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The map label for this gene is epsB [H]

Identifier: 91781980

GI number: 91781980

Start: 671672

End: 673906

Strand: Direct

Name: epsB [H]

Synonym: Bxe_A3864

Alternate gene names: 91781980

Gene position: 671672-673906 (Clockwise)

Preceding gene: 91781979

Following gene: 91781981

Centisome position: 13.72

GC content: 64.07

Gene sequence:

>2235_bases
ATGGCAATCAACTTCGAAAACCGCTACACCGACGTGTCCGGACCGGACGAGCTTCACCTGTCGGACTATCTGCGTACGAT
CGTGCGGGGTTGGCGCACGATCGCGATGGTGACGCTGATCGCGCTCGCGCTGGGGTGCGCGTACGCCTTCCTCGCGCCGC
CGACTTACCGCGCGGATGTTCTGTTTCACGTCGAGGACAAGACGGCGAATGCCAATGCGAACGGCAAGGATTCCTTGCCG
CCGCTCACCGGCATGTTCGACACCAAGCCTTCCACGGCAGCCGAGATCGAGTTGCTGAAGTCGCGGCTCGTCACGGAAGA
AACCGTCAAGAAGCTGCACCTCGATATCTCGGCGGCGCCGCGTTATTTTCCGGTCATTGGCGGAATGATCGCGGGGTTGG
TGAACGGGCAATGGGGCTTCAGGTTGCCGCAGTTCATCAACCTGTCCGGCTATGCATGGGGTGACGAGGCCATTACGGTG
TCGCAGTTCGACACGTCGAAAGACATGTACGACACCACCTTCACGCTGATTGCCGGCAATGACGGTTCATACGTGTTGCG
CGACAGGAATGGTATCGCGATCCTGTCGGGCAAAGTGGGCGAGACCGTGGAAACGGATACCGCCGACGGACCGATCACGT
TGCACGTCGACAAGCTGGTCGGCCCGGCCGGCTCGCGCTTCGAATTGTCGCGCGCGTCGACGCTGAGCACCGTGGACCGG
CTGCAAAAGGCCCTGGTGGTGCAGGAAACCACGCTGCAATCCGGCGTGATCCGCGCGAGTCTGGAAGGCGGCGACAGCGC
GCTGACCGCGGCGATCGTCAACAGCATGGCGCGCGAGTTCGTGCGCCAGGATGTCGAGAGCCGTTCGACCGAAGCCGAGC
ATATGCTGGCCTTTCTCGATCAGCAACTGCCGGGCTTGCGCAAGGAACTCGACGACGCCGAGCAACGCTACAACAAGTTC
CGCAACACGCACGGCACCGTCGACCTCGGTGAAGAAAGCCGCTTGCTGCTGCAACAGATCGTCGATAACAAGACCAAGCT
GATGGATCTGCAGCAGCAGCGCGCGGAGATGTCGCAACGCTTCACCGCGAATCACCCGGCGGTGGCCGCGCTCGACGCGC
AGATCGCCGCGTTGCAAGGCGCGGCGGCCAATATGAACCGCAGCGTGGCGGTCATGCCGGATACGGAGCAGACCGCACTG
CGCTTGCTGCGCGACGTGCATGTCGACACCGAGCTGTACACCAATCTGCTGAACAGCGCGCAGCAACTGCGCGTGGCGAA
GGCGGGGCAGGTGGGCAGCGTGCGCGTGGTCGACTTCGCGGAAGCGCCGGACGACCCCGTGCGTCCGAAGCGCGTGATCG
CGATCCTGATCGCGCTCGGCGGCGGACTCGTGCTCGGCATTCTGCTGACCTTCTTCAAGCGCGCCATGTACGGCGGCGTG
GAACGTCCGGACGAACTCGAAGGCATGCTCGGCGTGCCGGTGTTCGCGGTGGTGCCGCGCAGCCAGACCCAGCTGAAGCT
GCAGGAAAACGTCATGCTGCGCCGTCGCGGGCTGCATGTGCTGGCGCAGCAGGCGCCGGAAGACATCGCCGTGGAAGGCG
TGCGCAATCTGCGCACCTCGCTGCAGCTCTCGCTCGATCACGCCGAGAACAACGTGGTGATGATCACCGGCTCGCGGCCC
GATTCCGGCAAGTCGTTCCTCTCGGTGAATCTGGCGGCGCTGGTGGCGTCGGCCAATAAGCGGGTGCTGATCATCGACGG
TGATATGCGGCGCGGCGACGTGCACTCGCATTTCGGTATCGGTCATCAGCCGGGCCTGTCCGACGTGCTGAGCGGCGGCG
ACCTGAACGCGATGATCCAGCGCGACGTGCTGCCGGGTCTCGATGTGCTCGCCAAGGGCACGCTGCCTTCGCATCCGGCC
GAACTGCTGATGAGCAAGCGCTTCGAAACGATGCTCGAAGAATTGAAGTCGCACTACGACCTCGTGATCGTCGATACGCC
GCCGGTTCTGGCGGTGACCGATTCGACGCTGATCGGCAAATACGCGGGCACGACGCTGCTGGTGGTGCGCCACGGCCGCC
ATCCGCTCAACGAGGTGATGGAAACGGCCAAGCGGCTGCGCAACGGCGGCGTGGCGCTGCGGGGCGTGCTGCTGACCGAC
GTGCCGCAGGAAGGCGCGTTCCTCGGCTCGGGTTATCAAGGCGGTTACTACGGCTACGACAGCATCGCCGGTTGA

Upstream 100 bases:

>100_bases
TGCTGCCGGCGATCAATGCGGCTGTAACGGGCGCCGTCCTCGCGAAATAACAACCGTGCAAACGTGATCTTGAACCGCCG
GGCTTTGTTGGGTGAAGAAA

Downstream 100 bases:

>100_bases
CATGGCGGCGGATAGCTGATGGTCAGACGAGGTTCAACGAGGTTGCGGCATCAGGCTTGCAAAGGTTAACGAGGAGAATG
CTCCATGAAACGTAAGGTCG

Product: exopolysaccharide export associated tyrosine kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: EPS I polysaccharide export protein epsB [H]

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MAINFENRYTDVSGPDELHLSDYLRTIVRGWRTIAMVTLIALALGCAYAFLAPPTYRADVLFHVEDKTANANANGKDSLP
PLTGMFDTKPSTAAEIELLKSRLVTEETVKKLHLDISAAPRYFPVIGGMIAGLVNGQWGFRLPQFINLSGYAWGDEAITV
SQFDTSKDMYDTTFTLIAGNDGSYVLRDRNGIAILSGKVGETVETDTADGPITLHVDKLVGPAGSRFELSRASTLSTVDR
LQKALVVQETTLQSGVIRASLEGGDSALTAAIVNSMAREFVRQDVESRSTEAEHMLAFLDQQLPGLRKELDDAEQRYNKF
RNTHGTVDLGEESRLLLQQIVDNKTKLMDLQQQRAEMSQRFTANHPAVAALDAQIAALQGAAANMNRSVAVMPDTEQTAL
RLLRDVHVDTELYTNLLNSAQQLRVAKAGQVGSVRVVDFAEAPDDPVRPKRVIAILIALGGGLVLGILLTFFKRAMYGGV
ERPDELEGMLGVPVFAVVPRSQTQLKLQENVMLRRRGLHVLAQQAPEDIAVEGVRNLRTSLQLSLDHAENNVVMITGSRP
DSGKSFLSVNLAALVASANKRVLIIDGDMRRGDVHSHFGIGHQPGLSDVLSGGDLNAMIQRDVLPGLDVLAKGTLPSHPA
ELLMSKRFETMLEELKSHYDLVIVDTPPVLAVTDSTLIGKYAGTTLLVVRHGRHPLNEVMETAKRLRNGGVALRGVLLTD
VPQEGAFLGSGYQGGYYGYDSIAG

Sequences:

>Translated_744_residues
MAINFENRYTDVSGPDELHLSDYLRTIVRGWRTIAMVTLIALALGCAYAFLAPPTYRADVLFHVEDKTANANANGKDSLP
PLTGMFDTKPSTAAEIELLKSRLVTEETVKKLHLDISAAPRYFPVIGGMIAGLVNGQWGFRLPQFINLSGYAWGDEAITV
SQFDTSKDMYDTTFTLIAGNDGSYVLRDRNGIAILSGKVGETVETDTADGPITLHVDKLVGPAGSRFELSRASTLSTVDR
LQKALVVQETTLQSGVIRASLEGGDSALTAAIVNSMAREFVRQDVESRSTEAEHMLAFLDQQLPGLRKELDDAEQRYNKF
RNTHGTVDLGEESRLLLQQIVDNKTKLMDLQQQRAEMSQRFTANHPAVAALDAQIAALQGAAANMNRSVAVMPDTEQTAL
RLLRDVHVDTELYTNLLNSAQQLRVAKAGQVGSVRVVDFAEAPDDPVRPKRVIAILIALGGGLVLGILLTFFKRAMYGGV
ERPDELEGMLGVPVFAVVPRSQTQLKLQENVMLRRRGLHVLAQQAPEDIAVEGVRNLRTSLQLSLDHAENNVVMITGSRP
DSGKSFLSVNLAALVASANKRVLIIDGDMRRGDVHSHFGIGHQPGLSDVLSGGDLNAMIQRDVLPGLDVLAKGTLPSHPA
ELLMSKRFETMLEELKSHYDLVIVDTPPVLAVTDSTLIGKYAGTTLLVVRHGRHPLNEVMETAKRLRNGGVALRGVLLTD
VPQEGAFLGSGYQGGYYGYDSIAG
>Mature_743_residues
AINFENRYTDVSGPDELHLSDYLRTIVRGWRTIAMVTLIALALGCAYAFLAPPTYRADVLFHVEDKTANANANGKDSLPP
LTGMFDTKPSTAAEIELLKSRLVTEETVKKLHLDISAAPRYFPVIGGMIAGLVNGQWGFRLPQFINLSGYAWGDEAITVS
QFDTSKDMYDTTFTLIAGNDGSYVLRDRNGIAILSGKVGETVETDTADGPITLHVDKLVGPAGSRFELSRASTLSTVDRL
QKALVVQETTLQSGVIRASLEGGDSALTAAIVNSMAREFVRQDVESRSTEAEHMLAFLDQQLPGLRKELDDAEQRYNKFR
NTHGTVDLGEESRLLLQQIVDNKTKLMDLQQQRAEMSQRFTANHPAVAALDAQIAALQGAAANMNRSVAVMPDTEQTALR
LLRDVHVDTELYTNLLNSAQQLRVAKAGQVGSVRVVDFAEAPDDPVRPKRVIAILIALGGGLVLGILLTFFKRAMYGGVE
RPDELEGMLGVPVFAVVPRSQTQLKLQENVMLRRRGLHVLAQQAPEDIAVEGVRNLRTSLQLSLDHAENNVVMITGSRPD
SGKSFLSVNLAALVASANKRVLIIDGDMRRGDVHSHFGIGHQPGLSDVLSGGDLNAMIQRDVLPGLDVLAKGTLPSHPAE
LLMSKRFETMLEELKSHYDLVIVDTPPVLAVTDSTLIGKYAGTTLLVVRHGRHPLNEVMETAKRLRNGGVALRGVLLTDV
PQEGAFLGSGYQGGYYGYDSIAG

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the in

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=737, Percent_Identity=35.1424694708277, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787216, Length=716, Percent_Identity=34.7765363128492, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR005700
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 80888; Mature: 80756

