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The map label for this gene is caiD [C]

Identifier: 91781947

GI number: 91781947

Start: 631268

End: 632092

Strand: Reverse

Name: caiD [C]

Synonym: Bxe_A3896

Alternate gene names: 91781947

Gene position: 632092-631268 (Counterclockwise)

Preceding gene: 91781949

Following gene: 91781946

Centisome position: 12.91

GC content: 68.73

Gene sequence:

>825_bases
ATGGTAACCACGCAAAATTTCAATGACCACGTGCGCATCGAAGCTAATGAGGATATCGGCGTCGCCACGATCGTCCTTGA
GCGGCCCGCGCGCCGCAATGCCGTCGATCGTCCTGTCGCGGAAGCGCTCAGCGCCGCGTTCGCCTGCTTCGAAGCCCAGC
CGGCCTGGCGCGCGGCGGTGCTGTTCGGCGCGGGCGGCACTTTCTGCGCCGGCGCGGACCTGACCGCTCTCGCCGACGAC
ACCCGTCGCAACGAACTGCACGCCGACGGCAGCGGTCCCGGCCCGATGGGACCGACGCGCACGAGCTTCAGCAAGCCGGT
GGTCGCCGCGATTGCCGGCTATGCGGTTGCGGGCGGTCTGGAGCTGGCGGCGCTGTGCGATCTGAGAGTGGTCGAAGAAG
ACGCCGTGCTCGGCGTGTTCTGCCGGCGCGTCGGGATTCCGCTGATCGACGGCGGCACGATCCGCCTGCCGCGTCTGATC
GGTCTGTCACGCGCACTGGATCTGATTCTGACGGGCCGCGCGGTGAGCGCGCAGGAAGCGCTCGGCTTCGGTCTCGCCAA
TCGCGTGGTGGCCAAAGGCACGGCTCGCGCCGCAGCCGAACAGTTGGCCGCCGAGCTGGCGGCCTTGCCGCAGGCGACGT
TGCTCGCCGACCGCCGCTCCGTGCTCGAGAACAGCATGCTCGACGATTTCGCCGAAGCGCTGCGTCGTGAAGGCGCTGGC
GGCTATCGAGCCGTCTTTGAAGAAGGTATCGCCGGCGCGGCGCGTTTTGCCGAAGGCACAGGCCGTCACGGCAAGACGCT
CGATGCCGGCGGCGGCACACGCTAG

Upstream 100 bases:

>100_bases
TGTAAGAAGCATGACAGGCCACGGTATTAACTATGCTGCATGAACACACTGCGCGAAAACCCGGATGAACAGGCAAACGC
GGACCGCTATGGAGACAACG

Downstream 100 bases:

>100_bases
ACACTCGTCGGCGCCGGGCACGCCGCCGTTTTCAGCGAAAAACAACAACCGCCCTTACGATCAGCAAGGCTGTTTTGACT
TAGGTAGAATCCCCTACTGT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MVTTQNFNDHVRIEANEDIGVATIVLERPARRNAVDRPVAEALSAAFACFEAQPAWRAAVLFGAGGTFCAGADLTALADD
TRRNELHADGSGPGPMGPTRTSFSKPVVAAIAGYAVAGGLELAALCDLRVVEEDAVLGVFCRRVGIPLIDGGTIRLPRLI
GLSRALDLILTGRAVSAQEALGFGLANRVVAKGTARAAAEQLAAELAALPQATLLADRRSVLENSMLDDFAEALRREGAG
GYRAVFEEGIAGAARFAEGTGRHGKTLDAGGGTR

Sequences:

