHCCCEEEEEECCCCC
PRFEAMLGDGSQWGMNIRYAVQPSPDGLAQAFIIGRDFVGNDPSALILGDNIFYGHDLAK
CCEEEEECCCCCCCEEEEEEECCCCCHHHEEEEEECCCCCCCCCEEEEECCEEECHHHHH
QLENADGKTEGATVFAYHVQDPERYGVVEFDRQFRALSIEEKPVKPRSNYAVTGLYFYDN
HHHCCCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEEECC
QVCDIAADIKPSPRGELEITDVNSRYLANAALNVEIMGRGYAWLDTGTHDSLIEAATFIE
CEEEEEECCCCCCCCCEEEEECCCEEEEEEEEEEEEEECCEEEEECCCCHHHHHHHHHHH
TLQKRQGLVVACPEEIAFRQQWIDEERLLQLAKPLSKNAYGQYLLNLPQDQVAWPAR
HHHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHEEECCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7517391; 9097040; 9278503; 7517390 [H]