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINFENRYTDVSGPDELHLSDYLRTIVRGWRTIAMVTLIALALGCAYAFLAPPTYRADV
CEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LFHVEDKTANANANGKDSLPPLTGMFDTKPSTAAEIELLKSRLVTEETVKKLHLDISAAP
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RYFPVIGGMIAGLVNGQWGFRLPQFINLSGYAWGDEAITVSQFDTSKDMYDTTFTLIAGN
CHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEECCCEEEEEECCCCCCCCCCEEEEEECC
DGSYVLRDRNGIAILSGKVGETVETDTADGPITLHVDKLVGPAGSRFELSRASTLSTVDR
CCCEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCCCEECHHHHHHHHHHH
LQKALVVQETTLQSGVIRASLEGGDSALTAAIVNSMAREFVRQDVESRSTEAEHMLAFLD
HHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QQLPGLRKELDDAEQRYNKFRNTHGTVDLGEESRLLLQQIVDNKTKLMDLQQQRAEMSQR
HHCCHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FTANHPAVAALDAQIAALQGAAANMNRSVAVMPDTEQTALRLLRDVHVDTELYTNLLNSA
HCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHH
QQLRVAKAGQVGSVRVVDFAEAPDDPVRPKRVIAILIALGGGLVLGILLTFFKRAMYGGV
HHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
ERPDELEGMLGVPVFAVVPRSQTQLKLQENVMLRRRGLHVLAQQAPEDIAVEGVRNLRTS
CCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LQLSLDHAENNVVMITGSRPDSGKSFLSVNLAALVASANKRVLIIDGDMRRGDVHSHFGI
HEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
GHQPGLSDVLSGGDLNAMIQRDVLPGLDVLAKGTLPSHPAELLMSKRFETMLEELKSHYD
CCCCCHHHHHCCCCHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
LVIVDTPPVLAVTDSTLIGKYAGTTLLVVRHGRHPLNEVMETAKRLRNGGVALRGVLLTD
EEEECCCCEEEEECCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEEEC
VPQEGAFLGSGYQGGYYGYDSIAG
CCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AINFENRYTDVSGPDELHLSDYLRTIVRGWRTIAMVTLIALALGCAYAFLAPPTYRADV
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LFHVEDKTANANANGKDSLPPLTGMFDTKPSTAAEIELLKSRLVTEETVKKLHLDISAAP
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RYFPVIGGMIAGLVNGQWGFRLPQFINLSGYAWGDEAITVSQFDTSKDMYDTTFTLIAGN
CHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEECCCEEEEEECCCCCCCCCCEEEEEECC
DGSYVLRDRNGIAILSGKVGETVETDTADGPITLHVDKLVGPAGSRFELSRASTLSTVDR
CCCEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCCCEECHHHHHHHHHHH
LQKALVVQETTLQSGVIRASLEGGDSALTAAIVNSMAREFVRQDVESRSTEAEHMLAFLD
HHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QQLPGLRKELDDAEQRYNKFRNTHGTVDLGEESRLLLQQIVDNKTKLMDLQQQRAEMSQR
HHCCHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FTANHPAVAALDAQIAALQGAAANMNRSVAVMPDTEQTALRLLRDVHVDTELYTNLLNSA
HCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHH
QQLRVAKAGQVGSVRVVDFAEAPDDPVRPKRVIAILIALGGGLVLGILLTFFKRAMYGGV
HHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
ERPDELEGMLGVPVFAVVPRSQTQLKLQENVMLRRRGLHVLAQQAPEDIAVEGVRNLRTS
CCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LQLSLDHAENNVVMITGSRPDSGKSFLSVNLAALVASANKRVLIIDGDMRRGDVHSHFGI
HEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
GHQPGLSDVLSGGDLNAMIQRDVLPGLDVLAKGTLPSHPAELLMSKRFETMLEELKSHYD
CCCCCHHHHHCCCCHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
LVIVDTPPVLAVTDSTLIGKYAGTTLLVVRHGRHPLNEVMETAKRLRNGGVALRGVLLTD
EEEECCCCEEEEECCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEEEC
VPQEGAFLGSGYQGGYYGYDSIAG
CCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]