>Translated_274_residues
MVTTQNFNDHVRIEANEDIGVATIVLERPARRNAVDRPVAEALSAAFACFEAQPAWRAAVLFGAGGTFCAGADLTALADD
TRRNELHADGSGPGPMGPTRTSFSKPVVAAIAGYAVAGGLELAALCDLRVVEEDAVLGVFCRRVGIPLIDGGTIRLPRLI
GLSRALDLILTGRAVSAQEALGFGLANRVVAKGTARAAAEQLAAELAALPQATLLADRRSVLENSMLDDFAEALRREGAG
GYRAVFEEGIAGAARFAEGTGRHGKTLDAGGGTR
>Mature_274_residues
MVTTQNFNDHVRIEANEDIGVATIVLERPARRNAVDRPVAEALSAAFACFEAQPAWRAAVLFGAGGTFCAGADLTALADD
TRRNELHADGSGPGPMGPTRTSFSKPVVAAIAGYAVAGGLELAALCDLRVVEEDAVLGVFCRRVGIPLIDGGTIRLPRLI
GLSRALDLILTGRAVSAQEALGFGLANRVVAKGTARAAAEQLAAELAALPQATLLADRRSVLENSMLDDFAEALRREGAG
GYRAVFEEGIAGAARFAEGTGRHGKTLDAGGGTR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=222, Percent_Identity=31.981981981982, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=32.7586206896552, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=149, Percent_Identity=38.255033557047, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI31542718, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4502327, Length=211, Percent_Identity=32.2274881516588, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI221307494, Length=223, Percent_Identity=25.5605381165919, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI221136756, Length=223, Percent_Identity=25.5605381165919, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI221136753, Length=223, Percent_Identity=25.5605381165919, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI221142681, Length=246, Percent_Identity=32.9268292682927, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787659, Length=188, Percent_Identity=34.5744680851064, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788682, Length=209, Percent_Identity=32.5358851674641, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790281, Length=188, Percent_Identity=29.2553191489362, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=29.9625468164794, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788597, Length=220, Percent_Identity=31.3636363636364, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=250, Percent_Identity=44.8, Blast_Score=192, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=31.3008130081301, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=182, Percent_Identity=34.0659340659341, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=197, Percent_Identity=29.9492385786802, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=183, Percent_Identity=33.879781420765, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=31.1475409836066, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=224, Percent_Identity=28.125, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357171, Length=249, Percent_Identity=46.5863453815261, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24650670, Length=209, Percent_Identity=48.3253588516746, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=31.3253012048193, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=31.3253012048193, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24653139, Length=189, Percent_Identity=34.3915343915344, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24583077, Length=208, Percent_Identity=32.2115384615385, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583079, Length=208, Percent_Identity=32.2115384615385, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921000, Length=192, Percent_Identity=32.2916666666667, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28405; Mature: 28405

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTQNFNDHVRIEANEDIGVATIVLERPARRNAVDRPVAEALSAAFACFEAQPAWRAAV
CCCCCCCCCEEEEEECCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
LFGAGGTFCAGADLTALADDTRRNELHADGSGPGPMGPTRTSFSKPVVAAIAGYAVAGGL
EEECCCCEECCCCCHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
ELAALCDLRVVEEDAVLGVFCRRVGIPLIDGGTIRLPRLIGLSRALDLILTGRAVSAQEA
HHHHHHCCCEECHHHHHHHHHHHHCCCEECCCCEEHHHHHHHHHHHHHHHCCCCCCHHHH
LGFGLANRVVAKGTARAAAEQLAAELAALPQATLLADRRSVLENSMLDDFAEALRREGAG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GYRAVFEEGIAGAARFAEGTGRHGKTLDAGGGTR
CHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MVTTQNFNDHVRIEANEDIGVATIVLERPARRNAVDRPVAEALSAAFACFEAQPAWRAAV
CCCCCCCCCEEEEEECCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
LFGAGGTFCAGADLTALADDTRRNELHADGSGPGPMGPTRTSFSKPVVAAIAGYAVAGGL
EEECCCCEECCCCCHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
ELAALCDLRVVEEDAVLGVFCRRVGIPLIDGGTIRLPRLIGLSRALDLILTGRAVSAQEA
HHHHHHCCCEECHHHHHHHHHHHHCCCEECCCCEEHHHHHHHHHHHHHHHCCCCCCHHHH
LGFGLANRVVAKGTARAAAEQLAAELAALPQATLLADRRSVLENSMLDDFAEALRREGAG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GYRAVFEEGIAGAARFAEGTGRHGKTLDAGGGTR
CHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA